FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6132, 628 aa 1>>>pF1KB6132 628 - 628 aa - 628 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7212+/-0.000833; mu= 14.0769+/- 0.050 mean_var=155.0316+/-31.421, 0's: 0 Z-trim(112.0): 89 B-trim: 62 in 2/53 Lambda= 0.103006 statistics sampled from 12733 (12832) to 12733 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.394), width: 16 Scan time: 4.170 The best scores are: opt bits E(32554) CCDS12644.1 BCAM gene_id:4059|Hs108|chr19 ( 628) 4242 642.6 4.6e-184 CCDS42575.1 BCAM gene_id:4059|Hs108|chr19 ( 588) 3952 599.5 4.1e-171 CCDS31690.1 MCAM gene_id:4162|Hs108|chr11 ( 646) 634 106.5 1.2e-22 >>CCDS12644.1 BCAM gene_id:4059|Hs108|chr19 (628 aa) initn: 4242 init1: 4242 opt: 4242 Z-score: 3418.1 bits: 642.6 E(32554): 4.6e-184 Smith-Waterman score: 4242; 100.0% identity (100.0% similar) in 628 aa overlap (1-628:1-628) 10 20 30 40 50 60 pF1KB6 MEPPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILDCTPTGTHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MEPPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILDCTPTGTHD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HYMLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 HYMLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAAH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRGDGSPSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 YSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRGDGSPSPE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 YTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 YTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 TYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 PKLSWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PKLSWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 SPQTSQAGVAVMAVAVSVGLLLLVVAVFYCVRRKGGPCCRQRREKGAPPPGEPGLSHSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SPQTSQAGVAVMAVAVSVGLLLLVVAVFYCVRRKGGPCCRQRREKGAPPPGEPGLSHSGS 550 560 570 580 590 600 610 620 pF1KB6 EQPEQTGLLMGGASGGARGGSGGFGDEC :::::::::::::::::::::::::::: CCDS12 EQPEQTGLLMGGASGGARGGSGGFGDEC 610 620 >>CCDS42575.1 BCAM gene_id:4059|Hs108|chr19 (588 aa) initn: 3952 init1: 3952 opt: 3952 Z-score: 3185.5 bits: 599.5 E(32554): 4.1e-171 Smith-Waterman score: 3952; 100.0% identity (100.0% similar) in 588 aa overlap (1-588:1-588) 10 20 30 40 50 60 pF1KB6 MEPPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILDCTPTGTHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MEPPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILDCTPTGTHD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HYMLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 HYMLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAAH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRGDGSPSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRGDGSPSPE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 YTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 TYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 PKLSWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PKLSWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 SPQTSQAGVAVMAVAVSVGLLLLVVAVFYCVRRKGGPCCRQRREKGAPPPGEPGLSHSGS :::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SPQTSQAGVAVMAVAVSVGLLLLVVAVFYCVRRKGGPCCRQRREKGAP 550 560 570 580 610 620 pF1KB6 EQPEQTGLLMGGASGGARGGSGGFGDEC >>CCDS31690.1 MCAM gene_id:4162|Hs108|chr11 (646 aa) initn: 548 init1: 163 opt: 634 Z-score: 520.2 bits: 106.5 E(32554): 1.2e-22 Smith-Waterman score: 808; 30.0% identity (55.9% similar) in 676 aa overlap (12-627:2-640) 10 20 30 40 50 pF1KB6 MEPPDAPAQARGAPRLLLLAVLLAAH---P---DAQAEVRLSVPPLVEVMRGKSVILDCT : :::. : :::: : . .:.. .: :::: :....: : CCDS31 MGLPRLVC-AFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCG 10 20 30 40 60 70 80 90 100 pF1KB6 PTGTHDHY-MLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPP--YQ--LDSQGR . .. . ..:: :.. . : ... .:.: : :. :. : : CCDS31 LSQSQGNLSHVDWF------------SVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDR 50 60 70 80 90 110 120 130 140 150 160 pF1KB6 ---LVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSA :.:... ::: ..: .. . : .: :. :: ... : . : CCDS31 GATLALTQVTPQDERIFLC--QGKRPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEP 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB6 QEIATCNSRNGNPAPKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRL .:.::: .::: : :.. ::.::. :. : : ..:.:: :.::: .: : : .: CCDS31 EEVATCVGRNGYPIPQVIWYKNGRPLK--EEKNRVHIQSSQTV-ESSGLYTLQSILKAQL 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB6 RKDDRDASFHCAAHYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDT :.:.::.:.: .: :: : : . .: . . ::::.: :. :.: ..::: CCDS31 VKEDKDAQFYCELNYRLPSGNHMK-ESREVTVPVFYPTEKV--WL--EVEPVGMLKEGDR 220 230 240 250 260 290 300 310 320 330 340 pF1KB6 VQLLCRGDGSPSPEYTLFR----LQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDY :.. : .::.: :.... . .. .::. : : : :.:: . . .:: : :. : CCDS31 VEIRCLADGNPPPHFSISKQNPSTREAEEETTNDN--GVLVLEPARKEHSGRYECQGLDL 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB6 DAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTP :. .. ::. :: : :.. ...: . .:: ...: ... ..: .. : CCDS31 DTMISL-LSEPQELLVNYVSDVRVSPAAPERQE-GSSLTLTCEAESSQDLEFQWLREETG 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB6 --LGDGPMLSLSSITFDSNGTYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKAD : ::.:.: .. ...: : : ::.:..: :.::: .. . : : . : : :. CCDS31 QVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWM--AFKERKV- 390 400 410 420 430 440 470 480 490 500 510 pF1KB6 GSW-REGDEVTLICSARGHPDPKLSWSQLG-GSPAEPIPGRQGWVSSSLTLKVTSALSRD : .:. ..: : : ::: : .::. : .: . : : : :.:.. :: : . CCDS31 --WVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQR---VLSTLNVLVTPELLET 450 460 470 480 490 520 530 540 pF1KB6 GISCEASNPHGNKRHVFHF--------------------GTVSPQTSQA----------- :. : ::: :.. .. . .:.::.: CCDS31 GVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEP 500 510 520 530 540 550 550 560 570 580 590 600 pF1KB6 ---GVAVMAVAVSVGLLLLVVAVFYCVRRKGG-PCCRQRREKGAPPPGEPG---LSHSGS ::...:: : . .: .. ::.: . .:: :: :. ... . ::.. . . ... CCDS31 ESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITLPPSRKSELVVEVKSD 560 570 580 590 600 610 610 620 pF1KB6 EQPEQTGLLMGGASGGARGGSGGFGDEC . ::. :::.: :.: . . : :.. CCDS31 KLPEEMGLLQG--SSGDKRAPGDQGEKYIDLRH 620 630 640 628 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:48:20 2016 done: Fri Nov 4 21:48:20 2016 Total Scan time: 4.170 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]