FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5961, 515 aa 1>>>pF1KB5961 515 - 515 aa - 515 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4794+/-0.000896; mu= 17.6910+/- 0.054 mean_var=73.4503+/-14.545, 0's: 0 Z-trim(106.6): 60 B-trim: 33 in 1/49 Lambda= 0.149650 statistics sampled from 9004 (9064) to 9004 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.278), width: 16 Scan time: 2.910 The best scores are: opt bits E(32554) CCDS1895.1 GMCL1 gene_id:64395|Hs108|chr2 ( 515) 3463 757.1 1e-218 CCDS3245.2 KLHL6 gene_id:89857|Hs108|chr3 ( 621) 280 70.0 8.9e-12 >>CCDS1895.1 GMCL1 gene_id:64395|Hs108|chr2 (515 aa) initn: 3463 init1: 3463 opt: 3463 Z-score: 4040.1 bits: 757.1 E(32554): 1e-218 Smith-Waterman score: 3463; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KB5 MGSLSSRVLRQPRPALAQQAQGARAGGSARRPDTGDDAAGHGFCYCAGSHKRKRSSGSFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MGSLSSRVLRQPRPALAQQAQGARAGGSARRPDTGDDAAGHGFCYCAGSHKRKRSSGSFC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 YCHPDSETDEDEEEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 YCHPDSETDEDEEEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDVEALQVAFGSLYRDDVLIKPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 LHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDVEALQVAFGSLYRDDVLIKPSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VVAILAAACLLQLDGLIQQCGETMKETVNVKTVCGYYTSAGTYGLDSVKKKCLEWLLNNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 VVAILAAACLLQLDGLIQQCGETMKETVNVKTVCGYYTSAGTYGLDSVKKKCLEWLLNNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MTHQNVELFKELSINVMKQLIGSSNLFVMQVEMDIYTALKKWMFLQLVPSWNGSLKQLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MTHQNVELFKELSINVMKQLIGSSNLFVMQVEMDIYTALKKWMFLQLVPSWNGSLKQLLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ETDVWFSKQRKDFEGMAFLETEQGKPFVSVFRHLRLQYIISDLASARIIEQDAVVPSEWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 ETDVWFSKQRKDFEGMAFLETEQGKPFVSVFRHLRLQYIISDLASARIIEQDAVVPSEWL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SSVYKQQWFAMLRAEQDSEVGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 SSVYKQQWFAMLRAEQDSEVGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRTTGYQILTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 LVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRTTGYQILTL 430 440 450 460 470 480 490 500 510 pF1KB5 EKDQEQVVMNLDSRLLIFPLYICCNFLYISPEKKN ::::::::::::::::::::::::::::::::::: CCDS18 EKDQEQVVMNLDSRLLIFPLYICCNFLYISPEKKN 490 500 510 >>CCDS3245.2 KLHL6 gene_id:89857|Hs108|chr3 (621 aa) initn: 75 init1: 45 opt: 280 Z-score: 324.9 bits: 70.0 E(32554): 8.9e-12 Smith-Waterman score: 280; 25.8% identity (61.5% similar) in 221 aa overlap (68-283:28-243) 40 50 60 70 80 90 pF1KB5 AAGHGFCYCAGSHKRKRSSGSFCYCHPDSETDEDEEEGDEQQRLLNTPRRKKLKSTSKYI ::: .. . ..:: . : . . : CCDS32 MLMAGQRGAWTMGDVVEKSLEGPLAPSTDEPSQKTGDLVEILNGEKVKFDDAGLSLI 10 20 30 40 50 100 110 120 130 140 150 pF1KB5 YQ----TLFLNGENSDIKICALGEEWSLHKIYLCQ-SGYFSSMFSGSWKESSMNIIELEI : :: ... .:. .:. .:.: :.. : :.:: .:: .. ::. : .: CCDS32 LQNGLETLRMENALTDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEK----YEKRI 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB5 PDQNIDVEALQVAFGSLYRDDVLIKPSRVVAILAAACLLQLDGLIQQCGETMKETVNVKT ...:.:.... . : . .:: . : .: :: :.:. ... :. . :..: .. CCDS32 IIKGVDAETMHTLLDYTYTSKALITKQNVQRVLEAANLFQFLRMVDACASFLTEALNPEN 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB5 VCGYYTSAGTYGLDSVKKKCLEWLLNNLMTHQNVELFKELSINVMKQLIGSSNLFVMQVE : : :..:::.::. ....:.. : : : .: ........ :..:.: . : CCDS32 CVGILRLADTHSLDSLKKQVQSYIIQNFVQILNSEEFLDLPVDTLHHILKSDDLYVTE-E 180 190 200 210 220 230 280 290 300 310 320 330 pF1KB5 MDIYTALKKWMFLQLVPSWNGSLKQLLTETDVWFSKQRKDFEGMAFLETEQGKPFVSVFR ... .. .:. CCDS32 AQVFETVMSWVRHKPSERLCLLPYVLENVRLPLLDPWYFVETVEADPLIRQCPEVFPLLQ 240 250 260 270 280 290 515 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:10:12 2016 done: Sat Nov 5 18:10:13 2016 Total Scan time: 2.910 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]