FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6140, 634 aa 1>>>pF1KB6140 634 - 634 aa - 634 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2838+/-0.000878; mu= 2.2791+/- 0.053 mean_var=195.6327+/-39.383, 0's: 0 Z-trim(113.7): 14 B-trim: 6 in 1/49 Lambda= 0.091697 statistics sampled from 14342 (14350) to 14342 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.441), width: 16 Scan time: 3.720 The best scores are: opt bits E(32554) CCDS77270.1 GATAD2A gene_id:54815|Hs108|chr19 ( 634) 4085 552.8 5.1e-157 CCDS12402.2 GATAD2A gene_id:54815|Hs108|chr19 ( 633) 4068 550.6 2.4e-156 CCDS1054.1 GATAD2B gene_id:57459|Hs108|chr1 ( 593) 810 119.5 1.3e-26 >>CCDS77270.1 GATAD2A gene_id:54815|Hs108|chr19 (634 aa) initn: 4085 init1: 4085 opt: 4085 Z-score: 2932.5 bits: 552.8 E(32554): 5.1e-157 Smith-Waterman score: 4085; 100.0% identity (100.0% similar) in 634 aa overlap (1-634:1-634) 10 20 30 40 50 60 pF1KB6 MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 QVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQAGRMSAATVLSREPYMCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQAGRMSAATVLSREPYMCAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 CKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 CKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 GTAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GTAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 GVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSP 550 560 570 580 590 600 610 620 630 pF1KB6 SLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK :::::::::::::::::::::::::::::::::: CCDS77 SLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK 610 620 630 >>CCDS12402.2 GATAD2A gene_id:54815|Hs108|chr19 (633 aa) initn: 2561 init1: 2561 opt: 4068 Z-score: 2920.4 bits: 550.6 E(32554): 2.4e-156 Smith-Waterman score: 4068; 99.8% identity (99.8% similar) in 634 aa overlap (1-634:1-633) 10 20 30 40 50 60 pF1KB6 MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 QVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQAGRMSAATVLSREPYMCAQ ::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::: CCDS12 LEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQ-GRMSAATVLSREPYMCAQ 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 CKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 CKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 GTAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GTAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPR 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 GVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSP 540 550 560 570 580 590 610 620 630 pF1KB6 SLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK :::::::::::::::::::::::::::::::::: CCDS12 SLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK 600 610 620 630 >>CCDS1054.1 GATAD2B gene_id:57459|Hs108|chr1 (593 aa) initn: 1129 init1: 381 opt: 810 Z-score: 591.5 bits: 119.5 E(32554): 1.3e-26 Smith-Waterman score: 1264; 41.3% identity (62.3% similar) in 666 aa overlap (1-632:4-590) 10 20 30 40 pF1KB6 MTEEACRTRSQKRALERDPTEDDVESKKIKMERG-------LLASDLNTD-GDMRV- :::.: : ::.:. .::: .:..::: .:: : ....: CCDS10 MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVP 10 20 30 40 50 60 50 60 70 80 90 pF1KB6 ----TPEPGAG------PTQGLLRATEATAMAMGR-GEGLVGDGPVDMRTSHSDMKSERR : . :.: .: :: .. . :: :. ..: :::: . .:. . : CCDS10 HELPTKQDGSGVKGYEEKLNGNLRP-HGDNRTAGRPGKENINDEPVDMSARRSEPERGRL 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 PPSPDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEA ::::.::::::: :::: .. :: .. : . .. :::...::::..::::::: CCDS10 TPSPDIIVLSDNEA-SSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEA 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 KLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGS .:::::::::::.::: ..:: :.: :: .: CCDS10 RLVLLKKLRQSQLQKENVVQKT------------PVV---QNA---------------AS 180 190 200 220 230 240 250 260 270 pF1KB6 VIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVP .. : .. :::. ::: . ..: : : .: : ::. ..: : .:.. :. .: CCDS10 IVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAP 210 220 230 240 250 260 280 290 300 310 320 pF1KB6 S-VQIQGQR-IIQQGLIRVANVPNTSLLVNI-PQPTPASLKGTTATSA-----QANSTPT . .:.:::: . ::.:... :: . .: :: . . :..:: .. : CCDS10 NPAQLQGQRGPPKPGLVRTTT-PNMNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPG 270 280 290 300 310 320 330 340 350 360 370 380 pF1KB6 SVASVVTSAESP------ASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNE .: : . :: :. ::::::::::::::::::::::::::: ..:::::::.: CCDS10 TVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSE 330 340 350 360 370 380 390 400 410 420 430 440 pF1KB6 FIYLVGLEEVVQNLLETQAGRMSAATVLSREPYMCAQCKTDFTCRWREEKSGAIMCENCM :::.::::::::.....: :. : :..: ::..::::.:::: .:..::.: :.::.:: CCDS10 FIYMVGLEEVVQSVIDSQ-GK-SCASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCM 390 400 410 420 430 440 450 460 470 480 490 500 pF1KB6 TTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVI :.:::::::.:::.::: :::::::::::::::: :: : ::.:: ....: CCDS10 TSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQ------AALSPTTAP--AVSSVS 450 460 470 480 490 510 520 530 540 550 560 pF1KB6 KPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRGVLHTFSPSPKLQNSASATALVS : .. .: :. . : .:.:.:: :. :..: .:. .:.:. .. .. CCDS10 K--QETIMRHHTLRQ-----APQPQSSLQRGIPTSARSMLSNFAQAPQLSVPGGLLGM-- 500 510 520 530 540 570 580 590 600 610 620 pF1KB6 RTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQREYLLDMIP : : ..:... ... ::. : .:::::::::::: CCDS10 ------------------------P---GVNIAYLNTGIGGHKGPSLADRQREYLLDMIP 550 560 570 580 630 pF1KB6 PRSIPQSATWK :::: :: . CCDS10 PRSISQSISGQK 590 634 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:57:25 2016 done: Fri Nov 4 21:57:26 2016 Total Scan time: 3.720 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]