FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5920, 532 aa 1>>>pF1KB5920 532 - 532 aa - 532 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8909+/-0.000378; mu= -2.2535+/- 0.024 mean_var=255.5186+/-53.711, 0's: 0 Z-trim(121.6): 94 B-trim: 1736 in 1/58 Lambda= 0.080235 statistics sampled from 38321 (38439) to 38321 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.451), width: 16 Scan time: 9.560 The best scores are: opt bits E(85289) NP_001025173 (OMIM: 601522) growth factor receptor ( 532) 3668 437.8 4e-122 NP_001229372 (OMIM: 601522) growth factor receptor ( 532) 3668 437.8 4e-122 NP_005301 (OMIM: 601522) growth factor receptor-bo ( 532) 3668 437.8 4e-122 NP_001229371 (OMIM: 601522) growth factor receptor ( 555) 3668 437.8 4.2e-122 XP_016880025 (OMIM: 601522) PREDICTED: growth fact ( 447) 2944 353.9 5.9e-97 NP_001317136 (OMIM: 601522) growth factor receptor ( 447) 2929 352.2 2e-96 XP_016880027 (OMIM: 601522) PREDICTED: growth fact ( 362) 2205 268.3 2.8e-71 XP_016867534 (OMIM: 601523) PREDICTED: growth fact ( 536) 1755 216.3 1.9e-55 XP_016867553 (OMIM: 601523) PREDICTED: growth fact ( 536) 1755 216.3 1.9e-55 NP_001001555 (OMIM: 601523) growth factor receptor ( 536) 1755 216.3 1.9e-55 XP_016867552 (OMIM: 601523) PREDICTED: growth fact ( 536) 1755 216.3 1.9e-55 XP_016867556 (OMIM: 601523) PREDICTED: growth fact ( 536) 1755 216.3 1.9e-55 XP_011513618 (OMIM: 601523) PREDICTED: growth fact ( 536) 1755 216.3 1.9e-55 XP_016867557 (OMIM: 601523) PREDICTED: growth fact ( 536) 1755 216.3 1.9e-55 XP_016867554 (OMIM: 601523) PREDICTED: growth fact ( 536) 1755 216.3 1.9e-55 XP_016867555 (OMIM: 601523) PREDICTED: growth fact ( 536) 1755 216.3 1.9e-55 NP_001001550 (OMIM: 601523) growth factor receptor ( 536) 1755 216.3 1.9e-55 XP_011513614 (OMIM: 601523) PREDICTED: growth fact ( 588) 1755 216.3 2e-55 XP_011513606 (OMIM: 601523) PREDICTED: growth fact ( 594) 1755 216.3 2e-55 XP_016867535 (OMIM: 601523) PREDICTED: growth fact ( 594) 1755 216.3 2e-55 NP_005302 (OMIM: 601523) growth factor receptor-bo ( 594) 1755 216.3 2e-55 XP_016867533 (OMIM: 601523) PREDICTED: growth fact ( 632) 1755 216.4 2.1e-55 XP_016867520 (OMIM: 601523) PREDICTED: growth fact ( 665) 1755 216.4 2.2e-55 XP_011513625 (OMIM: 601523) PREDICTED: growth fact ( 533) 1743 214.9 4.8e-55 XP_016867542 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867536 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867544 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867548 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867545 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867549 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867550 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867543 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867541 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867538 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867551 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867540 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867547 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867539 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867546 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867537 (OMIM: 601523) PREDICTED: growth fact ( 581) 1732 213.7 1.2e-54 XP_016867525 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867531 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867524 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867528 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867526 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867529 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867530 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867532 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867527 (OMIM: 601523) PREDICTED: growth fact ( 633) 1732 213.7 1.3e-54 XP_016867523 (OMIM: 601523) PREDICTED: growth fact ( 639) 1732 213.7 1.3e-54 >>NP_001025173 (OMIM: 601522) growth factor receptor-bou (532 aa) initn: 3668 init1: 3668 opt: 3668 Z-score: 2313.4 bits: 437.8 E(85289): 4e-122 Smith-Waterman score: 3668; 100.0% identity (100.0% similar) in 532 aa overlap (1-532:1-532) 10 20 30 40 50 60 pF1KB5 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL 490 500 510 520 530 >>NP_001229372 (OMIM: 601522) growth factor receptor-bou (532 aa) initn: 3668 init1: 3668 opt: 3668 Z-score: 2313.4 bits: 437.8 E(85289): 4e-122 Smith-Waterman score: 3668; 100.0% identity (100.0% similar) in 532 aa overlap (1-532:1-532) 10 20 30 40 50 60 pF1KB5 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL 490 500 510 520 530 >>NP_005301 (OMIM: 601522) growth factor receptor-bound (532 aa) initn: 3668 init1: 3668 opt: 3668 Z-score: 2313.4 bits: 437.8 E(85289): 4e-122 Smith-Waterman score: 3668; 100.0% identity (100.0% similar) in 532 aa overlap (1-532:1-532) 10 20 30 40 50 60 pF1KB5 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL 490 500 510 520 530 >>NP_001229371 (OMIM: 601522) growth factor receptor-bou (555 aa) initn: 3668 init1: 3668 opt: 3668 Z-score: 2313.2 bits: 437.8 E(85289): 4.2e-122 Smith-Waterman score: 3668; 100.0% identity (100.0% similar) in 532 aa overlap (1-532:24-555) 10 20 30 pF1KB5 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPE ::::::::::::::::::::::::::::::::::::: NP_001 MGKWRPGQGHTTGSVKPLSRSDAMELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 EVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRD 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 ASRPHVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRPHVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 LEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB5 DLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVAD 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB5 VNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFK 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB5 YGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALE 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB5 EAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLV 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB5 RESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRG 490 500 510 520 530 540 520 530 pF1KB5 ILPCLLRHCCTRVAL ::::::::::::::: NP_001 ILPCLLRHCCTRVAL 550 >>XP_016880025 (OMIM: 601522) PREDICTED: growth factor r (447 aa) initn: 2944 init1: 2944 opt: 2944 Z-score: 1861.6 bits: 353.9 E(85289): 5.9e-97 Smith-Waterman score: 2944; 99.8% identity (100.0% similar) in 431 aa overlap (102-532:17-447) 80 90 100 110 120 130 pF1KB5 PELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAAGATARHVCEML .::::::::::::::::::::::::::::: XP_016 MNHPLPPLKSCAIPGAQVVKVYSEDGACRSVEVAAGATARHVCEML 10 20 30 40 140 150 160 170 180 190 pF1KB5 VQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELF 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB5 KSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFC 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB5 FLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNG 170 180 190 200 210 220 320 330 340 350 360 370 pF1KB5 HKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNT 230 240 250 260 270 280 380 390 400 410 420 430 pF1KB5 LVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLW 290 300 310 320 330 340 440 450 460 470 480 490 pF1KB5 FHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRL 350 360 370 380 390 400 500 510 520 530 pF1KB5 YFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL ::::::::::::::::::::::::::::::::::::::::: XP_016 YFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL 410 420 430 440 >>NP_001317136 (OMIM: 601522) growth factor receptor-bou (447 aa) initn: 2924 init1: 2924 opt: 2929 Z-score: 1852.2 bits: 352.2 E(85289): 2e-96 Smith-Waterman score: 2929; 97.9% identity (98.2% similar) in 437 aa overlap (1-437:1-432) 10 20 30 40 50 60 pF1KB5 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY :::: : ::.: NP_001 LSAACS----W-SGRVSGTPRALSSLCATCRK 430 440 >>XP_016880027 (OMIM: 601522) PREDICTED: growth factor r (362 aa) initn: 2200 init1: 2200 opt: 2205 Z-score: 1400.6 bits: 268.3 E(85289): 2.8e-71 Smith-Waterman score: 2205; 97.0% identity (97.6% similar) in 336 aa overlap (102-437:17-347) 80 90 100 110 120 130 pF1KB5 PELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAAGATARHVCEML .::::::::::::::::::::::::::::: XP_016 MNHPLPPLKSCAIPGAQVVKVYSEDGACRSVEVAAGATARHVCEML 10 20 30 40 140 150 160 170 180 190 pF1KB5 VQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELF 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB5 KSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFC 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB5 FLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNG 170 180 190 200 210 220 320 330 340 350 360 370 pF1KB5 HKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNT 230 240 250 260 270 280 380 390 400 410 420 430 pF1KB5 LVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLW ::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 LVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAACS----W 290 300 310 320 330 340 440 450 460 470 480 490 pF1KB5 FHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRL ::.: XP_016 -SGRVSGTPRALSSLCATCRK 350 360 >>XP_016867534 (OMIM: 601523) PREDICTED: growth factor r (536 aa) initn: 1804 init1: 587 opt: 1755 Z-score: 1116.6 bits: 216.3 E(85289): 1.9e-55 Smith-Waterman score: 1908; 54.1% identity (80.2% similar) in 536 aa overlap (1-532:14-536) 10 20 30 40 pF1KB5 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLI :. : : ... : . :: . .: .: ..:.::::. : XP_016 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPR-QRVQRSQPVHI 10 20 30 40 50 50 60 70 80 90 100 pF1KB5 PTTGRKLREEER--RATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVK .. :.:.::.. :..:::.:::::::::.: : :.: :.: : : .:. . :: XP_016 LAV-RRLQEEDQQFRTSSLPAIPNPFPELCGPGSP-PVLT-PGS---LPPSQAAAKQDVK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB5 VYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVV :.::::. . ::. : ::: .:..:: ..: ..:..: ::: ::::.::: ::::: :: XP_016 VFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 EVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLN .:... ....:.:.::::.::::.::. : ..:::.::. : ... : :. .:.::::: XP_016 QVEST--MASESKFLFRKNYAKYEFFKN-PMNFFPEQMVTWCQQSN-G-SQTQLLQNFLN 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 AGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYV ..: :::::::... :.: ::... ::::::: :::::::.::::: .::...::.. XP_016 SSSCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFS 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB5 VTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKN . ::: :. ::: :.:.::::.:: : ::..:.::::.::::..::::.:::. ::.: XP_016 LIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQN 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB5 YQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKK :. :.:. : . : :.::.:.:.::::::::..::::::: :: :.::::..::::. XP_016 YRIPQQRKALLSPF-STPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKR 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB5 TNHR--LSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRN ... :. : ..::..::::: :::::::::::.:.: ::::::::::.:.:: : XP_016 STRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSN 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB5 PQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLL :..:::.::: ::.:.. ::: :..:. .::.:::.:.:.::.:::.:.:::.:.::: : XP_016 PKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKL 470 480 490 500 510 520 530 pF1KB5 RHCCTRVAL .: : :::: XP_016 KHHCIRVAL 530 >>XP_016867553 (OMIM: 601523) PREDICTED: growth factor r (536 aa) initn: 1804 init1: 587 opt: 1755 Z-score: 1116.6 bits: 216.3 E(85289): 1.9e-55 Smith-Waterman score: 1908; 54.1% identity (80.2% similar) in 536 aa overlap (1-532:14-536) 10 20 30 40 pF1KB5 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLI :. : : ... : . :: . .: .: ..:.::::. : XP_016 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPR-QRVQRSQPVHI 10 20 30 40 50 50 60 70 80 90 100 pF1KB5 PTTGRKLREEER--RATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVK .. :.:.::.. :..:::.:::::::::.: : :.: :.: : : .:. . :: XP_016 LAV-RRLQEEDQQFRTSSLPAIPNPFPELCGPGSP-PVLT-PGS---LPPSQAAAKQDVK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB5 VYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVV :.::::. . ::. : ::: .:..:: ..: ..:..: ::: ::::.::: ::::: :: XP_016 VFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 EVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLN .:... ....:.:.::::.::::.::. : ..:::.::. : ... : :. .:.::::: XP_016 QVEST--MASESKFLFRKNYAKYEFFKN-PMNFFPEQMVTWCQQSN-G-SQTQLLQNFLN 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 AGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYV ..: :::::::... :.: ::... ::::::: :::::::.::::: .::...::.. XP_016 SSSCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFS 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB5 VTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKN . ::: :. ::: :.:.::::.:: : ::..:.::::.::::..::::.:::. ::.: XP_016 LIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQN 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB5 YQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKK :. :.:. : . : :.::.:.:.::::::::..::::::: :: :.::::..::::. XP_016 YRIPQQRKALLSPF-STPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKR 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB5 TNHR--LSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRN ... :. : ..::..::::: :::::::::::.:.: ::::::::::.:.:: : XP_016 STRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSN 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB5 PQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLL :..:::.::: ::.:.. ::: :..:. .::.:::.:.:.::.:::.:.:::.:.::: : XP_016 PKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKL 470 480 490 500 510 520 530 pF1KB5 RHCCTRVAL .: : :::: XP_016 KHHCIRVAL 530 >>NP_001001555 (OMIM: 601523) growth factor receptor-bou (536 aa) initn: 1804 init1: 587 opt: 1755 Z-score: 1116.6 bits: 216.3 E(85289): 1.9e-55 Smith-Waterman score: 1908; 54.1% identity (80.2% similar) in 536 aa overlap (1-532:14-536) 10 20 30 40 pF1KB5 MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLI :. : : ... : . :: . .: .: ..:.::::. : NP_001 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPR-QRVQRSQPVHI 10 20 30 40 50 50 60 70 80 90 100 pF1KB5 PTTGRKLREEER--RATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVK .. :.:.::.. :..:::.:::::::::.: : :.: :.: : : .:. . :: NP_001 LAV-RRLQEEDQQFRTSSLPAIPNPFPELCGPGSP-PVLT-PGS---LPPSQAAAKQDVK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB5 VYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVV :.::::. . ::. : ::: .:..:: ..: ..:..: ::: ::::.::: ::::: :: NP_001 VFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 EVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLN .:... ....:.:.::::.::::.::. : ..:::.::. : ... : :. .:.::::: NP_001 QVEST--MASESKFLFRKNYAKYEFFKN-PMNFFPEQMVTWCQQSN-G-SQTQLLQNFLN 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 AGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYV ..: :::::::... :.: ::... ::::::: :::::::.::::: .::...::.. NP_001 SSSCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFS 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB5 VTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKN . ::: :. ::: :.:.::::.:: : ::..:.::::.::::..::::.:::. ::.: NP_001 LIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQN 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB5 YQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKK :. :.:. : . : :.::.:.:.::::::::..::::::: :: :.::::..::::. NP_001 YRIPQQRKALLSPF-STPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKR 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB5 TNHR--LSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRN ... :. : ..::..::::: :::::::::::.:.: ::::::::::.:.:: : NP_001 STRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSN 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB5 PQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLL :..:::.::: ::.:.. ::: :..:. .::.:::.:.:.::.:::.:.:::.:.::: : NP_001 PKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKL 470 480 490 500 510 520 530 pF1KB5 RHCCTRVAL .: : :::: NP_001 KHHCIRVAL 530 532 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:41:33 2016 done: Sat Nov 5 10:41:34 2016 Total Scan time: 9.560 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]