FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6101, 577 aa 1>>>pF1KB6101 577 - 577 aa - 577 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7721+/-0.00125; mu= 6.3459+/- 0.073 mean_var=175.2237+/-38.236, 0's: 0 Z-trim(105.8): 176 B-trim: 17 in 1/50 Lambda= 0.096890 statistics sampled from 8406 (8601) to 8406 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.264), width: 16 Scan time: 2.760 The best scores are: opt bits E(32554) CCDS14133.1 TBL1X gene_id:6907|Hs108|chrX ( 577) 3893 557.5 1.7e-158 CCDS48078.1 TBL1X gene_id:6907|Hs108|chrX ( 526) 3539 508.0 1.2e-143 CCDS14779.1 TBL1Y gene_id:90665|Hs108|chrY ( 522) 3249 467.4 1.9e-131 CCDS46961.1 TBL1XR1 gene_id:79718|Hs108|chr3 ( 514) 2486 360.8 2.4e-99 >>CCDS14133.1 TBL1X gene_id:6907|Hs108|chrX (577 aa) initn: 3893 init1: 3893 opt: 3893 Z-score: 2959.2 bits: 557.5 E(32554): 1.7e-158 Smith-Waterman score: 3893; 100.0% identity (100.0% similar) in 577 aa overlap (1-577:1-577) 10 20 30 40 50 60 pF1KB6 MTELAGASSSCCHRPAGRGAMQSVLHHFQRLRGREGGSHFINTSSPRGEAKMSITSDEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MTELAGASSSCCHRPAGRGAMQSVLHHFQRLRGREGGSHFINTSSPRGEAKMSITSDEVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GVSHQNPSKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GVSHQNPSKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLAS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 ASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLV 490 500 510 520 530 540 550 560 570 pF1KB6 HSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK ::::::::::::::::::::::::::::::::::::: CCDS14 HSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 550 560 570 >>CCDS48078.1 TBL1X gene_id:6907|Hs108|chrX (526 aa) initn: 3539 init1: 3539 opt: 3539 Z-score: 2692.3 bits: 508.0 E(32554): 1.2e-143 Smith-Waterman score: 3539; 100.0% identity (100.0% similar) in 526 aa overlap (52-577:1-526) 30 40 50 60 70 80 pF1KB6 QSVLHHFQRLRGREGGSHFINTSSPRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGI :::::::::::::::::::::::::::::: CCDS48 MSITSDEVNFLVYRYLQESGFSHSAFTFGI 10 20 30 90 100 110 120 130 140 pF1KB6 ESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 ESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPD 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 VVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 VVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENR 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 AHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 AHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 NENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 NENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNL 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB6 ASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 ASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQN 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB6 NTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 NTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSM 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB6 KQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 KQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB6 TKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 TKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKV 460 470 480 490 500 510 570 pF1KB6 GASASDGSVCVLDLRK :::::::::::::::: CCDS48 GASASDGSVCVLDLRK 520 >>CCDS14779.1 TBL1Y gene_id:90665|Hs108|chrY (522 aa) initn: 2645 init1: 2645 opt: 3249 Z-score: 2473.3 bits: 467.4 E(32554): 1.9e-131 Smith-Waterman score: 3249; 91.0% identity (96.6% similar) in 524 aa overlap (52-575:1-522) 30 40 50 60 70 80 pF1KB6 QSVLHHFQRLRGREGGSHFINTSSPRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGI :::::::::::::::::::::::::::::: CCDS14 MSITSDEVNFLVYRYLQESGFSHSAFTFGI 10 20 30 90 100 110 120 130 140 pF1KB6 ESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPD ::::::::::::::::.::::::::::::::::::::.::::::.::::::::: ::.:: CCDS14 ESHISQSNINGTLVPPSALISILQKGLQYVEAEISINKDGTVFDSRPIESLSLIVAVIPD 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 VVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENR ::: ::::: :::.::::::::. :.: : ::: : :..:.::: :::::::::::: CCDS14 VVQMRQQAFGEKLTQQQASAAATE--ASAMAKAATMTPAAISQQNPPKNREATVNGEENG 100 110 120 130 140 210 220 230 240 250 260 pF1KB6 AHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL :: .:::.:::::::.:::: .:::::::::::::::::::::::::::::::::::::: CCDS14 AHEINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL 150 160 170 180 190 200 270 280 290 300 310 320 pF1KB6 NENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNL ::::::::::::::::::::::::::::::::::::..::::: ::::::::::::.::: CCDS14 NENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNL 210 220 230 240 250 260 330 340 350 360 370 380 pF1KB6 ASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQN :::::::::::::::::.::::.::::::::::::::::::::::::::::::::::::: CCDS14 ASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQN 270 280 290 300 310 320 390 400 410 420 430 440 pF1KB6 NTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSM : :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS14 NMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSM 330 340 350 360 370 380 450 460 470 480 490 500 pF1KB6 KQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL ::..:.::::::.::::::::::::::::::::.::::::::::::::::.:.::::::: CCDS14 KQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTL 390 400 410 420 430 440 510 520 530 540 550 560 pF1KB6 TKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKV ::::::::::::::::::::::::: :::::::::.:::::.::::::::::::::::: CCDS14 MKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKV 450 460 470 480 490 500 570 pF1KB6 GASASDGSVCVLDLRK :::::::::::::: CCDS14 GASASDGSVCVLDL 510 520 >>CCDS46961.1 TBL1XR1 gene_id:79718|Hs108|chr3 (514 aa) initn: 2400 init1: 2400 opt: 2486 Z-score: 1897.0 bits: 360.8 E(32554): 2.4e-99 Smith-Waterman score: 3118; 86.3% identity (94.9% similar) in 527 aa overlap (52-577:1-514) 30 40 50 60 70 80 pF1KB6 QSVLHHFQRLRGREGGSHFINTSSPRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGI :::.:::::::::::::::::::::::::: CCDS46 MSISSDEVNFLVYRYLQESGFSHSAFTFGI 10 20 30 90 100 110 120 130 140 pF1KB6 ESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPD :::::::::::.::::::::::.::::::::::.:::::::.:::::::::::::::::: CCDS46 ESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPD 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 VVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENR ::::::::.:.:::::::.::::::::. :.:. .:: : :.::::: CCDS46 VVQTRQQAYRDKLAQQQAAAAAAAAAAA-------------SQQGSAKNGENTANGEENG 100 110 120 130 210 220 230 240 250 260 pF1KB6 AHSV-NNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWN ::.. :::. ::.::.:::: .::.:::::::::::::::::::::::::::::::::: CCDS46 AHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWN 140 150 160 170 180 190 270 280 290 300 310 320 pF1KB6 LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGN :.:::..:::::::::::::::.::::::::::::::..:::::::::::::::::.::: CCDS46 LSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGN 200 210 220 230 240 250 330 340 350 360 370 380 pF1KB6 LASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ ::::::::::::::::::.:::.::::::::::::::::::::::::::::::::::::: CCDS46 LASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ 260 270 280 290 300 310 390 400 410 420 430 440 pF1KB6 NNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWS .:.::::::::::::::.:: :::.:::::::::::::::::.: ::::::::::::::: CCDS46 SNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWS 320 330 340 350 360 370 450 460 470 480 490 500 pF1KB6 MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHT :::. :.::::::::::::::::::::.:.:::.:.:::::::::::::::..::.: :: CCDS46 MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHT 380 390 400 410 420 430 510 520 530 540 550 560 pF1KB6 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDK :::::::::::::::::.:::::::::::::::::.: :::::::::::::::::: ::: CCDS46 LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDK 440 450 460 470 480 490 570 pF1KB6 VGASASDGSVCVLDLRK ::::::::::::::::: CCDS46 VGASASDGSVCVLDLRK 500 510 577 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:53:29 2016 done: Sat Nov 5 10:53:30 2016 Total Scan time: 2.760 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]