FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6187, 660 aa 1>>>pF1KB6187 660 - 660 aa - 660 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0125+/-0.000408; mu= -2.0193+/- 0.025 mean_var=244.4399+/-50.504, 0's: 0 Z-trim(119.8): 109 B-trim: 44 in 1/56 Lambda= 0.082033 statistics sampled from 34229 (34339) to 34229 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.403), width: 16 Scan time: 11.030 The best scores are: opt bits E(85289) XP_011539335 (OMIM: 616396) PREDICTED: polycomb pr ( 660) 4556 552.6 1.6e-156 NP_001026864 (OMIM: 616396) polycomb protein SCMH1 ( 660) 4556 552.6 1.6e-156 XP_011539334 (OMIM: 616396) PREDICTED: polycomb pr ( 670) 4378 531.6 3.6e-150 XP_006710525 (OMIM: 616396) PREDICTED: polycomb pr ( 670) 4378 531.6 3.6e-150 XP_011539337 (OMIM: 616396) PREDICTED: polycomb pr ( 613) 4193 509.6 1.3e-143 XP_006710527 (OMIM: 616396) PREDICTED: polycomb pr ( 599) 4106 499.3 1.6e-140 NP_001165692 (OMIM: 616396) polycomb protein SCMH1 ( 599) 4106 499.3 1.6e-140 XP_016856188 (OMIM: 616396) PREDICTED: polycomb pr ( 599) 4106 499.3 1.6e-140 XP_011539338 (OMIM: 616396) PREDICTED: polycomb pr ( 599) 4106 499.3 1.6e-140 XP_011539336 (OMIM: 616396) PREDICTED: polycomb pr ( 621) 3788 461.7 3.6e-129 XP_016856187 (OMIM: 616396) PREDICTED: polycomb pr ( 618) 3666 447.3 7.9e-125 XP_011539347 (OMIM: 616396) PREDICTED: polycomb pr ( 569) 3650 445.4 2.8e-124 NP_001165690 (OMIM: 616396) polycomb protein SCMH1 ( 648) 3636 443.7 9.7e-124 XP_016856189 (OMIM: 616396) PREDICTED: polycomb pr ( 564) 3603 439.8 1.3e-122 NP_036368 (OMIM: 616396) polycomb protein SCMH1 is ( 591) 3451 421.8 3.5e-117 XP_011539346 (OMIM: 616396) PREDICTED: polycomb pr ( 492) 3368 411.9 2.7e-114 XP_011539345 (OMIM: 616396) PREDICTED: polycomb pr ( 492) 3368 411.9 2.7e-114 NP_001165689 (OMIM: 616396) polycomb protein SCMH1 ( 577) 3364 411.5 4.3e-114 NP_001165691 (OMIM: 616396) polycomb protein SCMH1 ( 577) 3364 411.5 4.3e-114 XP_011539342 (OMIM: 616396) PREDICTED: polycomb pr ( 523) 3212 393.5 1e-108 XP_016856190 (OMIM: 616396) PREDICTED: polycomb pr ( 559) 3045 373.8 9.7e-103 XP_016856194 (OMIM: 616396) PREDICTED: polycomb pr ( 502) 3022 371.0 5.9e-102 XP_016856195 (OMIM: 616396) PREDICTED: polycomb pr ( 488) 2992 367.4 6.7e-101 XP_016856191 (OMIM: 616396) PREDICTED: polycomb pr ( 547) 2908 357.5 7.2e-98 XP_016856192 (OMIM: 616396) PREDICTED: polycomb pr ( 547) 2908 357.5 7.2e-98 XP_016856198 (OMIM: 616396) PREDICTED: polycomb pr ( 470) 2626 324.1 7.1e-88 XP_016856193 (OMIM: 616396) PREDICTED: polycomb pr ( 537) 2303 285.9 2.6e-76 NP_001165693 (OMIM: 616396) polycomb protein SCMH1 ( 480) 2280 283.2 1.5e-75 XP_016856196 (OMIM: 616396) PREDICTED: polycomb pr ( 480) 2280 283.2 1.5e-75 XP_016856199 (OMIM: 616396) PREDICTED: polycomb pr ( 466) 2250 279.6 1.8e-74 XP_016856202 (OMIM: 616396) PREDICTED: polycomb pr ( 449) 2045 255.3 3.4e-67 XP_016856197 (OMIM: 616396) PREDICTED: polycomb pr ( 479) 2045 255.4 3.6e-67 XP_011539341 (OMIM: 616396) PREDICTED: polycomb pr ( 550) 2045 255.4 4.1e-67 XP_006724521 (OMIM: 300208) PREDICTED: sex comb on ( 609) 1751 220.6 1.3e-56 XP_016884710 (OMIM: 300208) PREDICTED: sex comb on ( 609) 1751 220.6 1.3e-56 NP_006080 (OMIM: 300208) sex comb on midleg-like p ( 700) 1751 220.7 1.5e-56 XP_016884709 (OMIM: 300208) PREDICTED: sex comb on ( 700) 1751 220.7 1.5e-56 XP_016884708 (OMIM: 300208) PREDICTED: sex comb on ( 700) 1751 220.7 1.5e-56 XP_016856201 (OMIM: 616396) PREDICTED: polycomb pr ( 457) 1303 167.5 9.5e-41 XP_016856200 (OMIM: 616396) PREDICTED: polycomb pr ( 457) 1303 167.5 9.5e-41 XP_016884711 (OMIM: 300208) PREDICTED: sex comb on ( 436) 585 82.6 3.5e-15 XP_016881566 (OMIM: 617135) PREDICTED: lethal(3)ma ( 370) 580 81.9 4.6e-15 XP_006722427 (OMIM: 617135) PREDICTED: lethal(3)ma ( 485) 580 82.0 5.7e-15 XP_016881564 (OMIM: 617135) PREDICTED: lethal(3)ma ( 488) 580 82.0 5.7e-15 XP_016881565 (OMIM: 617135) PREDICTED: lethal(3)ma ( 488) 580 82.0 5.7e-15 XP_011524067 (OMIM: 617135) PREDICTED: lethal(3)ma ( 497) 580 82.0 5.8e-15 NP_056293 (OMIM: 608802) lethal(3)malignant brain ( 772) 584 82.6 6e-15 XP_011524065 (OMIM: 617135) PREDICTED: lethal(3)ma ( 521) 580 82.0 6e-15 NP_115479 (OMIM: 608802) lethal(3)malignant brain ( 840) 584 82.6 6.4e-15 XP_011524064 (OMIM: 617135) PREDICTED: lethal(3)ma ( 567) 580 82.0 6.5e-15 >>XP_011539335 (OMIM: 616396) PREDICTED: polycomb protei (660 aa) initn: 4556 init1: 4556 opt: 4556 Z-score: 2930.9 bits: 552.6 E(85289): 1.6e-156 Smith-Waterman score: 4556; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 610 620 630 640 650 660 >>NP_001026864 (OMIM: 616396) polycomb protein SCMH1 iso (660 aa) initn: 4556 init1: 4556 opt: 4556 Z-score: 2930.9 bits: 552.6 E(85289): 1.6e-156 Smith-Waterman score: 4556; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 610 620 630 640 650 660 >>XP_011539334 (OMIM: 616396) PREDICTED: polycomb protei (670 aa) initn: 4378 init1: 4378 opt: 4378 Z-score: 2816.9 bits: 531.6 E(85289): 3.6e-150 Smith-Waterman score: 4378; 100.0% identity (100.0% similar) in 636 aa overlap (25-660:35-670) 10 20 30 40 50 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPP :::::::::::::::::::::::::::::: XP_011 VIDWSDVRKHKYGHLSESASQYQEAADILDLGHFTWDKYLKETCSVPAPVHCFKQSYTPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPIS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 APSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 LKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 LTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 LPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 VEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDR 610 620 630 640 650 660 660 pF1KB6 LKQGKF :::::: XP_011 LKQGKF 670 >>XP_006710525 (OMIM: 616396) PREDICTED: polycomb protei (670 aa) initn: 4378 init1: 4378 opt: 4378 Z-score: 2816.9 bits: 531.6 E(85289): 3.6e-150 Smith-Waterman score: 4378; 100.0% identity (100.0% similar) in 636 aa overlap (25-660:35-670) 10 20 30 40 50 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPP :::::::::::::::::::::::::::::: XP_006 VIDWSDVRKHKYGHLSESASQYQEAADILDLGHFTWDKYLKETCSVPAPVHCFKQSYTPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPIS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 APSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 LKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 LTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 LPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 VEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDR 610 620 630 640 650 660 660 pF1KB6 LKQGKF :::::: XP_006 LKQGKF 670 >>XP_011539337 (OMIM: 616396) PREDICTED: polycomb protei (613 aa) initn: 4193 init1: 4193 opt: 4193 Z-score: 2699.2 bits: 509.6 E(85289): 1.3e-143 Smith-Waterman score: 4193; 100.0% identity (100.0% similar) in 612 aa overlap (49-660:2-613) 20 30 40 50 60 70 pF1KB6 SIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIA :::::::::::::::::::::::::::::: XP_011 MQSYTPPSNEFKISMKLEAQDPRNTTSTCIA 10 20 30 80 90 100 110 120 130 pF1KB6 TVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPM 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 FLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVL 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 VTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSI 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 HSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRK 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB6 PRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKV 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB6 QQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLP 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB6 AVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNS 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB6 LARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNER 460 470 480 490 500 510 560 570 580 590 600 610 pF1KB6 RDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRK 520 530 540 550 560 570 620 630 640 650 660 pF1KB6 HEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF :::::::::::::::::::::::::::::::::::::::::: XP_011 HEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 580 590 600 610 >>XP_006710527 (OMIM: 616396) PREDICTED: polycomb protei (599 aa) initn: 4106 init1: 4106 opt: 4106 Z-score: 2643.7 bits: 499.3 E(85289): 1.6e-140 Smith-Waterman score: 4106; 100.0% identity (100.0% similar) in 599 aa overlap (62-660:1-599) 40 50 60 70 80 90 pF1KB6 KYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLR :::::::::::::::::::::::::::::: XP_006 MKLEAQDPRNTTSTCIATVVGLTGARLRLR 10 20 30 100 110 120 130 140 150 pF1KB6 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB6 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB6 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB6 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB6 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS 520 530 540 550 560 570 640 650 660 pF1KB6 DMMMKYMGLKLGPALKLSYHIDRLKQGKF ::::::::::::::::::::::::::::: XP_006 DMMMKYMGLKLGPALKLSYHIDRLKQGKF 580 590 >>NP_001165692 (OMIM: 616396) polycomb protein SCMH1 iso (599 aa) initn: 4106 init1: 4106 opt: 4106 Z-score: 2643.7 bits: 499.3 E(85289): 1.6e-140 Smith-Waterman score: 4106; 100.0% identity (100.0% similar) in 599 aa overlap (62-660:1-599) 40 50 60 70 80 90 pF1KB6 KYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLR :::::::::::::::::::::::::::::: NP_001 MKLEAQDPRNTTSTCIATVVGLTGARLRLR 10 20 30 100 110 120 130 140 150 pF1KB6 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB6 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB6 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB6 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB6 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS 520 530 540 550 560 570 640 650 660 pF1KB6 DMMMKYMGLKLGPALKLSYHIDRLKQGKF ::::::::::::::::::::::::::::: NP_001 DMMMKYMGLKLGPALKLSYHIDRLKQGKF 580 590 >>XP_016856188 (OMIM: 616396) PREDICTED: polycomb protei (599 aa) initn: 4106 init1: 4106 opt: 4106 Z-score: 2643.7 bits: 499.3 E(85289): 1.6e-140 Smith-Waterman score: 4106; 100.0% identity (100.0% similar) in 599 aa overlap (62-660:1-599) 40 50 60 70 80 90 pF1KB6 KYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLR :::::::::::::::::::::::::::::: XP_016 MKLEAQDPRNTTSTCIATVVGLTGARLRLR 10 20 30 100 110 120 130 140 150 pF1KB6 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB6 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB6 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB6 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB6 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS 520 530 540 550 560 570 640 650 660 pF1KB6 DMMMKYMGLKLGPALKLSYHIDRLKQGKF ::::::::::::::::::::::::::::: XP_016 DMMMKYMGLKLGPALKLSYHIDRLKQGKF 580 590 >>XP_011539338 (OMIM: 616396) PREDICTED: polycomb protei (599 aa) initn: 4106 init1: 4106 opt: 4106 Z-score: 2643.7 bits: 499.3 E(85289): 1.6e-140 Smith-Waterman score: 4106; 100.0% identity (100.0% similar) in 599 aa overlap (62-660:1-599) 40 50 60 70 80 90 pF1KB6 KYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLR :::::::::::::::::::::::::::::: XP_011 MKLEAQDPRNTTSTCIATVVGLTGARLRLR 10 20 30 100 110 120 130 140 150 pF1KB6 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAP 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYW 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPG 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARAS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB6 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB6 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB6 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SASNPTNLVSTSQRHRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSP 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB6 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRS 520 530 540 550 560 570 640 650 660 pF1KB6 DMMMKYMGLKLGPALKLSYHIDRLKQGKF ::::::::::::::::::::::::::::: XP_011 DMMMKYMGLKLGPALKLSYHIDRLKQGKF 580 590 >>XP_011539336 (OMIM: 616396) PREDICTED: polycomb protei (621 aa) initn: 4040 init1: 3788 opt: 3788 Z-score: 2440.0 bits: 461.7 E(85289): 3.6e-129 Smith-Waterman score: 3788; 99.8% identity (100.0% similar) in 549 aa overlap (25-573:35-583) 10 20 30 40 50 pF1KB6 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPP :::::::::::::::::::::::::::::: XP_011 VIDWSDVRKHKYGHLSESASQYQEAADILDLGHFTWDKYLKETCSVPAPVHCFKQSYTPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPIS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 APSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAM 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 LKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 LTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 LPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWT ::::::::::::::::::::::::::::::::::::::. XP_011 LPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGALLSCRVGPIPGEPRCLSTEWP 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 VEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDR XP_011 GPLLMDSRGCDAVCPGS 610 620 660 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:44:20 2016 done: Sat Nov 5 13:44:22 2016 Total Scan time: 11.030 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]