FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5939, 508 aa 1>>>pF1KB5939 508 - 508 aa - 508 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2149+/-0.000917; mu= 13.8411+/- 0.056 mean_var=87.7611+/-17.152, 0's: 0 Z-trim(106.8): 41 B-trim: 0 in 0/52 Lambda= 0.136906 statistics sampled from 9166 (9206) to 9166 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.283), width: 16 Scan time: 3.340 The best scores are: opt bits E(32554) CCDS11787.1 P4HB gene_id:5034|Hs108|chr17 ( 508) 3358 673.5 1.5e-193 CCDS42089.1 PDIA2 gene_id:64714|Hs108|chr16 ( 525) 1571 320.6 2.8e-87 CCDS10584.1 PDILT gene_id:204474|Hs108|chr16 ( 584) 951 198.1 2.2e-50 CCDS5893.1 PDIA4 gene_id:9601|Hs108|chr7 ( 645) 907 189.4 1e-47 CCDS10101.1 PDIA3 gene_id:2923|Hs108|chr15 ( 505) 643 137.3 4e-32 CCDS8670.1 ERP27 gene_id:121506|Hs108|chr12 ( 273) 426 94.3 1.9e-19 CCDS35082.1 ERP44 gene_id:23071|Hs108|chr9 ( 406) 329 75.2 1.6e-13 CCDS32840.1 TMX3 gene_id:54495|Hs108|chr18 ( 454) 320 73.4 5.9e-13 >>CCDS11787.1 P4HB gene_id:5034|Hs108|chr17 (508 aa) initn: 3358 init1: 3358 opt: 3358 Z-score: 3588.2 bits: 673.5 E(32554): 1.5e-193 Smith-Waterman score: 3358; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508) 10 20 30 40 50 60 pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD 430 440 450 460 470 480 490 500 pF1KB5 DDDLEDLEEAEEPDMEEDDDQKAVKDEL :::::::::::::::::::::::::::: CCDS11 DDDLEDLEEAEEPDMEEDDDQKAVKDEL 490 500 >>CCDS42089.1 PDIA2 gene_id:64714|Hs108|chr16 (525 aa) initn: 1561 init1: 752 opt: 1571 Z-score: 1680.5 bits: 320.6 E(32554): 2.8e-87 Smith-Waterman score: 1571; 50.0% identity (76.5% similar) in 468 aa overlap (18-474:32-495) 10 20 30 40 pF1KB5 MLRRALLCLAVAALVRADAPEEE----DHVLVLRKSNFAEALAAHKY . :::: : .::: . ... :: : CCDS42 SRQLLPVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIK :::::::::::::.::::::.:::. : ::. . :::::. . .::...:: :::.: CCDS42 LLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLK 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB5 FFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKD :::::. . :.:::. :.:. :..::..:.::.: : : :::..:. . ...:::::.: CCDS42 FFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQD 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 VESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKE ...... :: :. :. ::.:. .:... : :: ::::::::::: .: : .: CCDS42 LQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLTKDTVVLFKKFDEGRADFP--VDEE 190 200 210 220 230 230 240 250 260 270 pF1KB5 NLLD------FIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKT :: :. ... :: ::. ::. :::...: .:.:::. .... . :..: CCDS42 LGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGE 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB5 AAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKP-ESEELTA :: :.:..::. .: .::...:..:::: : :..::..:: :: : .. .:: CCDS42 AAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPTLRLVNLETT-KKYAPVDGGPVTA 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB5 ERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPW :: ::: :.:..::.:.:::.: :::..:::.:::::::.::::: :::::.::::: CCDS42 ASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPW 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB5 CGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVID : :::..:: :. :.: :.:::.:.::..:.::::..: ::.:::::.:::. : ::. CCDS42 CTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIE 420 430 440 450 460 470 460 470 480 490 500 pF1KB5 YNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL :.. : :. :.:::..:: CCDS42 YKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL 480 490 500 510 520 >>CCDS10584.1 PDILT gene_id:204474|Hs108|chr16 (584 aa) initn: 864 init1: 389 opt: 951 Z-score: 1018.0 bits: 198.1 E(32554): 2.2e-50 Smith-Waterman score: 951; 32.6% identity (67.4% similar) in 485 aa overlap (22-504:41-523) 10 20 30 40 50 pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAP :: .::: ..... : ..:.: :. : CCDS10 VAACVSAVHSSPEVNAGVSSIHITKPVHILEERSLLVLTPAGLTQMLNQTRFLMVLFHNP 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB5 WCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTA . . :: : .::. . . : ..::: : :..: :..:. : .:.: .:. . CCDS10 SSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKAPELKLFFEGNRS 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB5 SPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQ : . :. .: ::... . : . .. . .: : ....:::.:.: . :. CCDS10 EPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFVISRPLVIVGFFQDLEEEVAEL 140 150 160 170 180 190 180 190 200 210 220 pF1KB5 FLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFD-EGRNNFEGEVT-KENLLDFI : .. . . .. ::. . ..:...... :.:..::: .:... .. : :..: : CCDS10 FYDVIKDFPELTFGVITIGNVIGRFHVTLDSVLVFKKGKIVNRQKLINDSTNKQELNRVI 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB5 KHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFI :.. .:::.. .. : .: .:.:::. :: .: ....: :.. :..::::: CCDS10 KQHLTDFVIEYNTENKDLISELHIMSHMLLFVSKSSESYGIIIQHYKLASKEFQNKILFI 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB5 FIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEG ..:.:. : :....: . . . :.:....: . ..:: :...: : . .: . :: CCDS10 LVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSD-ARYKMPSDDITYESLKKFGRSFLSK 320 330 340 350 360 350 360 370 380 390 400 pF1KB5 KIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDK . : :.:.:. ::. :: ::::::. :.::..:.::: ::::: .::.: :. .. CCDS10 NATKHQSSEEIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEE 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB5 LGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF ::. :..: .:.:::.: :::... . . .: ...::......:. :.::.:: ::. : CCDS10 LGRKYQNHSTIIIAKIDVTANDIQLMYLDRYPFFRLFPSGSQQAVL-YKGEHTLKGFSDF 430 440 450 460 470 480 470 480 490 500 pF1KB5 LESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL ::: . :.:.: ..:. : . : ..: : CCDS10 LESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKL 490 500 510 520 530 540 CCDS10 EEPAGKKKTSEEVVVVVAKPKGPPVQKKKPKVKEEL 550 560 570 580 >>CCDS5893.1 PDIA4 gene_id:9601|Hs108|chr7 (645 aa) initn: 718 init1: 333 opt: 907 Z-score: 970.3 bits: 189.4 E(32554): 1e-47 Smith-Waterman score: 907; 36.8% identity (65.4% similar) in 468 aa overlap (27-471:180-632) 10 20 30 40 50 pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHC ::: : :: :.. .:::::::::::: CCDS58 DYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHC 150 160 170 180 190 200 60 70 80 90 100 110 pF1KB5 KALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEY : ::::: ::: .:. .. : ::::::: :.:::... : ::::.:.::.: : .: CCDS58 KKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKG---RPYDY 210 220 230 240 250 260 120 130 140 150 160 170 pF1KB5 TAGREADDIVNWLKKRTGPAATT-LPDGAAAESLVESSEVAVIGFFKDVESDSA-KQFLQ .. :: ::... ...:: . : . : : ....: .:: :: ::: : .:. . CCDS58 NGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKG-ESDPAYQQYQD 270 280 290 300 310 320 180 190 200 210 220 pF1KB5 AAEAI-DDIPFGITSNSDVFSKYQLDKDGVVLFK--KFD---EGRNNF---EGEVTKENL ::. . .: : : .... . .... .:... ::. : :... .: . . CCDS58 AANNLREDYKFHHTFSTEIAKFLKVSQGQLVVMQPEKFQSKYEPRSHMMDVQGSTQDSAI 330 340 350 360 370 380 230 240 250 260 270 280 pF1KB5 LDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLS-NFKTAAESFKG ::. . :::: . . ... : . : : :. .: ....:.. ... CCDS58 KDFVLKYALPLV-------GHRKVSNDAKRYTRR--PLVVVYYSVDFSFDYRAATQFWRS 390 400 410 420 430 290 300 310 320 330 pF1KB5 KIL--------FIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTA :.: . : .:. : .. .::. : : :.: :. : ::. . CCDS58 KVLEVAKDFPEYTFAIADEEDYAGEVKDLGLS-ESGEDVNAAILDESGKKFAMEPEEFDS 440 450 460 470 480 490 340 350 360 370 380 390 pF1KB5 ERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPW . . :: : .::.:: . :: .:.. .: ::::.:::.:.....: ::.:..:::::: CCDS58 DTLREFVTAFKKGKLKPVIKSQPVPKN-NKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPW 500 510 520 530 540 550 400 410 420 430 440 450 pF1KB5 CGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA--VKVHSFPTLKFFPASADRTV ::::::: :....:.. :: ....::::::.:::.: . ::..:::. : :.. .. CCDS58 CGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNP 560 570 580 590 600 610 460 470 480 490 500 pF1KB5 IDYNG-ERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL . ..: .: :. ..::.: CCDS58 VKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 620 630 640 >-- initn: 300 init1: 300 opt: 328 Z-score: 352.3 bits: 75.1 E(32554): 2.7e-13 Smith-Waterman score: 328; 43.4% identity (70.5% similar) in 122 aa overlap (21-142:59-177) 10 20 30 40 50 pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYA .::. :::: .:: . .: . .:.:::: CCDS58 EDSSNRENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDTVLLEFYA 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB5 PWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDT ::::::: .:::: : :. :: . : .::.::: : ::... : ::::::....:.. CCDS58 PWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQA 90 100 110 120 130 140 120 130 140 150 160 170 pF1KB5 ASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAK . .: ..: ..:: ... . : : :. CCDS58 V---DYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPW 150 160 170 180 190 200 180 190 200 210 220 230 pF1KB5 QFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIK CCDS58 CGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYD 210 220 230 240 250 260 >>CCDS10101.1 PDIA3 gene_id:2923|Hs108|chr15 (505 aa) initn: 675 init1: 280 opt: 643 Z-score: 690.2 bits: 137.3 E(32554): 4e-32 Smith-Waterman score: 853; 34.7% identity (63.5% similar) in 498 aa overlap (2-471:3-481) 10 20 30 40 50 pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA---AHKYLLVEFYAPWCGHC ::: : .:: :. : . :: : .:: .. . .::::.::::::: CCDS10 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 KALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEY : ::::: :: .::. . ::::: : ... ..::: ::::.:.::.:. :. : CCDS10 KRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AY 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 TAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAA . : :: ::. :::..:::.. : .... .......::: : :.. ..::.:: CCDS10 DGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAA 120 130 140 150 160 170 180 190 200 210 220 pF1KB5 EAI-DDIPFGITSNSDVFSKYQLDKDGVVLFK------KFDEGRNNF-EGEVTKENLLDF . :. :. :. .. ..:. . .:..::. ::.. . : ..:. .. : CCDS10 SNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYD--GKLSNFKTAAESFKGKI :..: . . ..::.. : : . ::. .: ::. .: ::. ..... CCDS10 IQENIFGICPHMTEDNKDLIQGKD-----LLIAYYDV-DYEKNAKGSNY------WRNRV 240 250 260 270 280 290 300 310 320 330 pF1KB5 LFI---FIDSDHTDNQRI---------LEFFGLKKE--ECPAVRLITLEEEMTKYKPESE ... :.:. : : . : :::.. : :.: . : . : .. : CCDS10 MMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFS 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB5 ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF . .. . .: . ...:..: .: :. .::. : ::::.:..::.... .:.:.:..:: CCDS10 R-DGKALERFLQDYFDGNLKRYLKSEPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEF 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB5 YAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASAD :::::::::.: : . .::: . ::::::::.:::.: . .:..:::. : ::. CCDS10 YAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKK 410 420 430 440 450 460 460 470 480 490 500 pF1KB5 RTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL . :.: : :. : ..:. CCDS10 LNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL 470 480 490 500 >>CCDS8670.1 ERP27 gene_id:121506|Hs108|chr12 (273 aa) initn: 318 init1: 156 opt: 426 Z-score: 462.6 bits: 94.3 E(32554): 1.9e-19 Smith-Waterman score: 426; 32.5% identity (65.4% similar) in 231 aa overlap (130-351:29-257) 100 110 120 130 140 150 pF1KB5 PTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLP----DGAAAESLVESSEV :. ::.:. : : :: .. ..:: CCDS86 MEAAPSRFMFLLFLLTCELAAEVAAEVEKSSDGPGAAQEPTWLTDVPAAMEFIAATEV 10 20 30 40 50 160 170 180 190 200 210 pF1KB5 AVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNN ::::::.:.: .. . . .. . . :::...:.:...:.. . . ::. :. . : CCDS86 AVIGFFQDLEIPAVPILHSMVQKFPGVSFGISTDSEVLTHYNITGNTICLFRLVDNEQLN 60 70 80 90 100 110 220 230 240 250 260 270 pF1KB5 FEGE----VTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGK .: : . .: ::. :.: .: :.. :. .:.. :. :.::.. :. .:. . CCDS86 LEDEDIESIDATKLSRFIEINSLHMVTEYNPVTVIGLFNSVIQIHLLLIMNKASPEYEEN 120 130 140 150 160 170 280 290 300 310 320 330 pF1KB5 LSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLI-TLEEEMTKYKPE . .. ::. :.::::::..:: .: ... :: ::. . ::. . ::..: : CCDS86 MHRYQKAAKLFQGKILFILVDSGMKENGKVISFFKLKESQLPALAIYQTLDDEWDTL-P- 180 190 200 210 220 230 340 350 360 370 380 390 pF1KB5 SEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFV . :...:.. .:: :: ::. CCDS86 TAEVSVEHVQNFCDGFLSGKLLKENRESEGKTPKVEL 240 250 260 270 >>CCDS35082.1 ERP44 gene_id:23071|Hs108|chr9 (406 aa) initn: 190 init1: 122 opt: 329 Z-score: 356.4 bits: 75.2 E(32554): 1.6e-13 Smith-Waterman score: 340; 23.6% identity (54.9% similar) in 377 aa overlap (26-395:31-392) 10 20 30 40 50 pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGH . : :. : : ::.::: :: CCDS35 MHPAVFLSLPDLRCSLLLLVTWVFTPVTTEITSLDTENIDEILNNADVALVNFYADWCRF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 CKALAPEYAKAAGKLKAE---GSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTAS . : : . .:. .: : ... .:.:: ..::.::.: . :::.:.:::: CCDS35 SQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNG-MMM 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 PKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQF .:: . : . ........ . . : : .: . :. .::.:.. .::. . : CCDS35 KREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL-DRSKRNIIGYFEQKDSDNYRVF 120 130 140 150 160 170 180 190 200 210 220 pF1KB5 LQAAEAI-DDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNN--FEGEVTKENLL-DF ..:. . :: : ... .:: . . . :... .: .. . . : .:. .. .. CCDS35 ERVANILHDDCAF-LSAFGDVSKPERYSGDNII-YKPPGHSAPDMVYLGAMTNFDVTYNW 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILF :. . .::: :.: ... .. . ::. . ... . . .. : :: : : CCDS35 IQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINF 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 IFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLE . : :. . : . .::.. . .... : . .. : .. .: . CCDS35 LHADCDKFRHP--LLHIQKTPADCPVIAIDSFRH-MYVFGDFKDVLIPGKLKQFVFDLHS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 GKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWD ::. : .. :. : : :.. .::: . .. : .. :: CCDS35 GKL--HREFHHGPDPTDTAP-----GEQAQDVASSPPESSFQKL-APSEYRYTLLRDRDE 360 370 380 390 400 410 420 430 440 450 460 pF1KB5 KLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKK CCDS35 L >>CCDS32840.1 TMX3 gene_id:54495|Hs108|chr18 (454 aa) initn: 288 init1: 249 opt: 320 Z-score: 346.1 bits: 73.4 E(32554): 5.9e-13 Smith-Waterman score: 320; 31.3% identity (63.6% similar) in 195 aa overlap (45-229:45-232) 20 30 40 50 60 70 pF1KB5 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG ::.:::::::::: : : . ... ..:. : CCDS32 TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB5 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG : ....:.::: :..:...:::::::::... :: : .: . : :::... .. .: CCDS32 SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLA--YNYRGPRTKDDIIEFAHRVSG 80 90 100 110 120 130 140 150 160 170 180 190 pF1KB5 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV ::. : . . .: :: : :: .....:: . . .... .: CCDS32 ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV 140 150 160 170 180 200 210 220 230 240 pF1KB5 FSKYQLDKD--GVVLFKK-----FDEGRN-NFEGEVTKENLLDFIKHNQLPLVIEFTEQT .: :. .:..:: .:: .. .. . ...: . ... CCDS32 VPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLYELGDTGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 APKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEF CCDS32 LVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVP 250 260 270 280 290 300 508 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:38:24 2016 done: Sat Nov 5 15:38:25 2016 Total Scan time: 3.340 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]