Result of FASTA (omim) for
pF1KB5913
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5913, 504 aa
1>>>pF1KB5913 504 - 504 aa - 504 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6720+/-0.000387; mu= 15.6545+/- 0.024
mean_var=59.8063+/-12.168, 0's: 0 Z-trim(110.7): 31 B-trim: 999 in 1/55
Lambda= 0.165844
statistics sampled from 19037 (19059) to 19037 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.591), E-opt: 0.2 (0.223), width: 16
Scan time: 9.170
The best scores are: opt bits E(85289)
NP_005403 (OMIM: 138450) serine hydroxymethyltrans ( 504) 3343 808.6 0
NP_001159830 (OMIM: 138450) serine hydroxymethyltr ( 483) 3191 772.2 0
NP_001159829 (OMIM: 138450) serine hydroxymethyltr ( 483) 3191 772.2 0
NP_001159831 (OMIM: 138450) serine hydroxymethyltr ( 483) 3191 772.2 0
XP_005256824 (OMIM: 182144) PREDICTED: serine hydr ( 483) 2033 495.2 1.8e-139
XP_016880446 (OMIM: 182144) PREDICTED: serine hydr ( 483) 2033 495.2 1.8e-139
NP_004160 (OMIM: 182144) serine hydroxymethyltrans ( 483) 2033 495.2 1.8e-139
XP_011536980 (OMIM: 138450) PREDICTED: serine hydr ( 408) 1992 485.4 1.4e-136
XP_011536977 (OMIM: 138450) PREDICTED: serine hydr ( 408) 1992 485.4 1.4e-136
XP_011536978 (OMIM: 138450) PREDICTED: serine hydr ( 408) 1992 485.4 1.4e-136
XP_011536979 (OMIM: 138450) PREDICTED: serine hydr ( 408) 1992 485.4 1.4e-136
NP_001159828 (OMIM: 138450) serine hydroxymethyltr ( 494) 1917 467.4 4.2e-131
NP_001268715 (OMIM: 182144) serine hydroxymethyltr ( 345) 1457 357.3 4e-98
XP_016880447 (OMIM: 182144) PREDICTED: serine hydr ( 444) 1256 309.3 1.5e-83
NP_683718 (OMIM: 182144) serine hydroxymethyltrans ( 444) 1256 309.3 1.5e-83
XP_011522294 (OMIM: 182144) PREDICTED: serine hydr ( 403) 1251 308.1 3.2e-83
XP_016880448 (OMIM: 182144) PREDICTED: serine hydr ( 306) 680 171.4 3.3e-42
XP_016880449 (OMIM: 182144) PREDICTED: serine hydr ( 265) 675 170.2 6.6e-42
>>NP_005403 (OMIM: 138450) serine hydroxymethyltransfera (504 aa)
initn: 3343 init1: 3343 opt: 3343 Z-score: 4318.6 bits: 808.6 E(85289): 0
Smith-Waterman score: 3343; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KB5 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
430 440 450 460 470 480
490 500
pF1KB5 RLANLRQRVEQFARAFPMPGFDEH
::::::::::::::::::::::::
NP_005 RLANLRQRVEQFARAFPMPGFDEH
490 500
>>NP_001159830 (OMIM: 138450) serine hydroxymethyltransf (483 aa)
initn: 3191 init1: 3191 opt: 3191 Z-score: 4122.3 bits: 772.2 E(85289): 0
Smith-Waterman score: 3191; 100.0% identity (100.0% similar) in 483 aa overlap (22-504:1-483)
10 20 30 40 50 60
pF1KB5 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
:::::::::::::::::::::::::::::::::::::::
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
10 20 30
70 80 90 100 110 120
pF1KB5 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
400 410 420 430 440 450
490 500
pF1KB5 RLANLRQRVEQFARAFPMPGFDEH
::::::::::::::::::::::::
NP_001 RLANLRQRVEQFARAFPMPGFDEH
460 470 480
>>NP_001159829 (OMIM: 138450) serine hydroxymethyltransf (483 aa)
initn: 3191 init1: 3191 opt: 3191 Z-score: 4122.3 bits: 772.2 E(85289): 0
Smith-Waterman score: 3191; 100.0% identity (100.0% similar) in 483 aa overlap (22-504:1-483)
10 20 30 40 50 60
pF1KB5 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
:::::::::::::::::::::::::::::::::::::::
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
10 20 30
70 80 90 100 110 120
pF1KB5 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
400 410 420 430 440 450
490 500
pF1KB5 RLANLRQRVEQFARAFPMPGFDEH
::::::::::::::::::::::::
NP_001 RLANLRQRVEQFARAFPMPGFDEH
460 470 480
>>NP_001159831 (OMIM: 138450) serine hydroxymethyltransf (483 aa)
initn: 3191 init1: 3191 opt: 3191 Z-score: 4122.3 bits: 772.2 E(85289): 0
Smith-Waterman score: 3191; 100.0% identity (100.0% similar) in 483 aa overlap (22-504:1-483)
10 20 30 40 50 60
pF1KB5 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
:::::::::::::::::::::::::::::::::::::::
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
10 20 30
70 80 90 100 110 120
pF1KB5 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
400 410 420 430 440 450
490 500
pF1KB5 RLANLRQRVEQFARAFPMPGFDEH
::::::::::::::::::::::::
NP_001 RLANLRQRVEQFARAFPMPGFDEH
460 470 480
>>XP_005256824 (OMIM: 182144) PREDICTED: serine hydroxym (483 aa)
initn: 2040 init1: 1950 opt: 2033 Z-score: 2625.0 bits: 495.2 E(85289): 1.8e-139
Smith-Waterman score: 2033; 66.1% identity (85.4% similar) in 460 aa overlap (47-503:24-482)
20 30 40 50 60 70
pF1KB5 GQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIAS
. :.::: :.......:..:: :::::::
XP_005 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIAS
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 ENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGV
::: :::.::::::::::::::::::.:::::.: .::.: :::.:::.:. ::: :::
XP_005 ENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGV
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB5 NVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYK
:::::::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::
XP_005 NVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYK
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB5 LNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHIS
.:: :: :.:.:: .::::.:.::::::: :.: ..:::.:.. :: :.:.:::::::
XP_005 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB5 GLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRIN
::::: :.::::.: .::::::::::: :.:.::::::::.::::::.:: :..:. ::
XP_005 GLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLIN
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB5 FAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGG
::::.:::::::::::.:::::::: : :. :. ::. : ::...:: : ::..:.::
XP_005 SAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGG
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB5 TDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQF
.::::.::::: :: ::.:::.::: ::. :::::::::::. :.:::::.:::::: .
XP_005 SDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGL
360 370 380 390 400 410
440 450 460 470 480 490
pF1KB5 REDDFRRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFA
: ::..:. :: .:... :...: : : :..:: : :. . : ::..::.::
XP_005 LEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFA
420 430 440 450 460 470
500
pF1KB5 RAFPMPGFDEH
::.::. .
XP_005 SLFPLPGLPDF
480
>>XP_016880446 (OMIM: 182144) PREDICTED: serine hydroxym (483 aa)
initn: 2040 init1: 1950 opt: 2033 Z-score: 2625.0 bits: 495.2 E(85289): 1.8e-139
Smith-Waterman score: 2033; 66.1% identity (85.4% similar) in 460 aa overlap (47-503:24-482)
20 30 40 50 60 70
pF1KB5 GQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIAS
. :.::: :.......:..:: :::::::
XP_016 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIAS
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 ENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGV
::: :::.::::::::::::::::::.:::::.: .::.: :::.:::.:. ::: :::
XP_016 ENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGV
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB5 NVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYK
:::::::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::
XP_016 NVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYK
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB5 LNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHIS
.:: :: :.:.:: .::::.:.::::::: :.: ..:::.:.. :: :.:.:::::::
XP_016 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB5 GLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRIN
::::: :.::::.: .::::::::::: :.:.::::::::.::::::.:: :..:. ::
XP_016 GLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLIN
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB5 FAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGG
::::.:::::::::::.:::::::: : :. :. ::. : ::...:: : ::..:.::
XP_016 SAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGG
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB5 TDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQF
.::::.::::: :: ::.:::.::: ::. :::::::::::. :.:::::.:::::: .
XP_016 SDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGL
360 370 380 390 400 410
440 450 460 470 480 490
pF1KB5 REDDFRRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFA
: ::..:. :: .:... :...: : : :..:: : :. . : ::..::.::
XP_016 LEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFA
420 430 440 450 460 470
500
pF1KB5 RAFPMPGFDEH
::.::. .
XP_016 SLFPLPGLPDF
480
>>NP_004160 (OMIM: 182144) serine hydroxymethyltransfera (483 aa)
initn: 2040 init1: 1950 opt: 2033 Z-score: 2625.0 bits: 495.2 E(85289): 1.8e-139
Smith-Waterman score: 2033; 66.1% identity (85.4% similar) in 460 aa overlap (47-503:24-482)
20 30 40 50 60 70
pF1KB5 GQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIAS
. :.::: :.......:..:: :::::::
NP_004 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIAS
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 ENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGV
::: :::.::::::::::::::::::.:::::.: .::.: :::.:::.:. ::: :::
NP_004 ENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGV
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB5 NVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYK
:::::::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::
NP_004 NVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYK
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB5 LNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHIS
.:: :: :.:.:: .::::.:.::::::: :.: ..:::.:.. :: :.:.:::::::
NP_004 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB5 GLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRIN
::::: :.::::.: .::::::::::: :.:.::::::::.::::::.:: :..:. ::
NP_004 GLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLIN
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB5 FAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGG
::::.:::::::::::.:::::::: : :. :. ::. : ::...:: : ::..:.::
NP_004 SAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGG
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB5 TDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQF
.::::.::::: :: ::.:::.::: ::. :::::::::::. :.:::::.:::::: .
NP_004 SDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGL
360 370 380 390 400 410
440 450 460 470 480 490
pF1KB5 REDDFRRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFA
: ::..:. :: .:... :...: : : :..:: : :. . : ::..::.::
NP_004 LEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFA
420 430 440 450 460 470
500
pF1KB5 RAFPMPGFDEH
::.::. .
NP_004 SLFPLPGLPDF
480
>>XP_011536980 (OMIM: 138450) PREDICTED: serine hydroxym (408 aa)
initn: 2013 init1: 1987 opt: 1992 Z-score: 2573.2 bits: 485.4 E(85289): 1.4e-136
Smith-Waterman score: 1992; 92.0% identity (96.2% similar) in 339 aa overlap (166-504:73-408)
140 150 160 170 180 190
pF1KB5 VNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPY
: ..:. . :.. ::.:.. ..
XP_011 WPSTQPFCNLTTGSWGWTCPMGAISPTATCLTSSGYQPRPSSSSLCPISSTAL---AVCV
50 60 70 80 90
200 210 220 230 240 250
pF1KB5 KLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
...:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
340 350 360 370 380 390
500
pF1KB5 FPMPGFDEH
:::::::::
XP_011 FPMPGFDEH
400
>>XP_011536977 (OMIM: 138450) PREDICTED: serine hydroxym (408 aa)
initn: 2013 init1: 1987 opt: 1992 Z-score: 2573.2 bits: 485.4 E(85289): 1.4e-136
Smith-Waterman score: 1992; 92.0% identity (96.2% similar) in 339 aa overlap (166-504:73-408)
140 150 160 170 180 190
pF1KB5 VNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPY
: ..:. . :.. ::.:.. ..
XP_011 WPSTQPFCNLTTGSWGWTCPMGAISPTATCLTSSGYQPRPSSSSLCPISSTAL---AVCV
50 60 70 80 90
200 210 220 230 240 250
pF1KB5 KLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
...:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
340 350 360 370 380 390
500
pF1KB5 FPMPGFDEH
:::::::::
XP_011 FPMPGFDEH
400
>>XP_011536978 (OMIM: 138450) PREDICTED: serine hydroxym (408 aa)
initn: 2013 init1: 1987 opt: 1992 Z-score: 2573.2 bits: 485.4 E(85289): 1.4e-136
Smith-Waterman score: 1992; 92.0% identity (96.2% similar) in 339 aa overlap (166-504:73-408)
140 150 160 170 180 190
pF1KB5 VNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPY
: ..:. . :.. ::.:.. ..
XP_011 WPSTQPFCNLTTGSWGWTCPMGAISPTATCLTSSGYQPRPSSSSLCPISSTAL---AVCV
50 60 70 80 90
200 210 220 230 240 250
pF1KB5 KLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
...:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
340 350 360 370 380 390
500
pF1KB5 FPMPGFDEH
:::::::::
XP_011 FPMPGFDEH
400
504 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:32:23 2016 done: Sat Nov 5 15:32:24 2016
Total Scan time: 9.170 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]