FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5908, 520 aa 1>>>pF1KB5908 520 - 520 aa - 520 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0519+/-0.000343; mu= 6.6182+/- 0.022 mean_var=182.3791+/-37.878, 0's: 0 Z-trim(120.1): 80 B-trim: 1966 in 1/58 Lambda= 0.094970 statistics sampled from 34808 (34922) to 34808 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.409), width: 16 Scan time: 8.930 The best scores are: opt bits E(85289) NP_937802 (OMIM: 103470,103500,156845,193510,61445 ( 520) 3424 481.5 2.6e-135 XP_016861934 (OMIM: 103470,103500,156845,193510,61 ( 519) 3407 479.2 1.3e-134 XP_005264811 (OMIM: 103470,103500,156845,193510,61 ( 526) 3402 478.5 2.1e-134 XP_011532024 (OMIM: 103470,103500,156845,193510,61 ( 525) 3385 476.2 1.1e-133 XP_016861936 (OMIM: 103470,103500,156845,193510,61 ( 503) 3209 452.0 1.9e-126 NP_006713 (OMIM: 103470,103500,156845,193510,61445 ( 519) 3197 450.4 6e-126 NP_937820 (OMIM: 103470,103500,156845,193510,61445 ( 504) 3192 449.7 9.5e-126 XP_016861935 (OMIM: 103470,103500,156845,193510,61 ( 509) 3187 449.0 1.5e-125 XP_016861933 (OMIM: 103470,103500,156845,193510,61 ( 525) 3175 447.4 4.9e-125 XP_005264812 (OMIM: 103470,103500,156845,193510,61 ( 510) 3170 446.7 7.7e-125 XP_011532025 (OMIM: 103470,103500,156845,193510,61 ( 509) 3165 446.0 1.2e-124 NP_001171896 (OMIM: 103470,103500,156845,193510,61 ( 468) 3082 434.6 3.1e-121 XP_016861937 (OMIM: 103470,103500,156845,193510,61 ( 468) 3082 434.6 3.1e-121 XP_006713227 (OMIM: 103470,103500,156845,193510,61 ( 474) 3060 431.6 2.5e-120 NP_937801 (OMIM: 103470,103500,156845,193510,61445 ( 413) 2667 377.7 3.7e-104 NP_000239 (OMIM: 103470,103500,156845,193510,61445 ( 419) 2645 374.7 3e-103 XP_011532028 (OMIM: 103470,103500,156845,193510,61 ( 464) 2166 309.1 1.9e-83 NP_937821 (OMIM: 103470,103500,156845,193510,61445 ( 357) 2146 306.3 1e-82 XP_011532027 (OMIM: 103470,103500,156845,193510,61 ( 470) 2144 306.1 1.5e-82 NP_006512 (OMIM: 300854,314310) transcription fact ( 575) 1018 151.9 4.9e-36 XP_011514274 (OMIM: 604732) PREDICTED: transcripti ( 287) 971 145.2 2.5e-34 NP_036384 (OMIM: 604732) transcription factor EC i ( 347) 972 145.4 2.6e-34 XP_016867364 (OMIM: 604732) PREDICTED: transcripti ( 347) 972 145.4 2.6e-34 XP_011514266 (OMIM: 604732) PREDICTED: transcripti ( 437) 972 145.5 3.1e-34 XP_011514265 (OMIM: 604732) PREDICTED: transcripti ( 437) 972 145.5 3.1e-34 XP_011514268 (OMIM: 604732) PREDICTED: transcripti ( 437) 972 145.5 3.1e-34 XP_011514267 (OMIM: 604732) PREDICTED: transcripti ( 437) 972 145.5 3.1e-34 NP_001269071 (OMIM: 300854,314310) transcription f ( 470) 940 141.1 6.9e-33 XP_016867365 (OMIM: 604732) PREDICTED: transcripti ( 259) 899 135.3 2.1e-31 NP_001231512 (OMIM: 604732) transcription factor E ( 280) 899 135.3 2.3e-31 NP_001018068 (OMIM: 604732) transcription factor E ( 318) 899 135.4 2.5e-31 XP_016867363 (OMIM: 604732) PREDICTED: transcripti ( 408) 899 135.5 3e-31 XP_011514272 (OMIM: 604732) PREDICTED: transcripti ( 408) 899 135.5 3e-31 XP_016867366 (OMIM: 604732) PREDICTED: transcripti ( 239) 858 129.7 9.9e-30 XP_016867367 (OMIM: 604732) PREDICTED: transcripti ( 239) 858 129.7 9.9e-30 XP_006715276 (OMIM: 600744) PREDICTED: transcripti ( 476) 770 117.8 7.1e-26 NP_001258873 (OMIM: 600744) transcription factor E ( 476) 770 117.8 7.1e-26 XP_005249469 (OMIM: 600744) PREDICTED: transcripti ( 476) 770 117.8 7.1e-26 XP_011513218 (OMIM: 600744) PREDICTED: transcripti ( 476) 770 117.8 7.1e-26 XP_011513217 (OMIM: 600744) PREDICTED: transcripti ( 476) 770 117.8 7.1e-26 NP_001258874 (OMIM: 600744) transcription factor E ( 476) 770 117.8 7.1e-26 XP_006715275 (OMIM: 600744) PREDICTED: transcripti ( 476) 770 117.8 7.1e-26 NP_009093 (OMIM: 600744) transcription factor EB i ( 476) 770 117.8 7.1e-26 XP_005249468 (OMIM: 600744) PREDICTED: transcripti ( 476) 770 117.8 7.1e-26 NP_001161299 (OMIM: 600744) transcription factor E ( 490) 770 117.8 7.3e-26 NP_001258872 (OMIM: 600744) transcription factor E ( 391) 758 116.1 1.9e-25 XP_011514271 (OMIM: 604732) PREDICTED: transcripti ( 418) 679 105.3 3.7e-22 NP_001171897 (OMIM: 103470,103500,156845,193510,61 ( 91) 527 84.0 2.1e-16 >>NP_937802 (OMIM: 103470,103500,156845,193510,614456) m (520 aa) initn: 3424 init1: 3424 opt: 3424 Z-score: 2550.2 bits: 481.5 E(85289): 2.6e-135 Smith-Waterman score: 3424; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520) 10 20 30 40 50 60 pF1KB5 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 AKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 EQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 VLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 VLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILM 430 440 450 460 470 480 490 500 510 520 pF1KB5 DDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC :::::::::::::::::::::::::::::::::::::::: NP_937 DDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 490 500 510 520 >>XP_016861934 (OMIM: 103470,103500,156845,193510,614456 (519 aa) initn: 3197 init1: 3197 opt: 3407 Z-score: 2537.6 bits: 479.2 E(85289): 1.3e-134 Smith-Waterman score: 3407; 99.8% identity (99.8% similar) in 520 aa overlap (1-520:1-519) 10 20 30 40 50 60 pF1KB5 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLR :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSS-AEHPGASKPPISSSSMTSRILLR 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 AKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 EQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEP 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 VLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILM 420 430 440 450 460 470 490 500 510 520 pF1KB5 DDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC :::::::::::::::::::::::::::::::::::::::: XP_016 DDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 480 490 500 510 >>XP_005264811 (OMIM: 103470,103500,156845,193510,614456 (526 aa) initn: 1952 init1: 1952 opt: 3402 Z-score: 2533.8 bits: 478.5 E(85289): 2.1e-134 Smith-Waterman score: 3402; 98.9% identity (98.9% similar) in 526 aa overlap (1-520:1-526) 10 20 30 40 50 60 pF1KB5 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELT------E ::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_005 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 SEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDY 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 IRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 IIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK 430 440 450 460 470 480 480 490 500 510 520 pF1KB5 LEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC :::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 490 500 510 520 >>XP_011532024 (OMIM: 103470,103500,156845,193510,614456 (525 aa) initn: 1755 init1: 1725 opt: 3385 Z-score: 2521.2 bits: 476.2 E(85289): 1.1e-133 Smith-Waterman score: 3385; 98.7% identity (98.7% similar) in 526 aa overlap (1-520:1-525) 10 20 30 40 50 60 pF1KB5 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLR :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_011 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSS-AEHPGASKPPISSSSMTSRILLR 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE 180 190 200 210 220 230 250 260 270 280 290 pF1KB5 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELT------E ::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 SEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDY 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 IRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNR 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 IIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK 420 430 440 450 460 470 480 490 500 510 520 pF1KB5 LEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC :::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 480 490 500 510 520 >>XP_016861936 (OMIM: 103470,103500,156845,193510,614456 (503 aa) initn: 3209 init1: 3209 opt: 3209 Z-score: 2391.2 bits: 452.0 E(85289): 1.9e-126 Smith-Waterman score: 3209; 98.4% identity (99.0% similar) in 497 aa overlap (24-520:7-503) 10 20 30 40 50 60 pF1KB5 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLR . .: : : .:::::::::::::::::::::::::: XP_016 MDWAINFVHLPSCALMASSSAEHPGASKPPISSSSMTSRILLR 10 20 30 40 70 80 90 100 110 120 pF1KB5 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARAL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 AKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQR 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 EQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEP 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 VLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILM 410 420 430 440 450 460 490 500 510 520 pF1KB5 DDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC :::::::::::::::::::::::::::::::::::::::: XP_016 DDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 470 480 490 500 >>NP_006713 (OMIM: 103470,103500,156845,193510,614456) m (519 aa) initn: 3197 init1: 3197 opt: 3197 Z-score: 2382.1 bits: 450.4 E(85289): 6e-126 Smith-Waterman score: 3197; 100.0% identity (100.0% similar) in 486 aa overlap (35-520:34-519) 10 20 30 40 50 60 pF1KB5 SGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLRQQLM :::::::::::::::::::::::::::::: NP_006 LENTSVVFPRAIFSLCEKETRKLTLCLFSRSSSAEHPGASKPPISSSSMTSRILLRQQLM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 REQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 REQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 QKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 AKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 CSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 CSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTL 430 440 450 460 470 480 490 500 510 520 pF1KB5 SPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC :::::::::::::::::::::::::::::::::::: NP_006 SPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 490 500 510 >>NP_937820 (OMIM: 103470,103500,156845,193510,614456) m (504 aa) initn: 3192 init1: 3192 opt: 3192 Z-score: 2378.6 bits: 449.7 E(85289): 9.5e-126 Smith-Waterman score: 3192; 100.0% identity (100.0% similar) in 485 aa overlap (36-520:20-504) 10 20 30 40 50 60 pF1KB5 GIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLRQQLMR :::::::::::::::::::::::::::::: NP_937 MEALRVQMFMPCSFESLYLSSAEHPGASKPPISSSSMTSRILLRQQLMR 10 20 30 40 70 80 90 100 110 120 pF1KB5 EQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLEN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 PTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAML 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 TLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 TLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 DPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 DPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 KKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRA 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 KELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENC 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 SQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLS 410 420 430 440 450 460 490 500 510 520 pF1KB5 PVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC ::::::::::::::::::::::::::::::::::: NP_937 PVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 470 480 490 500 >>XP_016861935 (OMIM: 103470,103500,156845,193510,614456 (509 aa) initn: 1737 init1: 1737 opt: 3187 Z-score: 2374.8 bits: 449.0 E(85289): 1.5e-125 Smith-Waterman score: 3187; 97.2% identity (97.8% similar) in 503 aa overlap (24-520:7-509) 10 20 30 40 50 60 pF1KB5 MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLR . .: : : .:::::::::::::::::::::::::: XP_016 MDWAINFVHLPSCALMASSSAEHPGASKPPISSSSMTSRILLR 10 20 30 40 70 80 90 100 110 120 pF1KB5 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEE 170 180 190 200 210 220 250 260 270 280 290 pF1KB5 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELT------E ::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 ILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTE 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 SEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDY 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 IRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNR 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 IIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK 410 420 430 440 450 460 480 490 500 510 520 pF1KB5 LEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC :::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 470 480 490 500 >>XP_016861933 (OMIM: 103470,103500,156845,193510,614456 (525 aa) initn: 1725 init1: 1725 opt: 3175 Z-score: 2365.7 bits: 447.4 E(85289): 4.9e-125 Smith-Waterman score: 3175; 98.8% identity (98.8% similar) in 492 aa overlap (35-520:34-525) 10 20 30 40 50 60 pF1KB5 SGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLRQQLM :::::::::::::::::::::::::::::: XP_016 LENTSVVFPRAIFSLCEKETRKLTLCLFSRSSSAEHPGASKPPISSSSMTSRILLRQQLM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 REQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGL 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 MDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELT------ESEAR ::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 MDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTESEAR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 ALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 QREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 EPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDI 430 440 450 460 470 480 480 490 500 510 520 pF1KB5 LMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC :::::::::::::::::::::::::::::::::::::::::: XP_016 LMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 490 500 510 520 >>XP_005264812 (OMIM: 103470,103500,156845,193510,614456 (510 aa) initn: 1720 init1: 1720 opt: 3170 Z-score: 2362.2 bits: 446.7 E(85289): 7.7e-125 Smith-Waterman score: 3170; 98.8% identity (98.8% similar) in 491 aa overlap (36-520:20-510) 10 20 30 40 50 60 pF1KB5 GIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLRQQLMR :::::::::::::::::::::::::::::: XP_005 MEALRVQMFMPCSFESLYLSSAEHPGASKPPISSSSMTSRILLRQQLMR 10 20 30 40 70 80 90 100 110 120 pF1KB5 EQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLEN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 PTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAML 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 TLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLM 170 180 190 200 210 220 250 260 270 280 290 pF1KB5 DPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELT------ESEARA :::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_005 DPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTESEARA 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 LAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQ 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 REQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQE 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 PVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDIL 410 420 430 440 450 460 480 490 500 510 520 pF1KB5 MDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC ::::::::::::::::::::::::::::::::::::::::: XP_005 MDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 470 480 490 500 510 520 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:38:53 2016 done: Sat Nov 5 10:38:54 2016 Total Scan time: 8.930 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]