FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5952, 547 aa
1>>>pF1KB5952 547 - 547 aa - 547 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5233+/-0.000934; mu= 18.2511+/- 0.056
mean_var=88.4393+/-17.785, 0's: 0 Z-trim(107.8): 60 B-trim: 278 in 2/50
Lambda= 0.136380
statistics sampled from 9716 (9775) to 9716 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.3), width: 16
Scan time: 3.070
The best scores are: opt bits E(32554)
CCDS12235.1 ICAM3 gene_id:3385|Hs108|chr19 ( 547) 3657 729.9 1.9e-210
CCDS82290.1 ICAM3 gene_id:3385|Hs108|chr19 ( 470) 3133 626.7 1.9e-179
CCDS12233.1 ICAM5 gene_id:7087|Hs108|chr19 ( 924) 1586 322.6 1.3e-87
CCDS12231.1 ICAM1 gene_id:3383|Hs108|chr19 ( 532) 1577 320.6 2.9e-87
CCDS11657.1 ICAM2 gene_id:3384|Hs108|chr17 ( 275) 419 92.5 6.9e-19
>>CCDS12235.1 ICAM3 gene_id:3385|Hs108|chr19 (547 aa)
initn: 3657 init1: 3657 opt: 3657 Z-score: 3891.6 bits: 729.9 E(32554): 1.9e-210
Smith-Waterman score: 3657; 100.0% identity (100.0% similar) in 547 aa overlap (1-547:1-547)
10 20 30 40 50 60
pF1KB5 MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 EKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 CTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 ERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 QLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 QLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 LQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 AGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTSMQPTEAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTSMQPTEAMG
490 500 510 520 530 540
pF1KB5 EEPSRAE
:::::::
CCDS12 EEPSRAE
>>CCDS82290.1 ICAM3 gene_id:3385|Hs108|chr19 (470 aa)
initn: 3133 init1: 3133 opt: 3133 Z-score: 3335.3 bits: 626.7 E(32554): 1.9e-179
Smith-Waterman score: 3133; 100.0% identity (100.0% similar) in 470 aa overlap (78-547:1-470)
50 60 70 80 90 100
pF1KB5 SLFVNCSTDCPSSEKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITG
::::::::::::::::::::::::::::::
CCDS82 MGWAAFNLSNVTGNSRILCSVYCNGSQITG
10 20 30
110 120 130 140 150 160
pF1KB5 SSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 EEPAEVTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EEPAEVTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 PRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 GAREIVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GAREIVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLD
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 GVPAAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GVPAAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATC
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB5 PQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSS
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB5 RGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 RGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTY
400 410 420 430 440 450
530 540
pF1KB5 LPLTSMQPTEAMGEEPSRAE
::::::::::::::::::::
CCDS82 LPLTSMQPTEAMGEEPSRAE
460 470
>>CCDS12233.1 ICAM5 gene_id:7087|Hs108|chr19 (924 aa)
initn: 1537 init1: 1206 opt: 1586 Z-score: 1686.3 bits: 322.6 E(32554): 1.3e-87
Smith-Waterman score: 1586; 51.6% identity (76.5% similar) in 473 aa overlap (15-480:16-488)
10 20 30 40 50
pF1KB5 MATMVPSVLWPRACWTLLVCCLLTPGVQGQE-FLLRVEPQNPVLSAGGSLFVNCSTDCP
:. : :. .. .:: : ..:. . ::::..::::.::
CCDS12 MPGPSPGLRRALLGLWAALGLGLFGLSAVSQEPFWADLQPRVAFVERGGSLWLNCSTNCP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 SSEKIALETSLSKELVASGMGWAAFNLSNVT-GNSRILCSVYCNGSQITGSSNITVYRLP
:. .::::: .. . :. : : .: .. ... .: : . . . : ... :
CCDS12 RPERGGLETSLRRNGTQRGLRWLARQLVDIREPETQPVCFFRCARRTLQARGLIRTFQRP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 ERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEP-----AE
.:::: :::::::::.:::: :.: ..::.:::..::: .:: :. . :: :
CCDS12 DRVELMPLPPWQPVGENFTLSCRVPGAGPRASLTLTLLRGAQELIRRSFAGEPPRARGAV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 VTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLE
.:::::: :.:::: ::::.:::..:.::::: :.::::.:::: : :::.:::.::
CCDS12 LTATVLARREDHGANFSCRAELDLRPHGLGLFENSSAPRELRTFSLSPDAPRLAAPRLLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 VETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREI
: . ::.::::::::::::.:::::::: :. : .::...::::::: :.:::::..
CCDS12 VGSERPVSCTLDGLFPASEARVYLALGDQNLSPDVTLEGDAFVATATATASAEQEGARQL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 VCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAA
::::::::: ::.:::.:..:: .:...::::.. ::. :::.: :::.. :::.:::::
CCDS12 VCNVTLGGENRETRENVTIYSFPAPLLTLSEPSVSEGQMVTVTCAAGAQALVTLEGVPAA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 APGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLK
.:::::::::::::.:: :::::.:::.:::: : .: :..:::::.:..: . ::.
CCDS12 VPGQPAQLQLNATENDDRRSFFCDATLDVDGETLIKNRSAELRVLYAPRLDDSDCPRSWT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 WKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYT
: . ...:.:.::::: : ..: . .. . .:. :. . .:::.:.:....:. .
CCDS12 WPEGPEQTLRCEARGNPEPSVHCARSDGGAVLALGLLGPVTRALSGTYRCKAANDQGEAV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 LVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTS
:.. .:
CCDS12 KDVTLTVEYAPALDSVGCPERITWLEGTEASLSCVAHGVPPPDVICVRSGELGAVIEGLL
490 500 510 520 530 540
>>CCDS12231.1 ICAM1 gene_id:3383|Hs108|chr19 (532 aa)
initn: 1491 init1: 1403 opt: 1577 Z-score: 1680.0 bits: 320.6 E(32554): 2.9e-87
Smith-Waterman score: 1577; 46.8% identity (74.1% similar) in 532 aa overlap (4-530:1-523)
10 20 30 40 50 60
pF1KB5 MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSS
:.:: : :.. : :: . . : :.. .: :::..:.:::.: .
CCDS12 MAPSSPRPALPALLVLLGALFPGPGNAQ--TSVSPSKVILPRGGSVLVTCSTSCDQP
10 20 30 40 50
70 80 90 100 110
pF1KB5 EKIALETSL-SKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPER
. ...:: : .:::. : . ...:::: .:. .: : .: :... .::: :::
CCDS12 KLLGIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPER
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 VELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLA
::::::: :::::.:.::::::: :.::..::::::: :.::.:.::: ::::::.:::.
CCDS12 VELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 SRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPV
:: ::: ::::::::..:::: :: ::::: ::.:::::.:::.::.:: :::.:. :
CCDS12 RRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 DCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLG
:.::::::.:::::.:::::: :: :: .:...: :.... :..::.....: : ::
CCDS12 VCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 GERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQ
.. .:. ...:..:: .: : :..: . ::. :::.: : :..:::.:::: : ::
CCDS12 NQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 LQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRH
: :.:: :.:::: ::::::: :...:.:.. .:::::::..:. :: . : .....
CCDS12 LLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQ
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 VLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDI
. .::: ::: :::.:::.:. .:.: :. .::: :.: :..:. : :....
CCDS12 TPMCQAWGNPLPELKCLKDGTF-PLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNV
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 EAGSSHFVPVFVAVLLTLGVVTIVLALM----YVFREHQRSGSYHVREESTYLPLTSMQP
. : . :..:. ....... :.. .... .:.... . :.
CCDS12 ------LSPRYEIVIITVVAAAVIMGTAGLSTYLYNRQRKIKKYRLQQAQKGTPMKPNTQ
480 490 500 510 520
540
pF1KB5 TEAMGEEPSRAE
CCDS12 ATPP
530
>>CCDS11657.1 ICAM2 gene_id:3384|Hs108|chr17 (275 aa)
initn: 428 init1: 302 opt: 419 Z-score: 452.5 bits: 92.5 E(32554): 6.9e-19
Smith-Waterman score: 419; 36.0% identity (63.1% similar) in 214 aa overlap (18-226:16-225)
10 20 30 40 50 60
pF1KB5 MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSS
:.:: :: . . : ..:.:.. .. ::: ::::: : .
CCDS11 MSSFGYRTLTVALFTLICC---PGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQP
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 EKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERV
: .:::::.: :. : . .::.. .. . : :.:.: . .::..::. :..:
CCDS11 EVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQV
60 70 80 90 100 110
130 140 150 160 170
pF1KB5 ELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQP---AVEEPAEVTATV
:. : ::..::..:.: : :::. :.: .: : . :. : :.:::
CCDS11 ILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 --LASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVET
:.:.: ::: . ::.. .: ..: . :::..:. . ::. ..:
CCDS11 NSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMVIIVTVVSVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 SWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCN
CCDS11 LSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
240 250 260 270
547 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:37:46 2016 done: Fri Nov 4 21:37:47 2016
Total Scan time: 3.070 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]