Result of FASTA (omim) for
pF1KB5979
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5979, 520 aa
1>>>pF1KB5979 520 - 520 aa - 520 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7924+/-0.000324; mu= 13.2956+/- 0.021
mean_var=124.7384+/-25.704, 0's: 0 Z-trim(119.1): 84 B-trim: 1425 in 1/51
Lambda= 0.114835
statistics sampled from 32744 (32828) to 32744 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.385), width: 16
Scan time: 11.030
The best scores are: opt bits E(85289)
NP_001103348 (OMIM: 300307,302905,303400) T-box tr ( 520) 3528 595.5 1.3e-169
NP_058650 (OMIM: 300307,302905,303400) T-box trans ( 520) 3528 595.5 1.3e-169
XP_005262193 (OMIM: 300307,302905,303400) PREDICTE ( 521) 3516 593.5 5e-169
NP_001290404 (OMIM: 300307,302905,303400) T-box tr ( 400) 2753 467.0 4.6e-131
NP_001103349 (OMIM: 300307,302905,303400) T-box tr ( 400) 2753 467.0 4.6e-131
XP_011529274 (OMIM: 300307,302905,303400) PREDICTE ( 400) 2753 467.0 4.6e-131
XP_006724720 (OMIM: 300307,302905,303400) PREDICTE ( 350) 2103 359.3 1.1e-98
NP_001317606 (OMIM: 260660,604127) T-box transcrip ( 602) 1265 220.6 1e-56
NP_689593 (OMIM: 260660,604127) T-box transcriptio ( 496) 1241 216.6 1.4e-55
NP_001073977 (OMIM: 143100,143400,604613) T-box tr ( 607) 1210 211.5 5.7e-54
XP_011534550 (OMIM: 143100,143400,604613) PREDICTE ( 377) 1110 194.8 3.8e-49
XP_005271218 (OMIM: 260660,604127) PREDICTED: T-bo ( 635) 1104 194.0 1.1e-48
XP_016866961 (OMIM: 143100,143400,604613) PREDICTE ( 449) 1099 193.0 1.5e-48
XP_016866962 (OMIM: 143100,143400,604613) PREDICTE ( 376) 1096 192.5 1.9e-48
XP_011534551 (OMIM: 143100,143400,604613) PREDICTE ( 372) 1095 192.3 2.1e-48
XP_006715665 (OMIM: 143100,143400,604613) PREDICTE ( 364) 1093 192.0 2.6e-48
XP_011534549 (OMIM: 143100,143400,604613) PREDICTE ( 379) 1093 192.0 2.7e-48
NP_001071121 (OMIM: 606061,611363) T-box transcrip ( 447) 851 152.0 3.6e-36
NP_001159692 (OMIM: 606061,611363) T-box transcrip ( 297) 818 146.4 1.2e-34
NP_005983 (OMIM: 187500,188400,192430,217095,60205 ( 372) 760 136.8 1.1e-31
NP_005986 (OMIM: 604648) T-box transcription facto ( 385) 754 135.8 2.2e-31
XP_011543294 (OMIM: 604648) PREDICTED: T-box trans ( 430) 754 135.9 2.4e-31
NP_542377 (OMIM: 187500,188400,192430,217095,60205 ( 398) 745 134.4 6.3e-31
XP_016884417 (OMIM: 187500,188400,192430,217095,60 ( 448) 745 134.4 6.9e-31
XP_006724375 (OMIM: 187500,188400,192430,217095,60 ( 495) 737 133.1 1.9e-30
NP_542378 (OMIM: 187500,188400,192430,217095,60205 ( 495) 737 133.1 1.9e-30
XP_016884415 (OMIM: 187500,188400,192430,217095,60 ( 495) 737 133.1 1.9e-30
XP_016884414 (OMIM: 187500,188400,192430,217095,60 ( 545) 737 133.1 2e-30
XP_011523797 (OMIM: 147891,601719) PREDICTED: T-bo ( 417) 729 131.7 4.1e-30
XP_011523793 (OMIM: 147891,601719) PREDICTED: T-bo ( 608) 729 131.8 5.5e-30
XP_011523792 (OMIM: 147891,601719) PREDICTED: T-bo ( 609) 729 131.8 5.5e-30
NP_060958 (OMIM: 147891,601719) T-box transcriptio ( 545) 724 131.0 9e-30
NP_001308049 (OMIM: 147891,601719) T-box transcrip ( 546) 724 131.0 9e-30
XP_016875401 (OMIM: 142900,601620) PREDICTED: T-bo ( 534) 698 126.7 1.8e-28
NP_852259 (OMIM: 142900,601620) T-box transcriptio ( 518) 695 126.2 2.4e-28
NP_000183 (OMIM: 142900,601620) T-box transcriptio ( 518) 695 126.2 2.4e-28
NP_005987 (OMIM: 181450,601621) T-box transcriptio ( 723) 688 125.1 7e-28
NP_542448 (OMIM: 142900,601620) T-box transcriptio ( 468) 679 123.5 1.4e-27
XP_016877522 (OMIM: 616061) PREDICTED: MAX gene-as (1439) 630 115.7 9.4e-25
XP_011519703 (OMIM: 616061) PREDICTED: MAX gene-as (1549) 630 115.7 9.9e-25
XP_016877519 (OMIM: 616061) PREDICTED: MAX gene-as (2207) 630 115.8 1.3e-24
NP_001074010 (OMIM: 616061) MAX gene-associated pr (2856) 630 115.9 1.6e-24
XP_005254310 (OMIM: 616061) PREDICTED: MAX gene-as (2906) 630 115.9 1.6e-24
XP_005254309 (OMIM: 616061) PREDICTED: MAX gene-as (2956) 630 115.9 1.6e-24
XP_011519700 (OMIM: 616061) PREDICTED: MAX gene-as (3004) 630 115.9 1.7e-24
XP_011519699 (OMIM: 616061) PREDICTED: MAX gene-as (3005) 630 115.9 1.7e-24
NP_001157745 (OMIM: 616061) MAX gene-associated pr (3065) 630 116.0 1.7e-24
XP_005254306 (OMIM: 616061) PREDICTED: MAX gene-as (3066) 630 116.0 1.7e-24
XP_005254305 (OMIM: 616061) PREDICTED: MAX gene-as (3114) 630 116.0 1.7e-24
XP_005254301 (OMIM: 616061) PREDICTED: MAX gene-as (3115) 630 116.0 1.7e-24
>>NP_001103348 (OMIM: 300307,302905,303400) T-box transc (520 aa)
initn: 3528 init1: 3528 opt: 3528 Z-score: 3166.4 bits: 595.5 E(85289): 1.3e-169
Smith-Waterman score: 3528; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KB5 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS
430 440 450 460 470 480
490 500 510 520
pF1KB5 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
::::::::::::::::::::::::::::::::::::::::
NP_001 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
490 500 510 520
>>NP_058650 (OMIM: 300307,302905,303400) T-box transcrip (520 aa)
initn: 3528 init1: 3528 opt: 3528 Z-score: 3166.4 bits: 595.5 E(85289): 1.3e-169
Smith-Waterman score: 3528; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KB5 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS
430 440 450 460 470 480
490 500 510 520
pF1KB5 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
::::::::::::::::::::::::::::::::::::::::
NP_058 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
490 500 510 520
>>XP_005262193 (OMIM: 300307,302905,303400) PREDICTED: T (521 aa)
initn: 3204 init1: 3204 opt: 3516 Z-score: 3155.6 bits: 593.5 E(85289): 5e-169
Smith-Waterman score: 3516; 99.8% identity (99.8% similar) in 521 aa overlap (1-520:1-521)
10 20 30 40 50
pF1KB5 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPL-E
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_005 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLAE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 KQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 RMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 PDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 SLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 PEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 NSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNF
430 440 450 460 470 480
480 490 500 510 520
pF1KB5 SMPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
:::::::::::::::::::::::::::::::::::::::::
XP_005 SMPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
490 500 510 520
>>NP_001290404 (OMIM: 300307,302905,303400) T-box transc (400 aa)
initn: 2753 init1: 2753 opt: 2753 Z-score: 2474.0 bits: 467.0 E(85289): 4.6e-131
Smith-Waterman score: 2753; 100.0% identity (100.0% similar) in 400 aa overlap (121-520:1-400)
100 110 120 130 140 150
pF1KB5 DIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSK
::::::::::::::::::::::::::::::
NP_001 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSK
10 20 30
160 170 180 190 200 210
pF1KB5 RYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKG
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB5 HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKL
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB5 KIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGG
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 APSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPA
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 PERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSP
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB5 GNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHV
340 350 360 370 380 390
520
pF1KB5 HWYPAINHYL
::::::::::
NP_001 HWYPAINHYL
400
>>NP_001103349 (OMIM: 300307,302905,303400) T-box transc (400 aa)
initn: 2753 init1: 2753 opt: 2753 Z-score: 2474.0 bits: 467.0 E(85289): 4.6e-131
Smith-Waterman score: 2753; 100.0% identity (100.0% similar) in 400 aa overlap (121-520:1-400)
100 110 120 130 140 150
pF1KB5 DIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSK
::::::::::::::::::::::::::::::
NP_001 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSK
10 20 30
160 170 180 190 200 210
pF1KB5 RYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKG
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB5 HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKL
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB5 KIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGG
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 APSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPA
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 PERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSP
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB5 GNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHV
340 350 360 370 380 390
520
pF1KB5 HWYPAINHYL
::::::::::
NP_001 HWYPAINHYL
400
>>XP_011529274 (OMIM: 300307,302905,303400) PREDICTED: T (400 aa)
initn: 2753 init1: 2753 opt: 2753 Z-score: 2474.0 bits: 467.0 E(85289): 4.6e-131
Smith-Waterman score: 2753; 100.0% identity (100.0% similar) in 400 aa overlap (121-520:1-400)
100 110 120 130 140 150
pF1KB5 DIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSK
::::::::::::::::::::::::::::::
XP_011 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSK
10 20 30
160 170 180 190 200 210
pF1KB5 RYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKG
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB5 HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKL
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB5 KIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGG
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 APSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPA
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 PERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSP
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB5 GNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHV
340 350 360 370 380 390
520
pF1KB5 HWYPAINHYL
::::::::::
XP_011 HWYPAINHYL
400
>>XP_006724720 (OMIM: 300307,302905,303400) PREDICTED: T (350 aa)
initn: 1791 init1: 1791 opt: 2103 Z-score: 1892.9 bits: 359.3 E(85289): 1.1e-98
Smith-Waterman score: 2103; 99.7% identity (99.7% similar) in 317 aa overlap (1-316:1-317)
10 20 30 40 50
pF1KB5 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPL-E
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_006 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLAE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 KQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 RMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 PDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 SLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC
:::::::::::::::::
XP_006 WRPSFTLDFKTFGADTQILIEEGNKGKPSWIIRLGRNLKRFSSTHTLGME
310 320 330 340 350
>>NP_001317606 (OMIM: 260660,604127) T-box transcription (602 aa)
initn: 914 init1: 634 opt: 1265 Z-score: 1139.3 bits: 220.6 E(85289): 1e-56
Smith-Waterman score: 1400; 45.5% identity (69.0% similar) in 565 aa overlap (1-520:9-566)
10 20 30
pF1KB5 MALSSRARAFSVEALVGRPSKRKLQD--------PIQAEQP-------ELRE
.::::::.:::::::.: .::::.: ..: .: :
NP_001 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTEDAA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 KKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQ
.: : . . ..:... :: : .. . :: .. . :. . . :.:: ::.:::
NP_001 AHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEE--IQVELQ
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 GSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYH
..:::::::::::::::::::::::..:::. :::: .::..:.:.::::.::::::::
NP_001 CADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 SSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSM
::.::::::.: . :: :.:::: ::.:::::..:::..::::::.::.:::::.::
NP_001 SSKWMVAGNADSP-VPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSM
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 HKYKPRVHVIEQGSSVDLSQIQSLPT-EGVKTFSFKETEFTTVTAYQNQQITKLKIERNP
:::.::::::.. : ::: . .:. .:::::.: :: :::::::::::::.:::.:::
NP_001 HKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNP
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 FAKGFRDTGRNRGVLDGLLETYP-WRPSF-TLDFKTFGA--DTQSGSSGSSPVTSSGGAP
:::::::.:::: :....::: ::: :: :. : . :.::.:.::.::: :.:
NP_001 FAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTP
300 310 320 330 340 350
340 350 360 370 380
pF1KB5 SPLNS--LLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNL---PLCYKICPTNFWQQQPLV
:: : :::: : : ::: ..... : :. : :.:: : : . . . . :
NP_001 SPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLS
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB5 LPAPERLASSNSS--QSLAPLM-MEVP-MLSSLGVTNSKSGSS--EDSSDQYLQAPNSTN
. .:: :...: : .: ...: ..:.. . : :.: : . : . : :.
NP_001 DSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFP--TS
420 430 440 450 460 470
450 460 470 480 490
pF1KB5 QMLYGLQSPGNIFLPNSITPEAL-----------SCSFHPSYDFYRYNFSMPSRLISGSN
:. : .:. :: .: .:. . . :.: :..: ::: :: .. .
NP_001 QFQYVMQA-GNA-ASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPE
480 490 500 510 520 530
500 510 520
pF1KB5 HLKVNDDSQV--SFGEGKCNHVHWYPA-INHYL
.:...... . : ..: .. .. :. ..: .
NP_001 KLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGS
540 550 560 570 580 590
NP_001 SSQMSVHMV
600
>>NP_689593 (OMIM: 260660,604127) T-box transcription fa (496 aa)
initn: 789 init1: 634 opt: 1241 Z-score: 1118.9 bits: 216.6 E(85289): 1.4e-55
Smith-Waterman score: 1299; 48.6% identity (71.8% similar) in 465 aa overlap (86-520:3-460)
60 70 80 90 100 110
pF1KB5 EPLEKQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIIT
:.:: ::.::: ..:::::::::::::::
NP_689 MSSMEE--IQVELQCADLWKRFHDIGTEMIIT
10 20 30
120 130 140 150 160 170
pF1KB5 KAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPR
::::::::..:::. :::: .::..:.:.::::.::::::::::.::::::.: . ::
NP_689 KAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSP-VPPR
40 50 60 70 80
180 190 200 210 220 230
pF1KB5 FYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDL
:.:::: ::.:::::..:::..::::::.::.:::::.:::::.::::::.. : ::
NP_689 VYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDL
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB5 SQIQSLPT-EGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGL
: . .:. .:::::.: :: :::::::::::::.:::.::::::::::.:::: :...
NP_689 SPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAI
150 160 170 180 190 200
300 310 320 330 340
pF1KB5 LETYP-WRPSF-TLDFKTFGA--DTQSGSSGSSPVTSSGGAPSPLNS--LLSPLCFSPMF
.::: ::: :: :. : . :.::.:.::.::: :.::: : :::: : : :
NP_689 METYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTF
210 220 230 240 250 260
350 360 370 380 390 400
pF1KB5 HLPTSSLGMPCPEAYLPNVNL---PLCYKICPTNFWQQQPLVLPAPERLASSNSS--QSL
:: ..... : :. : :.:: : : . . . . : . .:: :...: :
NP_689 HLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPS
270 280 290 300 310 320
410 420 430 440 450
pF1KB5 APLM-MEVP-MLSSLGVTNSKSGSS--EDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSI
.: ...: ..:.. . : :.: : . : . : :.:. : .:. :: .:
NP_689 ETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFP--TSQFQYVMQA-GNA-ASSSS
330 340 350 360 370 380
460 470 480 490 500
pF1KB5 TPEAL-----------SCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQV--SFGEGK
.:. . . :.: :..: ::: :: .. ..:...... . : ..:
NP_689 SPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGA
390 400 410 420 430 440
510 520
pF1KB5 CNHVHWYPA-INHYL
.. .. :. ..: .
NP_689 FGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
450 460 470 480 490
>>NP_001073977 (OMIM: 143100,143400,604613) T-box transc (607 aa)
initn: 725 init1: 618 opt: 1210 Z-score: 1090.0 bits: 211.5 E(85289): 5.7e-54
Smith-Waterman score: 1231; 43.2% identity (64.4% similar) in 553 aa overlap (6-502:16-554)
10 20 30 40
pF1KB5 MALSSRARAFSVEALVGRPSKRKLQDP---IQAEQPELR------EKKGG
.:.:::::::.: ....:: . ::. . ::
NP_001 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGG
10 20 30 40 50 60
50 60 70 80
pF1KB5 EEEEERRSSAAGKSEPLEKQPKTEPSTS-------ASSGC--GSDSGY-----------G
:. . : . : . :. : :..:: : ..: :
NP_001 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
70 80 90 100 110 120
90 100 110 120 130
pF1KB5 NSSESLEEKDIQM--------ELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLD
. ..:: . . .:::.:::::::.::::::::::::::::..:::..:::
NP_001 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB5 PGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQI
: .::..:.:.::::.::::::::::.::::::.: . :: :.::::: ::::::::.
NP_001 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSP-VPPRVYIHPDSPASGETWMRQV
190 200 210 220 230
200 210 220 230 240 250
pF1KB5 ISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPT-EGVKTFSFK
::::..::::::.::.:::::.:::::.::::::.. . ::: :. .:. ::::.:::
NP_001 ISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFP
240 250 260 270 280 290
260 270 280 290 300 310
pF1KB5 ETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYP-WRPSF-TLDFKT
:: :::::::::::::.:::.::::::::::.:::: :..:.:.: ::::. :: :.
NP_001 ETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFED
300 310 320 330 340 350
320 330 340 350 360
pF1KB5 F-GADTQSGSSGSSPVTSSG-GAPSPLNSLLS-PLCFSPMFHL-PTSSLGMPCPEAYLPN
. : :...:.:. . ..: :.:. ::: : :: ::: :..: . : :
NP_001 IPGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTS--QLCSLA----
360 370 380 390 400 410
370 380 390 400 410 420
pF1KB5 VNLPLCYKICPTN--FWQQQPLVLPAPERLASSNSSQSLAPLMME--VPMLSSLGVTNSK
: :. : . .. : ........:: : . :: .:. :
NP_001 ---PADYSACARSGLTLNRYSTSLAETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSM
420 430 440 450 460 470
430 440 450 460 470
pF1KB5 SGSSEDS-----SDQYLQAPNSTNQMLYGLQSPG-NIFLPNSITPEALSCSF--HPSYDF
.:.. :. .. .: . . :. : . ::. : : :. : .. .: : .
NP_001 GGTDGDTFSCPQTSLSMQISGMSPQLQYIMPSPSSNAFATNQ-THQGSYNTFRLHSPCAL
480 490 500 510 520
480 490 500 510 520
pF1KB5 YRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
: :::: .: .. ... .:: ::
NP_001 YGYNFSTSPKLAASPEKIV---SSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSF
530 540 550 560 570 580
520 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:10:45 2016 done: Sat Nov 5 18:10:47 2016
Total Scan time: 11.030 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]