Result of FASTA (omim) for
pF1KB6148
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6148, 640 aa
1>>>pF1KB6148 640 - 640 aa - 640 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.3985+/-0.000408; mu= -9.0177+/- 0.025
mean_var=272.7781+/-56.071, 0's: 0 Z-trim(121.0): 23 B-trim: 1202 in 1/56
Lambda= 0.077655
statistics sampled from 37063 (37086) to 37063 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.435), width: 16
Scan time: 13.100
The best scores are: opt bits E(85289)
NP_036213 (OMIM: 601874) RNA polymerase II elongat ( 640) 4233 487.7 5.5e-137
XP_016864728 (OMIM: 601874) PREDICTED: RNA polymer ( 589) 3871 447.1 8.2e-125
XP_006714638 (OMIM: 601874) PREDICTED: RNA polymer ( 585) 3804 439.6 1.5e-122
XP_016864730 (OMIM: 601874) PREDICTED: RNA polymer ( 508) 3341 387.7 5.4e-107
XP_016864729 (OMIM: 601874) PREDICTED: RNA polymer ( 508) 3341 387.7 5.4e-107
XP_016864731 (OMIM: 601874) PREDICTED: RNA polymer ( 508) 3341 387.7 5.4e-107
XP_016864732 (OMIM: 601874) PREDICTED: RNA polymer ( 455) 2998 349.3 1.8e-95
NP_006523 (OMIM: 600284) RNA polymerase II elongat ( 621) 1298 158.9 5.1e-38
XP_011526632 (OMIM: 600284) PREDICTED: RNA polymer ( 357) 1111 137.8 6.4e-32
XP_016882826 (OMIM: 600284) PREDICTED: RNA polymer ( 337) 635 84.5 6.9e-16
XP_016882825 (OMIM: 600284) PREDICTED: RNA polymer ( 370) 635 84.5 7.5e-16
XP_016882824 (OMIM: 600284) PREDICTED: RNA polymer ( 488) 635 84.5 9.5e-16
NP_079441 (OMIM: 609885) RNA polymerase II elongat ( 397) 437 62.3 3.8e-09
NP_001231663 (OMIM: 610153,610572) MARVEL domain-c ( 546) 299 46.9 0.00023
XP_005248504 (OMIM: 610153,610572) PREDICTED: MARV ( 546) 299 46.9 0.00023
XP_005248503 (OMIM: 610153,610572) PREDICTED: MARV ( 558) 291 46.0 0.00043
NP_001033692 (OMIM: 610153,610572) MARVEL domain-c ( 558) 291 46.0 0.00043
XP_005248502 (OMIM: 610153,610572) PREDICTED: MARV ( 558) 291 46.0 0.00043
>>NP_036213 (OMIM: 601874) RNA polymerase II elongation (640 aa)
initn: 4233 init1: 4233 opt: 4233 Z-score: 2580.3 bits: 487.7 E(85289): 5.5e-137
Smith-Waterman score: 4233; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640)
10 20 30 40 50 60
pF1KB6 MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKI
550 560 570 580 590 600
610 620 630 640
pF1KB6 KQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
::::::::::::::::::::::::::::::::::::::::
NP_036 KQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
610 620 630 640
>>XP_016864728 (OMIM: 601874) PREDICTED: RNA polymerase (589 aa)
initn: 3951 init1: 3871 opt: 3871 Z-score: 2361.7 bits: 447.1 E(85289): 8.2e-125
Smith-Waterman score: 3871; 99.8% identity (99.8% similar) in 589 aa overlap (1-589:1-589)
10 20 30 40 50 60
pF1KB6 MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKI
::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQVV
550 560 570 580
610 620 630 640
pF1KB6 KQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
>>XP_006714638 (OMIM: 601874) PREDICTED: RNA polymerase (585 aa)
initn: 3802 init1: 3802 opt: 3804 Z-score: 2321.2 bits: 439.6 E(85289): 1.5e-122
Smith-Waterman score: 3804; 99.1% identity (99.7% similar) in 581 aa overlap (60-640:5-585)
30 40 50 60 70 80
pF1KB6 LHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLHGLVKIPKNDPLNEVHNFNFYLSNVG
:. ..::::::::::::::::::::::::
XP_006 MDLFFSWSNALVKIPKNDPLNEVHNFNFYLSNVG
10 20 30
90 100 110 120 130 140
pF1KB6 KDNPQGSFDCIQQTFSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDNPQGSFDCIQQTFSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRS
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 TKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDR
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 VIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB6 RDWPGYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDWPGYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDP
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB6 LMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPP
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB6 QIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPK
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB6 PMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGG
400 410 420 430 440 450
510 520 530 540 550 560
pF1KB6 VKEDCTASMEPSAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKEDCTASMEPSAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRF
460 470 480 490 500 510
570 580 590 600 610 620
pF1KB6 IKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIG
520 530 540 550 560 570
630 640
pF1KB6 EFDQQQAESWS
:::::::::::
XP_006 EFDQQQAESWS
580
>>XP_016864730 (OMIM: 601874) PREDICTED: RNA polymerase (508 aa)
initn: 3341 init1: 3341 opt: 3341 Z-score: 2041.8 bits: 387.7 E(85289): 5.4e-107
Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 508 aa overlap (133-640:1-508)
110 120 130 140 150 160
pF1KB6 TFSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGK
::::::::::::::::::::::::::::::
XP_016 MTRERMTQAEEESRNRSTKVIKPGGPYVGK
10 20 30
170 180 190 200 210 220
pF1KB6 RVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKP
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 ELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRS
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 LESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTN
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB6 RVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB6 EGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKS
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB6 KKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSA
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB6 IELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPG
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB6 SKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
460 470 480 490 500
>>XP_016864729 (OMIM: 601874) PREDICTED: RNA polymerase (508 aa)
initn: 3341 init1: 3341 opt: 3341 Z-score: 2041.8 bits: 387.7 E(85289): 5.4e-107
Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 508 aa overlap (133-640:1-508)
110 120 130 140 150 160
pF1KB6 TFSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGK
::::::::::::::::::::::::::::::
XP_016 MTRERMTQAEEESRNRSTKVIKPGGPYVGK
10 20 30
170 180 190 200 210 220
pF1KB6 RVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKP
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 ELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRS
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 LESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTN
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB6 RVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB6 EGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKS
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB6 KKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSA
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB6 IELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPG
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB6 SKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
460 470 480 490 500
>>XP_016864731 (OMIM: 601874) PREDICTED: RNA polymerase (508 aa)
initn: 3341 init1: 3341 opt: 3341 Z-score: 2041.8 bits: 387.7 E(85289): 5.4e-107
Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 508 aa overlap (133-640:1-508)
110 120 130 140 150 160
pF1KB6 TFSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGK
::::::::::::::::::::::::::::::
XP_016 MTRERMTQAEEESRNRSTKVIKPGGPYVGK
10 20 30
170 180 190 200 210 220
pF1KB6 RVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKP
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 ELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRS
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 LESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTN
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB6 RVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB6 EGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKS
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB6 KKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSA
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB6 IELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPG
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB6 SKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
460 470 480 490 500
>>XP_016864732 (OMIM: 601874) PREDICTED: RNA polymerase (455 aa)
initn: 2998 init1: 2998 opt: 2998 Z-score: 1834.9 bits: 349.3 E(85289): 1.8e-95
Smith-Waterman score: 2998; 100.0% identity (100.0% similar) in 455 aa overlap (186-640:1-455)
160 170 180 190 200 210
pF1KB6 GGPYVGKRVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLA
::::::::::::::::::::::::::::::
XP_016 MNPANTIRKTHSSSTISQRPYRDRVIHLLA
10 20 30
220 230 240 250 260 270
pF1KB6 LKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGY
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB6 SEIDRRSLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEIDRRSLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKA
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB6 RISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSN
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB6 SNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENH
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB6 SMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCT
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB6 ASMEPSAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASMEPSAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQ
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB6 RKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQ
400 410 420 430 440 450
640
pF1KB6 AESWS
:::::
XP_016 AESWS
>>NP_006523 (OMIM: 600284) RNA polymerase II elongation (621 aa)
initn: 1487 init1: 688 opt: 1298 Z-score: 803.5 bits: 158.9 E(85289): 5.1e-38
Smith-Waterman score: 1883; 47.9% identity (73.6% similar) in 643 aa overlap (9-639:4-620)
10 20 30 40 50
pF1KB6 MAAGGTGGLREEQRYGLSCGRLGQDN-ITVLHVKLTETAIRALETYQSHKNLIPFRPSIQ
:.:.. :::::::... . ..:.:::::..:.::.:.:..... . .::::.
NP_006 MAALKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIR
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 FQGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQ
::: .: ..::. : :...:.:::::.:.:::::::::::: :: : .:.::: ::
NP_006 FQGSQGHISIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 DKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPE
::::::::.:::: .:. :.:::::.:.::. ::: :: :.::.::.:: ...:.::
NP_006 DKITVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 RKRSTPMNPANTIRKTHSS-----STISQRPYRDRVIHLLALKAYKKPELLARLQKDGVN
:::.::.: :..:::. .: : .::::.::::.:::::. :.: ::: ::::::..
NP_006 RKRATPINLASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 QKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPS
: ::..: ..::::::...:: . ::.: ..:..:.::::::: :.. :. :: :::
NP_006 QADKDALDGLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 QNAA---GTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGH
:... : . :: ..: ::::: .::::: ::: ::::.:.:. :..::.
NP_006 QSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGK
300 310 320 330 340 350
360 370 380 390 400
pF1KB6 LN-PTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPIS-HPPQIVNSNSNSPSTPEGRGTQD
:. :..... : :::. : ::.:: .::. . : . ..:
NP_006 LGVPNGREALLPTPGPPAS----TDTLSSSTHLPPRLEPPRAHD--------PLADVSND
360 370 380 390 400
410 420 430 440 450 460
pF1KB6 LPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKH
: . : : : . . : :: .: : .: . . : :..: :::::::
NP_006 L---GHSGRDC--EHGEAAAPAPTVRLGLP---LLTDCAQPSRPHGSPSRSKPKKKSKKH
410 420 430 440 450
470 480 490 500 510 520
pF1KB6 KEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAI-ELPDY
:.:.. . .. . .: .. . ..: .. :.. :..: :.. : :::
NP_006 KDKERAAE------DKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETPDY
460 470 480 490 500
530 540 550 560 570 580
pF1KB6 LIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQN
:.:: :: : ::::.::.::::::.::: ::::.: ..::: .:::: ..:: ::.::..
NP_006 LLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYET
510 520 530 540 550 560
590 600 610 620 630 640
pF1KB6 VHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
.. ..::::.:::... :: .::.::::::.:::::::::.:.::.: ..:
NP_006 TRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
570 580 590 600 610 620
>>XP_011526632 (OMIM: 600284) PREDICTED: RNA polymerase (357 aa)
initn: 1089 init1: 676 opt: 1111 Z-score: 694.1 bits: 137.8 E(85289): 6.4e-32
Smith-Waterman score: 1111; 49.6% identity (77.8% similar) in 351 aa overlap (9-351:4-349)
10 20 30 40 50
pF1KB6 MAAGGTGGLREEQRYGLSCGRLGQDN-ITVLHVKLTETAIRALETYQSHKNLIPFRPSIQ
:.:.. :::::::... . ..:.:::::..:.::.:.:..... . .::::.
XP_011 MAALKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIR
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 FQGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQ
::: .: ..::. : :...:.:::::.:.:::::::::::: :: : .:.::: ::
XP_011 FQGSQGHISIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 DKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPE
::::::::.:::: .:. :.:::::.:.::. ::: :: :.::.::.:: ...:.::
XP_011 DKITVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 RKRSTPMNPANTIRKTHSS-----STISQRPYRDRVIHLLALKAYKKPELLARLQKDGVN
:::.::.: :..:::. .: : .::::.::::.:::::. :.: ::: ::::::..
XP_011 RKRATPINLASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 QKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPS
: ::..: ..::::::...:: . ::.: ..:..:.::::::: :.. :. :: :. .
XP_011 QADKDALDGLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVREHSSW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 QNAAGTSRSES--PVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHL
... :. .:. : .. : ..::. :.... : . :. : .::
XP_011 STSLRTGLQEDCWPHLHAQTMVLL-SRRLITSRLVESKMLSL----HVEAASPSQAGGHS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB6 NPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPV
XP_011 AALQILL
>>XP_016882826 (OMIM: 600284) PREDICTED: RNA polymerase (337 aa)
initn: 756 init1: 522 opt: 635 Z-score: 406.3 bits: 84.5 E(85289): 6.9e-16
Smith-Waterman score: 793; 41.2% identity (65.8% similar) in 357 aa overlap (288-639:5-336)
260 270 280 290 300 310
pF1KB6 YTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAA---GTSRSESPVCSSRDAV
:::: :... : . :: ..
XP_016 MASSSRKLCQPQSTGSLLGDPAASSPPGERGRSA
10 20 30
320 330 340 350 360 370
pF1KB6 SSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLN-PTSEKSAAGLPLPPAAAAIP
: ::::: .::::: ::: ::::.:.:. :..::.:. :..... : :::.
XP_016 SPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGREALLPTPGPPAS----
40 50 60 70 80 90
380 390 400 410 420 430
pF1KB6 TPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRT
: ::.:: :.. ...: . ..:: . : : : . . :
XP_016 TDTLSSSTHLP----PRLEPPRAHDPLADV---SNDL---GHSGRDC--EHGEAAAPAPT
100 110 120 130
440 450 460 470 480 490
pF1KB6 SLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKRE
:: .: : .: . . : :..: ::::::::.:.. . .. . .:
XP_016 VRLGLP---LLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAE------DKPRAQLPDC
140 150 160 170 180
500 510 520 530 540 550
pF1KB6 EEIAKLNNSSPNSSGGVKEDCTASMEPSAI-ELPDYLIKYIAIVSYEQRQNYKDDFNAEY
.. . ..: .. :.. :..: :.. : ::::.:: :: : ::::.::.::::::
XP_016 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
190 200 210 220 230 240
560 570 580 590 600 610
pF1KB6 DEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKY
.::: ::::.: ..::: .:::: ..:: ::.::.... ..::::.:::... :: .::.
XP_016 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKH
250 260 270 280 290 300
620 630 640
pF1KB6 RCEYLHNKLAHIKRLIGEFDQQQAESWS
::::::.:::::::::.:.::.: ..:
XP_016 RCEYLHSKLAHIKRLIAEYDQRQLQAWP
310 320 330
640 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:35:41 2016 done: Sat Nov 5 13:35:43 2016
Total Scan time: 13.100 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]