FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6181, 659 aa 1>>>pF1KB6181 659 - 659 aa - 659 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5355+/-0.000498; mu= 18.2329+/- 0.031 mean_var=85.1876+/-17.025, 0's: 0 Z-trim(109.1): 203 B-trim: 66 in 1/50 Lambda= 0.138959 statistics sampled from 16989 (17231) to 16989 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.544), E-opt: 0.2 (0.202), width: 16 Scan time: 10.600 The best scores are: opt bits E(85289) NP_002849 (OMIM: 170995,616278) ATP-binding casset ( 659) 4344 881.9 0 XP_006710865 (OMIM: 170995,616278) PREDICTED: ATP- ( 683) 4116 836.2 0 XP_016857441 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 3881 789.0 0 XP_016857443 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 3881 789.0 0 XP_016857442 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 3881 789.0 0 XP_011540179 (OMIM: 170995,616278) PREDICTED: ATP- ( 347) 2329 477.7 3.1e-134 NP_001116146 (OMIM: 170995,616278) ATP-binding cas ( 236) 1474 306.2 9.1e-83 NP_005155 (OMIM: 601081) ATP-binding cassette sub- ( 740) 1041 219.7 2.9e-56 XP_011536329 (OMIM: 601081) PREDICTED: ATP-binding ( 740) 1041 219.7 2.9e-56 NP_000024 (OMIM: 300100,300371) ATP-binding casset ( 745) 1031 217.7 1.2e-55 XP_016874481 (OMIM: 601081) PREDICTED: ATP-binding ( 674) 980 207.5 1.3e-52 NP_005041 (OMIM: 603214,614857) ATP-binding casset ( 606) 735 158.3 7.4e-38 XP_005268006 (OMIM: 603214,614857) PREDICTED: ATP- ( 447) 682 147.6 9.3e-35 XP_005268003 (OMIM: 603214,614857) PREDICTED: ATP- ( 447) 682 147.6 9.3e-35 XP_005267996 (OMIM: 603214,614857) PREDICTED: ATP- ( 468) 667 144.6 7.7e-34 XP_005267998 (OMIM: 603214,614857) PREDICTED: ATP- ( 468) 667 144.6 7.7e-34 XP_005267997 (OMIM: 603214,614857) PREDICTED: ATP- ( 468) 667 144.6 7.7e-34 XP_005267999 (OMIM: 603214,614857) PREDICTED: ATP- ( 468) 667 144.6 7.7e-34 XP_011535343 (OMIM: 603214,614857) PREDICTED: ATP- ( 515) 667 144.6 8.3e-34 XP_006720286 (OMIM: 603214,614857) PREDICTED: ATP- ( 519) 661 143.4 1.9e-33 XP_016877023 (OMIM: 603214,614857) PREDICTED: ATP- ( 402) 628 136.7 1.5e-31 XP_016877021 (OMIM: 603214,614857) PREDICTED: ATP- ( 564) 601 131.4 8.6e-30 XP_016877024 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 566 124.3 7.6e-28 XP_016877027 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 566 124.3 7.6e-28 XP_016877031 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 566 124.3 7.6e-28 XP_016877029 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 566 124.3 7.6e-28 XP_016877025 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 566 124.3 7.6e-28 XP_016877030 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 566 124.3 7.6e-28 XP_016877026 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 566 124.3 7.6e-28 XP_016877028 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 566 124.3 7.6e-28 XP_016877022 (OMIM: 603214,614857) PREDICTED: ATP- ( 550) 566 124.4 1.1e-27 XP_016874483 (OMIM: 601081) PREDICTED: ATP-binding ( 375) 563 123.7 1.2e-27 XP_016874482 (OMIM: 601081) PREDICTED: ATP-binding ( 556) 563 123.8 1.7e-27 XP_016877032 (OMIM: 603214,614857) PREDICTED: ATP- ( 329) 531 117.2 9.5e-26 XP_016877020 (OMIM: 603214,614857) PREDICTED: ATP- ( 572) 471 105.4 6.1e-22 XP_016877033 (OMIM: 603214,614857) PREDICTED: ATP- ( 309) 300 70.9 7.9e-12 NP_001276972 (OMIM: 170261,604571) antigen peptide ( 686) 265 64.1 1.9e-09 NP_000535 (OMIM: 170261,604571) antigen peptide tr ( 703) 264 64.0 2.2e-09 XP_005253346 (OMIM: 239850,601439,608569,614050) P (1536) 267 64.8 2.7e-09 XP_006719088 (OMIM: 239850,601439,608569,614050) P (1536) 267 64.8 2.7e-09 NP_005680 (OMIM: 111600,605452,609153,614497,61540 ( 842) 257 62.6 6.7e-09 XP_016874593 (OMIM: 605453) PREDICTED: ATP-binding ( 485) 245 60.0 2.3e-08 NP_001229942 (OMIM: 605453) ATP-binding cassette s ( 703) 245 60.1 3.1e-08 XP_011536400 (OMIM: 605453) PREDICTED: ATP-binding ( 548) 243 59.7 3.4e-08 XP_005253615 (OMIM: 605453) PREDICTED: ATP-binding ( 548) 243 59.7 3.4e-08 NP_062570 (OMIM: 605453) ATP-binding cassette sub- ( 723) 243 59.8 4.2e-08 XP_016874592 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 243 59.8 4.4e-08 XP_011536398 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 243 59.8 4.4e-08 NP_062571 (OMIM: 605453) ATP-binding cassette sub- ( 766) 243 59.8 4.4e-08 XP_011536397 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 243 59.8 4.4e-08 >>NP_002849 (OMIM: 170995,616278) ATP-binding cassette s (659 aa) initn: 4344 init1: 4344 opt: 4344 Z-score: 4710.3 bits: 881.9 E(85289): 0 Smith-Waterman score: 4344; 100.0% identity (100.0% similar) in 659 aa overlap (1-659:1-659) 10 20 30 40 50 60 pF1KB6 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 VQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 SLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSA 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 VSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS 610 620 630 640 650 >>XP_006710865 (OMIM: 170995,616278) PREDICTED: ATP-bind (683 aa) initn: 4116 init1: 4116 opt: 4116 Z-score: 4463.1 bits: 836.2 E(85289): 0 Smith-Waterman score: 4286; 96.5% identity (96.5% similar) in 683 aa overlap (1-659:1-683) 10 20 30 pF1KB6 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHG----------------------- ::::::::::::::::::::::::::::::::::::: XP_006 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGYFMETWREKSDEVMGELTDHVTH 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 -KKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSR 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 TYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 RLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 YIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNS 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 EEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRP 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 FLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQ 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB6 VLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLI 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB6 RDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTL 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB6 GTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEK 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB6 QRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYY 610 620 630 640 650 660 640 650 pF1KB6 LHMDGRGNYEFKQITEDTVEFGS ::::::::::::::::::::::: XP_006 LHMDGRGNYEFKQITEDTVEFGS 670 680 >>XP_016857441 (OMIM: 170995,616278) PREDICTED: ATP-bind (586 aa) initn: 3881 init1: 3881 opt: 3881 Z-score: 4209.4 bits: 789.0 E(85289): 0 Smith-Waterman score: 3881; 100.0% identity (100.0% similar) in 586 aa overlap (74-659:1-586) 50 60 70 80 90 100 pF1KB6 PLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWM :::::::::::::::::::::::::::::: XP_016 MVPRTFCKETGYLVLIAVMLVSRTYCDVWM 10 20 30 110 120 130 140 150 160 pF1KB6 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB6 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB6 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB6 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB6 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB6 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG 520 530 540 550 560 570 650 pF1KB6 NYEFKQITEDTVEFGS :::::::::::::::: XP_016 NYEFKQITEDTVEFGS 580 >>XP_016857443 (OMIM: 170995,616278) PREDICTED: ATP-bind (586 aa) initn: 3881 init1: 3881 opt: 3881 Z-score: 4209.4 bits: 789.0 E(85289): 0 Smith-Waterman score: 3881; 100.0% identity (100.0% similar) in 586 aa overlap (74-659:1-586) 50 60 70 80 90 100 pF1KB6 PLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWM :::::::::::::::::::::::::::::: XP_016 MVPRTFCKETGYLVLIAVMLVSRTYCDVWM 10 20 30 110 120 130 140 150 160 pF1KB6 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB6 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB6 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB6 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB6 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB6 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG 520 530 540 550 560 570 650 pF1KB6 NYEFKQITEDTVEFGS :::::::::::::::: XP_016 NYEFKQITEDTVEFGS 580 >>XP_016857442 (OMIM: 170995,616278) PREDICTED: ATP-bind (586 aa) initn: 3881 init1: 3881 opt: 3881 Z-score: 4209.4 bits: 789.0 E(85289): 0 Smith-Waterman score: 3881; 100.0% identity (100.0% similar) in 586 aa overlap (74-659:1-586) 50 60 70 80 90 100 pF1KB6 PLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWM :::::::::::::::::::::::::::::: XP_016 MVPRTFCKETGYLVLIAVMLVSRTYCDVWM 10 20 30 110 120 130 140 150 160 pF1KB6 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB6 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB6 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB6 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB6 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB6 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG 520 530 540 550 560 570 650 pF1KB6 NYEFKQITEDTVEFGS :::::::::::::::: XP_016 NYEFKQITEDTVEFGS 580 >>XP_011540179 (OMIM: 170995,616278) PREDICTED: ATP-bind (347 aa) initn: 2329 init1: 2329 opt: 2329 Z-score: 2531.0 bits: 477.7 E(85289): 3.1e-134 Smith-Waterman score: 2329; 100.0% identity (100.0% similar) in 347 aa overlap (313-659:1-347) 290 300 310 320 330 340 pF1KB6 NGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSH :::::::::::::::::::::::::::::: XP_011 MGFIDSIIAKYLATVVGYLVVSRPFLDLSH 10 20 30 350 360 370 380 390 400 pF1KB6 PRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLN 40 50 60 70 80 90 410 420 430 440 450 460 pF1KB6 HGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFE 100 110 120 130 140 150 470 480 490 500 510 520 pF1KB6 VRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQ 160 170 180 190 200 210 530 540 550 560 570 580 pF1KB6 VIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMA 220 230 240 250 260 270 590 600 610 620 630 640 pF1KB6 RLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGR 280 290 300 310 320 330 650 pF1KB6 GNYEFKQITEDTVEFGS ::::::::::::::::: XP_011 GNYEFKQITEDTVEFGS 340 >>NP_001116146 (OMIM: 170995,616278) ATP-binding cassett (236 aa) initn: 1474 init1: 1474 opt: 1474 Z-score: 1607.0 bits: 306.2 E(85289): 9.1e-83 Smith-Waterman score: 1474; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228) 10 20 30 40 50 60 pF1KB6 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVS :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQVLGKILWH 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLV >>NP_005155 (OMIM: 601081) ATP-binding cassette sub-fami (740 aa) initn: 1539 init1: 906 opt: 1041 Z-score: 1131.0 bits: 219.7 E(85289): 2.9e-56 Smith-Waterman score: 1579; 40.3% identity (70.1% similar) in 670 aa overlap (11-650:22-688) 10 20 30 40 pF1KB6 MAAFSKYLTARNSSLAGAAFLLLCL---LHKRRRALGLHGKKSGK--PP : . :..::. : : . :: . : ::::.. : NP_005 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSG-HGKKKAAAYPA 10 20 30 40 50 50 60 70 80 90 pF1KB6 LQNNE----KEGKKERAV--VDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTY .:.: : :. :. ::..:... ::. :. :::.: : .: :.:::. NP_005 AENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTF 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 CDVWMIQ-NGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVR .... .: ...: . . : . . . .. :.: ..::. ..: .: : ::.: NP_005 LSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIP-ATFVNSAIRYLECKLALAFRTR 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 LTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLY :. . :: :. ::::. :.:.:.::::: ::.:. : .::. :::::.::.::..: NP_005 LVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLT 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 IFKL---TSAIGAQ--GPASMMAYLVV--SGLFLTRLRRPIGKMTITEQKYEGEYRYVNS . : ... ::. :: ...: ::: .. : .::.. : . .: :::.: NP_005 SYTLIQTATSRGASPIGP-TLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHS 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB6 RLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGY :.:.: :::::: :.: : . ... .. :..... .. :. . .:.... ::. . : NP_005 RIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGL 300 310 320 330 340 350 340 350 360 370 380 pF1KB6 LVVSRPFLDLS-----HPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLA ..:. :.. . . . . :: : . . .: ..:. ::. . .:.:.:: NP_005 IMVAIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELA 360 370 380 390 400 410 390 400 410 420 430 pF1KB6 GFTARITELMQVLKDLNHGKYERTMVSQQEKG--IEGVQV-IPL---IPGAGEIIIADNI :.:::. ... :. ....: :.:: : :. .. .:..: .:: . :..: .:. NP_005 GYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHG 420 430 440 450 460 470 440 450 460 470 480 490 pF1KB6 IKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTK : ..::. :: :.:. :::.:. : ..:: ::::::::::::.:. :::.. : : : NP_005 IICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYK 480 490 500 510 520 530 500 510 520 530 540 550 pF1KB6 PERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREG : ..::.::::::.::.:::::::::. .:.. :: .: :.. : ::.: ::..::: NP_005 PPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREG 540 550 560 570 580 590 560 570 580 590 600 610 pF1KB6 GWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGIT :::.:.:: :::::::::::.:::.:::::..:.:::::::::.:::: :.. . .::. NP_005 GWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGIS 600 610 620 630 640 650 620 630 640 650 pF1KB6 LFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS :....:: ::::.: . :..::.:...:.:. NP_005 LLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRL 660 670 680 690 700 710 NP_005 NELCKILGEDSVLKTIKNEDETS 720 730 740 >>XP_011536329 (OMIM: 601081) PREDICTED: ATP-binding cas (740 aa) initn: 1539 init1: 906 opt: 1041 Z-score: 1131.0 bits: 219.7 E(85289): 2.9e-56 Smith-Waterman score: 1579; 40.3% identity (70.1% similar) in 670 aa overlap (11-650:22-688) 10 20 30 40 pF1KB6 MAAFSKYLTARNSSLAGAAFLLLCL---LHKRRRALGLHGKKSGK--PP : . :..::. : : . :: . : ::::.. : XP_011 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSG-HGKKKAAAYPA 10 20 30 40 50 50 60 70 80 90 pF1KB6 LQNNE----KEGKKERAV--VDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTY .:.: : :. :. ::..:... ::. :. :::.: : .: :.:::. XP_011 AENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTF 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 CDVWMIQ-NGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVR .... .: ...: . . : . . . .. :.: ..::. ..: .: : ::.: XP_011 LSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIP-ATFVNSAIRYLECKLALAFRTR 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 LTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLY :. . :: :. ::::. :.:.:.::::: ::.:. : .::. :::::.::.::..: XP_011 LVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLT 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 IFKL---TSAIGAQ--GPASMMAYLVV--SGLFLTRLRRPIGKMTITEQKYEGEYRYVNS . : ... ::. :: ...: ::: .. : .::.. : . .: :::.: XP_011 SYTLIQTATSRGASPIGP-TLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHS 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB6 RLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGY :.:.: :::::: :.: : . ... .. :..... .. :. . .:.... ::. . : XP_011 RIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGL 300 310 320 330 340 350 340 350 360 370 380 pF1KB6 LVVSRPFLDLS-----HPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLA ..:. :.. . . . . :: : . . .: ..:. ::. . .:.:.:: XP_011 IMVAIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELA 360 370 380 390 400 410 390 400 410 420 430 pF1KB6 GFTARITELMQVLKDLNHGKYERTMVSQQEKG--IEGVQV-IPL---IPGAGEIIIADNI :.:::. ... :. ....: :.:: : :. .. .:..: .:: . :..: .:. XP_011 GYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHG 420 430 440 450 460 470 440 450 460 470 480 490 pF1KB6 IKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTK : ..::. :: :.:. :::.:. : ..:: ::::::::::::.:. :::.. : : : XP_011 IICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYK 480 490 500 510 520 530 500 510 520 530 540 550 pF1KB6 PERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREG : ..::.::::::.::.:::::::::. .:.. :: .: :.. : ::.: ::..::: XP_011 PPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREG 540 550 560 570 580 590 560 570 580 590 600 610 pF1KB6 GWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGIT :::.:.:: :::::::::::.:::.:::::..:.:::::::::.:::: :.. . .::. XP_011 GWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGIS 600 610 620 630 640 650 620 630 640 650 pF1KB6 LFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS :....:: ::::.: . :..::.:...:.:. XP_011 LLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRL 660 670 680 690 700 710 XP_011 NELCKILGEDSVLKTIKNEDETS 720 730 740 >>NP_000024 (OMIM: 300100,300371) ATP-binding cassette s (745 aa) initn: 1551 init1: 894 opt: 1031 Z-score: 1120.1 bits: 217.7 E(85289): 1.2e-55 Smith-Waterman score: 1561; 40.1% identity (71.3% similar) in 649 aa overlap (32-650:43-684) 10 20 30 40 50 60 pF1KB6 AAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEG-KKERAVVD : ::.. .:.: ..: : .: .. NP_000 NTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAP-AGEP---TQEASGVAAAKAGMN 20 30 40 50 60 70 80 90 100 110 pF1KB6 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQ-NGTLIESGIIGRSR .::..::. .:... ::..:.::: :.: .. :::::. .:.. . .: : . :. .. NP_000 RVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARC-IVRKDP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 KDFKRYLLNFI-AAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNL . : ::... :.: ..::. ..: ..: : :: ::. . :. :.. :::...:. NP_000 RAFGWQLLQWLLIALP-ATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNM 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 DNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLV :.:. :::: ::.:: : ::. :::::.::.::... . : : ..: .. . NP_000 DGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPS-A 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 VSGL--FLT----RLRRP-IGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQT ..:: ::: : : .:... : . .:: ::..::...::::::::.:.. : NP_000 IAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELAL 250 260 270 280 290 300 300 310 320 330 340 pF1KB6 VHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDL-----SHPRHL .. .. :. ... ..: :. . ...... ::. .. : :.:. :.. : . . NP_000 LQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAV 310 320 330 340 350 360 350 360 370 380 390 pF1KB6 KSTHSELLEDYYQSGR---------MLLRMSQALGRIVLAGREMTRLAGFTARITELMQV :.. : :. : : .: ..:. ::. . .:.:.:::.:::. :..:: NP_000 KKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB6 LKDLN--HGKYERTMVSQQEK----GIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPN ..:.. : : : . . : : ::.: . :... ... : ...:..::. NP_000 FEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB6 GDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQR :.:.. .::..:. : ..:: ::::::::::::.:: ::: .:: : :: ..::.::: NP_000 GEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQR 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB6 PYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVL :::..:.:::::::::. ::..::: :. :. :: :.: :::.:::::... :: ::: NP_000 PYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVL 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB6 SGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWK :::::::..:::.:::.:..:.:::::::::.:::: :.. . .::.:....:: :::: NP_000 SGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWK 610 620 630 640 650 660 640 650 pF1KB6 HHEYYLHMDGRGNYEFKQITEDTVEFGS .: . :..::.:...:... NP_000 YHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVA 670 680 690 700 710 720 659 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:15:19 2016 done: Sat Nov 5 09:15:21 2016 Total Scan time: 10.600 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]