Result of FASTA (omim) for
pF1KB5939
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5939, 508 aa
1>>>pF1KB5939 508 - 508 aa - 508 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7933+/-0.000395; mu= 16.4917+/- 0.025
mean_var=94.9331+/-18.777, 0's: 0 Z-trim(113.7): 39 B-trim: 59 in 1/52
Lambda= 0.131633
statistics sampled from 23092 (23127) to 23092 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.271), width: 16
Scan time: 8.290
The best scores are: opt bits E(85289)
NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508) 3358 648.4 1.4e-185
NP_006840 (OMIM: 608012) protein disulfide-isomera ( 525) 1571 309.1 2.1e-83
NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505) 643 132.8 2.3e-30
NP_689534 (OMIM: 610642) endoplasmic reticulum res ( 273) 426 91.4 3.6e-18
NP_055866 (OMIM: 609170) endoplasmic reticulum res ( 406) 329 73.1 1.7e-12
XP_011524337 (OMIM: 616102) PREDICTED: protein dis ( 229) 318 70.8 4.7e-12
XP_011524336 (OMIM: 616102) PREDICTED: protein dis ( 231) 318 70.8 4.8e-12
NP_061895 (OMIM: 616102) protein disulfide-isomera ( 454) 320 71.4 6.1e-12
NP_001139021 (OMIM: 616412) thioredoxin domain-con ( 324) 279 63.5 1e-09
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432) 279 63.6 1.3e-09
NP_001287713 (OMIM: 610642) endoplasmic reticulum ( 172) 273 62.2 1.4e-09
NP_006801 (OMIM: 616942) protein disulfide-isomera ( 519) 257 59.5 2.7e-08
NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698) 207 50.1 2.5e-05
XP_006724289 (OMIM: 609063,616811) PREDICTED: thio ( 166) 197 47.7 3.1e-05
NP_036605 (OMIM: 609063,616811) thioredoxin, mitoc ( 166) 197 47.7 3.1e-05
XP_005261565 (OMIM: 609063,616811) PREDICTED: thio ( 197) 197 47.8 3.5e-05
XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402) 201 48.8 3.6e-05
NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437) 201 48.8 3.8e-05
NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440) 201 48.8 3.8e-05
NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445) 201 48.8 3.8e-05
NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488) 201 48.9 4.1e-05
NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492) 201 48.9 4.2e-05
NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604) 194 47.6 0.00012
NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747) 194 47.7 0.00014
NP_001222 (OMIM: 114250,616231) calsequestrin-1 pr ( 396) 162 41.4 0.006
>>NP_000909 (OMIM: 112240,176790) protein disulfide-isom (508 aa)
initn: 3358 init1: 3358 opt: 3358 Z-score: 3452.7 bits: 648.4 E(85289): 1.4e-185
Smith-Waterman score: 3358; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508)
10 20 30 40 50 60
pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD
430 440 450 460 470 480
490 500
pF1KB5 DDDLEDLEEAEEPDMEEDDDQKAVKDEL
::::::::::::::::::::::::::::
NP_000 DDDLEDLEEAEEPDMEEDDDQKAVKDEL
490 500
>>NP_006840 (OMIM: 608012) protein disulfide-isomerase A (525 aa)
initn: 1561 init1: 752 opt: 1571 Z-score: 1618.4 bits: 309.1 E(85289): 2.1e-83
Smith-Waterman score: 1571; 50.0% identity (76.5% similar) in 468 aa overlap (18-474:32-495)
10 20 30 40
pF1KB5 MLRRALLCLAVAALVRADAPEEE----DHVLVLRKSNFAEALAAHKY
. :::: : .::: . ... :: :
NP_006 SRQLLPVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIK
:::::::::::::.::::::.:::. : ::. . :::::. . .::...:: :::.:
NP_006 LLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 FFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKD
:::::. . :.:::. :.:. :..::..:.::.: : : :::..:. . ...:::::.:
NP_006 FFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 VESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKE
...... :: :. :. ::.:. .:... : :: ::::::::::: .: : .:
NP_006 LQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLTKDTVVLFKKFDEGRADFP--VDEE
190 200 210 220 230
230 240 250 260 270
pF1KB5 NLLD------FIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKT
:: :. ... :: ::. ::. :::...: .:.:::. .... . :..:
NP_006 LGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 AAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKP-ESEELTA
:: :.:..::. .: .::...:..:::: : :..::..:: :: : .. .::
NP_006 AAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPTLRLVNLETT-KKYAPVDGGPVTA
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 ERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPW
:: ::: :.:..::.:.:::.: :::..:::.:::::::.::::: :::::.:::::
NP_006 ASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPW
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB5 CGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVID
: :::..:: :. :.: :.:::.:.::..:.::::..: ::.:::::.:::. : ::.
NP_006 CTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIE
420 430 440 450 460 470
460 470 480 490 500
pF1KB5 YNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
:.. : :. :.:::..::
NP_006 YKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL
480 490 500 510 520
>>NP_005304 (OMIM: 602046) protein disulfide-isomerase A (505 aa)
initn: 675 init1: 280 opt: 643 Z-score: 666.2 bits: 132.8 E(85289): 2.3e-30
Smith-Waterman score: 853; 34.7% identity (63.5% similar) in 498 aa overlap (2-471:3-481)
10 20 30 40 50
pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA---AHKYLLVEFYAPWCGHC
::: : .:: :. : . :: : .:: .. . .::::.:::::::
NP_005 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 KALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEY
: ::::: :: .::. . ::::: : ... ..::: ::::.:.::.:. :. :
NP_005 KRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AY
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 TAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAA
. : :: ::. :::..:::.. : .... .......::: : :.. ..::.::
NP_005 DGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAA
120 130 140 150 160 170
180 190 200 210 220
pF1KB5 EAI-DDIPFGITSNSDVFSKYQLDKDGVVLFK------KFDEGRNNF-EGEVTKENLLDF
. :. :. :. .. ..:. . .:..::. ::.. . : ..:. .. :
NP_005 SNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYD--GKLSNFKTAAESFKGKI
:..: . . ..::.. : : . ::. .: ::. .: ::. .....
NP_005 IQENIFGICPHMTEDNKDLIQGKD-----LLIAYYDV-DYEKNAKGSNY------WRNRV
240 250 260 270 280
290 300 310 320 330
pF1KB5 LFI---FIDSDHTDNQRI---------LEFFGLKKE--ECPAVRLITLEEEMTKYKPESE
... :.:. : : . : :::.. : :.: . : . : .. :
NP_005 MMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFS
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB5 ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF
. .. . .: . ...:..: .: :. .::. : ::::.:..::.... .:.:.:..::
NP_005 R-DGKALERFLQDYFDGNLKRYLKSEPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEF
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB5 YAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASAD
:::::::::.: : . .::: . ::::::::.:::.: . .:..:::. : ::.
NP_005 YAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKK
410 420 430 440 450 460
460 470 480 490 500
pF1KB5 RTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
. :.: : :. : ..:.
NP_005 LNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL
470 480 490 500
>>NP_689534 (OMIM: 610642) endoplasmic reticulum residen (273 aa)
initn: 318 init1: 156 opt: 426 Z-score: 447.1 bits: 91.4 E(85289): 3.6e-18
Smith-Waterman score: 426; 32.5% identity (65.4% similar) in 231 aa overlap (130-351:29-257)
100 110 120 130 140 150
pF1KB5 PTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLP----DGAAAESLVESSEV
:. ::.:. : : :: .. ..::
NP_689 MEAAPSRFMFLLFLLTCELAAEVAAEVEKSSDGPGAAQEPTWLTDVPAAMEFIAATEV
10 20 30 40 50
160 170 180 190 200 210
pF1KB5 AVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNN
::::::.:.: .. . . .. . . :::...:.:...:.. . . ::. :. . :
NP_689 AVIGFFQDLEIPAVPILHSMVQKFPGVSFGISTDSEVLTHYNITGNTICLFRLVDNEQLN
60 70 80 90 100 110
220 230 240 250 260 270
pF1KB5 FEGE----VTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGK
.: : . .: ::. :.: .: :.. :. .:.. :. :.::.. :. .:. .
NP_689 LEDEDIESIDATKLSRFIEINSLHMVTEYNPVTVIGLFNSVIQIHLLLIMNKASPEYEEN
120 130 140 150 160 170
280 290 300 310 320 330
pF1KB5 LSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLI-TLEEEMTKYKPE
. .. ::. :.::::::..:: .: ... :: ::. . ::. . ::..: :
NP_689 MHRYQKAAKLFQGKILFILVDSGMKENGKVISFFKLKESQLPALAIYQTLDDEWDTL-P-
180 190 200 210 220 230
340 350 360 370 380 390
pF1KB5 SEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFV
. :...:.. .:: :: ::.
NP_689 TAEVSVEHVQNFCDGFLSGKLLKENRESEGKTPKVEL
240 250 260 270
>>NP_055866 (OMIM: 609170) endoplasmic reticulum residen (406 aa)
initn: 190 init1: 122 opt: 329 Z-score: 345.2 bits: 73.1 E(85289): 1.7e-12
Smith-Waterman score: 340; 23.6% identity (54.9% similar) in 377 aa overlap (26-395:31-392)
10 20 30 40 50
pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGH
. : :. : : ::.::: ::
NP_055 MHPAVFLSLPDLRCSLLLLVTWVFTPVTTEITSLDTENIDEILNNADVALVNFYADWCRF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 CKALAPEYAKAAGKLKAE---GSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTAS
. : : . .:. .: : ... .:.:: ..::.::.: . :::.:.::::
NP_055 SQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNG-MMM
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQF
.:: . : . ........ . . : : .: . :. .::.:.. .::. . :
NP_055 KREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL-DRSKRNIIGYFEQKDSDNYRVF
120 130 140 150 160 170
180 190 200 210 220
pF1KB5 LQAAEAI-DDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNN--FEGEVTKENLL-DF
..:. . :: : ... .:: . . . :... .: .. . . : .:. .. ..
NP_055 ERVANILHDDCAF-LSAFGDVSKPERYSGDNII-YKPPGHSAPDMVYLGAMTNFDVTYNW
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILF
:. . .::: :.: ... .. . ::. . ... . . .. : :: : :
NP_055 IQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 IFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLE
. : :. . : . .::.. . .... : . .. : .. .: .
NP_055 LHADCDKFRHP--LLHIQKTPADCPVIAIDSFRH-MYVFGDFKDVLIPGKLKQFVFDLHS
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 GKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWD
::. : .. :. : : :.. .::: . .. : .. ::
NP_055 GKL--HREFHHGPDPTDTAP-----GEQAQDVASSPPESSFQKL-APSEYRYTLLRDRDE
360 370 380 390 400
410 420 430 440 450 460
pF1KB5 KLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKK
NP_055 L
>>XP_011524337 (OMIM: 616102) PREDICTED: protein disulfi (229 aa)
initn: 288 init1: 249 opt: 318 Z-score: 337.3 bits: 70.8 E(85289): 4.7e-12
Smith-Waterman score: 318; 34.7% identity (64.7% similar) in 167 aa overlap (45-207:45-204)
20 30 40 50 60 70
pF1KB5 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG
::.:::::::::: : : . ... ..:. :
XP_011 TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB5 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG
: ....:.::: :..:...:::::::::... :: : .: . : :::... .. .:
XP_011 SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAY--NYRGPRTKDDIIEFAHRVSG
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB5 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV
::. : . . .: :: : :: .....:: . . .... .:
XP_011 ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV
140 150 160 170 180
200 210 220 230 240 250
pF1KB5 FSKYQLDKD--GVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFG
.: :. .:..::
XP_011 VPEYVTLKEMPAVLVFKDETYFVYDDNNYTLMLSYKRYYLHT
190 200 210 220
>>XP_011524336 (OMIM: 616102) PREDICTED: protein disulfi (231 aa)
initn: 288 init1: 249 opt: 318 Z-score: 337.3 bits: 70.8 E(85289): 4.8e-12
Smith-Waterman score: 318; 34.7% identity (64.7% similar) in 167 aa overlap (45-207:45-204)
20 30 40 50 60 70
pF1KB5 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG
::.:::::::::: : : . ... ..:. :
XP_011 TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB5 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG
: ....:.::: :..:...:::::::::... :: : .: . : :::... .. .:
XP_011 SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAY--NYRGPRTKDDIIEFAHRVSG
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB5 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV
::. : . . .: :: : :: .....:: . . .... .:
XP_011 ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV
140 150 160 170 180
200 210 220 230 240 250
pF1KB5 FSKYQLDKD--GVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFG
.: :. .:..::
XP_011 VPEYVTLKEMPAVLVFKDETYFVYDAFILDSESTCAGLLHGCIG
190 200 210 220 230
>>NP_061895 (OMIM: 616102) protein disulfide-isomerase T (454 aa)
initn: 288 init1: 249 opt: 320 Z-score: 335.3 bits: 71.4 E(85289): 6.1e-12
Smith-Waterman score: 320; 31.3% identity (63.6% similar) in 195 aa overlap (45-229:45-232)
20 30 40 50 60 70
pF1KB5 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG
::.:::::::::: : : . ... ..:. :
NP_061 TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB5 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG
: ....:.::: :..:...:::::::::... :: : .: . : :::... .. .:
NP_061 SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLA--YNYRGPRTKDDIIEFAHRVSG
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB5 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV
::. : . . .: :: : :: .....:: . . .... .:
NP_061 ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV
140 150 160 170 180
200 210 220 230 240
pF1KB5 FSKYQLDKD--GVVLFKK-----FDEGRN-NFEGEVTKENLLDFIKHNQLPLVIEFTEQT
.: :. .:..:: .:: .. .. . ...: . ...
NP_061 VPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLYELGDTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 APKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEF
NP_061 LVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVP
250 260 270 280 290 300
>>NP_001139021 (OMIM: 616412) thioredoxin domain-contain (324 aa)
initn: 426 init1: 235 opt: 279 Z-score: 295.2 bits: 63.5 E(85289): 1e-09
Smith-Waterman score: 279; 39.5% identity (71.1% similar) in 114 aa overlap (13-125:202-312)
10 20 30 40
pF1KB5 MLRRALLCLAVAALVRADAPE-EEDHVLVLRKSNFAEALAAH
: : : :: .. ::.: ..:: ...: .
NP_001 KRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIA-E
180 190 200 210 220 230
50 60 70 80 90 100
pF1KB5 KYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPT
...::::::::::.::: . . . : . ...:.:: : : .. ..:.::::::
NP_001 GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPT
240 250 260 270 280 290
110 120 130 140 150 160
pF1KB5 IKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFF
. .::.: .: :...::. :..
NP_001 LLLFRGGKKVS--EHSGGRDLDSLHRFVLSQAKDEL
300 310 320
>--
initn: 331 init1: 187 opt: 243 Z-score: 258.3 bits: 56.7 E(85289): 1.2e-07
Smith-Waterman score: 251; 36.4% identity (65.9% similar) in 129 aa overlap (19-141:76-199)
10 20 30 40
pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEF
::: .. . : ::: : .:. ...:
NP_001 PRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNF-ELHVAQGDHFIKF
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB5 YAPWCGHCKALAPEYAKAAGKLKAEGSE-IRLAKVDATEESDLAQQYGVRGYPTIKFFRN
.:::::::::::: . . : : : :: ....::: :.. .: . ::::::. .::.
NP_001 FAPWCGHCKALAPTWEQLA--LGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRD
110 120 130 140 150 160
110 120 130 140 150 160
pF1KB5 GDTASPKEYTAGREADDIVNWLKKR-----TGPAATTLPDGAAAESLVESSEVAVIGFFK
: .. .: . :. ... ...... :: . :. :
NP_001 GKKVD--QYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALT
170 180 190 200 210 220
170 180 190 200 210 220
pF1KB5 DVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTK
NP_001 ENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNIC
230 240 250 260 270 280
>>NP_110437 (OMIM: 616412) thioredoxin domain-containing (432 aa)
initn: 492 init1: 235 opt: 279 Z-score: 293.5 bits: 63.6 E(85289): 1.3e-09
Smith-Waterman score: 279; 39.5% identity (71.1% similar) in 114 aa overlap (13-125:310-420)
10 20 30 40
pF1KB5 MLRRALLCLAVAALVRADAPE-EEDHVLVLRKSNFAEALAAH
: : : :: .. ::.: ..:: ...: .
NP_110 KRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIA-E
280 290 300 310 320 330
50 60 70 80 90 100
pF1KB5 KYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPT
...::::::::::.::: . . . : . ...:.:: : : .. ..:.::::::
NP_110 GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPT
340 350 360 370 380 390
110 120 130 140 150 160
pF1KB5 IKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFF
. .::.: .: :...::. :..
NP_110 LLLFRGGKKVS--EHSGGRDLDSLHRFVLSQAKDEL
400 410 420 430
>--
initn: 406 init1: 187 opt: 243 Z-score: 256.6 bits: 56.8 E(85289): 1.5e-07
Smith-Waterman score: 251; 36.4% identity (65.9% similar) in 129 aa overlap (19-141:184-307)
10 20 30 40
pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEF
::: .. . : ::: : .:. ...:
NP_110 PRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNF-ELHVAQGDHFIKF
160 170 180 190 200 210
50 60 70 80 90 100
pF1KB5 YAPWCGHCKALAPEYAKAAGKLKAEGSE-IRLAKVDATEESDLAQQYGVRGYPTIKFFRN
.:::::::::::: . . : : : :: ....::: :.. .: . ::::::. .::.
NP_110 FAPWCGHCKALAPTWEQLA--LGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRD
220 230 240 250 260 270
110 120 130 140 150 160
pF1KB5 GDTASPKEYTAGREADDIVNWLKKR-----TGPAATTLPDGAAAESLVESSEVAVIGFFK
: .. .: . :. ... ...... :: . :. :
NP_110 GKKVD--QYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALT
280 290 300 310 320
170 180 190 200 210 220
pF1KB5 DVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTK
NP_110 ENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNIC
330 340 350 360 370 380
>--
initn: 271 init1: 158 opt: 222 Z-score: 235.0 bits: 52.8 E(85289): 2.4e-06
Smith-Waterman score: 248; 36.4% identity (61.2% similar) in 129 aa overlap (12-129:41-164)
10 20 30
pF1KB5 MLRRALLCLAVAALVRADAPEEED-------HVLVLRKSN-
:: . ::.: : : : ..
NP_110 LLARPAALTALLLLLLGHGGGGRWGARAQEAAAAAADGPPAADGEDGQDPHSKHLYTADM
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB5 FAEAL--AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKA-EGSEIRLAKVDATEESDL
:.... ::: .: :.:::::::. : : . . : .. : ... .:::: : .::.
NP_110 FTHGIQSAAH---FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDV
80 90 100 110 120
100 110 120 130 140 150
pF1KB5 AQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLV
. :::::::.:.:. :. : .: . :. . . ::.
NP_110 CSAQGVRGYPTLKLFKPGQEAV--KYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 ESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFD
NP_110 ELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKV
190 200 210 220 230 240
508 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:38:25 2016 done: Sat Nov 5 15:38:27 2016
Total Scan time: 8.290 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]