FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6013, 576 aa 1>>>pF1KB6013 576 - 576 aa - 576 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1785+/-0.000965; mu= 16.6472+/- 0.058 mean_var=174.0559+/-33.947, 0's: 0 Z-trim(111.9): 91 B-trim: 3 in 1/52 Lambda= 0.097214 statistics sampled from 12672 (12775) to 12672 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.392), width: 16 Scan time: 2.990 The best scores are: opt bits E(32554) CCDS11575.1 WFIKKN2 gene_id:124857|Hs108|chr17 ( 576) 4123 590.9 1.4e-168 CCDS82159.1 WFIKKN2 gene_id:124857|Hs108|chr17 ( 483) 3427 493.2 3e-139 CCDS10414.1 WFIKKN1 gene_id:117166|Hs108|chr16 ( 548) 1582 234.5 2.6e-61 >>CCDS11575.1 WFIKKN2 gene_id:124857|Hs108|chr17 (576 aa) initn: 4123 init1: 4123 opt: 4123 Z-score: 3140.0 bits: 590.9 E(32554): 1.4e-168 Smith-Waterman score: 4123; 100.0% identity (100.0% similar) in 576 aa overlap (1-576:1-576) 10 20 30 40 50 60 pF1KB6 MWAPRCRRFWSRWEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MWAPRCRRFWSRWEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 WPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 CHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 GNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 ALVTVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ALVTVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAML 490 500 510 520 530 540 550 560 570 pF1KB6 RPDSFVGASSARRVRKLREVMHKKTCDVLKEFLGLH :::::::::::::::::::::::::::::::::::: CCDS11 RPDSFVGASSARRVRKLREVMHKKTCDVLKEFLGLH 550 560 570 >>CCDS82159.1 WFIKKN2 gene_id:124857|Hs108|chr17 (483 aa) initn: 3427 init1: 3427 opt: 3427 Z-score: 2613.3 bits: 493.2 E(32554): 3e-139 Smith-Waterman score: 3427; 100.0% identity (100.0% similar) in 483 aa overlap (94-576:1-483) 70 80 90 100 110 120 pF1KB6 RECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSEC :::::::::::::::::::::::::::::: CCDS82 MDVKGKKGPVGMPKEATCDHFMCLQQGSEC 10 20 30 130 140 150 160 170 180 pF1KB6 DIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 DIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPN 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB6 TSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITW 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB6 EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLS 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 VVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHR 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB6 NLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 NLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNG 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB6 NNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGRALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 NNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGRALV 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB6 TVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAMLRPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAMLRPD 400 410 420 430 440 450 550 560 570 pF1KB6 SFVGASSARRVRKLREVMHKKTCDVLKEFLGLH ::::::::::::::::::::::::::::::::: CCDS82 SFVGASSARRVRKLREVMHKKTCDVLKEFLGLH 460 470 480 >>CCDS10414.1 WFIKKN1 gene_id:117166|Hs108|chr16 (548 aa) initn: 1756 init1: 535 opt: 1582 Z-score: 1214.3 bits: 234.5 E(32554): 2.6e-61 Smith-Waterman score: 2193; 56.1% identity (77.0% similar) in 560 aa overlap (19-572:7-546) 10 20 30 40 50 60 pF1KB6 MWAPRCRRFWSRWEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQS :: ::::: . . :: . :: :.:::...::::::::: CCDS10 MPALRPLLPLLLLLRLTSGAGLLPGLG-SHPGVCPNQLSPNLWVDAQS 10 20 30 40 70 80 90 100 110 120 pF1KB6 TCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQG ::.::: ::.: . :::: :::: .::::::. : .:.. :.:. :.: ::: CCDS10 TCERECSRDQDCAAAEKCCINVCGLHSCVAARF---PG--SPAAPTTAASCEGFVCPQQG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 SECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFT :.::::::::::.:.::::::::::::::::::::::::::::: .:. : .: :.. .. CCDS10 SDCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 WPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE :: .:: ::::: .:: .. .: ::: ..: :.: .: :.:. ::: ::: : CCDS10 WPPSSPGPPETTARPTPGAAPVP------PALYSSPSPQAVQVGGTASLHCDVSGRPPPA 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF .::::: ..:::..:::... ::::::.:.:::.:::. .:::.:::::::.::.::::: CCDS10 VTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADF 220 230 240 250 260 270 310 320 330 340 350 pF1KB6 PLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDC-GEEQTR---WHFDAQANNCLTF :::::. . : .. : : :: ::: :: . : : . . ::.: : ..:.:: CCDS10 PLSVVQREPARDAAPSIPA----PA-ECL--PDVQACTGPTSPHLVLWHYDPQRGGCMTF 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 TFGHCHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVY : :::::::. :: :: :: :::.::::... :::::. ::. ::: CCDS10 PARGCDGAARGFETYEACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVY 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB6 GGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEP ::::::::::.:::.::..:: :: . ::::. :.::. :.:::::.:.::..:. ::: CCDS10 GGCEGNGNNFHSRESCEDACPVPR-TPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEP 390 400 410 420 430 440 480 490 500 510 520 530 pF1KB6 DS--GRALVTVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVD .. : : :....::::.:::::::: . ::::: .::::::::.:... ::.::::: CCDS10 EAAGGIARVALEDVLKDDKMGLKFLGTKYLEVTLSGMDWACPCPNMTAGDGPLVIMGEVR 450 460 470 480 490 500 540 550 560 570 pF1KB6 GGMAMLRPDSFVGASSARRVRKLREVMHKKTCDVLKEFLGLH :.:.: :.: :.: .::.:. :...:..:..:..: CCDS10 DGVAVLDAGSYVRAASEKRVKKILELLEKQACELLNRFQD 510 520 530 540 576 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:03:27 2016 done: Sat Nov 5 00:03:28 2016 Total Scan time: 2.990 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]