FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6203, 663 aa 1>>>pF1KB6203 663 - 663 aa - 663 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7022+/-0.000377; mu= 17.7087+/- 0.023 mean_var=75.7447+/-14.781, 0's: 0 Z-trim(113.6): 72 B-trim: 31 in 1/48 Lambda= 0.147366 statistics sampled from 23000 (23068) to 23000 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.27), width: 16 Scan time: 11.060 The best scores are: opt bits E(85289) NP_036519 (OMIM: 180300,605347) protein-arginine d ( 663) 4514 969.5 0 XP_011539452 (OMIM: 180300,605347) PREDICTED: prot ( 601) 3353 722.7 9.7e-208 XP_011539454 (OMIM: 180300,605347) PREDICTED: prot ( 484) 3324 716.4 5.8e-206 NP_037490 (OMIM: 607934) protein-arginine deiminas ( 663) 2592 560.9 5.3e-159 XP_011539453 (OMIM: 180300,605347) PREDICTED: prot ( 563) 2586 559.6 1.1e-158 XP_011539455 (OMIM: 180300,605347) PREDICTED: prot ( 397) 2578 557.8 2.7e-158 XP_011539456 (OMIM: 180300,605347) PREDICTED: prot ( 397) 2578 557.8 2.7e-158 XP_011539458 (OMIM: 180300,605347) PREDICTED: prot ( 386) 2577 557.6 3.1e-158 XP_011539457 (OMIM: 180300,605347) PREDICTED: prot ( 392) 2577 557.6 3.1e-158 XP_011539459 (OMIM: 180300,605347) PREDICTED: prot ( 366) 2547 551.2 2.5e-156 NP_057317 (OMIM: 606755) protein-arginine deiminas ( 664) 2495 540.3 8.6e-153 XP_016856591 (OMIM: 607934) PREDICTED: protein-arg ( 612) 2466 534.1 5.8e-151 XP_016856590 (OMIM: 607934) PREDICTED: protein-arg ( 612) 2466 534.1 5.8e-151 XP_011539873 (OMIM: 606755) PREDICTED: protein-arg ( 626) 2394 518.8 2.4e-146 NP_031391 (OMIM: 607935) protein-arginine deiminas ( 665) 2276 493.7 9e-139 XP_016856952 (OMIM: 606755) PREDICTED: protein-arg ( 485) 2075 450.9 5e-126 XP_016856592 (OMIM: 607934) PREDICTED: protein-arg ( 594) 1851 403.3 1.3e-111 NP_997304 (OMIM: 610363) protein-arginine deiminas ( 694) 1504 329.6 2.4e-89 XP_011539609 (OMIM: 607934) PREDICTED: protein-arg ( 471) 1457 319.5 1.8e-86 XP_016855637 (OMIM: 607935) PREDICTED: protein-arg ( 350) 1444 316.7 9.3e-86 XP_011539874 (OMIM: 606755) PREDICTED: protein-arg ( 421) 1098 243.2 1.5e-63 >>NP_036519 (OMIM: 180300,605347) protein-arginine deimi (663 aa) initn: 4514 init1: 4514 opt: 4514 Z-score: 5183.9 bits: 969.5 E(85289): 0 Smith-Waterman score: 4514; 99.4% identity (100.0% similar) in 663 aa overlap (1-663:1-663) 10 20 30 40 50 60 pF1KB6 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHSPPAKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: NP_036 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCAD :::::::::::::::::::::.:::::::::::::::::::::::::::::.:::::::: NP_036 KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PGGKHNMDFYVEALAFPDTNFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_036 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN 610 620 630 640 650 660 pF1KB6 MVP ::: NP_036 MVP >>XP_011539452 (OMIM: 180300,605347) PREDICTED: protein- (601 aa) initn: 3353 init1: 3353 opt: 3353 Z-score: 3850.6 bits: 722.7 E(85289): 9.7e-208 Smith-Waterman score: 3946; 90.0% identity (90.6% similar) in 663 aa overlap (1-663:1-601) 10 20 30 40 50 60 pF1KB6 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHSPPAKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_011 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCAD :::::::::::::::::::::.:::::::::::::::::::::::::::::.: XP_011 KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGV------- 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM ::::: XP_011 -------------------------------------------------------DLQDM 190 200 210 220 230 240 pF1KB6 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB6 PGGKHNMDFYVEALAFPDTNFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 180 190 200 210 220 230 310 320 330 340 350 360 pF1KB6 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 240 250 260 270 280 290 370 380 390 400 410 420 pF1KB6 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG 300 310 320 330 340 350 430 440 450 460 470 480 pF1KB6 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP 360 370 380 390 400 410 490 500 510 520 530 540 pF1KB6 APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS 420 430 440 450 460 470 550 560 570 580 590 600 pF1KB6 FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK 480 490 500 510 520 530 610 620 630 640 650 660 pF1KB6 PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN 540 550 560 570 580 590 pF1KB6 MVP ::: XP_011 MVP 600 >>XP_011539454 (OMIM: 180300,605347) PREDICTED: protein- (484 aa) initn: 3324 init1: 3324 opt: 3324 Z-score: 3818.7 bits: 716.4 E(85289): 5.8e-206 Smith-Waterman score: 3324; 99.8% identity (100.0% similar) in 484 aa overlap (180-663:1-484) 150 160 170 180 190 200 pF1KB6 LLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMD :::::::::::::::::::::::::::::: XP_011 MSLMTLSTKTPKDFFTNHTLVLHVARSEMD 10 20 30 210 220 230 240 250 260 pF1KB6 KVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTNFPGLITLTI ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_011 KVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTI 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB6 SLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMK 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB6 AKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDF 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB6 GYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB6 FLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGH 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB6 GEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQ 340 350 360 370 380 390 570 580 590 600 610 620 pF1KB6 LFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTF 400 410 420 430 440 450 630 640 650 660 pF1KB6 INDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP :::::::::::::::::::::::::::::::::: XP_011 INDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP 460 470 480 >>NP_037490 (OMIM: 607934) protein-arginine deiminase ty (663 aa) initn: 762 init1: 762 opt: 2592 Z-score: 2975.5 bits: 560.9 E(85289): 5.3e-159 Smith-Waterman score: 2592; 56.7% identity (81.3% similar) in 669 aa overlap (1-663:1-663) 10 20 30 40 50 60 pF1KB6 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHSPPAKK :: ..... ..:::::::.:. ...:: :..:. .:: ...: :: : .... : NP_037 MAPKRVVQLSLKMPTHAVCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPV--KALLYLTAVEISLC . :.. :::: ....... .:: : ::..::.: . . ...::::.:.::: NP_037 EPIGKARWPLDTDADMVVSVGTASKELKDFKVRVSYFGEQEDQALGRSVLYLTGVDISLE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 ADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQ .: :::::: :. :..:: ::: : :::::::::::: .:. : . ... ::: NP_037 VDTGRTGKVK--RSQGDKKTWRWGPEGYGAILLVNCDRDNHRSAEPDLTHSWLMSLADLQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 DMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYL ::: : :: . : .: .: :::.: :. .:::: : :. : . ::::. :. . NP_037 DMSPMLLSCNGPDKLFDSHKLVLNVPFSDSKRVRVFCARGGNSLSDYKQVLGPQCLSYEV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 MVPGGKHNMDFYVEALAFPDTNFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIM :.... ::::.:.:::..: ::..:..::.: .. :::...: :.: ::.::::: NP_037 ERQPGEQEIKFYVEGLTFPDADFLGLVSLSVSLVDPGT--LPEVTLFTDTVGFRMAPWIM 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 TPNTQPPQEVYACSIFE----NEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEI :::::::.:.:.: ... :: ::.... :..::.:::::::. :: .:.:.:::::. NP_037 TPNTQPPEELYVCRVMDTHGSNEKFLEDMSYLTLKANCKLTICPQVENRNDRWIQDEMEF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 GYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSP :::.::::..:::::::::::::.:: ::..::::::::: : :.:::::::.::: NP_037 GYIEAPHKSFPVVFDSPRNRGLKDFPYKRILGPDFGYVTREIPLPGPSSLDSFGNLDVSP 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB6 PVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDE :::: : ::::::::.:.: .:.. .::: .:...::.::::::::.::::::::::::: NP_037 PVTVGGTEYPLGRILIGSS-FPKSGGRQMARAVRNFLKAQQVQAPVELYSDWLSVGHVDE 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB6 FLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKT ::.:::. :.:::::::::: .: :::::...::.::: :.:.:.. ...:...:... NP_037 FLTFVPTSDQKGFRLLLASPSACLKLFQEKKEEGYGEAAQFDGLKHQAKRSINEMLADRH 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB6 LREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGK :.. : ...::::::..::::::::::::.:::::: ::.: ::::::.::::.:::: NP_037 LQRDNLHAQKCIDWNRNVLKRELGLAESDIVDIPQLFFLKNFY-AEAFFPDMVNMVVLGK 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 HLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPF .::::::.::.::::::::::: ::::::::.: ::.:...:: .::.::::::::::: NP_037 YLGIPKPYGPIINGRCCLEEKVQSLLEPLGLHCIFIDDYLSYHELQGEIHCGTNVRRKPF 600 610 620 630 640 650 660 pF1KB6 SFKWWNMVP :::::::: NP_037 PFKWWNMVP 660 >>XP_011539453 (OMIM: 180300,605347) PREDICTED: protein- (563 aa) initn: 2585 init1: 2585 opt: 2586 Z-score: 2969.7 bits: 559.6 E(85289): 1.1e-158 Smith-Waterman score: 3608; 84.3% identity (84.9% similar) in 663 aa overlap (1-663:1-563) 10 20 30 40 50 60 pF1KB6 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHSPPAKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_011 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCAD :::::::::::::::::::::.:::::::::::::::::::::::::::::.:::::::: XP_011 KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PGGKHNMDFYVEALAFPDTNFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG :::::::::::::::::::::::::: XP_011 HKTLPVVFDSPRNRGLKEFPIKRVMG---------------------------------- 370 380 430 440 450 460 470 480 pF1KB6 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP XP_011 ------------------------------------------------------------ 490 500 510 520 530 540 pF1KB6 APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ------FRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS 390 400 410 420 430 440 550 560 570 580 590 600 pF1KB6 FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK 450 460 470 480 490 500 610 620 630 640 650 660 pF1KB6 PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN 510 520 530 540 550 560 pF1KB6 MVP ::: XP_011 MVP >>XP_011539455 (OMIM: 180300,605347) PREDICTED: protein- (397 aa) initn: 2577 init1: 2577 opt: 2578 Z-score: 2962.8 bits: 557.8 E(85289): 2.7e-158 Smith-Waterman score: 2578; 97.2% identity (98.7% similar) in 394 aa overlap (1-394:1-394) 10 20 30 40 50 60 pF1KB6 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHSPPAKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_011 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCAD :::::::::::::::::::::.:::::::::::::::::::::::::::::.:::::::: XP_011 KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PGGKHNMDFYVEALAFPDTNFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG ::::::::::::::::::::::::: ..: : XP_011 HKTLPVVFDSPRNRGLKEFPIKRVMILSIGPFYRRRN 370 380 390 430 440 450 460 470 480 pF1KB6 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP >>XP_011539456 (OMIM: 180300,605347) PREDICTED: protein- (397 aa) initn: 2577 init1: 2577 opt: 2578 Z-score: 2962.8 bits: 557.8 E(85289): 2.7e-158 Smith-Waterman score: 2578; 97.2% identity (98.7% similar) in 394 aa overlap (1-394:1-394) 10 20 30 40 50 60 pF1KB6 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHSPPAKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_011 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCAD :::::::::::::::::::::.:::::::::::::::::::::::::::::.:::::::: XP_011 KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PGGKHNMDFYVEALAFPDTNFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG ::::::::::::::::::::::::: ..: : XP_011 HKTLPVVFDSPRNRGLKEFPIKRVMILSIGPFYRRRN 370 380 390 430 440 450 460 470 480 pF1KB6 KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP >>XP_011539458 (OMIM: 180300,605347) PREDICTED: protein- (386 aa) initn: 2577 init1: 2577 opt: 2577 Z-score: 2961.8 bits: 557.6 E(85289): 3.1e-158 Smith-Waterman score: 2577; 99.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385) 10 20 30 40 50 60 pF1KB6 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHSPPAKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_011 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCAD :::::::::::::::::::::.:::::::::::::::::::::::::::::.:::::::: XP_011 KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PGGKHNMDFYVEALAFPDTNFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG ::::::::::::::::::::::::: XP_011 HKTLPVVFDSPRNRGLKEFPIKRVMQ 370 380 >>XP_011539457 (OMIM: 180300,605347) PREDICTED: protein- (392 aa) initn: 2577 init1: 2577 opt: 2577 Z-score: 2961.7 bits: 557.6 E(85289): 3.1e-158 Smith-Waterman score: 2577; 99.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385) 10 20 30 40 50 60 pF1KB6 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHSPPAKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_011 MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCAD :::::::::::::::::::::.:::::::::::::::::::::::::::::.:::::::: XP_011 KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PGGKHNMDFYVEALAFPDTNFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG ::::::::::::::::::::::::: XP_011 HKTLPVVFDSPRNRGLKEFPIKRVMEDPRPAL 370 380 390 >>XP_011539459 (OMIM: 180300,605347) PREDICTED: protein- (366 aa) initn: 2547 init1: 2547 opt: 2547 Z-score: 2927.7 bits: 551.2 E(85289): 2.5e-156 Smith-Waterman score: 2547; 100.0% identity (100.0% similar) in 366 aa overlap (298-663:1-366) 270 280 290 300 310 320 pF1KB6 TISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLA :::::::::::::::::::::::::::::: XP_011 MTPNTQPPQEVYACSIFENEDFLKSVTTLA 10 20 30 330 340 350 360 370 380 pF1KB6 MKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGP 40 50 60 70 80 90 390 400 410 420 430 440 pF1KB6 DFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQAL 100 110 120 130 140 150 450 460 470 480 490 500 pF1KB6 QDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNE 160 170 180 190 200 210 510 520 530 540 550 560 pF1KB6 GHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDI 220 230 240 250 260 270 570 580 590 600 610 620 pF1KB6 PQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQC 280 290 300 310 320 330 630 640 650 660 pF1KB6 TFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP :::::::::::::::::::::::::::::::::::: XP_011 TFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP 340 350 360 663 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:11:53 2016 done: Sat Nov 5 14:11:54 2016 Total Scan time: 11.060 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]