FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5974, 560 aa 1>>>pF1KB5974 560 - 560 aa - 560 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0226+/-0.00103; mu= 2.1702+/- 0.062 mean_var=216.3222+/-44.160, 0's: 0 Z-trim(110.4): 79 B-trim: 23 in 1/51 Lambda= 0.087201 statistics sampled from 11547 (11616) to 11547 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.357), width: 16 Scan time: 3.630 The best scores are: opt bits E(32554) CCDS46534.1 AGFG1 gene_id:3267|Hs108|chr2 ( 560) 3682 476.3 4.1e-134 CCDS2467.1 AGFG1 gene_id:3267|Hs108|chr2 ( 562) 3668 474.6 1.4e-133 CCDS46533.1 AGFG1 gene_id:3267|Hs108|chr2 ( 584) 1922 254.9 1.9e-67 CCDS46535.1 AGFG1 gene_id:3267|Hs108|chr2 ( 522) 1778 236.8 5e-62 CCDS5697.1 AGFG2 gene_id:3268|Hs108|chr7 ( 481) 908 127.3 4.2e-29 >>CCDS46534.1 AGFG1 gene_id:3267|Hs108|chr2 (560 aa) initn: 3682 init1: 3682 opt: 3682 Z-score: 2521.2 bits: 476.3 E(32554): 4.1e-134 Smith-Waterman score: 3682; 100.0% identity (100.0% similar) in 560 aa overlap (1-560:1-560) 10 20 30 40 50 60 pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPF 490 500 510 520 530 540 550 560 pF1KB5 MTGAPTGQFPTGSSSTNPFL :::::::::::::::::::: CCDS46 MTGAPTGQFPTGSSSTNPFL 550 560 >>CCDS2467.1 AGFG1 gene_id:3267|Hs108|chr2 (562 aa) initn: 3368 init1: 3368 opt: 3668 Z-score: 2511.6 bits: 474.6 E(32554): 1.4e-133 Smith-Waterman score: 3668; 99.6% identity (99.6% similar) in 562 aa overlap (1-560:1-562) 10 20 30 40 50 60 pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNG--FAAFGQTKPVVTPFGQVAAAGVSSN ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: CCDS24 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSN 490 500 510 520 530 540 540 550 560 pF1KB5 PFMTGAPTGQFPTGSSSTNPFL :::::::::::::::::::::: CCDS24 PFMTGAPTGQFPTGSSSTNPFL 550 560 >>CCDS46533.1 AGFG1 gene_id:3267|Hs108|chr2 (584 aa) initn: 1980 init1: 1850 opt: 1922 Z-score: 1324.3 bits: 254.9 E(32554): 1.9e-67 Smith-Waterman score: 3616; 95.7% identity (95.9% similar) in 584 aa overlap (1-560:1-584) 10 20 30 40 50 60 pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 190 200 210 220 230 240 250 260 270 pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTG------------------------GSAA :::::::::::::::::::::::::::::::. :::: CCDS46 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB5 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB5 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB5 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB5 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA 490 500 510 520 530 540 520 530 540 550 560 pF1KB5 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL :::::::::::::::::::::::::::::::::::::::::::: CCDS46 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 550 560 570 580 >>CCDS46535.1 AGFG1 gene_id:3267|Hs108|chr2 (522 aa) initn: 2012 init1: 1563 opt: 1778 Z-score: 1227.0 bits: 236.8 E(32554): 5e-62 Smith-Waterman score: 3306; 92.5% identity (92.5% similar) in 562 aa overlap (1-560:1-522) 10 20 30 40 50 60 pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHA--------- 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN ::::::::::::::::::::::::::::: CCDS46 -------------------------------GGSAASVNANFAHFDNFPKSSSADFGTFN 240 250 260 310 320 330 340 350 360 pF1KB5 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB5 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB5 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY 390 400 410 420 430 440 490 500 510 520 530 pF1KB5 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNG--FAAFGQTKPVVTPFGQVAAAGVSSN ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: CCDS46 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSN 450 460 470 480 490 500 540 550 560 pF1KB5 PFMTGAPTGQFPTGSSSTNPFL :::::::::::::::::::::: CCDS46 PFMTGAPTGQFPTGSSSTNPFL 510 520 >>CCDS5697.1 AGFG2 gene_id:3268|Hs108|chr7 (481 aa) initn: 988 init1: 635 opt: 908 Z-score: 636.0 bits: 127.3 E(32554): 4.2e-29 Smith-Waterman score: 1021; 39.7% identity (59.1% similar) in 562 aa overlap (15-560:31-481) 10 20 30 40 pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPH--NRKCFDCDQRGPTYVNM . .:.. : . ::.::.: ::: :::.. CCDS56 MVMAAKKGPGPGGGVSGGKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 TVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSS ::::::::.::: :::::::::::::::::::. :. :::..:::::..::::::: :.: CCDS56 TVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRGNEVCRKIWLGLFDARTS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB5 AIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKS .:: :::::::::::::::::::::::.:.: . ...: .:. .: :: :::.. CCDS56 LVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGS---ASTPVQGSIPEGKPLRT 130 140 150 160 170 170 180 190 200 210 pF1KB5 LLGDSAPTLHLNKGTPSQSPV----VGRSQGQQQE--------KKQFDLLSDLGSDIFAA :::: ::.: . .: :: :: . ::... . : . :::.:.:.: ::: CCDS56 LLGDPAPSLSVAASTSSQ-PVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAA 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 PAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSPFQPQT : . : : :: : . ..:. ... :::::::... .:: ::..: :... :: : CCDS56 P---QMAPA----FAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQP 240 250 260 270 280 280 290 300 310 320 330 pF1KB5 TGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAAL : : .:: CCDS56 T-----------------PAGSS------------------------------------- 290 340 350 360 370 380 390 pF1KB5 ANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATS ::. ::.: :: .: :. .::.. : .. .. . CCDS56 --------------QGTPFGATPLAP----ASQPN----------SLADVGSFLGPGVPA 300 310 320 400 410 420 430 440 pF1KB5 SNAYTSTSNASSNVFGTVPVVASAQTQPAS-SSVPAPFGATPSTNPFVAAAGPSVASSTN ... .: . . : :: . :. .. ::. ::: ::::.: :. : ::: CCDS56 AGVPSSLFGMA----GQVPPLQSVTMGGGGGSSTGLAFGAF--TNPFTAPAAQSPLPSTN 330 340 350 360 370 380 450 460 470 480 490 500 pF1KB5 PFQTNARGATAATFGTASMSMPTGFGTPAPYSLPT-SFSGSFQQPAFPAQAAFPQQTAFS ::: :. : . :: .: . : :: .: :: .:..:: : :: :. . :: CCDS56 PFQPNGL-APGPGFGMSSAG-P-GFPQAVP---PTGAFASSFPAPLFPPQTPLVQQ---- 390 400 410 420 430 510 520 530 540 550 560 pF1KB5 QQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL :. ..:. .:..: :..: ::.:.:::::: .. : . .::::: CCDS56 QNGSSFGDLGSAKLGQRPLSQ--PAGISTNPFMTGPSSSPFASKPPTTNPFL 440 450 460 470 480 560 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:49:54 2016 done: Sat Nov 5 10:49:54 2016 Total Scan time: 3.630 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]