FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6010, 1231 aa 1>>>pF1KB6010 1231 - 1231 aa - 1231 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5305+/-0.000454; mu= 23.1491+/- 0.028 mean_var=98.6109+/-19.890, 0's: 0 Z-trim(111.4): 34 B-trim: 565 in 1/52 Lambda= 0.129155 statistics sampled from 20014 (20048) to 20014 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.235), width: 16 Scan time: 15.560 The best scores are: opt bits E(85289) XP_005262418 (OMIM: 300826) PREDICTED: cohesin sub (1231) 8096 1520.3 0 XP_016884723 (OMIM: 300826) PREDICTED: cohesin sub (1231) 8096 1520.3 0 XP_016884722 (OMIM: 300826) PREDICTED: cohesin sub (1231) 8096 1520.3 0 XP_016884721 (OMIM: 300826) PREDICTED: cohesin sub (1231) 8096 1520.3 0 NP_006594 (OMIM: 300826) cohesin subunit SA-2 isof (1231) 8096 1520.3 0 NP_001269347 (OMIM: 300826) cohesin subunit SA-2 i (1231) 8096 1520.3 0 NP_001036216 (OMIM: 300826) cohesin subunit SA-2 i (1231) 8096 1520.3 0 XP_005262415 (OMIM: 300826) PREDICTED: cohesin sub (1268) 7601 1428.1 0 NP_001036215 (OMIM: 300826) cohesin subunit SA-2 i (1268) 7601 1428.1 0 XP_011529555 (OMIM: 300826) PREDICTED: cohesin sub (1268) 7601 1428.1 0 XP_005262416 (OMIM: 300826) PREDICTED: cohesin sub (1268) 7601 1428.1 0 NP_001036214 (OMIM: 300826) cohesin subunit SA-2 i (1268) 7601 1428.1 0 XP_005262417 (OMIM: 300826) PREDICTED: cohesin sub (1268) 7601 1428.1 0 XP_006724790 (OMIM: 300826) PREDICTED: cohesin sub (1268) 7601 1428.1 0 XP_005262414 (OMIM: 300826) PREDICTED: cohesin sub (1268) 7601 1428.1 0 XP_016884724 (OMIM: 300826) PREDICTED: cohesin sub (1199) 7121 1338.7 0 XP_006724791 (OMIM: 300826) PREDICTED: cohesin sub (1199) 7121 1338.7 0 NP_005853 (OMIM: 604358) cohesin subunit SA-1 [Hom (1258) 5509 1038.3 0 XP_016861012 (OMIM: 604358) PREDICTED: cohesin sub (1121) 5087 959.6 0 XP_011510633 (OMIM: 604358) PREDICTED: cohesin sub (1121) 5087 959.6 0 XP_011510631 (OMIM: 604358) PREDICTED: cohesin sub (1121) 5087 959.6 0 XP_016861013 (OMIM: 604358) PREDICTED: cohesin sub (1032) 4519 853.8 0 NP_001269646 (OMIM: 608489,615723) cohesin subunit (1226) 3714 703.8 1.7e-201 XP_011514044 (OMIM: 608489,615723) PREDICTED: cohe (1226) 3714 703.8 1.7e-201 XP_016867172 (OMIM: 608489,615723) PREDICTED: cohe (1239) 3714 703.8 1.7e-201 XP_016867174 (OMIM: 608489,615723) PREDICTED: cohe (1239) 3714 703.8 1.7e-201 XP_016867173 (OMIM: 608489,615723) PREDICTED: cohe (1239) 3714 703.8 1.7e-201 NP_001269645 (OMIM: 608489,615723) cohesin subunit (1225) 3713 703.7 1.9e-201 NP_036579 (OMIM: 608489,615723) cohesin subunit SA (1225) 3713 703.7 1.9e-201 XP_016867175 (OMIM: 608489,615723) PREDICTED: cohe (1238) 3713 703.7 2e-201 NP_001269647 (OMIM: 608489,615723) cohesin subunit (1167) 3390 643.4 2.5e-183 XP_016867176 (OMIM: 608489,615723) PREDICTED: cohe (1180) 3390 643.5 2.5e-183 XP_016861014 (OMIM: 604358) PREDICTED: cohesin sub ( 821) 3281 623.0 2.5e-177 XP_016867686 (OMIM: 612550) PREDICTED: tripartite ( 185) 475 99.5 2.1e-20 >>XP_005262418 (OMIM: 300826) PREDICTED: cohesin subunit (1231 aa) initn: 8096 init1: 8096 opt: 8096 Z-score: 8151.2 bits: 1520.3 E(85289): 0 Smith-Waterman score: 8096; 100.0% identity (100.0% similar) in 1231 aa overlap (1-1231:1-1231) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB6 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KB6 SKNRRERTELKPDFFDPASIMDESVLGVSMF ::::::::::::::::::::::::::::::: XP_005 SKNRRERTELKPDFFDPASIMDESVLGVSMF 1210 1220 1230 >>XP_016884723 (OMIM: 300826) PREDICTED: cohesin subunit (1231 aa) initn: 8096 init1: 8096 opt: 8096 Z-score: 8151.2 bits: 1520.3 E(85289): 0 Smith-Waterman score: 8096; 100.0% identity (100.0% similar) in 1231 aa overlap (1-1231:1-1231) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB6 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KB6 SKNRRERTELKPDFFDPASIMDESVLGVSMF ::::::::::::::::::::::::::::::: XP_016 SKNRRERTELKPDFFDPASIMDESVLGVSMF 1210 1220 1230 >>XP_016884722 (OMIM: 300826) PREDICTED: cohesin subunit (1231 aa) initn: 8096 init1: 8096 opt: 8096 Z-score: 8151.2 bits: 1520.3 E(85289): 0 Smith-Waterman score: 8096; 100.0% identity (100.0% similar) in 1231 aa overlap (1-1231:1-1231) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB6 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KB6 SKNRRERTELKPDFFDPASIMDESVLGVSMF ::::::::::::::::::::::::::::::: XP_016 SKNRRERTELKPDFFDPASIMDESVLGVSMF 1210 1220 1230 >>XP_016884721 (OMIM: 300826) PREDICTED: cohesin subunit (1231 aa) initn: 8096 init1: 8096 opt: 8096 Z-score: 8151.2 bits: 1520.3 E(85289): 0 Smith-Waterman score: 8096; 100.0% identity (100.0% similar) in 1231 aa overlap (1-1231:1-1231) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB6 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KB6 SKNRRERTELKPDFFDPASIMDESVLGVSMF ::::::::::::::::::::::::::::::: XP_016 SKNRRERTELKPDFFDPASIMDESVLGVSMF 1210 1220 1230 >>NP_006594 (OMIM: 300826) cohesin subunit SA-2 isoform (1231 aa) initn: 8096 init1: 8096 opt: 8096 Z-score: 8151.2 bits: 1520.3 E(85289): 0 Smith-Waterman score: 8096; 100.0% identity (100.0% similar) in 1231 aa overlap (1-1231:1-1231) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB6 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KB6 SKNRRERTELKPDFFDPASIMDESVLGVSMF ::::::::::::::::::::::::::::::: NP_006 SKNRRERTELKPDFFDPASIMDESVLGVSMF 1210 1220 1230 >>NP_001269347 (OMIM: 300826) cohesin subunit SA-2 isofo (1231 aa) initn: 8096 init1: 8096 opt: 8096 Z-score: 8151.2 bits: 1520.3 E(85289): 0 Smith-Waterman score: 8096; 100.0% identity (100.0% similar) in 1231 aa overlap (1-1231:1-1231) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB6 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KB6 SKNRRERTELKPDFFDPASIMDESVLGVSMF ::::::::::::::::::::::::::::::: NP_001 SKNRRERTELKPDFFDPASIMDESVLGVSMF 1210 1220 1230 >>NP_001036216 (OMIM: 300826) cohesin subunit SA-2 isofo (1231 aa) initn: 8096 init1: 8096 opt: 8096 Z-score: 8151.2 bits: 1520.3 E(85289): 0 Smith-Waterman score: 8096; 100.0% identity (100.0% similar) in 1231 aa overlap (1-1231:1-1231) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB6 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KB6 SKNRRERTELKPDFFDPASIMDESVLGVSMF ::::::::::::::::::::::::::::::: NP_001 SKNRRERTELKPDFFDPASIMDESVLGVSMF 1210 1220 1230 >>XP_005262415 (OMIM: 300826) PREDICTED: cohesin subunit (1268 aa) initn: 8126 init1: 7601 opt: 7601 Z-score: 7652.5 bits: 1428.1 E(85289): 0 Smith-Waterman score: 7979; 97.1% identity (97.1% similar) in 1263 aa overlap (1-1226:1-1263) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 pF1KB6 VYPMQTEHHQTPLDYN-------------------------------------RRGTSLM :::::::::::::::: ::::::: XP_005 VYPMQTEHHQTPLDYNTQVTWMLAQRQQEEARQQQERAAMSYVKLRTNLQHAIRRGTSLM 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KB6 EDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDE 1210 1220 1230 1240 1250 1260 1230 pF1KB6 SVLGVSMF ::: XP_005 SVLGVSMF >>NP_001036215 (OMIM: 300826) cohesin subunit SA-2 isofo (1268 aa) initn: 8126 init1: 7601 opt: 7601 Z-score: 7652.5 bits: 1428.1 E(85289): 0 Smith-Waterman score: 7979; 97.1% identity (97.1% similar) in 1263 aa overlap (1-1226:1-1263) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 pF1KB6 VYPMQTEHHQTPLDYN-------------------------------------RRGTSLM :::::::::::::::: ::::::: NP_001 VYPMQTEHHQTPLDYNTQVTWMLAQRQQEEARQQQERAAMSYVKLRTNLQHAIRRGTSLM 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KB6 EDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDE 1210 1220 1230 1240 1250 1260 1230 pF1KB6 SVLGVSMF ::: NP_001 SVLGVSMF >>XP_011529555 (OMIM: 300826) PREDICTED: cohesin subunit (1268 aa) initn: 8126 init1: 7601 opt: 7601 Z-score: 7652.5 bits: 1428.1 E(85289): 0 Smith-Waterman score: 7979; 97.1% identity (97.1% similar) in 1263 aa overlap (1-1226:1-1263) 10 20 30 40 50 60 pF1KB6 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB6 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB6 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB6 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB6 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB6 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS 1090 1100 1110 1120 1130 1140 1150 1160 pF1KB6 VYPMQTEHHQTPLDYN-------------------------------------RRGTSLM :::::::::::::::: ::::::: XP_011 VYPMQTEHHQTPLDYNTQVTWMLAQRQQEEARQQQERAAMSYVKLRTNLQHAIRRGTSLM 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KB6 EDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDE 1210 1220 1230 1240 1250 1260 1230 pF1KB6 SVLGVSMF ::: XP_011 SVLGVSMF 1231 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:51:46 2016 done: Sat Nov 5 20:51:48 2016 Total Scan time: 15.560 Total Display time: 0.620 Function used was FASTA [36.3.4 Apr, 2011]