FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5959, 513 aa 1>>>pF1KB5959 513 - 513 aa - 513 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8676+/-0.000323; mu= -0.6894+/- 0.020 mean_var=254.3199+/-52.518, 0's: 0 Z-trim(124.1): 2 B-trim: 685 in 1/57 Lambda= 0.080424 statistics sampled from 45180 (45182) to 45180 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.53), width: 16 Scan time: 10.880 The best scores are: opt bits E(85289) NP_061130 (OMIM: 609494) zinc finger protein 395 [ ( 513) 3560 425.7 1.5e-118 NP_064446 (OMIM: 609493) SLC2A4 regulator [Homo sa ( 387) 281 45.2 0.00042 >>NP_061130 (OMIM: 609494) zinc finger protein 395 [Homo (513 aa) initn: 3560 init1: 3560 opt: 3560 Z-score: 2249.1 bits: 425.7 E(85289): 1.5e-118 Smith-Waterman score: 3560; 100.0% identity (100.0% similar) in 513 aa overlap (1-513:1-513) 10 20 30 40 50 60 pF1KB5 MASVLSRRLGKRSLLGARVLGPSASEGPSAAPPSEPLLEGAAPQPFTTSDDTPCQEQPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MASVLSRRLGKRSLLGARVLGPSASEGPSAAPPSEPLLEGAAPQPFTTSDDTPCQEQPKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VLKAPSTSGLQQVAFQPGQKVYVWYGGQECTGLVEQHSWMEGQVTVWLLEQKLQVCCRVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VLKAPSTSGLQQVAFQPGQKVYVWYGGQECTGLVEQHSWMEGQVTVWLLEQKLQVCCRVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 EVWLAELQGPCPQAPPLEPGAQALAYRPVSRNIDVPKRKSDAVEMDEMMAAMVLTSLSCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EVWLAELQGPCPQAPPLEPGAQALAYRPVSRNIDVPKRKSDAVEMDEMMAAMVLTSLSCS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PVVQSPPGTEANFSASRAACDPWKESGDISDSGSSTTSGHWSGSSGVSTPSPPHPQASPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PVVQSPPGTEANFSASRAACDPWKESGDISDSGSSTTSGHWSGSSGVSTPSPPHPQASPK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YLGDAFGSPQTDHGFETDPDPFLLDEPAPRKRKNSVKVMYKCLWPNCGKVLRSIVGIKRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 YLGDAFGSPQTDHGFETDPDPFLLDEPAPRKRKNSVKVMYKCLWPNCGKVLRSIVGIKRH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VKALHLGDTVDSDQFKREEDFYYTEVQLKEESAAAAAAAAAGTPVPGTPTSEPAPTPSMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VKALHLGDTVDSDQFKREEDFYYTEVQLKEESAAAAAAAAAGTPVPGTPTSEPAPTPSMT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GLPLSALPPPLHKAQSSGPEHPGPESSLPSGALSKSAPGSFWHIQADHAYQALPSFQIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 GLPLSALPPPLHKAQSSGPEHPGPESSLPSGALSKSAPGSFWHIQADHAYQALPSFQIPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 SPHIYTSVSWAAAPSAACSLSPVRSRSLSFSEPQQPAPAMKSHLIVTSPPRAQSGARKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SPHIYTSVSWAAAPSAACSLSPVRSRSLSFSEPQQPAPAMKSHLIVTSPPRAQSGARKAR 430 440 450 460 470 480 490 500 510 pF1KB5 GEAKKCRKVYGIEHRDQWCTACRWKKACQRFLD ::::::::::::::::::::::::::::::::: NP_061 GEAKKCRKVYGIEHRDQWCTACRWKKACQRFLD 490 500 510 >>NP_064446 (OMIM: 609493) SLC2A4 regulator [Homo sapien (387 aa) initn: 596 init1: 252 opt: 281 Z-score: 194.7 bits: 45.2 E(85289): 0.00042 Smith-Waterman score: 632; 36.9% identity (54.6% similar) in 390 aa overlap (134-513:70-387) 110 120 130 140 150 160 pF1KB5 VTVWLLEQKLQVCCRVEEVWLAELQGPCPQAPPLEPGAQALAYRPVSRNIDVPKRKSDA- :: :: : : : .: :: ... NP_064 PPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTP-SAHIPVPAQRATPG 40 50 60 70 80 90 170 180 190 200 210 pF1KB5 -VEMDEMMAAMVLTSLSCSPVVQSPPGTEANFSASRAACDPWKESGDISDSGS---STTS ...::.::: .::::: ::.. . : : :: . . .::::. . :: :..: NP_064 KARLDEVMAAAALTSLSTSPLLLGAP--VAAFSP-EPGLEPWKEAL-VRPPGSYSSSSNS 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 GHW-----SGSSGVSTPSPPHPQASPKYLGDAFGSPQTDHGFETDPDPFLLDEPAPRKRK : : : .:. :::::: : :.. : ::. ::. :::: NP_064 GDWGWDLASDQSSPSTPSPPLP-------------PEAAH--------FLFGEPTLRKRK 160 170 180 190 280 290 300 310 320 330 pF1KB5 NSVKVMYKCLWPNCGKVLRSIVGIKRHVKALHLGDTVDSDQFKREEDFYYTEVQLKEESA . ..::..::: .::::: . ...::.. .::: .. .: ::::::::... .. NP_064 SPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTL 200 210 220 230 240 250 340 350 360 370 380 390 pF1KB5 AAAAAAAAGTPVPGTPTSEPAPTPSMTGLPLSALPPPLHKAQSSGPEHPGPESSLPSGAL . . .. ::: : . :: : . :: : :: . : : : : .: NP_064 TDGLSSL--TPVSPTASMPPA-FPRLE-LP-ELLEPPALPSPLRPPAPPLP----PPPVL 260 270 280 290 300 400 410 420 430 440 450 pF1KB5 SKSAPGSFWHIQADHAYQALPSFQIPVSPHIYTSVSWAAAPSAACSLSPVRSRSLSFSEP : : . : .:..::. : :.:.: . NP_064 STVANPQSCH--SDRVYQG-------------------------C-LTPARLEPQPTEVG 310 320 330 460 470 480 490 500 510 pF1KB5 QQPAPAMKSHLIVTSPPRAQSGARKARGEAKKCRKVYGIEHRDQWCTACRWKKACQRFLD : ::..:.. :: :: ::.:::::::::.:.:: :::::::::::::::: NP_064 ACP-PALSSRIGVT--------LRKPRGDAKKCRKVYGMERRDLWCTACRWKKACQRFLD 340 350 360 370 380 513 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:46:41 2016 done: Sat Nov 5 10:46:43 2016 Total Scan time: 10.880 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]