FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6117, 621 aa 1>>>pF1KB6117 621 - 621 aa - 621 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3183+/-0.000338; mu= 5.7265+/- 0.021 mean_var=161.4745+/-32.807, 0's: 0 Z-trim(120.0): 66 B-trim: 16 in 3/53 Lambda= 0.100930 statistics sampled from 34723 (34789) to 34723 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.408), width: 16 Scan time: 9.670 The best scores are: opt bits E(85289) NP_004662 (OMIM: 603567) E3 SUMO-protein ligase PI ( 621) 4113 611.0 4e-174 XP_005258436 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 622) 4101 609.2 1.3e-173 XP_006722635 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 660) 4061 603.4 8e-172 NP_001310977 (OMIM: 603567) E3 SUMO-protein ligase ( 612) 4054 602.4 1.5e-171 NP_001310978 (OMIM: 603567) E3 SUMO-protein ligase ( 612) 4054 602.4 1.5e-171 XP_016881559 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 612) 4054 602.4 1.5e-171 XP_016881558 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 612) 4054 602.4 1.5e-171 XP_005258434 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 626) 4054 602.4 1.5e-171 XP_011524560 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 620) 4050 601.8 2.3e-171 XP_006722634 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 661) 4049 601.7 2.7e-171 XP_016881557 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 613) 4042 600.6 5.1e-171 XP_011524561 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 613) 4042 600.6 5.1e-171 NP_001310976 (OMIM: 603567) E3 SUMO-protein ligase ( 613) 4042 600.6 5.1e-171 NP_001310975 (OMIM: 603567) E3 SUMO-protein ligase ( 571) 3692 549.6 1.1e-155 NP_775298 (OMIM: 603567) E3 SUMO-protein ligase PI ( 572) 3670 546.4 9.7e-155 XP_006722636 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 611) 3618 538.9 2e-152 XP_016881561 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 563) 3611 537.8 3.7e-152 NP_001310981 (OMIM: 603567) E3 SUMO-protein ligase ( 563) 3611 537.8 3.7e-152 NP_001310983 (OMIM: 603567) E3 SUMO-protein ligase ( 563) 3611 537.8 3.7e-152 XP_016881560 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 563) 3611 537.8 3.7e-152 NP_001310982 (OMIM: 603567) E3 SUMO-protein ligase ( 563) 3611 537.8 3.7e-152 NP_001310980 (OMIM: 603567) E3 SUMO-protein ligase ( 563) 3611 537.8 3.7e-152 NP_001310987 (OMIM: 603567) E3 SUMO-protein ligase ( 507) 3356 500.7 5.1e-141 NP_001310988 (OMIM: 603567) E3 SUMO-protein ligase ( 498) 3297 492.1 1.9e-138 NP_001310984 (OMIM: 603567) E3 SUMO-protein ligase ( 498) 3297 492.1 1.9e-138 NP_001310986 (OMIM: 603567) E3 SUMO-protein ligase ( 498) 3297 492.1 1.9e-138 NP_001310989 (OMIM: 603567) E3 SUMO-protein ligase ( 405) 2632 395.2 2.3e-109 XP_016878180 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 642) 1842 280.3 1.4e-74 XP_016878179 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 642) 1842 280.3 1.4e-74 XP_016878178 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 644) 1842 280.3 1.4e-74 XP_011520429 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 645) 1842 280.3 1.4e-74 NP_057250 (OMIM: 603566) E3 SUMO-protein ligase PI ( 651) 1842 280.3 1.5e-74 XP_016878177 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 653) 1842 280.3 1.5e-74 NP_001307616 (OMIM: 603566) E3 SUMO-protein ligase ( 653) 1842 280.3 1.5e-74 XP_011520428 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 660) 1842 280.3 1.5e-74 NP_006090 (OMIM: 605987) E3 SUMO-protein ligase PI ( 628) 1813 276.1 2.6e-73 NP_056981 (OMIM: 605989) E3 SUMO-protein ligase PI ( 510) 1178 183.5 1.5e-45 XP_011526362 (OMIM: 605989) PREDICTED: E3 SUMO-pro ( 529) 1178 183.6 1.6e-45 XP_016882357 (OMIM: 605989) PREDICTED: E3 SUMO-pro ( 319) 984 155.2 3.2e-37 XP_011513868 (OMIM: 611196) PREDICTED: zinc finger ( 655) 316 58.1 1.1e-07 XP_005249930 (OMIM: 611196) PREDICTED: zinc finger ( 888) 316 58.2 1.5e-07 XP_005249928 (OMIM: 611196) PREDICTED: zinc finger ( 897) 316 58.2 1.5e-07 NP_113637 (OMIM: 611196) zinc finger MIZ domain-co ( 920) 316 58.2 1.5e-07 XP_005249926 (OMIM: 611196) PREDICTED: zinc finger ( 920) 316 58.2 1.5e-07 XP_005249923 (OMIM: 611196) PREDICTED: zinc finger ( 929) 316 58.2 1.5e-07 XP_005249924 (OMIM: 611196) PREDICTED: zinc finger ( 929) 316 58.2 1.5e-07 XP_005249925 (OMIM: 611196) PREDICTED: zinc finger ( 929) 316 58.2 1.5e-07 XP_016868163 (OMIM: 611196) PREDICTED: zinc finger ( 929) 316 58.2 1.5e-07 XP_016871931 (OMIM: 607159) PREDICTED: zinc finger ( 943) 312 57.6 2.3e-07 XP_011538282 (OMIM: 607159) PREDICTED: zinc finger ( 943) 312 57.6 2.3e-07 >>NP_004662 (OMIM: 603567) E3 SUMO-protein ligase PIAS2 (621 aa) initn: 4113 init1: 4113 opt: 4113 Z-score: 3247.1 bits: 611.0 E(85289): 4e-174 Smith-Waterman score: 4113; 100.0% identity (100.0% similar) in 621 aa overlap (1-621:1-621) 10 20 30 40 50 60 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS 550 560 570 580 590 600 610 620 pF1KB6 RSETGVITSSGSNIPDIISLD ::::::::::::::::::::: NP_004 RSETGVITSSGSNIPDIISLD 610 620 >>XP_005258436 (OMIM: 603567) PREDICTED: E3 SUMO-protein (622 aa) initn: 3781 init1: 3781 opt: 4101 Z-score: 3237.7 bits: 609.2 E(85289): 1.3e-173 Smith-Waterman score: 4101; 99.8% identity (99.8% similar) in 622 aa overlap (1-621:1-622) 10 20 30 40 50 60 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP 490 500 510 520 530 540 550 560 570 580 590 pF1KB6 ISSMSSDLPGLDFLSLIPVDPQ-YCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSS :::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_005 ISSMSSDLPGLDFLSLIPVDPQQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSS 550 560 570 580 590 600 600 610 620 pF1KB6 SRSETGVITSSGSNIPDIISLD :::::::::::::::::::::: XP_005 SRSETGVITSSGSNIPDIISLD 610 620 >>XP_006722635 (OMIM: 603567) PREDICTED: E3 SUMO-protein (660 aa) initn: 4061 init1: 4061 opt: 4061 Z-score: 3205.8 bits: 603.4 E(85289): 8e-172 Smith-Waterman score: 4061; 100.0% identity (100.0% similar) in 613 aa overlap (9-621:48-660) 10 20 30 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLL :::::::::::::::::::::::::::::: XP_006 IPTSNVWSDPVSQHPRQHLVLSVFFILAILNMVSSFRVSELQVLLGFAGRNKSGRKHDLL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 MRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAV 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 AGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLD 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 VLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAET 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB6 SCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQIS 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB6 ISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATT 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB6 SLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLI 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB6 LDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTV 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB6 ASEASKKKVDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASEASKKKVDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVT 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB6 SVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTA 560 570 580 590 600 610 580 590 600 610 620 pF1KB6 SSTSVTTTSSHESSTHVSSSSSRSETGVITSSGSNIPDIISLD ::::::::::::::::::::::::::::::::::::::::::: XP_006 SSTSVTTTSSHESSTHVSSSSSRSETGVITSSGSNIPDIISLD 620 630 640 650 660 >>NP_001310977 (OMIM: 603567) E3 SUMO-protein ligase PIA (612 aa) initn: 4054 init1: 4054 opt: 4054 Z-score: 3200.8 bits: 602.4 E(85289): 1.5e-171 Smith-Waterman score: 4054; 100.0% identity (100.0% similar) in 612 aa overlap (10-621:1-612) 10 20 30 40 50 60 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS 540 550 560 570 580 590 610 620 pF1KB6 RSETGVITSSGSNIPDIISLD ::::::::::::::::::::: NP_001 RSETGVITSSGSNIPDIISLD 600 610 >>NP_001310978 (OMIM: 603567) E3 SUMO-protein ligase PIA (612 aa) initn: 4054 init1: 4054 opt: 4054 Z-score: 3200.8 bits: 602.4 E(85289): 1.5e-171 Smith-Waterman score: 4054; 100.0% identity (100.0% similar) in 612 aa overlap (10-621:1-612) 10 20 30 40 50 60 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS 540 550 560 570 580 590 610 620 pF1KB6 RSETGVITSSGSNIPDIISLD ::::::::::::::::::::: NP_001 RSETGVITSSGSNIPDIISLD 600 610 >>XP_016881559 (OMIM: 603567) PREDICTED: E3 SUMO-protein (612 aa) initn: 4054 init1: 4054 opt: 4054 Z-score: 3200.8 bits: 602.4 E(85289): 1.5e-171 Smith-Waterman score: 4054; 100.0% identity (100.0% similar) in 612 aa overlap (10-621:1-612) 10 20 30 40 50 60 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS 540 550 560 570 580 590 610 620 pF1KB6 RSETGVITSSGSNIPDIISLD ::::::::::::::::::::: XP_016 RSETGVITSSGSNIPDIISLD 600 610 >>XP_016881558 (OMIM: 603567) PREDICTED: E3 SUMO-protein (612 aa) initn: 4054 init1: 4054 opt: 4054 Z-score: 3200.8 bits: 602.4 E(85289): 1.5e-171 Smith-Waterman score: 4054; 100.0% identity (100.0% similar) in 612 aa overlap (10-621:1-612) 10 20 30 40 50 60 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSS 540 550 560 570 580 590 610 620 pF1KB6 RSETGVITSSGSNIPDIISLD ::::::::::::::::::::: XP_016 RSETGVITSSGSNIPDIISLD 600 610 >>XP_005258434 (OMIM: 603567) PREDICTED: E3 SUMO-protein (626 aa) initn: 3734 init1: 3734 opt: 4054 Z-score: 3200.6 bits: 602.4 E(85289): 1.5e-171 Smith-Waterman score: 4054; 99.7% identity (99.8% similar) in 616 aa overlap (7-621:11-626) 10 20 30 40 50 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIK :.:::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNAGKQLQRTLHNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 IRELYRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IRELYRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 PVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 KFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 KLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 RQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 CRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 KFQEDGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KFQEDGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIES 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 SSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPF 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 HHTPISSMSSDLPGLDFLSLIPVDPQ-YCPPMFLDSLTSPLTASSTSVTTTSSHESSTHV :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_005 HHTPISSMSSDLPGLDFLSLIPVDPQQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHV 550 560 570 580 590 600 600 610 620 pF1KB6 SSSSSRSETGVITSSGSNIPDIISLD :::::::::::::::::::::::::: XP_005 SSSSSRSETGVITSSGSNIPDIISLD 610 620 >>XP_011524560 (OMIM: 603567) PREDICTED: E3 SUMO-protein (620 aa) initn: 3730 init1: 3730 opt: 4050 Z-score: 3197.5 bits: 601.8 E(85289): 2.3e-171 Smith-Waterman score: 4050; 99.7% identity (99.8% similar) in 615 aa overlap (8-621:6-620) 10 20 30 40 50 60 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL .:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLPFSQNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTP 480 490 500 510 520 530 550 560 570 580 590 pF1KB6 ISSMSSDLPGLDFLSLIPVDPQ-YCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSS :::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_011 ISSMSSDLPGLDFLSLIPVDPQQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSS 540 550 560 570 580 590 600 610 620 pF1KB6 SRSETGVITSSGSNIPDIISLD :::::::::::::::::::::: XP_011 SRSETGVITSSGSNIPDIISLD 600 610 620 >>XP_006722634 (OMIM: 603567) PREDICTED: E3 SUMO-protein (661 aa) initn: 3729 init1: 3729 opt: 4049 Z-score: 3196.3 bits: 601.7 E(85289): 2.7e-171 Smith-Waterman score: 4049; 99.8% identity (99.8% similar) in 614 aa overlap (9-621:48-661) 10 20 30 pF1KB6 MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLL :::::::::::::::::::::::::::::: XP_006 IPTSNVWSDPVSQHPRQHLVLSVFFILAILNMVSSFRVSELQVLLGFAGRNKSGRKHDLL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 MRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAV 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 AGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLD 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 VLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAET 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB6 SCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQIS 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB6 ISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATT 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB6 SLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLI 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB6 LDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTV 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB6 ASEASKKKVDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASEASKKKVDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVT 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB6 SVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQ-YCPPMFLDSLTSPLT :::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::: XP_006 SVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQQYCPPMFLDSLTSPLT 560 570 580 590 600 610 580 590 600 610 620 pF1KB6 ASSTSVTTTSSHESSTHVSSSSSRSETGVITSSGSNIPDIISLD :::::::::::::::::::::::::::::::::::::::::::: XP_006 ASSTSVTTTSSHESSTHVSSSSSRSETGVITSSGSNIPDIISLD 620 630 640 650 660 621 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:55:27 2016 done: Sat Nov 5 10:55:29 2016 Total Scan time: 9.670 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]