FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5902, 525 aa 1>>>pF1KB5902 525 - 525 aa - 525 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7632+/-0.000347; mu= 4.5964+/- 0.022 mean_var=236.9676+/-47.060, 0's: 0 Z-trim(122.8): 14 B-trim: 94 in 1/57 Lambda= 0.083316 statistics sampled from 41537 (41551) to 41537 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.487), width: 16 Scan time: 11.390 The best scores are: opt bits E(85289) NP_002277 (OMIM: 153337) lymphocyte activation gen ( 525) 3691 456.5 9.2e-128 XP_011519258 (OMIM: 153337) PREDICTED: lymphocyte ( 444) 2514 314.9 3.2e-85 >>NP_002277 (OMIM: 153337) lymphocyte activation gene 3 (525 aa) initn: 3691 init1: 3691 opt: 3691 Z-score: 2414.7 bits: 456.5 E(85289): 9.2e-128 Smith-Waterman score: 3691; 100.0% identity (100.0% similar) in 525 aa overlap (1-525:1-525) 10 20 30 40 50 60 pF1KB5 MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 CILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 PGSLGKLLCEVTPVSGQERFVWSSLDTPSQRSFSGPWLEAQEAQLLSQPWQCQLYQGERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PGSLGKLLCEVTPVSGQERFVWSSLDTPSQRSFSGPWLEAQEAQLLSQPWQCQLYQGERL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LGAAVYFTELSSPGAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LGAAVYFTELSSPGAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRP 430 440 450 460 470 480 490 500 510 520 pF1KB5 RRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL ::::::::::::::::::::::::::::::::::::::::::::: NP_002 RRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL 490 500 510 520 >>XP_011519258 (OMIM: 153337) PREDICTED: lymphocyte acti (444 aa) initn: 2639 init1: 2510 opt: 2514 Z-score: 1651.0 bits: 314.9 E(85289): 3.2e-85 Smith-Waterman score: 2961; 84.6% identity (84.6% similar) in 525 aa overlap (1-525:1-444) 10 20 30 40 50 60 pF1KB5 MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 CILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGS :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIIT-------- 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 PGSLGKLLCEVTPVSGQERFVWSSLDTPSQRSFSGPWLEAQEAQLLSQPWQCQLYQGERL XP_011 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KB5 LGAAVYFTELSSPGAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRP ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -------------GAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRP 360 370 380 390 490 500 510 520 pF1KB5 RRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL ::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL 400 410 420 430 440 525 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:30:05 2016 done: Sat Nov 5 15:30:07 2016 Total Scan time: 11.390 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]