FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5973, 519 aa 1>>>pF1KB5973 519 - 519 aa - 519 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8041+/-0.000833; mu= 9.2423+/- 0.051 mean_var=182.4933+/-37.567, 0's: 0 Z-trim(113.9): 55 B-trim: 696 in 1/51 Lambda= 0.094940 statistics sampled from 14454 (14508) to 14454 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.446), width: 16 Scan time: 3.640 The best scores are: opt bits E(32554) CCDS3867.1 IRX4 gene_id:50805|Hs108|chr5 ( 519) 3501 491.6 8.9e-139 CCDS75225.1 IRX4 gene_id:50805|Hs108|chr5 ( 545) 2589 366.7 3.7e-101 CCDS32449.1 IRX6 gene_id:79190|Hs108|chr16 ( 446) 876 132.0 1.4e-30 CCDS10750.1 IRX3 gene_id:79191|Hs108|chr16 ( 501) 703 108.4 2e-23 CCDS10751.1 IRX5 gene_id:10265|Hs108|chr16 ( 483) 702 108.2 2.2e-23 CCDS58462.1 IRX5 gene_id:10265|Hs108|chr16 ( 482) 694 107.1 4.6e-23 CCDS3868.1 IRX2 gene_id:153572|Hs108|chr5 ( 471) 568 89.9 7.1e-18 CCDS34132.1 IRX1 gene_id:79192|Hs108|chr5 ( 480) 564 89.3 1.1e-17 >>CCDS3867.1 IRX4 gene_id:50805|Hs108|chr5 (519 aa) initn: 3501 init1: 3501 opt: 3501 Z-score: 2604.9 bits: 491.6 E(32554): 8.9e-139 Smith-Waterman score: 3501; 100.0% identity (100.0% similar) in 519 aa overlap (1-519:1-519) 10 20 30 40 50 60 pF1KB5 MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 RHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 AYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 AYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 ITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 SSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 SGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 GLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 SGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 SGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANV 430 440 450 460 470 480 490 500 510 pF1KB5 LTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA ::::::::::::::::::::::::::::::::::::::: CCDS38 LTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA 490 500 510 >>CCDS75225.1 IRX4 gene_id:50805|Hs108|chr5 (545 aa) initn: 2589 init1: 2589 opt: 2589 Z-score: 1929.6 bits: 366.7 E(32554): 3.7e-101 Smith-Waterman score: 3439; 95.2% identity (95.2% similar) in 545 aa overlap (1-519:1-545) 10 20 30 40 50 60 pF1KB5 MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 RHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAA 70 80 90 100 110 120 130 140 150 pF1KB5 AYYPYEPALGQYPYDR--------------------------YGTMDSGTRRKNATRETT :::::::::::::::: :::::::::::::::::: CCDS75 AYYPYEPALGQYPYDRIKRLGGHPHKGIGLDLSGLGRSPGSLYGTMDSGTRRKNATRETT 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 STLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 STLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKC 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB5 ADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACE 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB5 LKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGP 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB5 EPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCM 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB5 LKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLN 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB5 QAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGG 490 500 510 520 530 540 pF1KB5 KPFCA ::::: CCDS75 KPFCA >>CCDS32449.1 IRX6 gene_id:79190|Hs108|chr16 (446 aa) initn: 765 init1: 452 opt: 876 Z-score: 662.7 bits: 132.0 E(32554): 1.4e-30 Smith-Waterman score: 973; 44.1% identity (66.4% similar) in 440 aa overlap (1-431:1-407) 10 20 30 40 50 60 pF1KB5 MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA ::.:.::.:: .: ::: ...: .::::: :...: . ... . : :.::::..: CCDS32 MSFPHFGHPYRGASQFLASASSSTTCCESTQRSVSDVASGSTPAPALCCAPYDSRLLGSA 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 RHELNSAAALGVYGGPYGGS---QGYGNYVTYGSEASAFY-SLN-SFDSKDGSGSAHGGL : :: .::::.::.::... :.: .:. :. : ..: .:: ... :...:: ..: CCDS32 RPEL--GAALGIYGAPYAAAAAAQSYPGYLPYSPEPPSLYGALNPQYEFKEAAGSFTSSL 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 APAAAAYYPYEPALGQYPYDRYGTMD-SGT-RRKNATRETTSTLKAWLQEHRKNPYPTKG : .: ::::: .:::: :.:::... ::. :::::::::::::::::.::::::::::: CCDS32 AQPGA-YYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 EKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEE ::::::::::::::::::::::::::::::::::: :.:: ..:.. :::::. CCDS32 EKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKA-------EGGEED 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAP . ..:.. ...: . :.::::.:.. : : : . : : .: CCDS32 SLGCLTADTKEVT-ASQEARGLRLSDLEDLEEEEEEEEEAEDE----------EVVATAG 240 250 260 270 300 310 320 330 340 350 pF1KB5 DGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGF : .. .:: .:: . .:: . ::: : : .: :.. . :. : CCDS32 DRLTEFRKGA--QSLPGPCAAAREGRLER-RECGLAAPRFSFNDPSGSEEADFLSAETGS 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB5 VPAGASAGLEAKPRIWSLAHTATAAAA--AATSLSQTEFPSCMLKRQGPAAPAAVSSAPA :::::::::::::.:. : . . . : : :. :. : :: CCDS32 PRLTMHYPCLEKPRIWSLAHTATASAVEGAPPARPRPRSPEC---RMIPGQP------PA 340 350 360 370 380 420 430 440 450 460 470 pF1KB5 TSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLG .. ...:...: :. . : CCDS32 SARRLSVPRDSACDESSCIPKAFGNPKFALQGLPLNCAPCPRRSEPVVQCQYPSGAEAG 390 400 410 420 430 440 >>CCDS10750.1 IRX3 gene_id:79191|Hs108|chr16 (501 aa) initn: 654 init1: 473 opt: 703 Z-score: 533.9 bits: 108.4 E(32554): 2e-23 Smith-Waterman score: 739; 36.7% identity (56.9% similar) in 534 aa overlap (1-519:1-465) 10 20 30 40 50 60 pF1KB5 MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA ::.::.:: : : :. .. .. ::: . : .: .:.: :.: :.. CCDS10 MSFPQLGYQYIR-P--LYPSERPGAAGGSGGSAGARGGLGAGA----------SELNASG 10 20 30 40 70 80 90 100 110 pF1KB5 RHELNSAAALGVYGGPYGGS------QGYGNYVTYGSEASAFYSLNS-FDSKDGSGSAHG :... . .:::.::... :::: .. :..: : .:.. .. ::. : : CCDS10 --SLSNVLS-SVYGAPYAAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYELKDSPGVQH- 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 GLAPAAAAYYPY-EPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTK ::::: .:. .::. ::: .: : .: ::::::.::::::::.:::::::::: CCDS10 ---PAAAAAFPHPHPAF--YPYGQYQFGDP-SRPKNATRESTSTLKAWLNEHRKNPYPTK 110 120 130 140 150 180 190 200 210 220 230 pF1KB5 GEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEE :::::::::::::::::::::::::::::::::::: ::.. .: :. .::: :: CCDS10 GEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEE 160 170 180 190 200 210 240 250 260 270 280 pF1KB5 EAREEPLKSSKNAEPVGKEEKELE---LSDLDDFDPLEAEPPACELKPPFHSLDGGLERV . .. . . : .: ::.. :.: :. . .. : : :: :. .: CCDS10 DEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRD 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB5 PAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEA ::.... . : . .. .: :: : : : : : : : ..:.. CCDS10 GDLGLGPISDS----KNSDSEDSSEGL-ED--RPLPVLSLA---PAPPPVAVASPSLPSP 280 290 300 310 320 350 360 370 380 390 400 pF1KB5 KLGF---VPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPA-APAA ... .:: : :. ::.:::::.:::. : :. . : : ::.: CCDS10 PVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRS-----PPGAGGSPPGAAVAPSA 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB5 VSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALL .. .::.. ..: : : ..:. .. :.. : : : : CCDS10 LQLSPAAAAAAA--H-----RLVSAPLGKFPAWTNRPFPGP-------------PPGPRL 390 400 410 420 470 480 490 500 510 pF1KB5 DPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA : : ::.. : ..: :. . : ::. :: : :. :: :. CCDS10 HPLSL---LGSAP-----PHLLGLPGAAGHPAAAAAFARP--AEPE-GGTDRCSALEVEK 430 440 450 460 470 CCDS10 KLLKTAFQPVPRRPQNHLDAALVLSALSSS 480 490 500 >>CCDS10751.1 IRX5 gene_id:10265|Hs108|chr16 (483 aa) initn: 562 init1: 451 opt: 702 Z-score: 533.4 bits: 108.2 E(32554): 2.2e-23 Smith-Waterman score: 702; 38.9% identity (59.4% similar) in 406 aa overlap (39-422:11-394) 10 20 30 40 50 60 pF1KB5 PYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAA :.:: : ::.: . ... : . . . CCDS10 MSYPQGYLYQPSASL-ALYSCPAYSTSVISGPRTDELGRS 10 20 30 70 80 90 100 110 120 pF1KB5 ALGVYGGPYGGSQ-------GYGNYVTYGSEASAFYSLNSFDSKDGSGSAHG-GLAPAAA . : .::.:: ::.... ::.. .: . .:.: :: : :.: .. CCDS10 SSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAA-AAAAAFSSYVGSPYDHTPGMA-GSL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 AYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAI .:.:: ::.::: . . ::::::..:.::::::.:::::::::::::::::: CCDS10 GYHPYAAPLGSYPY------GDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAI 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 ITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLK :::::::::::::::::::::::::::: :::. :: : ::. :.. ..:: : CCDS10 ITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDE-----EEEENIDLEKNDEDEPQK 160 170 180 190 200 250 260 270 280 290 pF1KB5 SSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSL-DGGLERVPAAPDGPVKE ...: : : : . . . :.. ::. : :: :. ... :. .: . CCDS10 PEDKGDPEGPEAGGAEQKAASGCERLQG-PPTPAGKETEGSLSDSDFKEPPS--EGRLDA 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 ASGALRMS--LAAGGGAA-LDEDLERARSCLRSAAAGPEP----LPGAEGGPQVCEAKLG .: : . :: .:: : :: . . : ::.: .: . :::.: .. CCDS10 LQGPPRTGGPSPAGPAAARLAED-PAPHYPAGAPAPGPHPAAGEVPPGPGGPSVIHSP-- 270 280 290 300 310 320 360 370 380 390 400 pF1KB5 FVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTE---FPSCMLKRQGPA---APAAV : .. :::..::::. ::.. . . . .: : : : : . :. CCDS10 --PPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGNEGSPCPPCPGPIAGQALGGSRASP 330 340 350 360 370 410 420 430 440 450 460 pF1KB5 SSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLD . ::. :::. : : CCDS10 APAPSRSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPGPTTGPGSH 380 390 400 410 420 430 >>CCDS58462.1 IRX5 gene_id:10265|Hs108|chr16 (482 aa) initn: 547 init1: 436 opt: 694 Z-score: 527.5 bits: 107.1 E(32554): 4.6e-23 Smith-Waterman score: 694; 38.9% identity (59.4% similar) in 406 aa overlap (39-422:11-393) 10 20 30 40 50 60 pF1KB5 PYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAA :.:: : ::.: . ... : . . . CCDS58 MSYPQGYLYQPSASL-ALYSCPAYSTSVISGPRTDELGRS 10 20 30 70 80 90 100 110 120 pF1KB5 ALGVYGGPYGGSQ-------GYGNYVTYGSEASAFYSLNSFDSKDGSGSAHG-GLAPAAA . : .::.:: ::.... ::.. .: . .:.: :: : :.: .. CCDS58 SSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAA-AAAAAFSSYVGSPYDHTPGMA-GSL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 AYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAI .:.:: ::.::: . . ::::::..:.::::::.:::::::::::::::::: CCDS58 GYHPYAAPLGSYPY------GDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAI 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 ITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLK :::::::::::::::::::::::::::: :::. :: : ::. :.. ..:: : CCDS58 ITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDE-----EEEENIDLEKNDEDEPQK 160 170 180 190 200 250 260 270 280 290 pF1KB5 SSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSL-DGGLERVPAAPDGPVKE ...: : : : . . . :.. ::. : :: :. ... :. .: . CCDS58 PEDKGDPEGPEAGA-EQKAASGCERLQG-PPTPAGKETEGSLSDSDFKEPPS--EGRLDA 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 ASGALRMS--LAAGGGAA-LDEDLERARSCLRSAAAGPEP----LPGAEGGPQVCEAKLG .: : . :: .:: : :: . . : ::.: .: . :::.: .. CCDS58 LQGPPRTGGPSPAGPAAARLAED-PAPHYPAGAPAPGPHPAAGEVPPGPGGPSVIHSP-- 270 280 290 300 310 360 370 380 390 400 pF1KB5 FVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTE---FPSCMLKRQGPA---APAAV : .. :::..::::. ::.. . . . .: : : : : . :. CCDS58 --PPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGNEGSPCPPCPGPIAGQALGGSRASP 320 330 340 350 360 370 410 420 430 440 450 460 pF1KB5 SSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLD . ::. :::. : : CCDS58 APAPSRSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPGPTTGPGSH 380 390 400 410 420 430 >>CCDS3868.1 IRX2 gene_id:153572|Hs108|chr5 (471 aa) initn: 554 init1: 443 opt: 568 Z-score: 434.4 bits: 89.9 E(32554): 7.1e-18 Smith-Waterman score: 638; 36.8% identity (55.7% similar) in 476 aa overlap (40-481:11-439) 10 20 30 40 50 60 pF1KB5 YSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAA : .. : ::.: . ::. : : . .: CCDS38 MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSA 10 20 30 40 70 80 90 100 110 120 pF1KB5 LGVYGGPYGGSQ--------GYGNYVTYGSEASAFYSLNSFDSKDGSG-SAHGGLAPAAA : .:: :: :.:. . :...:.: . .: : :. .:: .: CCDS38 SGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAA--AAAGFPSYMGAPYDAHTTGMTGAI 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 AYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAI .:.:: : :::. ... . ::::::..:.::::::.:::::::::::::::::: CCDS38 SYHPYGSA--AYPYQ----LNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAI 100 110 120 130 140 150 190 200 210 220 230 pF1KB5 ITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREE-PL :::::::::::::::::::::::::::: :::: :: .:.:: ....: : CCDS38 ITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDE-------DEDEGDATRSKDESPD 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 KSSKNAEPVGKEEK-ELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVK :.....: ...: :....: : .: . :: :..: :. CCDS38 KAQEGTETSAEDEGISLHVDSLTDH--------SCSAES-----DG--EKLPCRAGDPLC 210 220 230 240 250 300 310 320 330 340 350 pF1KB5 EASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEG---GPQVCEAKLGF-- : ::. . :.: : :. . :: : :. .: : : CCDS38 E-SGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRK 260 270 280 290 300 360 370 380 390 400 pF1KB5 VPAGA--SAGLE---AKPRIWSLAHTATAAAAAATSLSQTEF-PSCMLKRQGP------A .: :. : : .::..::::. :: ..:.: . :.: :: : CCDS38 TPQGSRTSPGAPPPASKPKLWSLAEIAT------SDLKQPSLGPGC-----GPPGLPAAA 310 320 330 340 350 410 420 430 440 450 pF1KB5 APAAVSSAPATSPSVALPHSGALDRHQDSPV----TSLRNWVDGVFHDPILRHSTLNQAW :::.... :. :: : : : . :: :. : .. . .::. :.: CCDS38 APASTGAPPGGSPYPASPLLGR-PLYYTSPFYGNYTNYGNLNAALQGQGLLRY---NSA- 360 370 380 390 400 410 460 470 480 490 500 510 pF1KB5 ATAKGALLDPGPLGRSLG--AGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGK :.: : : .: . : . :::. : CCDS38 AAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL 420 430 440 450 460 470 >>CCDS34132.1 IRX1 gene_id:79192|Hs108|chr5 (480 aa) initn: 552 init1: 416 opt: 564 Z-score: 431.3 bits: 89.3 E(32554): 1.1e-17 Smith-Waterman score: 687; 36.3% identity (56.8% similar) in 512 aa overlap (1-502:1-422) 10 20 30 40 50 60 pF1KB5 MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA ::.::.::: :.: :.. . : : .:: .. ::.: . . : :. . CCDS34 MSFPQLGYP-----QYLSAAGPGAYGGERPG-VLAAAAAAAAAASSGRPGAAE---LGGG 10 20 30 40 50 70 80 90 100 110 pF1KB5 RHELNSAAALGVYG--GPYGGSQGYGNYVTYGSEASAFYSLNS-FDSKDGSGSAHGGLAP ...::.:. :::.:. .:. .. :... : : ...: .. ::. : . .: CCDS34 AGAAAVTSVLGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 -AAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKI .: ::::: ::. .:: : : : ::::::.::::::::.:::::::::::::: CCDS34 HTAPAYYPY----GQF---QYG--DPG-RPKNATRESTSTLKAWLNEHRKNPYPTKGEKI 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 MLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEARE :::::::::::::::::::::::::::::.:: :.: :.. : . :: :.:.. CCDS34 MLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSK--DQEDGALFGSDTEGDPEKAED 170 180 190 200 210 240 250 260 270 280 290 pF1KB5 EPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGP . . .. . .:.. . :. :: : .:: : :. ::::.. CCDS34 DEEIDLESIDIDKIDEHDGDQSNEDDED--KAEAP--------HA--------PAAPSAL 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 VKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPA ... .. : :: : :. : : : .::: :. .. . :. CCDS34 ARDQGSPL---------AAADV-LKPQDSPLGLAKEAPEP-----GSTRL------LSPG 270 280 290 300 360 370 380 390 400 410 pF1KB5 GASAGLEA----KPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPAT .:..::.. ::.:::::.:::. .: .. :. .::.: .:: CCDS34 AAAGGLQGAPHGKPKIWSLAETATSPDGAPK--ASPPPPAGHPGAHGPSA-----GAPLQ 310 320 330 340 350 420 430 440 450 460 470 pF1KB5 SPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGR :. :: : : . .. ::....: :.:.::. . CCDS34 HPAF-LPSHGLYTCH----IGKFSNWTNSAF---------------LAQGSLLN---MRS 360 370 380 390 480 490 500 510 pF1KB5 SLGAGA--NVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA ::.:: . .: : :: : : : :: CCDS34 FLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERDLVPRPDSPAQ 400 410 420 430 440 450 CCDS34 QLKSPFQPVRDNSLAPQEGTPRILAALPSA 460 470 480 519 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:49:15 2016 done: Sat Nov 5 10:49:16 2016 Total Scan time: 3.640 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]