FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5923, 505 aa 1>>>pF1KB5923 505 - 505 aa - 505 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0799+/-0.000832; mu= 2.4902+/- 0.050 mean_var=211.1751+/-42.789, 0's: 0 Z-trim(115.2): 5 B-trim: 7 in 1/51 Lambda= 0.088258 statistics sampled from 15789 (15792) to 15789 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.485), width: 16 Scan time: 3.880 The best scores are: opt bits E(32554) CCDS855.2 PPM1J gene_id:333926|Hs108|chr1 ( 505) 3463 453.3 3e-127 CCDS44934.1 PPM1H gene_id:57460|Hs108|chr12 ( 514) 1303 178.2 1.9e-44 CCDS46840.1 PPM1M gene_id:132160|Hs108|chr3 ( 247) 831 117.9 1.3e-26 >>CCDS855.2 PPM1J gene_id:333926|Hs108|chr1 (505 aa) initn: 3463 init1: 3463 opt: 3463 Z-score: 2398.1 bits: 453.3 E(32554): 3e-127 Smith-Waterman score: 3463; 99.8% identity (100.0% similar) in 505 aa overlap (1-505:1-505) 10 20 30 40 50 60 pF1KB5 MLNRVRSAVAHLVSSGGAPPPRPKSPDLPNAASAPPAAAPEAPRSPPAKAGSGSATPAKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 MLNRVRSAVAHLVSSGGAPPPRPKSPDLPNAASAPPAAAPEAPRSPPAKAGSGSATPAKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VEARASFSRPTFLQLSPGGLRRADDHAGRAVQSPPDTGRRLPWSTGYAEVINAGKSRHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 VEARASFSRPTFLQLSPGGLRRADDHAGRAVQSPPDTGRRLPWSTGYAEVINAGKSRHNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DQACCEVVYVEGRRSVTGVPREPSRGQGLCFYYWGLFDGHAGGGAAEMASRLLHRHIREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 DQACCEVVYVEGRRSVTGVPREPSRGQGLCFYYWGLFDGHAGGGAAEMASRLLHRHIREQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LKDLVEILQDPSPPPLCLPTTPGTPDSSDPSHLLGPQSCWSSQKEVSHESLVVGAIENAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: CCDS85 LKDLVEILQDPSPPPLCLPTTPGTPDSSDPSHLLGPQSCWSSQKEVSHESLVVGAVENAF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 QLMDEQMARERRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 QLMDEQMARERRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 TERQRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 TERQRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FPLVCGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 FPLVCGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRYTALAQALVLGARGTPRDRGWRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 DVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRYTALAQALVLGARGTPRDRGWRL 430 440 450 460 470 480 490 500 pF1KB5 PNNKLGSGDDISVFVIPLGGPGSYS ::::::::::::::::::::::::: CCDS85 PNNKLGSGDDISVFVIPLGGPGSYS 490 500 >>CCDS44934.1 PPM1H gene_id:57460|Hs108|chr12 (514 aa) initn: 1699 init1: 1289 opt: 1303 Z-score: 911.6 bits: 178.2 E(32554): 1.9e-44 Smith-Waterman score: 1694; 55.7% identity (74.5% similar) in 490 aa overlap (45-498:20-507) 20 30 40 50 60 70 pF1KB5 SGGAPPPRPKSPDLPNAASAPPAAAPEAPRSPPAKAGSGSATPAKAVEARASFSRPTFLQ : .. :.:: .. . : ..:: :: CCDS44 MLTRVKSAVANFMGGIMAGSSGSEHGGGSCG-GSDLPLRFPYGRPEFLG 10 20 30 40 80 90 100 110 120 130 pF1KB5 LSPGGLRRADDHAGRAVQSPPDTGRRLPWSTGYAEVINAGKSRHNEDQACCEVVYVEGRR :: .. . :: .: . .: :::::.:::::::::::: :::::: :::. :. . CCDS44 LSQDEVECSADHIARPILILKET-RRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKA 50 60 70 80 90 100 140 150 160 170 pF1KB5 -SVTGVP-------------------REPSRGQGLCFYYWGLFDGHAGGGAAEMASRLLH .::..: .: :...:. .::.:::::::.::: .:::::. CCDS44 GAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQ 110 120 130 140 150 160 180 190 200 210 pF1KB5 RHIREQLKDLVEILQDPSP-PPLCLPTTP-GTPDSSD--------------PSHLLGPQS .:: :::.:.:.::.. . :: :: : .:: .: :. : . CCDS44 HHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPT 170 180 190 200 210 220 220 230 240 250 260 270 pF1KB5 CWSSQKEVSHESLVVGAIENAFQLMDEQMARERRGHQVEGGCCALVVIYLLGKVYVANAG . ..:.. :: ::.::.:.::. :: :. ::: .... ::: ::.:: ::::.:::::: CCDS44 RFFTEKKIPHECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAG 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB5 DSRAIIVRNGEIIPMSREFTPETERQRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQR ::::::.::::::::: :::::::::::: :.:..:.:::.::::::::::: ::::.. CCDS44 DSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKK 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB5 MLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIK ::::: :::::::: :: :::.:::. :::::::::::::::::::::.::: .:.. :: CCDS44 MLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIK 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB5 PFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRY :::: ::::.:::..:.: ::::.:.::::::: .. ::: .. . : .:.: :: CCDS44 PFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRY 410 420 430 440 450 460 460 470 480 490 500 pF1KB5 TALAQALVLGARGTPRDRGWRLPNNKLGSGDDISVFVIPLGGPGSYS : :: ::. :::. .:::::. :..:::::::::.:::: CCDS44 TLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS 470 480 490 500 510 >>CCDS46840.1 PPM1M gene_id:132160|Hs108|chr3 (247 aa) initn: 810 init1: 753 opt: 831 Z-score: 591.3 bits: 117.9 E(32554): 1.3e-26 Smith-Waterman score: 831; 51.2% identity (77.4% similar) in 248 aa overlap (258-505:2-244) 230 240 250 260 270 280 pF1KB5 HESLVVGAIENAFQLMDEQMARERRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRN ::: :::.. : ::.:.:::::::::.:: CCDS46 MGGCTALVAVSLQGKLYMANAGDSRAILVRR 10 20 30 290 300 310 320 330 340 pF1KB5 GEIIPMSREFTPETERQRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQRMLYRDQNMT :: :.: ::::::::::.: :.:. ::::..:::.::::::. .:::..:.::..:. CCDS46 DEIRPLSFEFTPETERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMS 40 50 60 70 80 90 350 360 370 380 390 400 pF1KB5 GWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEV ::.::..: ::..::. :.:..::...:..:.::::::.:.: .... .:::: :.: CCDS46 GWSYKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQV 100 110 120 130 140 150 410 420 430 440 450 460 pF1KB5 RVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRYTALAQALVL : :. : : :::.:..::::::: .. .:: : : . . . : :.. ::: :. CCDS46 TVLDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDPH-RFSKLAQMLIH 160 170 180 190 200 210 470 480 490 500 pF1KB5 GARGTPRDRGWRLPNNKLGSGDDISVFVIPLGGPGSYS ...: .: : .. : ::.::::::: . :. : CCDS46 STQGK-EDS---LTEEGQVSYDDVSVFVIPLHSQGQESSDH 220 230 240 505 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:35:23 2016 done: Sat Nov 5 15:35:23 2016 Total Scan time: 3.880 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]