Result of FASTA (ccds) for pF1KB6151
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6151, 596 aa
  1>>>pF1KB6151 596 - 596 aa - 596 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8452+/-0.00105; mu= 15.6100+/- 0.063
 mean_var=60.4364+/-12.236, 0's: 0 Z-trim(102.9): 22  B-trim: 243 in 1/49
 Lambda= 0.164978
 statistics sampled from 7148 (7163) to 7148 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.581), E-opt: 0.2 (0.22), width:  16
 Scan time:  2.100

The best scores are:                                      opt bits E(32554)
CCDS9231.1 VPS33A gene_id:65082|Hs108|chr12        ( 596) 3897 936.4       0
CCDS10369.1 VPS33B gene_id:26276|Hs108|chr15       ( 617)  525 133.8 6.3e-31
CCDS73783.1 VPS33B gene_id:26276|Hs108|chr15       ( 590)  464 119.3 1.4e-26


>>CCDS9231.1 VPS33A gene_id:65082|Hs108|chr12             (596 aa)
 initn: 3897 init1: 3897 opt: 3897  Z-score: 5006.5  bits: 936.4 E(32554):    0
Smith-Waterman score: 3897; 100.0% identity (100.0% similar) in 596 aa overlap (1-596:1-596)

               10        20        30        40        50        60
pF1KB6 MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 EKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 EKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 CEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 CEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 TLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 TLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 ATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 ATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 DKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 DKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 IKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 IKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 NPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 NPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPG
              490       500       510       520       530       540

              550       560       570       580       590      
pF1KB6 ENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 ENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF
              550       560       570       580       590      

>>CCDS10369.1 VPS33B gene_id:26276|Hs108|chr15            (617 aa)
 initn: 825 init1: 315 opt: 525  Z-score: 668.7  bits: 133.8 E(32554): 6.3e-31
Smith-Waterman score: 990; 31.6% identity (63.0% similar) in 621 aa overlap (11-593:14-614)

                  10        20        30        40        50       
pF1KB6    MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKE
                    ....:.. .: .:  .:..  :.: .  .  : .:.  ::. :.::.
CCDS10 MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQ
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB6 HEVEKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRR
       :::.:.. .. :.   .. ... :.::::.. :  ::  : ..   : :: ....: :..
CCDS10 HEVDKLYKVE-NKPALSSNEQLCFLVRPRIKNMRYIASLVNADKLAGRTRKYKVIFSPQK
               70         80        90       100       110         

       120       130       140       150       160       170       
pF1KB6 SLLCEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAK
          ::. :.. :. :. .  .:....:.:.: ::::::    :.. .:::::  .  .:.
CCDS10 FYACEMVLEEEGIYGD-VSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQ
     120       130        140       150       160       170        

       180       190       200       210       220       230       
pF1KB6 GLMTLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLL
       .:  :..::: .:. .: :.::... ..   ...:  :  ..  : . ...::::.::..
CCDS10 ALHLLSTLYGPFPNCYGIGRCAKMAYELWRNLEEEEDGETKGRRPEIGHIFLLDRDVDFV
      180       190       200       210       220       230        

       240       250       260       270       280       290       
pF1KB6 TPLATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYA
       : : .:..::::.:. . :. . : . ::  .  :           . :. ::. .... 
CCDS10 TALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDK-----------SLKVLLNAEDKVFN
      240       250       260       270                  280       

       300       310       320       330       340        350      
pF1KB6 EIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQ-LPHMQAARGSLANHTS
       :::...:. : . ::.::. ..: ...:..   . ..:.:::: :  ..  .  :. : .
CCDS10 EIRNEHFSNVFGFLSQKARNLQAQYDRRRGMD-IKQMKNFVSQELKGLKQEHRLLSLHIG
       290       300       310        320       330       340      

        360       370       380       390       400       410      
pF1KB6 IAELIKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVC
         : :    :..:: . . .:. .. :..  . ..:::. : .. : :. :::.:: :. 
CCDS10 ACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSIT
        350       360       370       380       390       400      

        420       430       440       450                          
pF1KB6 NSGLKQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGG-----------------
       ..::  :     : . ::.:: ::.::. ::..::::  :. :                 
CCDS10 ENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDK
        410       420       430       440       450       460      

                   460       470          480       490        500 
pF1KB6 --------------RNNYPTIRKTLRLW--MD-DVNEQNPTDISYVYSG-YAPLSVRLA-
                     :.:. .: : : :   .: . . . : :..::..: :.::: :.  
CCDS10 AAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFGGAYVPLSCRIIE
        470       480       490       500       510       520      

              510       520       530       540        550         
pF1KB6 QLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPGEN-RVTLIFFLGGVTFAEIA
       :.: : .:....::.:.:    :     .    .. .  .:. :. :. :::: ::.::.
CCDS10 QVLERRSWQGLDEVVRLLNCSDFA----FTDMTKEDKASSESLRLILVVFLGGCTFSEIS
        530       540       550           560       570       580  

     560       570       580       590      
pF1KB6 ALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF
       :::::..  . : .... :: . :..  .::. :   
CCDS10 ALRFLGR--EKGYRFIFLTTAVTNSARLMEAMSEVKA
              590       600       610       

>>CCDS73783.1 VPS33B gene_id:26276|Hs108|chr15            (590 aa)
 initn: 773 init1: 315 opt: 464  Z-score: 590.6  bits: 119.3 E(32554): 1.4e-26
Smith-Waterman score: 929; 31.9% identity (62.6% similar) in 580 aa overlap (52-593:28-587)

              30        40        50        60        70        80 
pF1KB6 ELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNRLPAADVKNIIF
                                     : : ..:::.:.. .. :.   .. ... :
CCDS73    MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQQHEVDKLYKVE-NKPALSSNEQLCF
                  10        20        30        40         50      

              90       100       110       120       130       140 
pF1KB6 FVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLLCEQRLKDLGVLGSFIHREEYS
       .::::.. :  ::  : ..   : :: ....: :..   ::. :.. :. :. .  .:..
CCDS73 LVRPRIKNMRYIASLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGD-VSCDEWA
         60        70        80        90       100        110     

             150       160       170       180       190       200 
pF1KB6 LDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYGTIPQIFGKGECARQ
       ..:.:.: ::::::    :.. .:::::  .  .:..:  :..::: .:. .: :.::..
CCDS73 FSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCAKM
         120       130       140       150       160       170     

             210       220       230       240       250       260 
pF1KB6 VANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQLTYEGLIDEIYGIQNSYV
       . ..   ...:  :  ..  : . ...::::.::..: : .:..::::.:. . :. . :
CCDS73 AYELWRNLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSV
         180       190       200       210       220       230     

             270       280       290       300       310       320 
pF1KB6 KLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKIISAA
        . ::  .  :           . :. ::. .... :::...:. : . ::.::. ..: 
CCDS73 DFGPEVTSSDK-----------SLKVLLNAEDKVFNEIRNEHFSNVFGFLSQKARNLQAQ
         240                  250       260       270       280    

             330       340        350       360       370       380
pF1KB6 FEERHNAKTVGEIKQFVSQ-LPHMQAARGSLANHTSIAELIKDVTTSEDFFDKLTVEQEF
       ...:..   . ..:.:::: :  ..  .  :. : .  : :    :..:: . . .:. .
CCDS73 YDRRRGMD-IKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHAL
          290        300       310       320       330       340   

              390       400       410       420       430       440
pF1KB6 MSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYYKREILQTYGYEH
       . :..  . ..:::. : .. : :. :::.:: :. ..::  :     : . ::.:: ::
CCDS73 LEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEH
           350       360       370       380       390       400   

              450                                      460         
pF1KB6 ILTLHNLEKAGLLKPQTGG-------------------------------RNNYPTIRKT
       .::. ::..::::  :. :                               :.:. .: : 
CCDS73 LLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKK
           410       420       430       440       450       460   

     470          480       490        500        510       520    
pF1KB6 LRLW--MD-DVNEQNPTDISYVYSG-YAPLSVRLA-QLLSRPGWRSIEEVLRILPGPHFE
       : :   .: . . . : :..::..: :.::: :.  :.: : .:....::.:.:    : 
CCDS73 LNLIPRVDGEYDLKVPRDMAYVFGGAYVPLSCRIIEQVLERRSWQGLDEVVRLLNCSDFA
           470       480       490       500       510       520   

          530       540        550       560       570       580   
pF1KB6 ERQPLPTGLQKKRQPGEN-RVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMN
           .    .. .  .:. :. :. :::: ::.::.:::::..  . : .... :: . :
CCDS73 ----FTDMTKEDKASSESLRLILVVFLGGCTFSEISALRFLGR--EKGYRFIFLTTAVTN
               530       540       550       560         570       

           590      
pF1KB6 GTSWIEALMEKPF
       ..  .::. :   
CCDS73 SARLMEAMSEVKA
       580       590




596 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:37:03 2016 done: Sat Nov  5 13:37:04 2016
 Total Scan time:  2.100 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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