FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5897, 837 aa 1>>>pF1KB5897 837 - 837 aa - 837 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7852+/-0.000528; mu= -11.3979+/- 0.033 mean_var=529.9529+/-109.670, 0's: 0 Z-trim(121.6): 88 B-trim: 696 in 1/60 Lambda= 0.055713 statistics sampled from 38262 (38357) to 38262 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.45), width: 16 Scan time: 13.890 The best scores are: opt bits E(85289) NP_066564 (OMIM: 602301) histone acetyltransferase ( 837) 5659 470.3 1.6e-131 XP_006721880 (OMIM: 602301) PREDICTED: histone ace ( 838) 5647 469.3 3.2e-131 NP_003875 (OMIM: 602303) histone acetyltransferase ( 832) 3941 332.2 6e-90 XP_016862912 (OMIM: 602303) PREDICTED: histone ace ( 735) 3715 313.9 1.6e-84 XP_016862913 (OMIM: 602303) PREDICTED: histone ace ( 735) 3715 313.9 1.6e-84 XP_005265585 (OMIM: 602303) PREDICTED: histone ace ( 741) 3432 291.2 1.2e-77 XP_016879937 (OMIM: 602301) PREDICTED: histone ace ( 476) 3174 270.3 1.5e-71 XP_006721881 (OMIM: 602301) PREDICTED: histone ace ( 477) 3162 269.3 2.9e-71 XP_011522826 (OMIM: 601819) PREDICTED: nucleosome- (2188) 353 44.2 0.0079 XP_016879843 (OMIM: 601819) PREDICTED: nucleosome- (2327) 353 44.2 0.0082 XP_011522828 (OMIM: 601819) PREDICTED: nucleosome- (2776) 353 44.3 0.0093 NP_004450 (OMIM: 601819) nucleosome-remodeling fac (2903) 353 44.3 0.0096 XP_011522827 (OMIM: 601819) PREDICTED: nucleosome- (2919) 353 44.3 0.0097 NP_872579 (OMIM: 601819) nucleosome-remodeling fac (2920) 353 44.3 0.0097 XP_005257218 (OMIM: 601819) PREDICTED: nucleosome- (2957) 353 44.3 0.0097 XP_005257217 (OMIM: 601819) PREDICTED: nucleosome- (2961) 353 44.3 0.0097 XP_011522825 (OMIM: 601819) PREDICTED: nucleosome- (2977) 353 44.3 0.0098 XP_005257216 (OMIM: 601819) PREDICTED: nucleosome- (3015) 353 44.3 0.0099 XP_011522824 (OMIM: 601819) PREDICTED: nucleosome- (3031) 353 44.3 0.0099 XP_005257215 (OMIM: 601819) PREDICTED: nucleosome- (3032) 353 44.3 0.0099 >>NP_066564 (OMIM: 602301) histone acetyltransferase KAT (837 aa) initn: 5659 init1: 5659 opt: 5659 Z-score: 2482.0 bits: 470.3 E(85289): 1.6e-131 Smith-Waterman score: 5659; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:1-837) 10 20 30 40 50 60 pF1KB5 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE 730 740 750 760 770 780 790 800 810 820 830 pF1KB5 RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 790 800 810 820 830 >>XP_006721880 (OMIM: 602301) PREDICTED: histone acetylt (838 aa) initn: 4776 init1: 4561 opt: 5647 Z-score: 2476.8 bits: 469.3 E(85289): 3.2e-131 Smith-Waterman score: 5647; 99.9% identity (99.9% similar) in 838 aa overlap (1-837:1-838) 10 20 30 40 50 60 pF1KB5 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 YTELSHIIKKQKE-IIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPL ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: XP_006 YTELSHIIKKQKEVIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPL 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB5 GKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMT 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB5 ERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 790 800 810 820 830 >>NP_003875 (OMIM: 602303) histone acetyltransferase KAT (832 aa) initn: 3534 init1: 2373 opt: 3941 Z-score: 1735.8 bits: 332.2 E(85289): 6e-90 Smith-Waterman score: 3941; 71.6% identity (86.4% similar) in 821 aa overlap (26-837:22-832) 10 20 30 40 50 60 pF1KB5 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT : : :.::. : :.: : .: :: ::..:. NP_003 MSEAGGAGPGGCGAGAGAGAGPGALP-PQPAALP---PAP-PQGSPCAAAAGGSGA 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC ::... ..::.. :. : . : . .:::.:. :::::::::::.:::::.:.::: NP_003 CGPATAVAAAGTAEGPGGGG---SARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKC 60 70 80 90 100 130 140 150 160 170 pF1KB5 NGWKNPKP-PTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDV ::::::.: :: :: :::: ..:.: :::: : :: ::::::::::.:.:::::.:.:: NP_003 NGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDV 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 ENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSL-GSPPFEKPNIEQGVLNF : :: ::::::.::::::::::::::: ::: .::::::: .::::::.::::: :: NP_003 EYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNF 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 VQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCY :::::::: .::::. ::.:::: .:::.::.:.: : :: .:.. :: :::::::: NP_003 VQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCY 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 CHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPK :.::: ::::::::::.::::.::::.::: ::::::. : ::::: :::::::::::: NP_003 CNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPK 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 FLSMLEEEIYGANSPIWESGFTMPPSE----GTQLVPRPASVSAAVV---PSTPIFSPSM ::::::::.:. :::::.. : :. : : : : :.... :. . .:. NP_003 FLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPN- 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 GGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAA .::.: :.: : ::::: . .. .::.::. ::::::::::.:::: ::::::: NP_003 -AGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAA 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB5 MLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQL ::::::..:::..::::.::::::::.:::::.::::. : :...:.::::::::::::: NP_003 MLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQL 470 480 490 500 510 520 540 550 560 570 580 590 pF1KB5 PRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYG ::::::::.:::::::::::::::::::::::::::::.::::::::::::::::::::: NP_003 PRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYG 530 540 550 560 570 580 600 610 620 630 640 650 pF1KB5 THLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLM ::::::::::::::.:: ::::::::::::::::::::.::.::..:.:::::::::::: NP_003 THLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLM 590 600 610 620 630 640 660 670 680 690 700 710 pF1KB5 ECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGI :::::::::::.: :::::::::::::::::::::::::::::::.::::::.::.::: NP_003 GCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGI 650 660 670 680 690 700 720 730 740 750 760 770 pF1KB5 RETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRF ::::::: ::::.:: .::::::.:::..: :.::: ::::::::::..::: ::::::: NP_003 RETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRF 710 720 730 740 750 760 780 790 800 810 820 830 pF1KB5 PIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE :.:::::.:::..::::..:::.::::::..::.:::::.::: .::. :::::. :.:: NP_003 PMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 770 780 790 800 810 820 pF1KB5 GGLIDK .::::: NP_003 AGLIDK 830 >>XP_016862912 (OMIM: 602303) PREDICTED: histone acetylt (735 aa) initn: 3171 init1: 2373 opt: 3715 Z-score: 1638.3 bits: 313.9 E(85289): 1.6e-84 Smith-Waterman score: 3715; 74.7% identity (88.3% similar) in 734 aa overlap (113-837:4-735) 90 100 110 120 130 140 pF1KB5 QQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKCNGWKNPKP-PTAPRMDLQQPAA ::.:.:::::::::.: :: :: :::: . XP_016 MWTKAEESCKCNGWKNPNPSPTPPRADLQQIIV 10 20 30 150 160 170 180 190 200 pF1KB5 NLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVENLFMSVHKEEDTDTKQVYFYL .:.: :::: : :: ::::::::::.:.:::::.:.::: :: ::::::.::::::::: XP_016 SLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYL 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB5 FKLLRKCILQMTRPVVEGSL-GSPPFEKPNIEQGVLNFVQYKFSHLAPRERQTMFELSKM :::::: ::: .::::::: .::::::.::::: :::::::::: .::::. ::.:: XP_016 FKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKM 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB5 FLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCHVPQSCDSLPRYETTHVFGRS :: .:::.::.:.: : :: .:.. :: :::::::::.::: ::::::::::.::::. XP_016 FLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRT 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB5 LLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFT ::::.::: ::::::. : ::::: ::::::::::::::::::::.:. :::::.. : XP_016 LLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFL 220 230 240 250 260 270 390 400 410 420 430 pF1KB5 MPPSE----GTQLVPRPASVSAAVV---PSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEK :. : : : : :.... :. . .:. .::.: :.: : :::: XP_016 SASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPN--AGSSSPACKASSGLEANPGEK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB5 RTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLE : . .. .::.::. ::::::::::.:::: :::::::::::::..:::..::::.:::: XP_016 RKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLE 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB5 ERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLAL ::::.:::::.::::. : :...:.:::::::::::::::::::::.::::::::::::: XP_016 ERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLAL 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB5 IKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTY ::::::::::::::::.:::::::::::::::::::::::::::::::::::.:: :::: XP_016 IKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTY 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB5 ADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKE ::::::::::::::::.::.::..:.:::::::::::: :::::::::::.: ::::::: XP_016 ADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKE 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB5 IIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQL ::::::::::::::::::::::::.::::::.::.:::::::::: ::::.:: .::::: XP_016 IIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQL 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB5 YTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLF :.:::..: :.::: ::::::::::..::: ::::::::.:::::.:::..::::..::: XP_016 YSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLF 640 650 660 670 680 690 800 810 820 830 pF1KB5 VADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK .::::::..::.:::::.::: .::. :::::. :.::.::::: XP_016 MADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 700 710 720 730 >>XP_016862913 (OMIM: 602303) PREDICTED: histone acetylt (735 aa) initn: 3171 init1: 2373 opt: 3715 Z-score: 1638.3 bits: 313.9 E(85289): 1.6e-84 Smith-Waterman score: 3715; 74.7% identity (88.3% similar) in 734 aa overlap (113-837:4-735) 90 100 110 120 130 140 pF1KB5 QQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKCNGWKNPKP-PTAPRMDLQQPAA ::.:.:::::::::.: :: :: :::: . XP_016 MWTKAEESCKCNGWKNPNPSPTPPRADLQQIIV 10 20 30 150 160 170 180 190 200 pF1KB5 NLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVENLFMSVHKEEDTDTKQVYFYL .:.: :::: : :: ::::::::::.:.:::::.:.::: :: ::::::.::::::::: XP_016 SLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYL 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB5 FKLLRKCILQMTRPVVEGSL-GSPPFEKPNIEQGVLNFVQYKFSHLAPRERQTMFELSKM :::::: ::: .::::::: .::::::.::::: :::::::::: .::::. ::.:: XP_016 FKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKM 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB5 FLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCHVPQSCDSLPRYETTHVFGRS :: .:::.::.:.: : :: .:.. :: :::::::::.::: ::::::::::.::::. XP_016 FLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRT 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB5 LLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFT ::::.::: ::::::. : ::::: ::::::::::::::::::::.:. :::::.. : XP_016 LLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFL 220 230 240 250 260 270 390 400 410 420 430 pF1KB5 MPPSE----GTQLVPRPASVSAAVV---PSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEK :. : : : : :.... :. . .:. .::.: :.: : :::: XP_016 SASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPN--AGSSSPACKASSGLEANPGEK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB5 RTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLE : . .. .::.::. ::::::::::.:::: :::::::::::::..:::..::::.:::: XP_016 RKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLE 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB5 ERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLAL ::::.:::::.::::. : :...:.:::::::::::::::::::::.::::::::::::: XP_016 ERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLAL 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB5 IKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTY ::::::::::::::::.:::::::::::::::::::::::::::::::::::.:: :::: XP_016 IKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTY 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB5 ADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKE ::::::::::::::::.::.::..:.:::::::::::: :::::::::::.: ::::::: XP_016 ADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKE 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB5 IIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQL ::::::::::::::::::::::::.::::::.::.:::::::::: ::::.:: .::::: XP_016 IIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQL 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB5 YTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLF :.:::..: :.::: ::::::::::..::: ::::::::.:::::.:::..::::..::: XP_016 YSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLF 640 650 660 670 680 690 800 810 820 830 pF1KB5 VADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK .::::::..::.:::::.::: .::. :::::. :.::.::::: XP_016 MADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 700 710 720 730 >>XP_005265585 (OMIM: 602303) PREDICTED: histone acetylt (741 aa) initn: 3025 init1: 1864 opt: 3432 Z-score: 1515.3 bits: 291.2 E(85289): 1.2e-77 Smith-Waterman score: 3432; 71.2% identity (85.3% similar) in 729 aa overlap (26-745:22-740) 10 20 30 40 50 60 pF1KB5 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT : : :.::. : :.: : .: :: ::..:. XP_005 MSEAGGAGPGGCGAGAGAGAGPGALP-PQPAALP---PAP-PQGSPCAAAAGGSGA 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC ::... ..::.. :. : . : . .:::.:. :::::::::::.:::::.:.::: XP_005 CGPATAVAAAGTAEGPGGGG---SARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKC 60 70 80 90 100 130 140 150 160 170 pF1KB5 NGWKNPKP-PTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDV ::::::.: :: :: :::: ..:.: :::: : :: ::::::::::.:.:::::.:.:: XP_005 NGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDV 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 ENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSL-GSPPFEKPNIEQGVLNF : :: ::::::.::::::::::::::: ::: .::::::: .::::::.::::: :: XP_005 EYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNF 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 VQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCY :::::::: .::::. ::.:::: .:::.::.:.: : :: .:.. :: :::::::: XP_005 VQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCY 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 CHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPK :.::: ::::::::::.::::.::::.::: ::::::. : ::::: :::::::::::: XP_005 CNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPK 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 FLSMLEEEIYGANSPIWESGFTMPPSE----GTQLVPRPASVSAAVV---PSTPIFSPSM ::::::::.:. :::::.. : :. : : : : :.... :. . .:. XP_005 FLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPN- 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 GGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAA .::.: :.: : ::::: . .. .::.::. ::::::::::.:::: ::::::: XP_005 -AGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAA 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB5 MLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQL ::::::..:::..::::.::::::::.:::::.::::. : :...:.::::::::::::: XP_005 MLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQL 470 480 490 500 510 520 540 550 560 570 580 590 pF1KB5 PRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYG ::::::::.:::::::::::::::::::::::::::::.::::::::::::::::::::: XP_005 PRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYG 530 540 550 560 570 580 600 610 620 630 640 650 pF1KB5 THLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLM ::::::::::::::.:: ::::::::::::::::::::.::.::..:.:::::::::::: XP_005 THLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLM 590 600 610 620 630 640 660 670 680 690 700 710 pF1KB5 ECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGI :::::::::::.: :::::::::::::::::::::::::::::::.::::::.::.::: XP_005 GCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGI 650 660 670 680 690 700 720 730 740 750 760 770 pF1KB5 RETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRF ::::::: ::::.:: .::::::.:::..: :.: XP_005 RETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKI 710 720 730 740 780 790 800 810 820 830 pF1KB5 PIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE >>XP_016879937 (OMIM: 602301) PREDICTED: histone acetylt (476 aa) initn: 3174 init1: 3174 opt: 3174 Z-score: 1405.7 bits: 270.3 E(85289): 1.5e-71 Smith-Waterman score: 3174; 100.0% identity (100.0% similar) in 476 aa overlap (362-837:1-476) 340 350 360 370 380 390 pF1KB5 QLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFTMPPSEGTQLVP :::::::::::::::::::::::::::::: XP_016 MLEEEIYGANSPIWESGFTMPPSEGTQLVP 10 20 30 400 410 420 430 440 450 pF1KB5 RPASVSAAVVPSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPASVSAAVVPSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVM 40 50 60 70 80 90 460 470 480 490 500 510 pF1KB5 GDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPK 100 110 120 130 140 150 520 530 540 550 560 570 pF1KB5 ANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQ 160 170 180 190 200 210 580 590 600 610 620 630 pF1KB5 GFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDI 220 230 240 250 260 270 640 650 660 670 680 690 pF1KB5 KVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYP 280 290 300 310 320 330 700 710 720 730 740 750 pF1KB5 GLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAW 340 350 360 370 380 390 760 770 780 790 800 810 pF1KB5 PFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPD 400 410 420 430 440 450 820 830 pF1KB5 SEYCRCASALEKFFYFKLKEGGLIDK :::::::::::::::::::::::::: XP_016 SEYCRCASALEKFFYFKLKEGGLIDK 460 470 >>XP_006721881 (OMIM: 602301) PREDICTED: histone acetylt (477 aa) initn: 2168 init1: 2076 opt: 3162 Z-score: 1400.5 bits: 269.3 E(85289): 2.9e-71 Smith-Waterman score: 3162; 99.8% identity (99.8% similar) in 477 aa overlap (362-837:1-477) 340 350 360 370 380 390 pF1KB5 QLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFTMPPSEGTQLVP :::::::::::::::::::::::::::::: XP_006 MLEEEIYGANSPIWESGFTMPPSEGTQLVP 10 20 30 400 410 420 430 440 450 pF1KB5 RPASVSAAVVPSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPASVSAAVVPSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVM 40 50 60 70 80 90 460 470 480 490 500 510 pF1KB5 GDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPK 100 110 120 130 140 150 520 530 540 550 560 570 pF1KB5 ANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQ 160 170 180 190 200 210 580 590 600 610 620 630 pF1KB5 GFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDI 220 230 240 250 260 270 640 650 660 670 680 690 pF1KB5 KVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKE-IIKKLIERKQAQIRKVY :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_006 KVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEVIIKKLIERKQAQIRKVY 280 290 300 310 320 330 700 710 720 730 740 750 pF1KB5 PGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSA 340 350 360 370 380 390 760 770 780 790 800 810 pF1KB5 WPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPP 400 410 420 430 440 450 820 830 pF1KB5 DSEYCRCASALEKFFYFKLKEGGLIDK ::::::::::::::::::::::::::: XP_006 DSEYCRCASALEKFFYFKLKEGGLIDK 460 470 >>XP_011522826 (OMIM: 601819) PREDICTED: nucleosome-remo (2188 aa) initn: 442 init1: 353 opt: 353 Z-score: 171.8 bits: 44.2 E(85289): 0.0079 Smith-Waterman score: 353; 51.5% identity (72.2% similar) in 97 aa overlap (734-830:2075-2171) 710 720 730 740 750 760 pF1KB5 PVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAP : :: .: ....: ::::.::: ..:: XP_011 EAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAP 2050 2060 2070 2080 2090 2100 770 780 790 800 810 820 pF1KB5 DYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEK ::: ::. :.:: :: ::.. ::: ::::. ... ::: ::: :: . .:: .::. XP_011 DYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLES 2110 2120 2130 2140 2150 2160 830 pF1KB5 FFYFKLKEGGLIDK :: ::: XP_011 FFVQKLKGFKASRSHNNKLQSTAS 2170 2180 >>XP_016879843 (OMIM: 601819) PREDICTED: nucleosome-remo (2327 aa) initn: 442 init1: 353 opt: 353 Z-score: 171.5 bits: 44.2 E(85289): 0.0082 Smith-Waterman score: 353; 51.5% identity (72.2% similar) in 97 aa overlap (734-830:2214-2310) 710 720 730 740 750 760 pF1KB5 PVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAP : :: .: ....: ::::.::: ..:: XP_016 EAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAP 2190 2200 2210 2220 2230 2240 770 780 790 800 810 820 pF1KB5 DYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEK ::: ::. :.:: :: ::.. ::: ::::. ... ::: ::: :: . .:: .::. XP_016 DYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLES 2250 2260 2270 2280 2290 2300 830 pF1KB5 FFYFKLKEGGLIDK :: ::: XP_016 FFVQKLKGFKASRSHNNKLQSTAS 2310 2320 837 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:23:56 2016 done: Sat Nov 5 16:23:58 2016 Total Scan time: 13.890 Total Display time: 0.190 Function used was FASTA [36.3.4 Apr, 2011]