FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6123, 586 aa 1>>>pF1KB6123 586 - 586 aa - 586 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5994+/-0.000881; mu= 17.3353+/- 0.053 mean_var=69.7745+/-13.775, 0's: 0 Z-trim(106.4): 18 B-trim: 0 in 0/51 Lambda= 0.153542 statistics sampled from 8943 (8950) to 8943 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.275), width: 16 Scan time: 3.380 The best scores are: opt bits E(32554) CCDS9112.1 CRY1 gene_id:1407|Hs108|chr12 ( 586) 4079 912.9 0 CCDS7915.2 CRY2 gene_id:1408|Hs108|chr11 ( 614) 2978 669.0 4.7e-192 CCDS44576.1 CRY2 gene_id:1408|Hs108|chr11 ( 532) 2690 605.2 6.7e-173 >>CCDS9112.1 CRY1 gene_id:1407|Hs108|chr12 (586 aa) initn: 4079 init1: 4079 opt: 4079 Z-score: 4879.8 bits: 912.9 E(32554): 0 Smith-Waterman score: 4079; 100.0% identity (100.0% similar) in 586 aa overlap (1-586:1-586) 10 20 30 40 50 60 pF1KB6 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 IERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 IERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYA 490 500 510 520 530 540 550 560 570 580 pF1KB6 HGDSQQTHLLKQGRSSMGTGLSGGKRPSQEEDTQSIGPKVQRQSTN :::::::::::::::::::::::::::::::::::::::::::::: CCDS91 HGDSQQTHLLKQGRSSMGTGLSGGKRPSQEEDTQSIGPKVQRQSTN 550 560 570 580 >>CCDS7915.2 CRY2 gene_id:1408|Hs108|chr11 (614 aa) initn: 2976 init1: 2976 opt: 2978 Z-score: 3561.4 bits: 669.0 E(32554): 4.7e-192 Smith-Waterman score: 2978; 74.8% identity (89.3% similar) in 563 aa overlap (4-566:44-600) 10 20 30 pF1KB6 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRC ..:::::::::::::::: ..:: .:: CCDS79 VAGAVWTVMAATVATAAAVAPAPAPGTDSASSVHWFRKGLRLHDNPALLAAVRGARCVRC 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 VYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNI :::::::::.::.::::::::::: :::::..::::::::::.:::::::::::::::.. CCDS79 VYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGV 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 TKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRF :.:..::::::::::::::: :.: ::::::... ::::::::.:::::: .:::::::: CCDS79 TRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRF 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 QTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGG :..::.:: . :: .::. .:.: . ....::: ::::::::::: :.::. ::: :: CCDS79 QAIISRMELPKKPVGLVTSQQMESCRAEIQENHDETYGVPSLEELGFPTEGLGPAVWQGG 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB6 ETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLY :::::.::..::::::::::.::::::::::::::::::::::::::::::::..: ::: CCDS79 ETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLY 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB6 KKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEG ::::.::.:::::.::::::::::::::::::::.:::::::.:::::.::::::::::: CCDS79 KKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEG 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB6 RTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSIN .:::::::::::::::::::::::::::::::::::::.::: :..::.:::::::.:.: CCDS79 KTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVN 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB6 AGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEG ::::::::::.::::::::::::::::::::.::::::::: :..::..:::.::::::. CCDS79 AGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKAFPSRYIYEPWNAPES 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB6 IQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGF :::.:::.:::.::.:.:::::.::::::::::::::::::::: ::::::: . . CCDS79 IQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVED---L 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB6 MGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTGLSGGKRPSQEEDT :: :. :..:: :. .: : .. . :. .. : :: : CCDS79 SHPVAE--PSSSQAGSMSS-AGPRPLPSGPASPKRKLEAAEEPPGEELSKRARVAELPTP 560 570 580 590 600 580 pF1KB6 QSIGPKVQRQSTN CCDS79 ELPSKDA 610 >>CCDS44576.1 CRY2 gene_id:1408|Hs108|chr11 (532 aa) initn: 2685 init1: 2685 opt: 2690 Z-score: 3217.6 bits: 605.2 E(32554): 6.7e-173 Smith-Waterman score: 2690; 74.2% identity (89.5% similar) in 515 aa overlap (52-566:11-518) 30 40 50 60 70 80 pF1KB6 KECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPA : :::: :::::..::::::::::.::::: CCDS44 MPAPPGRTHTW-FLLQSLEDLDTSLRKLNSRLFVVRGQPA 10 20 30 90 100 110 120 130 140 pF1KB6 DVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIEL ::::::::::..:.:..::::::::::::::: :.: ::::::... ::::::::.:::: CCDS44 DVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIEL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 NGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFD :: .:::::::::..::.:: . :: .::. .:.: . ....::: ::::::::::: CCDS44 NGQKPPLTYKRFQAIISRMELPKKPVGLVTSQQMESCRAEIQENHDETYGVPSLEELGFP 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 TDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLS :.::. ::: :::::::.::..::::::::::.::::::::::::::::::::::::::: CCDS44 TEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 CRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWD :::::..: :::::::.::.:::::.::::::::::::::::::::.:::::::.::::: CCDS44 CRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWD 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB6 KNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVF .:::::::::::.:::::::::::::::::::::::::::::::::::::.::: :..:: CCDS44 RNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVF 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB6 EELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPA .:::::::.:.:::::::::::.::::::::::::::::::::.::::::::: :..::. CCDS44 DELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKAFPS 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB6 KYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLA .:::.::::::.:::.:::.:::.::.:.:::::.::::::::::::::::::::: ::: CCDS44 RYIYEPWNAPESIQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLA 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB6 SVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTGL :::: . ... . . :. :..:: :. .: : .. . :. .. : : CCDS44 SVPSCVED----LSHPVAE-PSSSQAGSMSS-AGPRPLPSGPASPKRKLEAAEEPPGEEL 460 470 480 490 500 510 570 580 pF1KB6 SGGKRPSQEEDTQSIGPKVQRQSTN : : CCDS44 SKRARVAELPTPELPSKDA 520 530 586 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:58:04 2016 done: Sat Nov 5 10:58:04 2016 Total Scan time: 3.380 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]