FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6148, 640 aa 1>>>pF1KB6148 640 - 640 aa - 640 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.4354+/-0.000978; mu= -3.3246+/- 0.059 mean_var=232.2854+/-47.368, 0's: 0 Z-trim(113.2): 12 B-trim: 174 in 1/50 Lambda= 0.084152 statistics sampled from 13870 (13878) to 13870 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.426), width: 16 Scan time: 4.330 The best scores are: opt bits E(32554) CCDS4080.1 ELL2 gene_id:22936|Hs108|chr5 ( 640) 4233 526.8 3.4e-149 CCDS12380.1 ELL gene_id:8178|Hs108|chr19 ( 621) 1298 170.5 6.1e-42 >>CCDS4080.1 ELL2 gene_id:22936|Hs108|chr5 (640 aa) initn: 4233 init1: 4233 opt: 4233 Z-score: 2792.0 bits: 526.8 E(32554): 3.4e-149 Smith-Waterman score: 4233; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KB6 MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKI 550 560 570 580 590 600 610 620 630 640 pF1KB6 KQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS :::::::::::::::::::::::::::::::::::::::: CCDS40 KQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS 610 620 630 640 >>CCDS12380.1 ELL gene_id:8178|Hs108|chr19 (621 aa) initn: 1487 init1: 688 opt: 1298 Z-score: 866.4 bits: 170.5 E(32554): 6.1e-42 Smith-Waterman score: 1883; 47.9% identity (73.6% similar) in 643 aa overlap (9-639:4-620) 10 20 30 40 50 pF1KB6 MAAGGTGGLREEQRYGLSCGRLGQDN-ITVLHVKLTETAIRALETYQSHKNLIPFRPSIQ :.:.. :::::::... . ..:.:::::..:.::.:.:..... . .::::. CCDS12 MAALKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 FQGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQ ::: .: ..::. : :...:.:::::.:.:::::::::::: :: : .:.::: :: CCDS12 FQGSQGHISIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 DKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPE ::::::::.:::: .:. :.:::::.:.::. ::: :: :.::.::.:: ...:.:: CCDS12 DKITVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 RKRSTPMNPANTIRKTHSS-----STISQRPYRDRVIHLLALKAYKKPELLARLQKDGVN :::.::.: :..:::. .: : .::::.::::.:::::. :.: ::: ::::::.. CCDS12 RKRATPINLASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 QKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPS : ::..: ..::::::...:: . ::.: ..:..:.::::::: :.. :. :: ::: CCDS12 QADKDALDGLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 QNAA---GTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGH :... : . :: ..: ::::: .::::: ::: ::::.:.:. :..::. CCDS12 QSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGK 300 310 320 330 340 350 360 370 380 390 400 pF1KB6 LN-PTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPIS-HPPQIVNSNSNSPSTPEGRGTQD :. :..... : :::. : ::.:: .::. . : . ..: CCDS12 LGVPNGREALLPTPGPPAS----TDTLSSSTHLPPRLEPPRAHD--------PLADVSND 360 370 380 390 400 410 420 430 440 450 460 pF1KB6 LPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKH : . : : : . . : :: .: : .: . . : :..: ::::::: CCDS12 L---GHSGRDC--EHGEAAAPAPTVRLGLP---LLTDCAQPSRPHGSPSRSKPKKKSKKH 410 420 430 440 450 470 480 490 500 510 520 pF1KB6 KEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAI-ELPDY :.:.. . .. . .: .. . ..: .. :.. :..: :.. : ::: CCDS12 KDKERAAE------DKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETPDY 460 470 480 490 500 530 540 550 560 570 580 pF1KB6 LIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQN :.:: :: : ::::.::.::::::.::: ::::.: ..::: .:::: ..:: ::.::.. CCDS12 LLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYET 510 520 530 540 550 560 590 600 610 620 630 640 pF1KB6 VHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS .. ..::::.:::... :: .::.::::::.:::::::::.:.::.: ..: CCDS12 TRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQRQLQAWP 570 580 590 600 610 620 640 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:35:40 2016 done: Sat Nov 5 13:35:41 2016 Total Scan time: 4.330 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]