FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5930, 538 aa 1>>>pF1KB5930 538 - 538 aa - 538 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0564+/-0.000698; mu= 10.7157+/- 0.042 mean_var=114.8613+/-23.521, 0's: 0 Z-trim(113.5): 35 B-trim: 215 in 2/51 Lambda= 0.119671 statistics sampled from 14094 (14125) to 14094 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.434), width: 16 Scan time: 3.450 The best scores are: opt bits E(32554) CCDS10630.1 IL21R gene_id:50615|Hs108|chr16 ( 538) 3838 673.3 2e-193 CCDS13942.1 IL2RB gene_id:3560|Hs108|chr22 ( 551) 324 66.6 8.5e-11 >>CCDS10630.1 IL21R gene_id:50615|Hs108|chr16 (538 aa) initn: 3838 init1: 3838 opt: 3838 Z-score: 3586.2 bits: 673.3 E(32554): 2e-193 Smith-Waterman score: 3838; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538) 10 20 30 40 50 60 pF1KB5 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 490 500 510 520 530 >>CCDS13942.1 IL2RB gene_id:3560|Hs108|chr22 (551 aa) initn: 245 init1: 120 opt: 324 Z-score: 307.3 bits: 66.6 E(32554): 8.5e-11 Smith-Waterman score: 357; 25.1% identity (50.6% similar) in 514 aa overlap (5-471:8-478) 10 20 30 40 pF1KB5 MPRGWAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWN----LHPS : :::.::: .: : ...:. . .. :. :. :. . CCDS13 MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WSQDGALQDT 10 20 30 40 50 50 60 70 80 90 pF1KB5 TLTL-TWQDQYEELKDEATSCSLHRSAHNATHATYTCHM-----DVFHFMADDIFSVNIT . . .: :. . .: : ...:...:.. : .. . :: .. . CCDS13 SCQVHAWPDR----RRWNQTCELL----PVSQASWACNLILGAPDSQKLTTVDIVTLRVL 60 70 80 90 100 100 110 120 130 140 150 pF1KB5 DQSGNY--SQECGSFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQ . : . .: :... :... :. . . ::::. . : .... .:. CCDS13 CREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLE 110 120 130 140 150 160 160 170 180 190 200 210 pF1KB5 YELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWS .: . . : : .: :... ... . . :..::.:::. :. : ::: CCDS13 FEARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWS 170 180 190 200 210 220 220 230 240 250 260 pF1KB5 EWSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSL----KTHPLWRLWKKIW ::.:. :.:. : . : :::. : .. :: . : .: : : ::. CCDS13 PWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGP-W--LKKVL 230 240 250 260 270 270 280 290 300 310 320 pF1KB5 A--VPSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPA .:.: .:: : . .:: .::...:: .::. : .::. : ::: CCDS13 KCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEVL--------- 280 290 300 310 320 330 340 350 360 370 380 pF1KB5 KRLQLTELQEPAELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSI-DTVTVLDAE .: ..:.: :...: ::.:. . .:. : : .. : . . :.. . . CCDS13 ERDKVTQL-----LLQQDKVPEPA----SLSSNHSLTSCFTNQGYFFFHLPDALEIEACQ 330 340 350 360 370 390 400 410 420 430 pF1KB5 GPCTW-PCSCEDD-----GYPALDLDAGLEPSPGLED-----PLLDAGTTVLSCGCVSAG :. : : :: : :. . :.: : .: : : ..: . ... CCDS13 VYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRD-DLLLFSPSLLGGP 380 390 400 410 420 430 440 450 460 470 480 490 pF1KB5 SPGLGGPLGSLL--DRLKPPLAD--GEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTF :: .: :: .:. : : . .:: : : .:: CCDS13 SPPSTAPGGSGAGEERMPPSLQERVPRDW-DPQPLGPPTPGVPDLVDFQPPPELVLREAG 440 450 460 470 480 490 500 510 520 530 pF1KB5 DSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS CCDS13 EEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV 500 510 520 530 540 550 538 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:37:23 2016 done: Sat Nov 5 15:37:23 2016 Total Scan time: 3.450 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]