FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6187, 660 aa 1>>>pF1KB6187 660 - 660 aa - 660 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1164+/-0.00105; mu= 3.4038+/- 0.063 mean_var=234.1102+/-46.420, 0's: 0 Z-trim(112.2): 35 B-trim: 0 in 0/53 Lambda= 0.083823 statistics sampled from 12993 (13027) to 12993 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.4), width: 16 Scan time: 3.740 The best scores are: opt bits E(32554) CCDS30688.1 SCMH1 gene_id:22955|Hs108|chr1 ( 660) 4556 564.3 1.9e-160 CCDS53302.1 SCMH1 gene_id:22955|Hs108|chr1 ( 599) 4106 509.8 4.3e-144 CCDS53304.1 SCMH1 gene_id:22955|Hs108|chr1 ( 648) 3636 453.0 5.9e-127 CCDS461.1 SCMH1 gene_id:22955|Hs108|chr1 ( 591) 3451 430.6 3e-120 CCDS53301.1 SCMH1 gene_id:22955|Hs108|chr1 ( 577) 3364 420.1 4.3e-117 CCDS53303.1 SCMH1 gene_id:22955|Hs108|chr1 ( 480) 2280 288.9 1.1e-77 CCDS14185.1 SCML2 gene_id:10389|Hs108|chrX ( 700) 1751 225.1 2.6e-58 CCDS5060.2 SCML4 gene_id:256380|Hs108|chr6 ( 414) 785 108.1 2.6e-23 CCDS69163.1 SCML4 gene_id:256380|Hs108|chr6 ( 356) 648 91.5 2.2e-18 CCDS13319.1 L3MBTL1 gene_id:26013|Hs108|chr20 ( 772) 584 84.0 8.6e-16 CCDS46602.2 L3MBTL1 gene_id:26013|Hs108|chr20 ( 840) 584 84.0 9.2e-16 CCDS82238.1 L3MBTL4 gene_id:91133|Hs108|chr18 ( 614) 580 83.4 1e-15 CCDS11839.2 L3MBTL4 gene_id:91133|Hs108|chr18 ( 623) 580 83.4 1e-15 CCDS34538.1 L3MBTL3 gene_id:84456|Hs108|chr6 ( 755) 576 83.0 1.7e-15 CCDS34537.1 L3MBTL3 gene_id:84456|Hs108|chr6 ( 780) 576 83.0 1.7e-15 CCDS14011.1 L3MBTL2 gene_id:83746|Hs108|chr22 ( 705) 467 69.8 1.5e-11 CCDS11581.2 MBTD1 gene_id:54799|Hs108|chr17 ( 628) 462 69.2 2e-11 >>CCDS30688.1 SCMH1 gene_id:22955|Hs108|chr1 (660 aa) initn: 4556 init1: 4556 opt: 4556 Z-score: 2993.9 bits: 564.3 E(32554): 1.9e-160 Smith-Waterman score: 4556; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 610 620 630 640 650 660 >>CCDS53302.1 SCMH1 gene_id:22955|Hs108|chr1 (599 aa) initn: 4106 init1: 4106 opt: 4106 Z-score: 2700.4 bits: 509.8 E(32554): 4.3e-144 Smith-Waterman score: 4106; 100.0% identity (100.0% similar) in 599 aa overlap (62-660:1-599) 40 50 60 70 80 90 pF1KB6 KYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLR :::::::::::::::::::::::::::::: CCDS53 MKLEAQDPRNTTSTCIATVVGLTGARLRLR 10 20 30 100 110 120 130 140 150 pF1KB6 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB6 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB6 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB6 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB6 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS 520 530 540 550 560 570 640 650 660 pF1KB6 DMMMKYMGLKLGPALKLSYHIDRLKQGKF ::::::::::::::::::::::::::::: CCDS53 DMMMKYMGLKLGPALKLSYHIDRLKQGKF 580 590 >>CCDS53304.1 SCMH1 gene_id:22955|Hs108|chr1 (648 aa) initn: 3634 init1: 3634 opt: 3636 Z-score: 2392.7 bits: 453.0 E(32554): 5.9e-127 Smith-Waterman score: 4171; 96.5% identity (96.5% similar) in 636 aa overlap (25-660:35-648) 10 20 30 40 50 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPP :::::::::::::::::::::::::::::: CCDS53 VIDWSDVRKHKYGHLSESASQYQEAADILDLGHFTWDKYLKETCSVPAPVHCFKQSYTPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPIS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 APSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 APSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 LKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 LTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 LPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWT :::::::::::::::: :::::::::::::::::::::: CCDS53 LPPSTASAVRRLCSRG----------------------SDRYLESRDASRLSGRDPSSWT 550 560 570 580 600 610 620 630 640 650 pF1KB6 VEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDR 590 600 610 620 630 640 660 pF1KB6 LKQGKF :::::: CCDS53 LKQGKF >>CCDS461.1 SCMH1 gene_id:22955|Hs108|chr1 (591 aa) initn: 3449 init1: 3449 opt: 3451 Z-score: 2272.4 bits: 430.6 E(32554): 3e-120 Smith-Waterman score: 3986; 96.4% identity (96.4% similar) in 612 aa overlap (49-660:2-591) 20 30 40 50 60 70 pF1KB6 SIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIA :::::::::::::::::::::::::::::: CCDS46 MQSYTPPSNEFKISMKLEAQDPRNTTSTCIA 10 20 30 80 90 100 110 120 130 pF1KB6 TVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPM 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 FLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVL 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 VTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSI 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 HSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRK 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB6 PRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKV 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB6 QQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLP 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB6 AVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 AVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNS 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB6 LARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNER :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRG-------- 460 470 480 490 500 560 570 580 590 600 610 pF1KB6 RDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRK :::::::::::::::::::::::::::::::::::::::::::::: CCDS46 --------------SDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRK 510 520 530 540 620 630 640 650 660 pF1KB6 HEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF :::::::::::::::::::::::::::::::::::::::::: CCDS46 HEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 550 560 570 580 590 >>CCDS53301.1 SCMH1 gene_id:22955|Hs108|chr1 (577 aa) initn: 3362 init1: 3362 opt: 3364 Z-score: 2215.6 bits: 420.1 E(32554): 4.3e-117 Smith-Waterman score: 3899; 96.3% identity (96.3% similar) in 599 aa overlap (62-660:1-577) 40 50 60 70 80 90 pF1KB6 KYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLR :::::::::::::::::::::::::::::: CCDS53 MKLEAQDPRNTTSTCIATVVGLTGARLRLR 10 20 30 100 110 120 130 140 150 pF1KB6 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB6 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB6 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB6 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP ::::::::::::::::::::::::::::::::::::::: CCDS53 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRG--------------------- 460 470 480 580 590 600 610 620 630 pF1KB6 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 -SDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS 490 500 510 520 530 540 640 650 660 pF1KB6 DMMMKYMGLKLGPALKLSYHIDRLKQGKF ::::::::::::::::::::::::::::: CCDS53 DMMMKYMGLKLGPALKLSYHIDRLKQGKF 550 560 570 >>CCDS53303.1 SCMH1 gene_id:22955|Hs108|chr1 (480 aa) initn: 2625 init1: 2104 opt: 2280 Z-score: 1508.3 bits: 288.9 E(32554): 1.1e-77 Smith-Waterman score: 2944; 78.3% identity (78.3% similar) in 612 aa overlap (49-660:2-480) 20 30 40 50 60 70 pF1KB6 SIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIA :::::::::::::::::::::::::::::: CCDS53 MQSYTPPSNEFKISMKLEAQDPRNTTSTCIA 10 20 30 80 90 100 110 120 130 pF1KB6 TVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPM ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPL----------- 40 50 60 70 80 140 150 160 170 180 190 pF1KB6 FLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVL CCDS53 ------------------------------------------------------------ 200 210 220 230 240 250 pF1KB6 VTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSI :::::::::::::::::::: CCDS53 ----------------------------------------VVIPKNPYPASDVNTEKPSI 90 100 260 270 280 290 300 310 pF1KB6 HSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 HSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRK 110 120 130 140 150 160 320 330 340 350 360 370 pF1KB6 PRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKV 170 180 190 200 210 220 380 390 400 410 420 430 pF1KB6 QQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLP 230 240 250 260 270 280 440 450 460 470 480 490 pF1KB6 AVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNS 290 300 310 320 330 340 500 510 520 530 540 550 pF1KB6 LARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNER :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRG-------- 350 360 370 380 390 560 570 580 590 600 610 pF1KB6 RDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRK :::::::::::::::::::::::::::::::::::::::::::::: CCDS53 --------------SDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRK 400 410 420 430 620 630 640 650 660 pF1KB6 HEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF :::::::::::::::::::::::::::::::::::::::::: CCDS53 HEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 440 450 460 470 480 >>CCDS14185.1 SCML2 gene_id:10389|Hs108|chrX (700 aa) initn: 2021 init1: 1179 opt: 1751 Z-score: 1160.3 bits: 225.1 E(32554): 2.6e-58 Smith-Waterman score: 2069; 48.5% identity (72.5% similar) in 676 aa overlap (28-658:33-697) 10 20 30 40 50 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNE : :..::::: :. :: .::.:: :: :. CCDS14 QTVNEDSMDVKKENQEKTPQSSTSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPVND 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 FKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCE ::..:::::.::::.::.:::::.:.::::::::::::::.::::::::: .:::.:.:: CCDS14 FKVGMKLEARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGTCE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 KNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVD :.: .::::::...:.:::::::::::::.::: .:.::::.: : ::.::::::.: CCDS14 KEGDLLQPPLGYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLEAID 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 RKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGT .:::..:::::::.:.:.:: .::::: :::::::..:::::::.::: :::: :::::: CCDS14 KKNPYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQPPGT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 KVVIPKN--PYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISA .: : :: .: .. . :..: ::.: : :. :. ..: . : : .. CCDS14 SVPIVKNIAKTESSPSEASQHSMQSPQKTTLI-LPTQQVRR--SSRIKPPG-----PTAV 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 PSKTAEPLKF-PKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM :.... .. :.:.::. :.:.:: .. :. : . : . . .:.:. : . . CCDS14 PKRSSSVKNITPRKKGPNSGKKEKPLPVICSTSAASLKSLTR-DRGMLYKDVASGPCKIV 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF .. :::.:.::.:. ::::: :..:::::::::. ..:::.. ::::.::: . ::::.. CCDS14 MS-TVCVYVNKHGNFGPHLDPKRIQQLPDHFGPGPVNVVLRRIVQACVDCALETKTVFGY 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB6 LK-QGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQT-- :: ...:::::.: :: : :...:: ::: ...:::::..::.:. :::...:::... CCDS14 LKPDNRGGEVITASFDGETHSIQLPPVNSASFALRFLENFCHSLQCDNLLSSQPFSSSRG 420 430 440 450 460 470 480 490 pF1KB6 HLSLTA-----------IEYSHSHDRY--------------LP--------GETFVLGNS : .: . .: : :: :: . :.: CCDS14 HTHSSAEHDKNQSAKEDVTERQSTKRSPQQTVPYVVPLSPKLPKTKEYASEGEPLFAGGS 480 490 500 510 520 530 500 510 520 530 540 550 pF1KB6 LARSLEPHS-DSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKG-SN . : : :: .:. : : .. . :. :. .. . . .: : .. : CCDS14 AIPKEENLSEDSKSSSLNSGNYLNPACRN-PMYIHTSVSQDFSRSVPGTTSSPLVGDISP 540 550 560 570 580 590 560 570 580 590 600 610 pF1KB6 ERRDMESFWKLNRSPGSDRYLESRDASRLS---GRDPSSWTVEDVMQFVREADPQL-GPH . : ....:. . :. : : :. ..:::.:.:..:.::....:::. :: CCDS14 KSSPHEVKFQMQRKSEAPSYIAVPDPSVLKQGFSKDPSTWSVDEVIQFMKHTDPQISGPL 600 610 620 630 640 650 620 630 640 650 660 pF1KB6 ADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF :::::.::::::::.::.::.::::::::::::::: :.:..::.: CCDS14 ADLFRQHEIDGKALFLLKSDVMMKYMGLKLGPALKLCYYIEKLKEGKYS 660 670 680 690 700 >>CCDS5060.2 SCML4 gene_id:256380|Hs108|chr6 (414 aa) initn: 844 init1: 364 opt: 785 Z-score: 532.1 bits: 108.1 E(32554): 2.6e-23 Smith-Waterman score: 1171; 49.3% identity (71.2% similar) in 416 aa overlap (272-660:2-414) 250 260 270 280 290 pF1KB6 PKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGR-----TPKTLISHPISAP : : ::.:::: :: . : . . CCDS50 MQSQRIPGRKRGRPSLHSTPMKMAVHNLYSA 10 20 30 300 310 320 330 340 350 pF1KB6 SKTAEP-LKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPS-SAM : . : .:.::::: ::: : : :.:..: :: :::::: :..::::::.:: .: CCDS50 SAGSLPAVKIPKKRGRKPGYKIKSRVLMTPLALSPPRSTPEPDLSSIPQDAATVPSLAAP 40 50 60 70 80 90 360 370 380 390 400 410 pF1KB6 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF :: :::.:.::....::.:..:::::::.:::: : :.:::::::::::::..:: :::. CCDS50 QALTVCLYINKQANAGPYLERKKVQQLPEHFGPERPSAVLQQAVQACIDCAHQQKLVFSL 100 110 120 130 140 150 420 430 440 450 460 470 pF1KB6 LKQGHGGEVIS--AVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTH .:::.:::..: : :: .:: .::.:::: :::::: :::..: :.::..::: . CCDS50 VKQGYGGEMVSVSASFDGKQHLRSLPVVNSIGYVLRFLAKLCRSLLCDDLFSHQPFPRGC 160 170 180 190 200 210 480 490 500 510 520 pF1KB6 LSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD-SAS--------NPTNLVSTS . .. . . :. .: . . :. . . :.: ::: .:.. . . CCDS50 SASEKVQ-EKEEGRMESVKTVTTEEYLVNPVGMNRYSVDTSASTFNHRGSLHPSSSLYCK 220 230 240 250 260 270 530 540 550 560 570 pF1KB6 QRHRPLLSSCGLPPSTASAVRR--LCSRGV----LK--GSNERRDMESFWKLNRSPGSDR ... : : .::.. : . : : :. .:. .:. :. . :: .: CCDS50 RQNSGDSHLGGGPAATAGGPRTSPMSSGGPSAPGLRPPASSPKRNTTSL-EGNRCASSPS 280 290 300 310 320 580 590 600 610 620 630 pF1KB6 YLESRDASRLSGRDPSSWTVEDVMQFVREADPQ-LGPHADLFRKHEIDGKALLLLRSDMM ...:: : .:.::.::::::. ::..:::: ::::..:::::::::.:::::.:::. CCDS50 Q-DAQDARRPRSRNPSAWTVEDVVWFVKDADPQALGPHVELFRKHEIDGNALLLLKSDMV 330 340 350 360 370 380 640 650 660 pF1KB6 MKYMGLKLGPALKLSYHIDRLKQGKF :::.:::::::::: ::::.:::.:: CCDS50 MKYLGLKLGPALKLCYHIDKLKQAKF 390 400 410 >>CCDS69163.1 SCML4 gene_id:256380|Hs108|chr6 (356 aa) initn: 770 init1: 364 opt: 648 Z-score: 443.4 bits: 91.5 E(32554): 2.2e-18 Smith-Waterman score: 1034; 49.9% identity (73.0% similar) in 359 aa overlap (323-660:1-356) 300 310 320 330 340 350 pF1KB6 ISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPS- ..: :: :::::: :..::::::.:: CCDS69 MTPLALSPPRSTPEPDLSSIPQDAATVPSL 10 20 30 360 370 380 390 400 410 pF1KB6 SAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTV .: :: :::.:.::....::.:..:::::::.:::: : :.:::::::::::::..:: : CCDS69 AAPQALTVCLYINKQANAGPYLERKKVQQLPEHFGPERPSAVLQQAVQACIDCAHQQKLV 40 50 60 70 80 90 420 430 440 450 460 pF1KB6 FSFLKQGHGGEVIS--AVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFT ::..:::.:::..: : :: .:: .::.:::: :::::: :::..: :.::..::: CCDS69 FSLVKQGYGGEMVSVSASFDGKQHLRSLPVVNSIGYVLRFLAKLCRSLLCDDLFSHQPFP 100 110 120 130 140 150 470 480 490 500 510 520 pF1KB6 QTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD-SAS--------NPTNLV . . .. . . :. .: . . :. . . :.: ::: .:.. . CCDS69 RGCSASEKVQ-EKEEGRMESVKTVTTEEYLVNPVGMNRYSVDTSASTFNHRGSLHPSSSL 160 170 180 190 200 530 540 550 560 570 pF1KB6 STSQRHRPLLSSCGLPPSTASAVRR--LCSRGV----LK--GSNERRDMESFWKLNRSPG .... : : .::.. : . : : :. .:. .:. :. . :: . CCDS69 YCKRQNSGDSHLGGGPAATAGGPRTSPMSSGGPSAPGLRPPASSPKRNTTSL-EGNRCAS 210 220 230 240 250 260 580 590 600 610 620 630 pF1KB6 SDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQ-LGPHADLFRKHEIDGKALLLLRS : ...:: : .:.::.::::::. ::..:::: ::::..:::::::::.:::::.: CCDS69 SPSQ-DAQDARRPRSRNPSAWTVEDVVWFVKDADPQALGPHVELFRKHEIDGNALLLLKS 270 280 290 300 310 320 640 650 660 pF1KB6 DMMMKYMGLKLGPALKLSYHIDRLKQGKF ::.:::.:::::::::: ::::.:::.:: CCDS69 DMVMKYLGLKLGPALKLCYHIDKLKQAKF 330 340 350 >>CCDS13319.1 L3MBTL1 gene_id:26013|Hs108|chr20 (772 aa) initn: 586 init1: 297 opt: 584 Z-score: 397.0 bits: 84.0 E(32554): 8.6e-16 Smith-Waterman score: 584; 41.1% identity (64.7% similar) in 224 aa overlap (14-235:192-413) 10 20 30 40 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAP :. : ..:..::.: .. :: CCDS13 EESEPEAMEKQEEGKDPEGQPTASTPESEEWSSSQPATGEKKECWSWESYLEEQKAITAP 170 180 190 200 210 220 50 60 70 80 90 100 pF1KB6 VHCFK--QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDF : :. :. : .: ::..::::. ::.. . : ::. . : ::::..:: .. .:: CCDS13 VSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDF 230 240 250 260 270 280 110 120 130 140 150 160 pF1KB6 WRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPS : ..: .:.: : ::.: :::: :.. . :: ..: .: :. :: ..: .. : CCDS13 WVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTR--AQAAPKHLFVSQSHS 290 300 310 320 330 170 180 190 200 210 220 pF1KB6 PSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFP : :..::::::::: :: ..: :.. .: :. :: ::.: ..:::: .: : : CCDS13 PPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHP 340 350 360 370 380 390 230 240 250 260 270 280 pF1KB6 VGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKR ::::. : : :: CCDS13 VGWCQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRPPHSFLVNMKLEAVD 400 410 420 430 440 450 660 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:44:20 2016 done: Sat Nov 5 13:44:20 2016 Total Scan time: 3.740 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]