FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6188, 703 aa 1>>>pF1KB6188 703 - 703 aa - 703 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2822+/-0.000856; mu= 3.3426+/- 0.052 mean_var=225.0398+/-45.097, 0's: 0 Z-trim(115.4): 44 B-trim: 165 in 1/55 Lambda= 0.085496 statistics sampled from 15967 (16011) to 15967 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.492), width: 16 Scan time: 4.770 The best scores are: opt bits E(32554) CCDS4737.1 ATF6B gene_id:1388|Hs108|chr6 ( 703) 4718 594.8 1.4e-169 CCDS47408.1 ATF6B gene_id:1388|Hs108|chr6 ( 700) 4677 589.7 4.8e-168 CCDS1235.1 ATF6 gene_id:22926|Hs108|chr1 ( 670) 755 106.0 1.9e-22 >>CCDS4737.1 ATF6B gene_id:1388|Hs108|chr6 (703 aa) initn: 4718 init1: 4718 opt: 4718 Z-score: 3157.8 bits: 594.8 E(32554): 1.4e-169 Smith-Waterman score: 4718; 100.0% identity (100.0% similar) in 703 aa overlap (1-703:1-703) 10 20 30 40 50 60 pF1KB6 MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFRCPEQDVPFDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFRCPEQDVPFDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSEALGVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSEALGVGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSVNSEASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSVNSEASL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LSADSSSQAFIGEEVLEVKTESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LSADSSSQAFIGEEVLEVKTESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 KPPLQPKPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KPPLQPKPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 RPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCIMVFLLFIAFNFGPVSISEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCIMVFLLFIAFNFGPVSISEPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 SAPISPRMNKGEPQPRRHLLGFSEQEPVQGVEPLQGSSQGPKEPQPSPTDQPSFSNLTAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SAPISPRMNKGEPQPRRHLLGFSEQEPVQGVEPLQGSSQGPKEPQPSPTDQPSFSNLTAF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 PGGAKELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKIPQRAQERQKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PGGAKELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKIPQRAQERQKS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 QPRKKSPPVKAVPIQPPGPPERDSVGQLQLYRHPDRSQPAFLDAIDRREDTFYVVSFRRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QPRKKSPPVKAVPIQPPGPPERDSVGQLQLYRHPDRSQPAFLDAIDRREDTFYVVSFRRD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 HLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGAPGDYEEMMQIECEVMDTRVIHIKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 HLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGAPGDYEEMMQIECEVMDTRVIHIKTS 610 620 630 640 650 660 670 680 690 700 pF1KB6 TVPPSLRKQPSPTPGNATGGPLPVSAASQAHQASHQPLYLNHP ::::::::::::::::::::::::::::::::::::::::::: CCDS47 TVPPSLRKQPSPTPGNATGGPLPVSAASQAHQASHQPLYLNHP 670 680 690 700 >>CCDS47408.1 ATF6B gene_id:1388|Hs108|chr6 (700 aa) initn: 4679 init1: 4512 opt: 4677 Z-score: 3130.5 bits: 589.7 E(32554): 4.8e-168 Smith-Waterman score: 4677; 99.4% identity (99.6% similar) in 703 aa overlap (1-703:1-700) 10 20 30 40 50 60 pF1KB6 MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFRCPEQDVPFDG ::::::::::::::::::::::::::: .::::::::::::::::::::::::::::: CCDS47 MAELMLLSEIADPTRFFTDNLLSPEDW---DSTLYSGLDEVAEEQTQLFRCPEQDVPFDG 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 SSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSEALGVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSEALGVGE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSVNSEASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSVNSEASL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 LSADSSSQAFIGEEVLEVKTESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LSADSSSQAFIGEEVLEVKTESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 KPPLQPKPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KPPLQPKPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 RPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 LADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCIMVFLLFIAFNFGPVSISEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCIMVFLLFIAFNFGPVSISEPP 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 SAPISPRMNKGEPQPRRHLLGFSEQEPVQGVEPLQGSSQGPKEPQPSPTDQPSFSNLTAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SAPISPRMNKGEPQPRRHLLGFSEQEPVQGVEPLQGSSQGPKEPQPSPTDQPSFSNLTAF 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 PGGAKELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKIPQRAQERQKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PGGAKELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKIPQRAQERQKS 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 QPRKKSPPVKAVPIQPPGPPERDSVGQLQLYRHPDRSQPAFLDAIDRREDTFYVVSFRRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QPRKKSPPVKAVPIQPPGPPERDSVGQLQLYRHPDRSQPAFLDAIDRREDTFYVVSFRRD 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB6 HLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGAPGDYEEMMQIECEVMDTRVIHIKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 HLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGAPGDYEEMMQIECEVMDTRVIHIKTS 600 610 620 630 640 650 670 680 690 700 pF1KB6 TVPPSLRKQPSPTPGNATGGPLPVSAASQAHQASHQPLYLNHP ::::::::::::::::::::::::::::::::::::::::::: CCDS47 TVPPSLRKQPSPTPGNATGGPLPVSAASQAHQASHQPLYLNHP 660 670 680 690 700 >>CCDS1235.1 ATF6 gene_id:22926|Hs108|chr1 (670 aa) initn: 1021 init1: 416 opt: 755 Z-score: 516.3 bits: 106.0 E(32554): 1.9e-22 Smith-Waterman score: 1099; 34.9% identity (60.3% similar) in 702 aa overlap (25-697:25-666) 10 20 30 40 50 pF1KB6 MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAE-EQTQLFRCPEQ-DVPF ::: .:.:.. : .. .. :: : . : CCDS12 MGEPAGVAGTMESPFSPGLFHRLDEDW---DSALFAELGYFTDTDELQLEAANETYENNF 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 DGSSLDVGMDVSPSEPP-WEL---LPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSE : .:: .:. : : :.. . :.... .: :: .::: : : : :.. : CCDS12 D--NLDFDLDLMPWESDIWDINNQICTVKDIKAEPQPLSP-ASSSYSVSSPR-SVDSYSS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ALGVGEVLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSV . : : : ... : :: : :.. ..:. ... : ..: .::. CCDS12 TQHVPEELDLSSSSQMSPLSLYGEN-SNSLSSAE----PLKED--------KPVTG---- 120 130 140 150 180 190 200 210 220 230 pF1KB6 NSEASLLSADSSSQAFIGEEVLEVKTE-SLSPSGCLLWDVPAPSLGAVQISMGPSLDGSS ... ... .. ..:... :..:. :: :. .: . . CCDS12 -------PRNKTENGLTPKKKIQVNSKPSIQPKPLLL-----PAAPKTQTNSSVPAKTII 160 170 180 190 200 240 250 260 270 280 pF1KB6 GKALPTRKPPLQPKPVVLTTVPMPSRA----VPPSTTVLLQSLVQPPPVSPVVLIQGAIR ...:: : . .:.. . : :... . :.: ::. : ..::. . :.. CCDS12 IQTVPTLMPLAKQQPII-SLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVT 210 220 230 240 250 260 290 300 310 320 330 340 pF1KB6 VQPEG-----PAPSLPRPE--RKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQS :. :::: : . :.. . .. : .:.::::::::::::::: CCDS12 QLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQS 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB6 RRKKKEYLQGLEARLQAVLADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCIMV :.:::::. ::::::.:.:..:.::..::..:.:.:. ...::..::. : .:.:::.:. CCDS12 RKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMI 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB6 FLLFIAFNFGPVSISEPPSAPISPRMNKGEPQPRRHLLGFSEQEPVQGVEPLQGSSQGPK : :: .:.::.:. : : ..: .. .. :::::::: .: : .:.: CCDS12 VLAFIILNYGPMSMLEQDSRRMNPSVSPANQ--RRHLLGFSAKEA-------QDTSDGII 390 400 410 420 430 470 480 490 500 510 520 pF1KB6 EPQPSPTDQPSFSNLTAFPGGAKELLLRDLDQLFLSSD-CRHF-NRTESLRLADELSGWV . . :. : :: :. ..: . :.. :. . : :::::: :: ::: CCDS12 QKNSYRYDH-SVSNDKAL------MVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWV 440 450 460 470 480 530 540 550 560 570 pF1KB6 QRHQRGRRKIPQRAQERQKSQ------PRKKSPPVKAVPI-QPPGPPERDSVGQLQLYRH .::. : : . ....::.. . .. . :: . . :.: ..::.: CCDS12 HRHEVERTKSRRMTNNQQKTRILQGALEQGSNSQLMAVQYTETTSSISRNSGSELQVYYA 490 500 510 520 530 540 580 590 600 610 620 630 pF1KB6 PDRSQPAFLDAIDRREDTFYVVSFRRDHLLLPAISHNKTSRPKMSLVMPAMAPNET-LSG :: :..:: :: ::::::::::::::::: .::::.:::::.:.::. ::. ..: CCDS12 SPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININENVING 550 560 570 580 590 600 640 650 660 670 680 690 pF1KB6 RGAPGDYEEMMQIECEVMDTRVIHIKTSTVPPSLRKQPSPTPGNATGGPLPVSAASQA-H . ::: ::::.:.:::::..:::.:.::: :: : .. :.: : ::..: : CCDS12 Q----DYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSP-P--AATEATH 610 620 630 640 650 660 700 pF1KB6 QASHQPLYLNHP .: : CCDS12 VVSTIPESLQ 670 703 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:45:01 2016 done: Sat Nov 5 13:45:01 2016 Total Scan time: 4.770 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]