FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6193, 662 aa 1>>>pF1KB6193 662 - 662 aa - 662 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2167+/-0.000453; mu= 15.8231+/- 0.028 mean_var=104.7062+/-21.212, 0's: 0 Z-trim(111.1): 107 B-trim: 158 in 1/54 Lambda= 0.125340 statistics sampled from 19480 (19592) to 19480 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.23), width: 16 Scan time: 10.540 The best scores are: opt bits E(85289) XP_005261035 (OMIM: 147150) PREDICTED: interferon- ( 662) 4261 782.0 0 XP_011527870 (OMIM: 147150) PREDICTED: interferon- ( 662) 4261 782.0 0 XP_005261036 (OMIM: 147150) PREDICTED: interferon- ( 662) 4261 782.0 0 XP_005261037 (OMIM: 147150) PREDICTED: interferon- ( 662) 4261 782.0 0 XP_016883838 (OMIM: 147150) PREDICTED: interferon- ( 662) 4261 782.0 0 XP_016883839 (OMIM: 147150) PREDICTED: interferon- ( 662) 4261 782.0 0 NP_001138397 (OMIM: 147150) interferon-induced GTP ( 662) 4261 782.0 0 XP_005261039 (OMIM: 147150) PREDICTED: interferon- ( 662) 4261 782.0 0 XP_005261038 (OMIM: 147150) PREDICTED: interferon- ( 662) 4261 782.0 0 NP_002453 (OMIM: 147150) interferon-induced GTP-bi ( 662) 4261 782.0 0 NP_001171517 (OMIM: 147150) interferon-induced GTP ( 662) 4261 782.0 0 NP_001269849 (OMIM: 147150) interferon-induced GTP ( 508) 2725 504.2 4.8e-142 XP_011527872 (OMIM: 147150) PREDICTED: interferon- ( 483) 2716 502.6 1.4e-141 XP_016883841 (OMIM: 147150) PREDICTED: interferon- ( 609) 2716 502.6 1.7e-141 XP_016883840 (OMIM: 147150) PREDICTED: interferon- ( 609) 2716 502.6 1.7e-141 XP_005261040 (OMIM: 147890) PREDICTED: interferon- ( 715) 2572 476.6 1.3e-133 XP_011527873 (OMIM: 147890) PREDICTED: interferon- ( 715) 2572 476.6 1.3e-133 XP_011527874 (OMIM: 147890) PREDICTED: interferon- ( 715) 2572 476.6 1.3e-133 NP_002454 (OMIM: 147890) interferon-induced GTP-bi ( 715) 2572 476.6 1.3e-133 XP_005261041 (OMIM: 147890) PREDICTED: interferon- ( 715) 2572 476.6 1.3e-133 XP_011527875 (OMIM: 147890) PREDICTED: interferon- ( 670) 2019 376.6 1.6e-103 XP_011527876 (OMIM: 147890) PREDICTED: interferon- ( 417) 1462 275.8 2.3e-73 XP_016869861 (OMIM: 602377,616346) PREDICTED: dyna ( 551) 834 162.3 4.4e-39 XP_016869860 (OMIM: 602377,616346) PREDICTED: dyna ( 851) 834 162.4 6.1e-39 NP_001005336 (OMIM: 602377,616346) dynamin-1 isofo ( 851) 834 162.4 6.1e-39 XP_005251826 (OMIM: 602377,616346) PREDICTED: dyna ( 851) 834 162.4 6.1e-39 NP_001275667 (OMIM: 602377,616346) dynamin-1 isofo ( 851) 834 162.4 6.1e-39 XP_005251825 (OMIM: 602377,616346) PREDICTED: dyna ( 851) 834 162.4 6.1e-39 NP_001275666 (OMIM: 602377,616346) dynamin-1 isofo ( 851) 834 162.4 6.1e-39 XP_016869862 (OMIM: 602377,616346) PREDICTED: dyna ( 861) 834 162.4 6.2e-39 XP_016869859 (OMIM: 602377,616346) PREDICTED: dyna ( 864) 834 162.4 6.2e-39 XP_011516638 (OMIM: 602377,616346) PREDICTED: dyna ( 864) 834 162.4 6.2e-39 NP_004399 (OMIM: 602377,616346) dynamin-1 isoform ( 864) 834 162.4 6.2e-39 XP_011516637 (OMIM: 602377,616346) PREDICTED: dyna ( 864) 834 162.4 6.2e-39 NP_001275668 (OMIM: 602377,616346) dynamin-1 isofo ( 864) 834 162.4 6.2e-39 NP_001005362 (OMIM: 160150,602378,606482,615368) d ( 866) 834 162.4 6.2e-39 XP_016869858 (OMIM: 602377,616346) PREDICTED: dyna ( 867) 834 162.4 6.2e-39 XP_006717055 (OMIM: 602377,616346) PREDICTED: dyna ( 868) 834 162.4 6.2e-39 XP_005251820 (OMIM: 602377,616346) PREDICTED: dyna ( 868) 834 162.4 6.2e-39 NP_001005361 (OMIM: 160150,602378,606482,615368) d ( 870) 834 162.4 6.2e-39 XP_006717056 (OMIM: 602377,616346) PREDICTED: dyna ( 498) 830 161.5 6.7e-39 NP_004936 (OMIM: 160150,602378,606482,615368) dyna ( 866) 823 160.4 2.5e-38 NP_001177645 (OMIM: 160150,602378,606482,615368) d ( 869) 823 160.4 2.5e-38 NP_001005360 (OMIM: 160150,602378,606482,615368) d ( 870) 823 160.4 2.5e-38 NP_001265181 (OMIM: 611445) dynamin-3 isoform c [H ( 555) 812 158.3 6.9e-38 XP_016856480 (OMIM: 611445) PREDICTED: dynamin-3 i ( 564) 812 158.3 7e-38 XP_016856479 (OMIM: 611445) PREDICTED: dynamin-3 i ( 564) 812 158.3 7e-38 XP_006711331 (OMIM: 611445) PREDICTED: dynamin-3 i ( 565) 812 158.3 7e-38 XP_016856478 (OMIM: 611445) PREDICTED: dynamin-3 i ( 568) 812 158.3 7.1e-38 XP_016856477 (OMIM: 611445) PREDICTED: dynamin-3 i ( 593) 812 158.3 7.3e-38 >>XP_005261035 (OMIM: 147150) PREDICTED: interferon-indu (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_005 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: XP_005 PG >>XP_011527870 (OMIM: 147150) PREDICTED: interferon-indu (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_011 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: XP_011 PG >>XP_005261036 (OMIM: 147150) PREDICTED: interferon-indu (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_005 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: XP_005 PG >>XP_005261037 (OMIM: 147150) PREDICTED: interferon-indu (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_005 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: XP_005 PG >>XP_016883838 (OMIM: 147150) PREDICTED: interferon-indu (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_016 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: XP_016 PG >>XP_016883839 (OMIM: 147150) PREDICTED: interferon-indu (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_016 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: XP_016 PG >>NP_001138397 (OMIM: 147150) interferon-induced GTP-bin (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_001 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: NP_001 PG >>XP_005261039 (OMIM: 147150) PREDICTED: interferon-indu (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_005 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: XP_005 PG >>XP_005261038 (OMIM: 147150) PREDICTED: interferon-indu (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_005 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: XP_005 PG >>NP_002453 (OMIM: 147150) interferon-induced GTP-bindin (662 aa) initn: 4261 init1: 4261 opt: 4261 Z-score: 4170.7 bits: 782.0 E(85289): 0 Smith-Waterman score: 4261; 99.8% identity (100.0% similar) in 662 aa overlap (1-662:1-662) 10 20 30 40 50 60 pF1KB6 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_002 GVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQF 610 620 630 640 650 660 pF1KB6 PG :: NP_002 PG 662 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:46:24 2016 done: Sat Nov 5 13:46:25 2016 Total Scan time: 10.540 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]