FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5982, 568 aa 1>>>pF1KB5982 568 - 568 aa - 568 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7071+/-0.000439; mu= 16.6954+/- 0.027 mean_var=83.5379+/-18.115, 0's: 0 Z-trim(109.7): 418 B-trim: 0 in 0/51 Lambda= 0.140324 statistics sampled from 17412 (17868) to 17412 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.561), E-opt: 0.2 (0.209), width: 16 Scan time: 9.590 The best scores are: opt bits E(85289) NP_067646 (OMIM: 614522) kelch-like protein 12 iso ( 568) 3809 781.8 0 NP_001289980 (OMIM: 614522) kelch-like protein 12 ( 606) 3809 781.8 0 XP_011508137 (OMIM: 614522) PREDICTED: kelch-like ( 623) 3809 781.8 0 XP_016857484 (OMIM: 614522) PREDICTED: kelch-like ( 471) 3113 640.8 2.8e-183 XP_011508138 (OMIM: 614522) PREDICTED: kelch-like ( 526) 3113 640.9 3.1e-183 NP_001290038 (OMIM: 614522) kelch-like protein 12 ( 467) 2284 473.0 9.2e-133 XP_011508139 (OMIM: 614522) PREDICTED: kelch-like ( 522) 2284 473.0 1e-132 NP_059111 (OMIM: 605775,614495) kelch-like protein ( 587) 1505 315.4 3.3e-85 NP_001244123 (OMIM: 605775,614495) kelch-like prot ( 555) 1499 314.1 7.3e-85 NP_009177 (OMIM: 605774) kelch-like protein 2 isof ( 593) 1490 312.3 2.7e-84 NP_001154993 (OMIM: 605774) kelch-like protein 2 i ( 597) 1490 312.3 2.7e-84 XP_016863163 (OMIM: 605774) PREDICTED: kelch-like ( 555) 1481 310.5 9.2e-84 XP_011529874 (OMIM: 605774) PREDICTED: kelch-like ( 633) 1452 304.7 6e-82 NP_001165125 (OMIM: 608064) kelch-like protein 5 i ( 568) 1431 300.4 1e-80 NP_001007076 (OMIM: 608064) kelch-like protein 5 i ( 709) 1431 300.4 1.2e-80 NP_057074 (OMIM: 608064) kelch-like protein 5 isof ( 755) 1431 300.5 1.3e-80 XP_016863764 (OMIM: 608064) PREDICTED: kelch-like ( 788) 1431 300.5 1.4e-80 XP_005262712 (OMIM: 608064) PREDICTED: kelch-like ( 789) 1431 300.5 1.4e-80 XP_016863763 (OMIM: 608064) PREDICTED: kelch-like ( 804) 1411 296.4 2.3e-79 XP_016863762 (OMIM: 608064) PREDICTED: kelch-like ( 804) 1411 296.4 2.3e-79 XP_011512001 (OMIM: 608064) PREDICTED: kelch-like ( 804) 1411 296.4 2.3e-79 XP_011512003 (OMIM: 608064) PREDICTED: kelch-like ( 788) 1408 295.8 3.4e-79 XP_011512002 (OMIM: 608064) PREDICTED: kelch-like ( 788) 1408 295.8 3.4e-79 XP_016863765 (OMIM: 608064) PREDICTED: kelch-like ( 788) 1408 295.8 3.4e-79 XP_016876167 (OMIM: 605332) PREDICTED: kelch-like ( 575) 1406 295.3 3.5e-79 NP_065917 (OMIM: 605332) kelch-like protein 1 isof ( 748) 1406 295.4 4.3e-79 NP_001278932 (OMIM: 611967) kelch-like protein 8 i ( 620) 1400 294.1 8.6e-79 NP_065854 (OMIM: 611967) kelch-like protein 8 isof ( 620) 1400 294.1 8.6e-79 NP_061990 (OMIM: 300348) kelch-like protein 4 isof ( 718) 1367 287.5 1e-76 NP_950240 (OMIM: 608064) kelch-like protein 5 isof ( 694) 1359 285.9 3e-76 NP_476503 (OMIM: 300348) kelch-like protein 4 isof ( 720) 1350 284.0 1.1e-75 NP_001273654 (OMIM: 605332) kelch-like protein 1 i ( 687) 1328 279.6 2.3e-74 NP_001244124 (OMIM: 605775,614495) kelch-like prot ( 505) 1323 278.5 3.6e-74 XP_016876168 (OMIM: 605332) PREDICTED: kelch-like ( 525) 1319 277.7 6.5e-74 NP_001154994 (OMIM: 605774) kelch-like protein 2 i ( 505) 1299 273.6 1e-72 XP_016863165 (OMIM: 605774) PREDICTED: kelch-like ( 505) 1299 273.6 1e-72 NP_036421 (OMIM: 606016) kelch-like ECH-associated ( 624) 1247 263.2 1.8e-69 XP_005260230 (OMIM: 606016) PREDICTED: kelch-like ( 624) 1247 263.2 1.8e-69 XP_011526754 (OMIM: 606016) PREDICTED: kelch-like ( 624) 1247 263.2 1.8e-69 NP_987096 (OMIM: 606016) kelch-like ECH-associated ( 624) 1247 263.2 1.8e-69 XP_005260231 (OMIM: 606016) PREDICTED: kelch-like ( 624) 1247 263.2 1.8e-69 NP_001317953 (OMIM: 605774) kelch-like protein 2 i ( 496) 1227 259.0 2.5e-68 XP_011529878 (OMIM: 605774) PREDICTED: kelch-like ( 496) 1227 259.0 2.5e-68 NP_001316524 (OMIM: 608778,615081) kelch-like prot ( 608) 1219 257.5 9.1e-68 NP_689680 (OMIM: 608778,615081) kelch-like protein ( 608) 1219 257.5 9.1e-68 NP_001278935 (OMIM: 611967) kelch-like protein 8 i ( 544) 1165 246.5 1.6e-64 XP_016863164 (OMIM: 605774) PREDICTED: kelch-like ( 415) 1099 233.1 1.4e-60 NP_001316525 (OMIM: 608778,615081) kelch-like prot ( 520) 1071 227.5 8.4e-59 NP_001026880 (OMIM: 611119,612943,617055) kelch-li ( 586) 1030 219.2 2.9e-56 XP_016867928 (OMIM: 611119,612943,617055) PREDICTE ( 564) 1016 216.4 2e-55 >>NP_067646 (OMIM: 614522) kelch-like protein 12 isoform (568 aa) initn: 3809 init1: 3809 opt: 3809 Z-score: 4171.8 bits: 781.8 E(85289): 0 Smith-Waterman score: 3809; 100.0% identity (100.0% similar) in 568 aa overlap (1-568:1-568) 10 20 30 40 50 60 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY 490 500 510 520 530 540 550 560 pF1KB5 DPIIDSWEVVTSMGTQRCDAGVCVLREK :::::::::::::::::::::::::::: NP_067 DPIIDSWEVVTSMGTQRCDAGVCVLREK 550 560 >>NP_001289980 (OMIM: 614522) kelch-like protein 12 isof (606 aa) initn: 3809 init1: 3809 opt: 3809 Z-score: 4171.4 bits: 781.8 E(85289): 0 Smith-Waterman score: 3809; 100.0% identity (100.0% similar) in 568 aa overlap (1-568:39-606) 10 20 30 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSN :::::::::::::::::::::::::::::: NP_001 SVGFLDVKKFLSTWKLQNPRTHFVLSPHCFMGGIMAPKDIMTNTHAKSILNSMNSLRKSN 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB5 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB5 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB5 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB5 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB5 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR 490 500 510 520 530 540 520 530 540 550 560 pF1KB5 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK 550 560 570 580 590 600 >>XP_011508137 (OMIM: 614522) PREDICTED: kelch-like prot (623 aa) initn: 3809 init1: 3809 opt: 3809 Z-score: 4171.2 bits: 781.8 E(85289): 0 Smith-Waterman score: 3809; 100.0% identity (100.0% similar) in 568 aa overlap (1-568:56-623) 10 20 30 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSN :::::::::::::::::::::::::::::: XP_011 GFAVIPRRVWNSGAQLQNPRTHFVLSPHCFMGGIMAPKDIMTNTHAKSILNSMNSLRKSN 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB5 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB5 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB5 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB5 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB5 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB5 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS 390 400 410 420 430 440 400 410 420 430 440 450 pF1KB5 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB5 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR 510 520 530 540 550 560 520 530 540 550 560 pF1KB5 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK 570 580 590 600 610 620 >>XP_016857484 (OMIM: 614522) PREDICTED: kelch-like prot (471 aa) initn: 3390 init1: 3113 opt: 3113 Z-score: 3411.4 bits: 640.8 E(85289): 2.8e-183 Smith-Waterman score: 3113; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464) 10 20 30 40 50 60 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG :::::::::::::::::::::::::::::::::::::::::::: XP_016 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSDMMVIPC 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY >>XP_011508138 (OMIM: 614522) PREDICTED: kelch-like prot (526 aa) initn: 3390 init1: 3113 opt: 3113 Z-score: 3410.7 bits: 640.9 E(85289): 3.1e-183 Smith-Waterman score: 3113; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:56-519) 10 20 30 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSN :::::::::::::::::::::::::::::: XP_011 GFAVIPRRVWNSGAQLQNPRTHFVLSPHCFMGGIMAPKDIMTNTHAKSILNSMNSLRKSN 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB5 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB5 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB5 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB5 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB5 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB5 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS 390 400 410 420 430 440 400 410 420 430 440 450 pF1KB5 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB5 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR :::::::::::::: XP_011 GHWTNVTPMATKRSDMMVIPC 510 520 >>NP_001290038 (OMIM: 614522) kelch-like protein 12 isof (467 aa) initn: 3123 init1: 1844 opt: 2284 Z-score: 2504.5 bits: 473.0 E(85289): 9.2e-133 Smith-Waterman score: 2925; 82.2% identity (82.2% similar) in 568 aa overlap (1-568:1-467) 10 20 30 40 50 60 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE ::::::::::::::::::::::::::::::::::::: NP_001 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARL----------------------- 250 260 270 310 320 330 340 350 360 pF1KB5 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY NP_001 ------------------------------------------------------------ 370 380 390 400 410 420 pF1KB5 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG :::::::::::::::::::::::::::::::::::::::::: NP_001 ------------------DMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG 280 290 300 310 430 440 450 460 470 480 pF1KB5 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG 320 330 340 350 360 370 490 500 510 520 530 540 pF1KB5 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY 380 390 400 410 420 430 550 560 pF1KB5 DPIIDSWEVVTSMGTQRCDAGVCVLREK :::::::::::::::::::::::::::: NP_001 DPIIDSWEVVTSMGTQRCDAGVCVLREK 440 450 460 >>XP_011508139 (OMIM: 614522) PREDICTED: kelch-like prot (522 aa) initn: 3123 init1: 1844 opt: 2284 Z-score: 2503.8 bits: 473.0 E(85289): 1e-132 Smith-Waterman score: 2925; 82.2% identity (82.2% similar) in 568 aa overlap (1-568:56-522) 10 20 30 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSN :::::::::::::::::::::::::::::: XP_011 GFAVIPRRVWNSGAQLQNPRTHFVLSPHCFMGGIMAPKDIMTNTHAKSILNSMNSLRKSN 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB5 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB5 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB5 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB5 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB5 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR ::::::: XP_011 PRTRARL----------------------------------------------------- 330 340 350 360 370 380 390 pF1KB5 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS :::::::::::: XP_011 ------------------------------------------------DMIYVSGGFDGS 340 400 410 420 430 440 450 pF1KB5 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT 350 360 370 380 390 400 460 470 480 490 500 510 pF1KB5 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR 410 420 430 440 450 460 520 530 540 550 560 pF1KB5 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK 470 480 490 500 510 520 >>NP_059111 (OMIM: 605775,614495) kelch-like protein 3 i (587 aa) initn: 1276 init1: 899 opt: 1505 Z-score: 1650.7 bits: 315.4 E(85289): 3.3e-85 Smith-Waterman score: 1505; 41.1% identity (72.8% similar) in 569 aa overlap (8-567:24-585) 10 20 30 40 pF1KB5 MGGIMAPKDIMTN-THAKSILNSMNSLRKSNTLCDVTLRVEQKD . : .: .: . .. :: ::... :::: . .:. . NP_059 MEGESVKLSSQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 FPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENV . :::.:::::: :::::::...::. ..:. . ..:. :.:..:: ..:: ::: NP_059 IEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENV 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB5 QELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP : ::::: :::: :.: ::.::.::: :.:::::: ::..:.:.::.: :......::: NP_059 QVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFP 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 EVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVR ::. :::. :: .: .::. :.. :.::: ::::::.:... :. : : . .:...:: NP_059 EVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB5 MPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRP-ELRSQMQGPRTRARLGAN-- .::: :...... : .:. . :.:.. :: :.:: : . : ...:::. : .. NP_059 LPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLP 250 260 270 280 290 300 290 300 310 320 330 pF1KB5 EVLLVVGGFGSQQSP--IDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYD .:..:::: :.: : :: :: . ..:. . . .: .. : . ..:..::.. NP_059 KVMIVVGG----QAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFN 310 320 330 340 350 340 350 360 370 380 390 pF1KB5 GRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMER : :. .:. : . :. : :.: :. ::. ::..:.:..:. :::::: .:.: NP_059 GSLRVRTVDVYDGVKDQ---WTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEA 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB5 YDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLN--ILNSVEKYDPHTGHWTNV :. . ..: ... :.: : ..:. :. : .: .::::: . :..::.:.: :..: : NP_059 YSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYV 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB5 TPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGAT . :.:.::::::..:. ..:..:: :: .:::.:. :..: :..:. : .:. NP_059 ADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVC 480 490 500 510 520 530 520 530 540 550 560 pF1KB5 VLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVV-TSMGTQRCDAGVCVLREK .. : ::...: ::. :.:.: :.:. :.: .. :.:.: : ::: :... NP_059 AVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL 540 550 560 570 580 >>NP_001244123 (OMIM: 605775,614495) kelch-like protein (555 aa) initn: 1276 init1: 899 opt: 1499 Z-score: 1644.5 bits: 314.1 E(85289): 7.3e-85 Smith-Waterman score: 1499; 41.8% identity (73.2% similar) in 553 aa overlap (23-567:8-553) 10 20 30 40 50 60 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA :: ::... :::: . .:. .. :::.:::::: :::: NP_001 MGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCA 10 20 30 40 70 80 90 100 110 120 pF1KB5 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ :::...::. ..:. . ..:. :.:..:: ..:: :::: ::::: :::: :.: NP_001 MFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE ::.::.::: :.:::::: ::..:.:.::.: :......:::::. :::. :: .: NP_001 NCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVC 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP .::. :.. :.::: ::::::.:... :. : : . .:...::.::: :...... : NP_001 SLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEA 170 180 190 200 210 220 250 260 270 280 290 pF1KB5 FIRCSLQCRDLVDEAKKFHLRP-ELRSQMQGPRTRARLGAN--EVLLVVGGFGSQQSP-- .:. . :.:.. :: :.:: : . : ...:::. : .. .:..:::: :.: NP_001 LIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGG----QAPKA 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 IDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADE : :: :: . ..:. . . .: .. : . ..:..::..: :. .:. : . :. NP_001 IRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQ 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 DGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTA : :.: :. ::. ::..:.:..:. :::::: .:.: :. . ..: ... :.: NP_001 ---WTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTR 350 360 370 380 390 420 430 440 450 460 470 pF1KB5 REGAGLVVASGVIYCLGGYDGLN--ILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLND : ..:. :. : .: .::::: . :..::.:.: :..: :. :.:.::::::..:. NP_001 RSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSG 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB5 HIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSL ..:..:: :: .:::.:. :..: :..:. : .:. .. : ::...: ::. NP_001 QLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCN 460 470 480 490 500 510 540 550 560 pF1KB5 LSSIECYDPIIDSWEVV-TSMGTQRCDAGVCVLREK :.:.: :.:. :.: .. :.:.: : ::: :... NP_001 LASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL 520 530 540 550 >>NP_009177 (OMIM: 605774) kelch-like protein 2 isoform (593 aa) initn: 1319 init1: 938 opt: 1490 Z-score: 1634.3 bits: 312.3 E(85289): 2.7e-84 Smith-Waterman score: 1490; 43.3% identity (70.8% similar) in 559 aa overlap (15-565:38-589) 10 20 30 40 pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDF : :. .. :: ::..: :::::. .:. .. NP_009 PACTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 PAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQ :::.:::::: :: ::::.:.::. : :. . . :...:.:.::: ..:: :::: NP_009 SAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQ 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB5 ELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPE ::::: ::::. ::..::::::::: : :::::: ::. : :.::.. :......:: . NP_009 VLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFAD 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 VVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRM :: :::. :. .: .::. :.. ..::: :::::: ::.: : :.: . :...::. NP_009 VVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB5 PLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRP-ELRSQMQGPRTRARLGAN--E ::: .:... .. : ... : :.: . :: :.:: : : : :.. ::: : : . NP_009 PLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRILMKSVRTRLRTPMNLPK 250 260 270 280 290 300 290 300 310 320 330 pF1KB5 VLLVVGGFGSQQSP--IDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDG ...:::: :.: : :: :: : ..: . . .: .. : . ....::..: NP_009 LMVVVGG----QAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNG 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB5 RSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERY :. .:. : . :. : ::: : ::. ::..:. ..:. :::::: .:.: : NP_009 SLRVRTVDSYDPVKDQ---WTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAY 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB5 DPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLN--ILNSVEKYDPHTGHWTNVT . . ..: .. :.: : ..:. :..:..: .::::: . :..:: :. :..:: .. NP_009 NIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATTNEWTYIA 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB5 PMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATV :.:.::::::..::. .:.::: :: .:::.:. :..: :..:. : .:. . NP_009 EMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCA 490 500 510 520 530 540 520 530 540 550 560 pF1KB5 LRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTS-MGTQRCDAGVCVLREK . : ::...: ::. :.:.: :.: :.: ::.: :.: : ::: :. NP_009 VNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL 550 560 570 580 590 568 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:51:21 2016 done: Sat Nov 5 10:51:23 2016 Total Scan time: 9.590 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]