FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5925, 504 aa 1>>>pF1KB5925 504 - 504 aa - 504 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9237+/-0.000348; mu= -1.4764+/- 0.022 mean_var=302.6728+/-61.617, 0's: 0 Z-trim(123.9): 46 B-trim: 745 in 1/56 Lambda= 0.073720 statistics sampled from 44615 (44668) to 44615 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.524), width: 16 Scan time: 11.420 The best scores are: opt bits E(85289) XP_011514463 (OMIM: 607218,612245,612251) PREDICTE ( 504) 3577 393.7 6.4e-109 NP_116032 (OMIM: 607218,612245,612251) interferon ( 498) 3428 377.9 3.7e-104 NP_001092100 (OMIM: 607218,612245,612251) interfer ( 498) 3428 377.9 3.7e-104 NP_001092097 (OMIM: 607218,612245,612251) interfer ( 498) 3428 377.9 3.7e-104 XP_011514466 (OMIM: 607218,612245,612251) PREDICTE ( 488) 2332 261.3 4.5e-69 XP_011514465 (OMIM: 607218,612245,612251) PREDICTE ( 488) 2332 261.3 4.5e-69 XP_011514464 (OMIM: 607218,612245,612251) PREDICTE ( 488) 2332 261.3 4.5e-69 NP_001092099 (OMIM: 607218,612245,612251) interfer ( 514) 2299 257.8 5.4e-68 XP_011514462 (OMIM: 607218,612245,612251) PREDICTE ( 514) 2299 257.8 5.4e-68 XP_006716037 (OMIM: 607218,612245,612251) PREDICTE ( 514) 2299 257.8 5.4e-68 XP_011514460 (OMIM: 607218,612245,612251) PREDICTE ( 514) 2299 257.8 5.4e-68 XP_011514461 (OMIM: 607218,612245,612251) PREDICTE ( 514) 2299 257.8 5.4e-68 XP_005250374 (OMIM: 607218,612245,612251) PREDICTE ( 514) 2299 257.8 5.4e-68 NP_001229381 (OMIM: 607218,612245,612251) interfer ( 412) 1769 201.4 4.2e-51 NP_001193625 (OMIM: 119300,119500,607199,608864) i ( 372) 1016 121.2 5.1e-27 NP_006138 (OMIM: 119300,119500,607199,608864) inte ( 467) 597 76.8 1.6e-13 XP_005252966 (OMIM: 605047,616345) PREDICTED: inte ( 487) 588 75.8 3.1e-13 NP_004020 (OMIM: 605047,616345) interferon regulat ( 474) 587 75.7 3.3e-13 NP_002190 (OMIM: 147576) interferon regulatory fac ( 349) 398 55.5 2.9e-07 NP_001184053 (OMIM: 603734,616532) interferon regu ( 300) 388 54.4 5.5e-07 XP_016878688 (OMIM: 601565,614893,614894) PREDICTE ( 222) 384 53.8 5.9e-07 NP_001562 (OMIM: 603734,616532) interferon regulat ( 427) 388 54.5 7.1e-07 XP_016882256 (OMIM: 603734,616532) PREDICTED: inte ( 427) 388 54.5 7.1e-07 XP_016882255 (OMIM: 603734,616532) PREDICTED: inte ( 427) 388 54.5 7.1e-07 NP_001184051 (OMIM: 603734,616532) interferon regu ( 452) 388 54.5 7.4e-07 XP_006723260 (OMIM: 603734,616532) PREDICTED: inte ( 452) 388 54.5 7.4e-07 XP_006723261 (OMIM: 603734,616532) PREDICTED: inte ( 452) 388 54.5 7.4e-07 NP_002154 (OMIM: 601565,614893,614894) interferon ( 426) 387 54.4 7.7e-07 XP_006715153 (OMIM: 601900,611724) PREDICTED: inte ( 415) 384 54.1 9.4e-07 NP_002451 (OMIM: 601900,611724) interferon regulat ( 451) 384 54.1 1e-06 XP_011541680 (OMIM: 147575,211980,613659) PREDICTE ( 284) 377 53.2 1.2e-06 NP_002189 (OMIM: 147575,211980,613659) interferon ( 325) 377 53.2 1.3e-06 NP_001182215 (OMIM: 601900,611724) interferon regu ( 450) 380 53.7 1.3e-06 XP_011518368 (OMIM: 605047,616345) PREDICTED: inte ( 502) 381 53.8 1.3e-06 NP_001563 (OMIM: 605047,616345) interferon regulat ( 503) 381 53.8 1.3e-06 XP_005252964 (OMIM: 605047,616345) PREDICTED: inte ( 515) 381 53.8 1.4e-06 XP_005252963 (OMIM: 605047,616345) PREDICTED: inte ( 516) 381 53.8 1.4e-06 NP_004022 (OMIM: 605047,616345) interferon regulat ( 516) 381 53.8 1.4e-06 NP_006075 (OMIM: 147574) interferon regulatory fac ( 393) 369 52.5 2.7e-06 NP_001184054 (OMIM: 603734,616532) interferon regu ( 281) 336 48.8 2.4e-05 NP_001184055 (OMIM: 603734,616532) interferon regu ( 281) 336 48.8 2.4e-05 XP_016873163 (OMIM: 605047,616345) PREDICTED: inte ( 210) 330 48.1 3.1e-05 >>XP_011514463 (OMIM: 607218,612245,612251) PREDICTED: i (504 aa) initn: 3577 init1: 3577 opt: 3577 Z-score: 2076.4 bits: 393.7 E(85289): 6.4e-109 Smith-Waterman score: 3577; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV 430 440 450 460 470 480 490 500 pF1KB5 AQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::: XP_011 AQAPPGAGLGVGQGPWPMHPAGMQ 490 500 >>NP_116032 (OMIM: 607218,612245,612251) interferon regu (498 aa) initn: 2279 init1: 2279 opt: 3428 Z-score: 1990.9 bits: 377.9 E(85289): 3.7e-104 Smith-Waterman score: 3428; 96.6% identity (97.4% similar) in 504 aa overlap (1-504:1-498) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK ::::::::::::::::::::::::::::::::::::::::. :. : . : .: NP_116 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLR----- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 -PPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV 420 430 440 450 460 470 490 500 pF1KB5 AQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::: NP_116 AQAPPGAGLGVGQGPWPMHPAGMQ 480 490 >>NP_001092100 (OMIM: 607218,612245,612251) interferon r (498 aa) initn: 2279 init1: 2279 opt: 3428 Z-score: 1990.9 bits: 377.9 E(85289): 3.7e-104 Smith-Waterman score: 3428; 96.6% identity (97.4% similar) in 504 aa overlap (1-504:1-498) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK ::::::::::::::::::::::::::::::::::::::::. :. : . : .: NP_001 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLR----- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -PPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV 420 430 440 450 460 470 490 500 pF1KB5 AQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::: NP_001 AQAPPGAGLGVGQGPWPMHPAGMQ 480 490 >>NP_001092097 (OMIM: 607218,612245,612251) interferon r (498 aa) initn: 2279 init1: 2279 opt: 3428 Z-score: 1990.9 bits: 377.9 E(85289): 3.7e-104 Smith-Waterman score: 3428; 96.6% identity (97.4% similar) in 504 aa overlap (1-504:1-498) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK ::::::::::::::::::::::::::::::::::::::::. :. : . : .: NP_001 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLR----- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -PPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV 420 430 440 450 460 470 490 500 pF1KB5 AQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::: NP_001 AQAPPGAGLGVGQGPWPMHPAGMQ 480 490 >>XP_011514466 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa) initn: 2323 init1: 2323 opt: 2332 Z-score: 1361.0 bits: 261.3 E(85289): 4.5e-69 Smith-Waterman score: 3426; 96.8% identity (96.8% similar) in 504 aa overlap (1-504:1-488) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK :::::::::::::::::::::::::::::::::::::::: :::: XP_011 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLT----------------EDVK 130 140 150 160 190 200 210 220 230 240 pF1KB5 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV 410 420 430 440 450 460 490 500 pF1KB5 AQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::: XP_011 AQAPPGAGLGVGQGPWPMHPAGMQ 470 480 >>XP_011514465 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa) initn: 2323 init1: 2323 opt: 2332 Z-score: 1361.0 bits: 261.3 E(85289): 4.5e-69 Smith-Waterman score: 3426; 96.8% identity (96.8% similar) in 504 aa overlap (1-504:1-488) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK :::::::::::::::::::::::::::::::::::::::: :::: XP_011 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLT----------------EDVK 130 140 150 160 190 200 210 220 230 240 pF1KB5 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV 410 420 430 440 450 460 490 500 pF1KB5 AQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::: XP_011 AQAPPGAGLGVGQGPWPMHPAGMQ 470 480 >>XP_011514464 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa) initn: 2323 init1: 2323 opt: 2332 Z-score: 1361.0 bits: 261.3 E(85289): 4.5e-69 Smith-Waterman score: 3426; 96.8% identity (96.8% similar) in 504 aa overlap (1-504:1-488) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK :::::::::::::::::::::::::::::::::::::::: :::: XP_011 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLT----------------EDVK 130 140 150 160 190 200 210 220 230 240 pF1KB5 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAH 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPV 410 420 430 440 450 460 490 500 pF1KB5 AQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::: XP_011 AQAPPGAGLGVGQGPWPMHPAGMQ 470 480 >>NP_001092099 (OMIM: 607218,612245,612251) interferon r (514 aa) initn: 2279 init1: 2279 opt: 2299 Z-score: 1341.7 bits: 257.8 E(85289): 5.4e-68 Smith-Waterman score: 3547; 98.1% identity (98.1% similar) in 514 aa overlap (1-504:1-514) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 WPPTLQPPTL----------QPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLP :::::::::: :::::::::::::::::::::::::::::::::::::::: NP_001 WPPTLQPPTLRPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 ASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 QVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 FWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 DRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHI 430 440 450 460 470 480 480 490 500 pF1KB5 WQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::::::::::::: NP_001 WQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ 490 500 510 >>XP_011514462 (OMIM: 607218,612245,612251) PREDICTED: i (514 aa) initn: 2279 init1: 2279 opt: 2299 Z-score: 1341.7 bits: 257.8 E(85289): 5.4e-68 Smith-Waterman score: 3547; 98.1% identity (98.1% similar) in 514 aa overlap (1-504:1-514) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 WPPTLQPPTL----------QPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLP :::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 WPPTLQPPTLRPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 ASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 QVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 FWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 DRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHI 430 440 450 460 470 480 480 490 500 pF1KB5 WQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::::::::::::: XP_011 WQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ 490 500 510 >>XP_006716037 (OMIM: 607218,612245,612251) PREDICTED: i (514 aa) initn: 2279 init1: 2279 opt: 2299 Z-score: 1341.7 bits: 257.8 E(85289): 5.4e-68 Smith-Waterman score: 3547; 98.1% identity (98.1% similar) in 514 aa overlap (1-504:1-514) 10 20 30 40 50 60 pF1KB5 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVK 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 WPPTLQPPTL----------QPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLP :::::::::: :::::::::::::::::::::::::::::::::::::::: XP_006 WPPTLQPPTLRPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 ASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 QVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 FWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 DRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHI 430 440 450 460 470 480 480 490 500 pF1KB5 WQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ :::::::::::::::::::::::::::::::::: XP_006 WQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ 490 500 510 504 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:42:11 2016 done: Sat Nov 5 10:42:12 2016 Total Scan time: 11.420 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]