FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5975, 519 aa 1>>>pF1KB5975 519 - 519 aa - 519 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3758+/-0.000407; mu= 8.9084+/- 0.025 mean_var=127.0737+/-25.071, 0's: 0 Z-trim(114.6): 132 B-trim: 33 in 1/56 Lambda= 0.113775 statistics sampled from 24339 (24471) to 24339 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.287), width: 16 Scan time: 9.480 The best scores are: opt bits E(85289) NP_149017 (OMIM: 209900,600374,615982) Bardet-Bied ( 519) 3382 566.8 5.6e-161 XP_011520150 (OMIM: 209900,600374,615982) PREDICTE ( 347) 2249 380.7 3.8e-105 XP_016877940 (OMIM: 209900,600374,615982) PREDICTE ( 347) 2249 380.7 3.8e-105 XP_016877943 (OMIM: 209900,600374,615982) PREDICTE ( 347) 2249 380.7 3.8e-105 NP_001239607 (OMIM: 209900,600374,615982) Bardet-B ( 347) 2249 380.7 3.8e-105 XP_011520151 (OMIM: 209900,600374,615982) PREDICTE ( 347) 2249 380.7 3.8e-105 XP_016877941 (OMIM: 209900,600374,615982) PREDICTE ( 347) 2249 380.7 3.8e-105 XP_016877942 (OMIM: 209900,600374,615982) PREDICTE ( 347) 2249 380.7 3.8e-105 NP_001307594 (OMIM: 209900,600374,615982) Bardet-B ( 496) 1844 314.3 5.3e-85 XP_016877939 (OMIM: 209900,600374,615982) PREDICTE ( 504) 1844 314.3 5.4e-85 XP_011520153 (OMIM: 209900,600374,615982) PREDICTE ( 275) 1797 306.5 6.8e-83 XP_006720100 (OMIM: 608132,613464,615985) PREDICTE ( 475) 265 55.1 5.4e-07 NP_938052 (OMIM: 608132,613464,615985) tetratricop ( 475) 265 55.1 5.4e-07 NP_938051 (OMIM: 608132,613464,615985) tetratricop ( 505) 265 55.1 5.7e-07 XP_006720098 (OMIM: 608132,613464,615985) PREDICTE ( 505) 265 55.1 5.7e-07 NP_653197 (OMIM: 608132,613464,615985) tetratricop ( 515) 265 55.1 5.8e-07 XP_011534736 (OMIM: 608132,613464,615985) PREDICTE ( 501) 261 54.5 8.9e-07 NP_001275710 (OMIM: 608132,613464,615985) tetratri ( 531) 261 54.5 9.3e-07 XP_011534734 (OMIM: 608132,613464,615985) PREDICTE ( 531) 261 54.5 9.3e-07 NP_001275711 (OMIM: 608132,613464,615985) tetratri ( 317) 257 53.7 9.5e-07 XP_016876467 (OMIM: 608132,613464,615985) PREDICTE ( 447) 258 54.0 1.1e-06 XP_016876466 (OMIM: 608132,613464,615985) PREDICTE ( 477) 258 54.0 1.2e-06 XP_011534735 (OMIM: 608132,613464,615985) PREDICTE ( 503) 254 53.3 2e-06 NP_001275712 (OMIM: 608132,613464,615985) tetratri ( 276) 209 45.8 0.0002 XP_011534737 (OMIM: 608132,613464,615985) PREDICTE ( 276) 209 45.8 0.0002 XP_016880977 (OMIM: 116946) PREDICTED: cell divisi ( 427) 204 45.1 0.00051 NP_858059 (OMIM: 300255) UDP-N-acetylglucosamine-- (1036) 208 45.9 0.00068 NP_858058 (OMIM: 300255) UDP-N-acetylglucosamine-- (1046) 208 45.9 0.00068 XP_016880975 (OMIM: 116946) PREDICTED: cell divisi ( 720) 204 45.2 0.00079 XP_016880974 (OMIM: 116946) PREDICTED: cell divisi ( 721) 204 45.2 0.00079 XP_011523852 (OMIM: 116946) PREDICTED: cell divisi ( 727) 204 45.2 0.00079 XP_016880973 (OMIM: 116946) PREDICTED: cell divisi ( 762) 204 45.2 0.00083 NP_001280020 (OMIM: 116946) cell division cycle pr ( 763) 204 45.2 0.00083 XP_011523851 (OMIM: 116946) PREDICTED: cell divisi ( 769) 204 45.2 0.00083 XP_011523850 (OMIM: 116946) PREDICTED: cell divisi ( 769) 204 45.2 0.00083 NP_001280018 (OMIM: 116946) cell division cycle pr ( 823) 204 45.2 0.00088 NP_001247 (OMIM: 116946) cell division cycle prote ( 824) 204 45.2 0.00088 XP_011523848 (OMIM: 116946) PREDICTED: cell divisi ( 829) 204 45.2 0.00089 NP_001107563 (OMIM: 116946) cell division cycle pr ( 830) 204 45.2 0.00089 XP_016875496 (OMIM: 615855) PREDICTED: transmembra ( 618) 198 44.2 0.0014 NP_787057 (OMIM: 615855) transmembrane and TPR rep ( 774) 198 44.2 0.0017 XP_016875494 (OMIM: 615855) PREDICTED: transmembra ( 813) 198 44.2 0.0017 XP_016875493 (OMIM: 615855) PREDICTED: transmembra ( 875) 198 44.3 0.0018 NP_001180380 (OMIM: 615855) transmembrane and TPR ( 882) 198 44.3 0.0018 XP_016875492 (OMIM: 615855) PREDICTED: transmembra ( 888) 198 44.3 0.0019 XP_005253556 (OMIM: 615855) PREDICTED: transmembra ( 944) 198 44.3 0.002 XP_016880976 (OMIM: 116946) PREDICTED: cell divisi ( 708) 188 42.6 0.0048 XP_016880972 (OMIM: 116946) PREDICTED: cell divisi ( 768) 188 42.6 0.0051 XP_016880971 (OMIM: 116946) PREDICTED: cell divisi ( 769) 188 42.6 0.0051 XP_016880970 (OMIM: 116946) PREDICTED: cell divisi ( 774) 188 42.6 0.0052 >>NP_149017 (OMIM: 209900,600374,615982) Bardet-Biedl sy (519 aa) initn: 3382 init1: 3382 opt: 3382 Z-score: 3011.1 bits: 566.8 E(85289): 5.6e-161 Smith-Waterman score: 3382; 99.8% identity (99.8% similar) in 519 aa overlap (1-519:1-519) 10 20 30 40 50 60 pF1KB5 MAEERVATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACKAVIKEQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 MAEERVATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACKAVIKEQLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 ETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 IEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 EGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 AAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRA ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_149 PFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 YAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 YAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 AQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 AQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRT 430 440 450 460 470 480 490 500 510 pF1KB5 LPSGAGGTSQFTKPPSLPLEPEPAVESSPTETSEQIREK ::::::::::::::::::::::::::::::::::::::: NP_149 LPSGAGGTSQFTKPPSLPLEPEPAVESSPTETSEQIREK 490 500 510 >>XP_011520150 (OMIM: 209900,600374,615982) PREDICTED: B (347 aa) initn: 2249 init1: 2249 opt: 2249 Z-score: 2008.6 bits: 380.7 E(85289): 3.8e-105 Smith-Waterman score: 2249; 99.7% identity (99.7% similar) in 347 aa overlap (173-519:1-347) 150 160 170 180 190 200 pF1KB5 VCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENT :::::::::::::::::::::::::::::: XP_011 MLGKIHLLEGDLDKAIEVYKKAVEFSPENT 10 20 30 210 220 230 240 250 260 pF1KB5 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 AFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRAYAEAVHLDKCNPLVNLNYAVLL ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_011 AFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE 280 290 300 310 320 330 510 pF1KB5 PAVESSPTETSEQIREK ::::::::::::::::: XP_011 PAVESSPTETSEQIREK 340 >>XP_016877940 (OMIM: 209900,600374,615982) PREDICTED: B (347 aa) initn: 2249 init1: 2249 opt: 2249 Z-score: 2008.6 bits: 380.7 E(85289): 3.8e-105 Smith-Waterman score: 2249; 99.7% identity (99.7% similar) in 347 aa overlap (173-519:1-347) 150 160 170 180 190 200 pF1KB5 VCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENT :::::::::::::::::::::::::::::: XP_016 MLGKIHLLEGDLDKAIEVYKKAVEFSPENT 10 20 30 210 220 230 240 250 260 pF1KB5 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 AFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRAYAEAVHLDKCNPLVNLNYAVLL ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_016 AFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE 280 290 300 310 320 330 510 pF1KB5 PAVESSPTETSEQIREK ::::::::::::::::: XP_016 PAVESSPTETSEQIREK 340 >>XP_016877943 (OMIM: 209900,600374,615982) PREDICTED: B (347 aa) initn: 2249 init1: 2249 opt: 2249 Z-score: 2008.6 bits: 380.7 E(85289): 3.8e-105 Smith-Waterman score: 2249; 99.7% identity (99.7% similar) in 347 aa overlap (173-519:1-347) 150 160 170 180 190 200 pF1KB5 VCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENT :::::::::::::::::::::::::::::: XP_016 MLGKIHLLEGDLDKAIEVYKKAVEFSPENT 10 20 30 210 220 230 240 250 260 pF1KB5 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 AFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRAYAEAVHLDKCNPLVNLNYAVLL ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_016 AFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE 280 290 300 310 320 330 510 pF1KB5 PAVESSPTETSEQIREK ::::::::::::::::: XP_016 PAVESSPTETSEQIREK 340 >>NP_001239607 (OMIM: 209900,600374,615982) Bardet-Biedl (347 aa) initn: 2249 init1: 2249 opt: 2249 Z-score: 2008.6 bits: 380.7 E(85289): 3.8e-105 Smith-Waterman score: 2249; 99.7% identity (99.7% similar) in 347 aa overlap (173-519:1-347) 150 160 170 180 190 200 pF1KB5 VCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENT :::::::::::::::::::::::::::::: NP_001 MLGKIHLLEGDLDKAIEVYKKAVEFSPENT 10 20 30 210 220 230 240 250 260 pF1KB5 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 AFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRAYAEAVHLDKCNPLVNLNYAVLL ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: NP_001 AFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE 280 290 300 310 320 330 510 pF1KB5 PAVESSPTETSEQIREK ::::::::::::::::: NP_001 PAVESSPTETSEQIREK 340 >>XP_011520151 (OMIM: 209900,600374,615982) PREDICTED: B (347 aa) initn: 2249 init1: 2249 opt: 2249 Z-score: 2008.6 bits: 380.7 E(85289): 3.8e-105 Smith-Waterman score: 2249; 99.7% identity (99.7% similar) in 347 aa overlap (173-519:1-347) 150 160 170 180 190 200 pF1KB5 VCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENT :::::::::::::::::::::::::::::: XP_011 MLGKIHLLEGDLDKAIEVYKKAVEFSPENT 10 20 30 210 220 230 240 250 260 pF1KB5 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 AFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRAYAEAVHLDKCNPLVNLNYAVLL ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_011 AFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE 280 290 300 310 320 330 510 pF1KB5 PAVESSPTETSEQIREK ::::::::::::::::: XP_011 PAVESSPTETSEQIREK 340 >>XP_016877941 (OMIM: 209900,600374,615982) PREDICTED: B (347 aa) initn: 2249 init1: 2249 opt: 2249 Z-score: 2008.6 bits: 380.7 E(85289): 3.8e-105 Smith-Waterman score: 2249; 99.7% identity (99.7% similar) in 347 aa overlap (173-519:1-347) 150 160 170 180 190 200 pF1KB5 VCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENT :::::::::::::::::::::::::::::: XP_016 MLGKIHLLEGDLDKAIEVYKKAVEFSPENT 10 20 30 210 220 230 240 250 260 pF1KB5 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 AFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRAYAEAVHLDKCNPLVNLNYAVLL ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_016 AFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE 280 290 300 310 320 330 510 pF1KB5 PAVESSPTETSEQIREK ::::::::::::::::: XP_016 PAVESSPTETSEQIREK 340 >>XP_016877942 (OMIM: 209900,600374,615982) PREDICTED: B (347 aa) initn: 2249 init1: 2249 opt: 2249 Z-score: 2008.6 bits: 380.7 E(85289): 3.8e-105 Smith-Waterman score: 2249; 99.7% identity (99.7% similar) in 347 aa overlap (173-519:1-347) 150 160 170 180 190 200 pF1KB5 VCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENT :::::::::::::::::::::::::::::: XP_016 MLGKIHLLEGDLDKAIEVYKKAVEFSPENT 10 20 30 210 220 230 240 250 260 pF1KB5 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVV 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYAS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 AFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRAYAEAVHLDKCNPLVNLNYAVLL ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_016 AFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPE 280 290 300 310 320 330 510 pF1KB5 PAVESSPTETSEQIREK ::::::::::::::::: XP_016 PAVESSPTETSEQIREK 340 >>NP_001307594 (OMIM: 209900,600374,615982) Bardet-Biedl (496 aa) initn: 1837 init1: 1837 opt: 1844 Z-score: 1647.0 bits: 314.3 E(85289): 5.3e-85 Smith-Waterman score: 3171; 95.4% identity (95.4% similar) in 519 aa overlap (1-519:1-496) 10 20 30 40 50 60 pF1KB5 MAEERVATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACKAVIKEQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEERVATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACKAVIKEQLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAIL :::::::::::::::::::::::::::::::::: ::: NP_001 EGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQ-----------------------AIL 190 200 210 250 260 270 280 290 300 pF1KB5 AAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLA 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 PFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRA ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_001 PFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRA 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 YAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEM 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 AQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRT 400 410 420 430 440 450 490 500 510 pF1KB5 LPSGAGGTSQFTKPPSLPLEPEPAVESSPTETSEQIREK ::::::::::::::::::::::::::::::::::::::: NP_001 LPSGAGGTSQFTKPPSLPLEPEPAVESSPTETSEQIREK 460 470 480 490 >>XP_016877939 (OMIM: 209900,600374,615982) PREDICTED: B (504 aa) initn: 1837 init1: 1837 opt: 1844 Z-score: 1646.9 bits: 314.3 E(85289): 5.4e-85 Smith-Waterman score: 3126; 94.9% identity (94.9% similar) in 514 aa overlap (6-519:14-504) 10 20 30 40 50 pF1KB5 MAEERVATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACK : :::::::::::::::::::::::::::::::::::::::::::: XP_016 MALTVVPSFSVSGVWKRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 AVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 LLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 MLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYD :::::::::::::::::::::::::::::::::::::::::: XP_016 MLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQ------------------ 190 200 210 220 240 250 260 270 280 290 pF1KB5 PTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISC ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -----AILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISC 230 240 250 260 270 300 310 320 330 340 350 pF1KB5 LKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLE 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB5 DTENAKRAYAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLE : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIENAKRAYAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLE 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB5 FDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAM 400 410 420 430 440 450 480 490 500 510 pF1KB5 SSAAAYRTLPSGAGGTSQFTKPPSLPLEPEPAVESSPTETSEQIREK ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSAAAYRTLPSGAGGTSQFTKPPSLPLEPEPAVESSPTETSEQIREK 460 470 480 490 500 519 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:38:14 2016 done: Sat Nov 5 18:38:15 2016 Total Scan time: 9.480 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]