FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5946, 495 aa 1>>>pF1KB5946 495 - 495 aa - 495 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5343+/-0.00105; mu= 13.1422+/- 0.063 mean_var=109.0693+/-22.257, 0's: 0 Z-trim(106.9): 130 B-trim: 222 in 1/50 Lambda= 0.122807 statistics sampled from 9259 (9391) to 9259 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.281), width: 16 Scan time: 1.490 The best scores are: opt bits E(33420) CCDS1400.1 NR5A2 gene_id:2494|Hs109|chr1 ( 495) 3315 598.4 6e-171 CCDS1401.1 NR5A2 gene_id:2494|Hs109|chr1 ( 541) 3187 575.7 4.4e-164 CCDS60383.1 NR5A2 gene_id:2494|Hs109|chr1 ( 469) 3149 569.0 4.1e-162 CCDS6856.1 NR5A1 gene_id:2516|Hs109|chr9 ( 461) 1900 347.7 1.7e-95 CCDS6744.1 NR4A3 gene_id:8013|Hs109|chr9 ( 443) 416 84.7 2.3e-16 CCDS6646.1 RORB gene_id:6096|Hs109|chr9 ( 459) 415 84.6 2.7e-16 CCDS6743.1 NR4A3 gene_id:8013|Hs109|chr9 ( 626) 413 84.3 4.4e-16 CCDS6742.1 NR4A3 gene_id:8013|Hs109|chr9 ( 637) 413 84.3 4.4e-16 CCDS86887.1 NR4A2 gene_id:4929|Hs109|chr2 ( 535) 404 82.7 1.2e-15 CCDS45359.1 NR2F2 gene_id:7026|Hs109|chr15 ( 261) 399 81.6 1.2e-15 CCDS2201.1 NR4A2 gene_id:4929|Hs109|chr2 ( 598) 404 82.7 1.3e-15 CCDS45358.1 NR2F2 gene_id:7026|Hs109|chr15 ( 281) 399 81.6 1.3e-15 CCDS55340.1 NR6A1 gene_id:2649|Hs109|chr9 ( 475) 401 82.1 1.5e-15 CCDS35137.1 NR6A1 gene_id:2649|Hs109|chr9 ( 480) 400 81.9 1.7e-15 CCDS35172.1 RXRA gene_id:6256|Hs109|chr9 ( 462) 397 81.4 2.4e-15 CCDS1517.1 ESRRG gene_id:2104|Hs109|chr1 ( 435) 396 81.2 2.6e-15 CCDS41468.1 ESRRG gene_id:2104|Hs109|chr1 ( 458) 396 81.2 2.7e-15 CCDS8818.1 NR4A1 gene_id:3164|Hs109|chr12 ( 598) 396 81.3 3.4e-15 CCDS55828.1 NR4A1 gene_id:3164|Hs109|chr12 ( 611) 396 81.3 3.5e-15 CCDS65127.1 NR6A1 gene_id:2649|Hs109|chr9 ( 476) 394 80.9 3.6e-15 CCDS73471.1 NR4A1 gene_id:3164|Hs109|chr12 ( 652) 396 81.3 3.6e-15 CCDS4768.1 RXRB gene_id:6257|Hs109|chr6 ( 533) 392 80.5 5.1e-15 CCDS59007.1 RXRB gene_id:6257|Hs109|chr6 ( 537) 392 80.5 5.1e-15 CCDS58061.1 ESRRG gene_id:2104|Hs109|chr1 ( 470) 390 80.1 5.8e-15 CCDS9850.2 ESRRB gene_id:2103|Hs109|chr14 ( 508) 388 79.8 8e-15 CCDS1248.1 RXRG gene_id:6258|Hs109|chr1 ( 463) 384 79.1 1.2e-14 CCDS72970.1 RXRG gene_id:6258|Hs109|chr1 ( 340) 381 78.5 1.4e-14 CCDS45271.1 RORA gene_id:6095|Hs109|chr15 ( 468) 380 78.4 2e-14 CCDS10177.1 RORA gene_id:6095|Hs109|chr15 ( 523) 380 78.4 2.2e-14 CCDS10178.1 RORA gene_id:6095|Hs109|chr15 ( 548) 380 78.4 2.3e-14 CCDS10179.1 RORA gene_id:6095|Hs109|chr15 ( 556) 380 78.4 2.3e-14 CCDS60830.1 ESRRA gene_id:2101|Hs109|chr11 ( 422) 378 78.0 2.3e-14 CCDS41667.1 ESRRA gene_id:2101|Hs109|chr11 ( 423) 378 78.0 2.3e-14 CCDS11361.1 NR1D1 gene_id:9572|Hs109|chr17 ( 614) 373 77.2 5.8e-14 CCDS30856.1 RORC gene_id:6097|Hs109|chr1 ( 497) 368 76.3 9.1e-14 CCDS1004.1 RORC gene_id:6097|Hs109|chr1 ( 518) 368 76.3 9.4e-14 CCDS58236.1 RARG gene_id:5916|Hs109|chr12 ( 382) 364 75.5 1.2e-13 CCDS41790.1 RARG gene_id:5916|Hs109|chr12 ( 443) 364 75.5 1.4e-13 CCDS8850.1 RARG gene_id:5916|Hs109|chr12 ( 454) 364 75.5 1.4e-13 CCDS58060.1 ESRRG gene_id:2104|Hs109|chr1 ( 396) 363 75.3 1.4e-13 CCDS42317.1 RARA gene_id:5914|Hs109|chr17 ( 457) 359 74.6 2.6e-13 CCDS11366.1 RARA gene_id:5914|Hs109|chr17 ( 462) 359 74.6 2.6e-13 CCDS74905.1 NR2C2 gene_id:7182|Hs109|chr3 ( 596) 360 74.9 2.8e-13 CCDS2621.1 NR2C2 gene_id:7182|Hs109|chr3 ( 615) 360 74.9 2.9e-13 CCDS2641.1 THRB gene_id:7068|Hs109|chr3 ( 461) 357 74.3 3.3e-13 CCDS42316.1 THRA gene_id:7067|Hs109|chr17 ( 410) 356 74.1 3.4e-13 CCDS58546.1 THRA gene_id:7067|Hs109|chr17 ( 451) 356 74.1 3.7e-13 CCDS11360.1 THRA gene_id:7067|Hs109|chr17 ( 490) 356 74.1 3.9e-13 CCDS2642.1 RARB gene_id:5915|Hs109|chr3 ( 448) 355 73.9 4.1e-13 CCDS10375.1 NR2F2 gene_id:7026|Hs109|chr15 ( 414) 351 73.2 6.3e-13 >>CCDS1400.1 NR5A2 gene_id:2494|Hs109|chr1 (495 aa) initn: 3315 init1: 3315 opt: 3315 Z-score: 3182.7 bits: 598.4 E(33420): 6e-171 Smith-Waterman score: 3315; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:1-495) 10 20 30 40 50 60 pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV 430 440 450 460 470 480 490 pF1KB5 PYNNLLIEMLHAKRA ::::::::::::::: CCDS14 PYNNLLIEMLHAKRA 490 >>CCDS1401.1 NR5A2 gene_id:2494|Hs109|chr1 (541 aa) initn: 3301 init1: 3180 opt: 3187 Z-score: 3059.6 bits: 575.7 E(33420): 4.4e-164 Smith-Waterman score: 3187; 96.8% identity (98.4% similar) in 493 aa overlap (3-495:55-541) 10 20 30 pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSY :... :.. :... ::::::::::: CCDS14 LPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQ------VSQFKMVNYSY 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 DEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRC 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 PYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQ 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 VIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGY 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB5 QTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQV 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB5 QAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLL 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB5 QNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB5 RSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQ 440 450 460 470 480 490 460 470 480 490 pF1KB5 LLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA ::::::::::::::::::::::::::::::::::::::::::: CCDS14 LLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA 500 510 520 530 540 >>CCDS60383.1 NR5A2 gene_id:2494|Hs109|chr1 (469 aa) initn: 3149 init1: 3149 opt: 3149 Z-score: 3024.1 bits: 569.0 E(33420): 4.1e-162 Smith-Waterman score: 3149; 100.0% identity (100.0% similar) in 469 aa overlap (27-495:1-469) 10 20 30 40 50 60 pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC :::::::::::::::::::::::::::::::::: CCDS60 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC 10 20 30 70 80 90 100 110 120 pF1KB5 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV 400 410 420 430 440 450 490 pF1KB5 PYNNLLIEMLHAKRA ::::::::::::::: CCDS60 PYNNLLIEMLHAKRA 460 >>CCDS6856.1 NR5A1 gene_id:2516|Hs109|chr9 (461 aa) initn: 1857 init1: 879 opt: 1900 Z-score: 1828.2 bits: 347.7 E(33420): 1.7e-95 Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (28-494:1-460) 10 20 30 40 50 60 pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC ..:::::::.::::::::::::::::::::::: CCDS68 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESC 10 20 30 70 80 90 100 110 120 pF1KB5 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN ::::::::::::.::: :.:.:.::::::::::.:::::::.:::.:::::::::::::: CCDS68 KGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRN 40 50 60 70 80 90 130 140 150 160 170 pF1KB5 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQV-IQAMPSDLTISSAIQNIHSAS-KGLP :::::::::::::::::: :::::.:::. . . : ..:. ::: CCDS68 KFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGL- 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB5 LNHAALPPTDYDRSPFVTSPISMTMP-PHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPES :: ::. . : . . :..: :: : :: : ::.::::::::.::.: :. CCDS68 ---AAGPPAG-PLGDFGAPALPMAVPGAHGPLAGY-LYPAFPGRAIKSEYPEPYASPPQP 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 IMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFG . :.: . . ...: ..:.:::.::. :::: ::.:.:.. ::. ..:. .. ..:: CCDS68 GLPYGYPEPF-SGGP-NVPELILQLLQLEPDEDQVRARILGCLQEP--TKSRPDQPAAFG 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 LMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSI :.:.:::::..:::.::: . :.::.: ::: ::::::::::..::::::: ::::::: CCDS68 LLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSI 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB5 FLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN .:::::.:. . .:.:::. :..:. .::::: .: .::.:..:::::::..:::::.: CCDS68 LLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKF 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB5 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN :.: ::. .::..::::::::.:.::. .:: :::: : :.::.::::.::::.:::. CCDS68 LNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLG 390 400 410 420 430 440 480 490 pF1KB5 GDVPYNNLLIEMLHAKRA ...: ::::::::.::. CCDS68 NEMPRNNLLIEMLQAKQT 450 460 >>CCDS6744.1 NR4A3 gene_id:8013|Hs109|chr9 (443 aa) initn: 388 init1: 388 opt: 416 Z-score: 407.5 bits: 84.7 E(33420): 2.3e-16 Smith-Waterman score: 416; 42.7% identity (67.3% similar) in 150 aa overlap (37-179:289-435) 10 20 30 40 50 60 pF1KB5 TGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKR : : ::::... :::. :::.::::::: CCDS67 LGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKR 260 270 280 290 300 310 70 80 90 100 110 120 pF1KB5 TVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMY :::.: .:.:. :.:: .:: .:.:: :::::::::::: :.::.: ..: : : . CCDS67 TVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRR---GRLP 320 330 340 350 360 370 130 140 150 160 170 pF1KB5 KRDRALKQQKKALIRANGLKLEAMSQVIQAM----PSDLT---ISSAIQNIHSASKGLPL .. .. ::. . . . :. ...:. : :: .: :. .. ..:: : CCDS67 SKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRVSFMISCFQMNDQGLYL 380 390 400 410 420 430 180 190 200 210 220 230 pF1KB5 NHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIM CCDS67 WLLVIRVD 440 >>CCDS6646.1 RORB gene_id:6096|Hs109|chr9 (459 aa) initn: 457 init1: 364 opt: 415 Z-score: 406.3 bits: 84.6 E(33420): 2.7e-16 Smith-Waterman score: 493; 27.1% identity (59.7% similar) in 457 aa overlap (40-480:10-437) 10 20 30 40 50 60 pF1KB5 LQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQ : .:::: :: :::..:::.:::::.:. : CCDS66 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ 10 20 30 70 80 90 100 110 120 pF1KB5 NNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRM-RGGRNK-FGPMYK :: :.: ...:: ::.:.:.:: .::.::::..::. .::. :: . :.. .. . : CCDS66 NNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQK 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 RDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPT ... :..:.. . .: . ::...: .. .::....:... ..: : .. CCDS66 HQQRLQEQRQ---QQSG-EAEALARVYSS-----SISNGLSNLNNETSGTYANGHVI--- 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 DYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSY : .: . : : : : . : . ::.: :: : ... :: ... CCDS66 DLPKSEGYYNVDSGQPSPDQS--GLDMTG---IKQIKQEPIYDLTSVP-NLFTYSSFNNG 150 160 170 180 190 200 250 260 270 280 290 pF1KB5 QTSSPAS---IPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTF------GL : . . : .. ...: . . : : :.: . .:..... .: CCDS66 QLAPGITMTEIDRIAQNIIKSHLETCQY---TMEELHQLAWQTHTYEEIKAYQSKSREAL 210 220 230 240 250 300 310 320 330 340 350 pF1KB5 MCKMADQTLFSI---VEWARSSIFFRELKVDDQMKLLQN-CWSELLILDHIYRQVVHGKE . : : .: ::.:. : :: .::. ::.. : .:. .. : . . CCDS66 WQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLV--RMCR--AFNPL 260 270 280 290 300 310 360 370 380 390 400 410 pF1KB5 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLD .. : :. .... . .. ..:...: ... .: :::. ..:.. .. ::.: : CCDS66 NNTVLFEGKYGGMQMFKALGS---DDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPD 320 330 340 350 360 370 420 430 440 450 460 470 pF1KB5 VKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAI-SMQAEEYLYY : . . :. .::.. :: . :. . : ...:. ..: : :. ....:. . CCDS66 RAWLIEPRKVQKLQEKIYFALQHVIQKNH-LDDETLAKLIAKIPTITAVCNLHGEKLQVF 380 390 400 410 420 430 480 490 pF1KB5 KHLNGDVPYNNLLIEMLHAKRA :. . .. CCDS66 KQSHPEIVNTLFPPLYKELFNPDCATGCK 440 450 >>CCDS6743.1 NR4A3 gene_id:8013|Hs109|chr9 (626 aa) initn: 435 init1: 388 opt: 413 Z-score: 402.5 bits: 84.3 E(33420): 4.4e-16 Smith-Waterman score: 413; 45.5% identity (68.9% similar) in 132 aa overlap (37-164:289-417) 10 20 30 40 50 60 pF1KB5 TGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKR : : ::::... :::. :::.::::::: CCDS67 LGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKR 260 270 280 290 300 310 70 80 90 100 110 120 pF1KB5 TVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMY :::.: .:.:. :.:: .:: .:.:: :::::::::::: :.::.: ..: : : . CCDS67 TVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRR---GRLP 320 330 340 350 360 370 130 140 150 160 170 180 pF1KB5 KRDRALKQQKKALIRANGLKLEAMSQVIQAM----PSDLTISSAIQNIHSASKGLPLNHA .. .. ::. . . . :. ...:. : :: : CCDS67 SKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQ 380 390 400 410 420 430 190 200 210 220 230 240 pF1KB5 ALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYS CCDS67 QFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVF 440 450 460 470 480 490 >>CCDS6742.1 NR4A3 gene_id:8013|Hs109|chr9 (637 aa) initn: 435 init1: 388 opt: 413 Z-score: 402.4 bits: 84.3 E(33420): 4.4e-16 Smith-Waterman score: 413; 45.5% identity (68.9% similar) in 132 aa overlap (37-164:300-428) 10 20 30 40 50 60 pF1KB5 TGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKR : : ::::... :::. :::.::::::: CCDS67 LGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKR 270 280 290 300 310 320 70 80 90 100 110 120 pF1KB5 TVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMY :::.: .:.:. :.:: .:: .:.:: :::::::::::: :.::.: ..: : : . CCDS67 TVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRR---GRLP 330 340 350 360 370 380 130 140 150 160 170 180 pF1KB5 KRDRALKQQKKALIRANGLKLEAMSQVIQAM----PSDLTISSAIQNIHSASKGLPLNHA .. .. ::. . . . :. ...:. : :: : CCDS67 SKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQ 390 400 410 420 430 440 190 200 210 220 230 240 pF1KB5 ALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYS CCDS67 QFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVF 450 460 470 480 490 500 >>CCDS86887.1 NR4A2 gene_id:4929|Hs109|chr2 (535 aa) initn: 510 init1: 404 opt: 404 Z-score: 394.8 bits: 82.7 E(33420): 1.2e-15 Smith-Waterman score: 405; 43.4% identity (69.0% similar) in 145 aa overlap (37-171:197-341) 10 20 30 40 50 60 pF1KB5 TGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKR : :: ::::... :::. :::.::::::: CCDS86 MGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKR 170 180 190 200 210 220 70 80 90 100 110 120 pF1KB5 TVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMY :::.: .:.:. :.:: .:: .:.:: ::::::::.::: :.::.: ..: :... CCDS86 TVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKP 230 240 250 260 270 280 130 140 150 160 170 pF1KB5 KRDRALKQQK------KALIRANGLKLEAMSQV----IQAMPSDLTISSAIQNIHSASKG : . . . .::.::. . ::... .:: :. .. :.:. CCDS86 KSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDL 290 300 310 320 330 340 180 190 200 210 220 230 pF1KB5 LPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPE CCDS86 LTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVV 350 360 370 380 390 400 >>CCDS45359.1 NR2F2 gene_id:7026|Hs109|chr15 (261 aa) initn: 400 init1: 275 opt: 399 Z-score: 394.5 bits: 81.6 E(33420): 1.2e-15 Smith-Waterman score: 399; 36.3% identity (69.9% similar) in 193 aa overlap (299-490:59-247) 270 280 290 300 310 320 pF1KB5 EPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQ .:..: . ::: :::::. :: .:.. :: CCDS45 ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 30 40 50 60 70 80 330 340 350 360 370 380 pF1KB5 MKLLQNCWSELLILDHIYRQV-VHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQE . ::. ::::..:. .. .: . .. ..: ... . :... : .... :: CCDS45 VALLRLTWSELFVLNAAQCSMPLH--VAPLLAAAGLHAS-PMSADRVVAFMDHIRIF-QE 90 100 110 120 130 140 390 400 410 420 430 440 pF1KB5 LVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQT : ::..:. :. :. ::: .:::. :. .: . ::..::. . :: .:. .::.: CCDS45 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQP 150 160 170 180 190 200 450 460 470 480 490 pF1KB5 EKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA .::.:::::: .:..: .. : :.. .: : .: ..:. .:: CCDS45 TRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ 210 220 230 240 250 260 495 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Jul 16 15:50:04 2019 done: Tue Jul 16 15:50:05 2019 Total Scan time: 1.490 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]