FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6161, 599 aa 1>>>pF1KB6161 599 - 599 aa - 599 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0042+/-0.000487; mu= 15.9228+/- 0.030 mean_var=98.8974+/-19.749, 0's: 0 Z-trim(110.8): 203 B-trim: 200 in 1/51 Lambda= 0.128968 statistics sampled from 18969 (19215) to 18969 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.578), E-opt: 0.2 (0.225), width: 16 Scan time: 9.220 The best scores are: opt bits E(85289) NP_001035809 (OMIM: 601213) ATP-binding cassette s ( 599) 3971 750.2 4.6e-216 NP_002931 (OMIM: 601213) ATP-binding cassette sub- ( 599) 3971 750.2 4.6e-216 XP_016867188 (OMIM: 167800,211400,219700,277180,60 (1399) 199 48.6 0.00016 XP_011514056 (OMIM: 167800,211400,219700,277180,60 (1399) 199 48.6 0.00016 XP_011514055 (OMIM: 167800,211400,219700,277180,60 (1399) 199 48.6 0.00016 NP_000483 (OMIM: 167800,211400,219700,277180,60242 (1480) 199 48.6 0.00017 XP_011514053 (OMIM: 167800,211400,219700,277180,60 (1510) 199 48.7 0.00017 XP_011541254 (OMIM: 607784) PREDICTED: ATP-binding ( 582) 192 47.0 0.00021 XP_016873610 (OMIM: 607784) PREDICTED: ATP-binding ( 585) 192 47.0 0.00021 NP_071452 (OMIM: 607784) ATP-binding cassette sub- ( 646) 192 47.1 0.00022 NP_001135977 (OMIM: 607784) ATP-binding cassette s ( 646) 192 47.1 0.00022 XP_006717059 (OMIM: 600047) PREDICTED: ATP-binding (2435) 196 48.3 0.00037 NP_001597 (OMIM: 600047) ATP-binding cassette sub- (2436) 196 48.3 0.00037 NP_997698 (OMIM: 600047) ATP-binding cassette sub- (2466) 196 48.3 0.00037 NP_061142 (OMIM: 612503) ATP-binding cassette sub- (1642) 190 47.0 0.00059 NP_758424 (OMIM: 612503) ATP-binding cassette sub- (1642) 190 47.0 0.00059 XP_011528109 (OMIM: 603076) PREDICTED: ATP-binding ( 641) 183 45.4 0.00071 NP_997511 (OMIM: 603076) ATP-binding cassette sub- ( 644) 183 45.4 0.00071 NP_997512 (OMIM: 603076) ATP-binding cassette sub- ( 663) 183 45.4 0.00072 NP_058198 (OMIM: 603076) ATP-binding cassette sub- ( 666) 183 45.4 0.00073 NP_997510 (OMIM: 603076) ATP-binding cassette sub- ( 668) 183 45.4 0.00073 NP_997057 (OMIM: 603076) ATP-binding cassette sub- ( 677) 183 45.4 0.00074 NP_004906 (OMIM: 603076) ATP-binding cassette sub- ( 678) 183 45.4 0.00074 XP_011528108 (OMIM: 603076) PREDICTED: ATP-binding ( 689) 183 45.4 0.00075 NP_001278951 (OMIM: 170260,604571) antigen peptide ( 547) 175 43.9 0.0018 NP_000584 (OMIM: 170260,604571) antigen peptide tr ( 808) 175 44.0 0.0024 NP_001288759 (OMIM: 605250) multidrug resistance-a ( 784) 174 43.8 0.0026 XP_016875811 (OMIM: 605250) PREDICTED: multidrug r ( 816) 174 43.8 0.0027 XP_016875809 (OMIM: 605250) PREDICTED: multidrug r ( 830) 174 43.8 0.0028 NP_001098985 (OMIM: 605250) multidrug resistance-a ( 859) 174 43.8 0.0028 NP_001288758 (OMIM: 605250) multidrug resistance-a (1278) 174 43.9 0.0038 XP_005254082 (OMIM: 605250) PREDICTED: multidrug r (1282) 174 44.0 0.0039 XP_016875808 (OMIM: 605250) PREDICTED: multidrug r (1282) 174 44.0 0.0039 NP_005836 (OMIM: 605250) multidrug resistance-asso (1325) 174 44.0 0.004 XP_016878732 (OMIM: 158343) PREDICTED: multidrug r ( 931) 166 42.4 0.0084 >>NP_001035809 (OMIM: 601213) ATP-binding cassette sub-f (599 aa) initn: 3971 init1: 3971 opt: 3971 Z-score: 4000.1 bits: 750.2 E(85289): 4.6e-216 Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 599 aa overlap (1-599:1-599) 10 20 30 40 50 60 pF1KB6 MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 CIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 ELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 TGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 DVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPS 490 500 510 520 530 540 550 560 570 580 590 pF1KB6 KNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD 550 560 570 580 590 >>NP_002931 (OMIM: 601213) ATP-binding cassette sub-fami (599 aa) initn: 3971 init1: 3971 opt: 3971 Z-score: 4000.1 bits: 750.2 E(85289): 4.6e-216 Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 599 aa overlap (1-599:1-599) 10 20 30 40 50 60 pF1KB6 MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 CIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 ELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 TGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 DVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPS 490 500 510 520 530 540 550 560 570 580 590 pF1KB6 KNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD 550 560 570 580 590 >>XP_016867188 (OMIM: 167800,211400,219700,277180,602421 (1399 aa) initn: 114 init1: 114 opt: 199 Z-score: 202.0 bits: 48.6 E(85289): 0.00016 Smith-Waterman score: 199; 28.3% identity (59.5% similar) in 173 aa overlap (373-535:371-538) 350 360 370 380 390 400 pF1KB6 KKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGG ..... : .:.:::... .. :.:.:.:: XP_016 SNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGK 350 360 370 380 390 400 410 420 430 440 450 pF1KB6 EVPVLNVSYKPQKISPKSTGSVRQLL-------HEKIRDAYTHPQFVTDVMKPLQIENII .:. : .: :.... . . . :.. :. :. : . .::. XP_016 IKHSGRISFCSQ-FSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIV 410 420 430 440 450 460 470 480 490 500 510 pF1KB6 DQEVQ-TLSGGELQRVALALCLGKPADVYLIDEPSAYLD--SEQRLMAARVVKRFILHAK : :::::. :..:: . : ::.::.: : .::: .:.... . : : : :. XP_016 LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCK---LMAN 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB6 KTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNN :: ..: . ::..... XP_016 KTRILVTSK-MEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMGCDSFDQFSAE 520 530 540 550 560 570 >>XP_011514056 (OMIM: 167800,211400,219700,277180,602421 (1399 aa) initn: 114 init1: 114 opt: 199 Z-score: 202.0 bits: 48.6 E(85289): 0.00016 Smith-Waterman score: 199; 28.3% identity (59.5% similar) in 173 aa overlap (373-535:371-538) 350 360 370 380 390 400 pF1KB6 KKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGG ..... : .:.:::... .. :.:.:.:: XP_011 SNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGK 350 360 370 380 390 400 410 420 430 440 450 pF1KB6 EVPVLNVSYKPQKISPKSTGSVRQLL-------HEKIRDAYTHPQFVTDVMKPLQIENII .:. : .: :.... . . . :.. :. :. : . .::. XP_011 IKHSGRISFCSQ-FSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIV 410 420 430 440 450 460 470 480 490 500 510 pF1KB6 DQEVQ-TLSGGELQRVALALCLGKPADVYLIDEPSAYLD--SEQRLMAARVVKRFILHAK : :::::. :..:: . : ::.::.: : .::: .:.... . : : : :. XP_011 LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCK---LMAN 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB6 KTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNN :: ..: . ::..... XP_011 KTRILVTSK-MEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMGCDSFDQFSAE 520 530 540 550 560 570 >>XP_011514055 (OMIM: 167800,211400,219700,277180,602421 (1399 aa) initn: 114 init1: 114 opt: 199 Z-score: 202.0 bits: 48.6 E(85289): 0.00016 Smith-Waterman score: 199; 28.3% identity (59.5% similar) in 173 aa overlap (373-535:371-538) 350 360 370 380 390 400 pF1KB6 KKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGG ..... : .:.:::... .. :.:.:.:: XP_011 SNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGK 350 360 370 380 390 400 410 420 430 440 450 pF1KB6 EVPVLNVSYKPQKISPKSTGSVRQLL-------HEKIRDAYTHPQFVTDVMKPLQIENII .:. : .: :.... . . . :.. :. :. : . .::. XP_011 IKHSGRISFCSQ-FSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIV 410 420 430 440 450 460 470 480 490 500 510 pF1KB6 DQEVQ-TLSGGELQRVALALCLGKPADVYLIDEPSAYLD--SEQRLMAARVVKRFILHAK : :::::. :..:: . : ::.::.: : .::: .:.... . : : : :. XP_011 LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCK---LMAN 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB6 KTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNN :: ..: . ::..... XP_011 KTRILVTSK-MEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMGCDSFDQFSAE 520 530 540 550 560 570 >>NP_000483 (OMIM: 167800,211400,219700,277180,602421) c (1480 aa) initn: 114 init1: 114 opt: 199 Z-score: 201.6 bits: 48.6 E(85289): 0.00017 Smith-Waterman score: 199; 28.3% identity (59.5% similar) in 173 aa overlap (373-535:452-619) 350 360 370 380 390 400 pF1KB6 KKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGG ..... : .:.:::... .. :.:.:.:: NP_000 SNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGK 430 440 450 460 470 480 410 420 430 440 450 pF1KB6 EVPVLNVSYKPQKISPKSTGSVRQLL-------HEKIRDAYTHPQFVTDVMKPLQIENII .:. : .: :.... . . . :.. :. :. : . .::. NP_000 IKHSGRISFCSQ-FSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIV 490 500 510 520 530 540 460 470 480 490 500 510 pF1KB6 DQEVQ-TLSGGELQRVALALCLGKPADVYLIDEPSAYLD--SEQRLMAARVVKRFILHAK : :::::. :..:: . : ::.::.: : .::: .:.... . : : : :. NP_000 LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCK---LMAN 550 560 570 580 590 520 530 540 550 560 570 pF1KB6 KTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNN :: ..: . ::..... NP_000 KTRILVTSK-MEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMGCDSFDQFSAE 600 610 620 630 640 650 >>XP_011514053 (OMIM: 167800,211400,219700,277180,602421 (1510 aa) initn: 114 init1: 114 opt: 199 Z-score: 201.5 bits: 48.7 E(85289): 0.00017 Smith-Waterman score: 199; 28.3% identity (59.5% similar) in 173 aa overlap (373-535:482-649) 350 360 370 380 390 400 pF1KB6 KKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGG ..... : .:.:::... .. :.:.:.:: XP_011 SNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGK 460 470 480 490 500 510 410 420 430 440 450 pF1KB6 EVPVLNVSYKPQKISPKSTGSVRQLL-------HEKIRDAYTHPQFVTDVMKPLQIENII .:. : .: :.... . . . :.. :. :. : . .::. XP_011 IKHSGRISFCSQ-FSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIV 520 530 540 550 560 570 460 470 480 490 500 510 pF1KB6 DQEVQ-TLSGGELQRVALALCLGKPADVYLIDEPSAYLD--SEQRLMAARVVKRFILHAK : :::::. :..:: . : ::.::.: : .::: .:.... . : : : :. XP_011 LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCK---LMAN 580 590 600 610 620 520 530 540 550 560 570 pF1KB6 KTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNN :: ..: . ::..... XP_011 KTRILVTSK-MEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMGCDSFDQFSAE 630 640 650 660 670 680 >>XP_011541254 (OMIM: 607784) PREDICTED: ATP-binding cas (582 aa) initn: 189 init1: 118 opt: 192 Z-score: 200.2 bits: 47.0 E(85289): 0.00021 Smith-Waterman score: 192; 26.2% identity (57.5% similar) in 221 aa overlap (104-316:32-238) 80 90 100 110 120 130 pF1KB6 NLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGK :..:..: .: :::: ..:::: .. .. XP_011 CGFSHAFQKRIVASGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKG 10 20 30 40 50 60 140 150 160 170 180 pF1KB6 YDDPPDWQEILTYFRGSELQNYFTK----ILEDDLKAIIKPQYVDQIPKAAKGTVGSILD .::. : ::.. : : :..::. . :. . . .: ... :. XP_011 --------QILVNGRPRELRT-FRKMSCYIMQDDM---LLPHLT--VLEAMMVSANLKLS 70 80 90 100 190 200 210 220 230 240 pF1KB6 RKDETKTQAI--VCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYL .:.:.: . . . : : .. . ::::. .:.: :. ... ...::::.: : XP_011 EKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB6 DVKQRLKAAITIRSLINPDRYIIVVEHDLS--VLDYLSDFICCLYGVPSAYGVVTMPFSV : . .... ..:: . : :: . :. : ...... . : :::: . XP_011 DSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPY 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB6 REGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEFELAIV .:... : XP_011 LKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSSPEKNEVPAPC 230 240 250 260 270 280 >>XP_016873610 (OMIM: 607784) PREDICTED: ATP-binding cas (585 aa) initn: 189 init1: 118 opt: 192 Z-score: 200.2 bits: 47.0 E(85289): 0.00021 Smith-Waterman score: 192; 26.2% identity (57.5% similar) in 221 aa overlap (104-316:35-241) 80 90 100 110 120 130 pF1KB6 NLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGK :..:..: .: :::: ..:::: .. .. XP_016 ELREVKQLARGHTAGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKG 10 20 30 40 50 60 140 150 160 170 180 pF1KB6 YDDPPDWQEILTYFRGSELQNYFTK----ILEDDLKAIIKPQYVDQIPKAAKGTVGSILD .::. : ::.. : : :..::. . :. . . .: ... :. XP_016 --------QILVNGRPRELRT-FRKMSCYIMQDDM---LLPHLT--VLEAMMVSANLKLS 70 80 90 100 110 190 200 210 220 230 240 pF1KB6 RKDETKTQAI--VCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYL .:.:.: . . . : : .. . ::::. .:.: :. ... ...::::.: : XP_016 EKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB6 DVKQRLKAAITIRSLINPDRYIIVVEHDLS--VLDYLSDFICCLYGVPSAYGVVTMPFSV : . .... ..:: . : :: . :. : ...... . : :::: . XP_016 DSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPY 180 190 200 210 220 230 310 320 330 340 350 360 pF1KB6 REGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEFELAIV .:... : XP_016 LKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSSPEKNEVPAPC 240 250 260 270 280 290 >>NP_071452 (OMIM: 607784) ATP-binding cassette sub-fami (646 aa) initn: 216 init1: 118 opt: 192 Z-score: 199.6 bits: 47.1 E(85289): 0.00022 Smith-Waterman score: 192; 26.2% identity (57.5% similar) in 221 aa overlap (104-316:96-302) 80 90 100 110 120 130 pF1KB6 NLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGK :..:..: .: :::: ..:::: .. .. NP_071 LSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKG 70 80 90 100 110 120 140 150 160 170 180 pF1KB6 YDDPPDWQEILTYFRGSELQNYFTK----ILEDDLKAIIKPQYVDQIPKAAKGTVGSILD .::. : ::.. : : :..::. . :. . . .: ... :. NP_071 --------QILVNGRPRELRT-FRKMSCYIMQDDM---LLPHLT--VLEAMMVSANLKLS 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 RKDETKTQAI--VCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYL .:.:.: . . . : : .. . ::::. .:.: :. ... ...::::.: : NP_071 EKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 DVKQRLKAAITIRSLINPDRYIIVVEHDLS--VLDYLSDFICCLYGVPSAYGVVTMPFSV : . .... ..:: . : :: . :. : ...... . : :::: . NP_071 DSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 REGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEFELAIV .:... : NP_071 LKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSSPEKNEVPAPC 300 310 320 330 340 350 599 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:41:28 2016 done: Sat Nov 5 18:41:30 2016 Total Scan time: 9.220 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]