Result of FASTA (omim) for
pF1KB6205
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6205, 664 aa
1>>>pF1KB6205 664 - 664 aa - 664 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1788+/-0.000515; mu= 15.9342+/- 0.032
mean_var=108.9894+/-22.003, 0's: 0 Z-trim(109.4): 110 B-trim: 179 in 1/58
Lambda= 0.122852
statistics sampled from 17457 (17567) to 17457 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.206), width: 16
Scan time: 9.670
The best scores are: opt bits E(85289)
NP_060641 (OMIM: 606231) DCC-interacting protein 1 ( 664) 4263 767.5 0
NP_001238833 (OMIM: 606231) DCC-interacting protei ( 670) 4241 763.6 0
XP_016875040 (OMIM: 606231) PREDICTED: DCC-interac ( 651) 4167 750.5 4.5e-216
XP_011536832 (OMIM: 606231) PREDICTED: DCC-interac ( 657) 4145 746.6 6.8e-215
XP_016875041 (OMIM: 606231) PREDICTED: DCC-interac ( 621) 3998 720.5 4.5e-207
NP_001238834 (OMIM: 606231) DCC-interacting protei ( 621) 3998 720.5 4.5e-207
XP_016875042 (OMIM: 606231) PREDICTED: DCC-interac ( 621) 3998 720.5 4.5e-207
XP_011536834 (OMIM: 606231) PREDICTED: DCC-interac ( 627) 3976 716.6 6.8e-206
XP_011536833 (OMIM: 606231) PREDICTED: DCC-interac ( 627) 3976 716.6 6.8e-206
XP_016875043 (OMIM: 606231) PREDICTED: DCC-interac ( 617) 3571 644.8 2.7e-184
XP_006719535 (OMIM: 606231) PREDICTED: DCC-interac ( 623) 3549 640.9 4.1e-183
NP_036228 (OMIM: 604299,616511) DCC-interacting pr ( 709) 2177 397.8 7.2e-110
XP_011531885 (OMIM: 604299,616511) PREDICTED: DCC- ( 692) 2090 382.4 3.1e-105
XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785) 384 80.0 3.6e-14
XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP wit ( 820) 384 80.1 3.7e-14
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 359 75.6 7.7e-13
XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 359 75.6 7.9e-13
XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 331 70.6 2.4e-11
XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 331 70.6 2.4e-11
XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 331 70.6 2.4e-11
XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806) 315 67.8 1.8e-10
XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP wit ( 841) 315 67.8 1.8e-10
XP_005263272 (OMIM: 609746) PREDICTED: rho GTPase- ( 735) 302 65.5 8.1e-10
NP_078881 (OMIM: 609746) rho GTPase-activating pro ( 786) 302 65.5 8.5e-10
XP_016861537 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 291 63.6 3.4e-09
XP_016861535 (OMIM: 607766) PREDICTED: arf-GAP wit ( 848) 291 63.6 3.5e-09
NP_689645 (OMIM: 615936) rho GTPase-activating pro ( 874) 290 63.4 4e-09
XP_016885044 (OMIM: 300127,300486) PREDICTED: olig ( 565) 272 60.1 2.6e-08
XP_005268459 (OMIM: 605370,607785) PREDICTED: rho ( 722) 273 60.3 2.8e-08
NP_001129080 (OMIM: 605370,607785) rho GTPase-acti ( 759) 273 60.4 2.9e-08
NP_055886 (OMIM: 605370,607785) rho GTPase-activat ( 814) 273 60.4 3.1e-08
XP_005262327 (OMIM: 300127,300486) PREDICTED: olig ( 694) 272 60.1 3.1e-08
XP_006724716 (OMIM: 300127,300486) PREDICTED: olig ( 793) 272 60.2 3.4e-08
XP_011529263 (OMIM: 300127,300486) PREDICTED: olig ( 802) 272 60.2 3.4e-08
NP_002538 (OMIM: 300127,300486) oligophrenin-1 [Ho ( 802) 272 60.2 3.4e-08
XP_016872726 (OMIM: 615936) PREDICTED: rho GTPase- ( 820) 247 55.8 7.5e-07
XP_011540918 (OMIM: 615936) PREDICTED: rho GTPase- ( 820) 247 55.8 7.5e-07
XP_011540917 (OMIM: 615936) PREDICTED: rho GTPase- ( 820) 247 55.8 7.5e-07
XP_011535913 (OMIM: 605370,607785) PREDICTED: rho ( 612) 230 52.7 4.9e-06
XP_011535912 (OMIM: 605370,607785) PREDICTED: rho ( 616) 230 52.7 4.9e-06
XP_006714837 (OMIM: 605370,607785) PREDICTED: rho ( 628) 230 52.7 5e-06
XP_016864739 (OMIM: 605370,607785) PREDICTED: rho ( 725) 230 52.7 5.5e-06
XP_005268457 (OMIM: 605370,607785) PREDICTED: rho ( 765) 230 52.7 5.8e-06
XP_005268456 (OMIM: 605370,607785) PREDICTED: rho ( 802) 230 52.8 6e-06
XP_016864738 (OMIM: 605370,607785) PREDICTED: rho ( 811) 230 52.8 6e-06
XP_016864737 (OMIM: 605370,607785) PREDICTED: rho ( 812) 230 52.8 6e-06
XP_005268455 (OMIM: 605370,607785) PREDICTED: rho ( 857) 230 52.8 6.3e-06
XP_016864736 (OMIM: 605370,607785) PREDICTED: rho ( 866) 230 52.8 6.3e-06
XP_011540919 (OMIM: 615936) PREDICTED: rho GTPase- ( 780) 211 49.4 6.1e-05
XP_016864091 (OMIM: 609746) PREDICTED: rho GTPase- ( 694) 210 49.2 6.3e-05
>>NP_060641 (OMIM: 606231) DCC-interacting protein 13-be (664 aa)
initn: 4263 init1: 4263 opt: 4263 Z-score: 4092.0 bits: 767.5 E(85289): 0
Smith-Waterman score: 4263; 100.0% identity (100.0% similar) in 664 aa overlap (1-664:1-664)
10 20 30 40 50 60
pF1KB6 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDLTEVSTLKDLFGLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KDLTEVSTLKDLFGLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 YYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 YFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 KENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 EMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 SFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 SQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 EGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGA
610 620 630 640 650 660
pF1KB6 ESEA
::::
NP_060 ESEA
>>NP_001238833 (OMIM: 606231) DCC-interacting protein 13 (670 aa)
initn: 4251 init1: 3403 opt: 4241 Z-score: 4070.9 bits: 763.6 E(85289): 0
Smith-Waterman score: 4241; 99.1% identity (99.1% similar) in 670 aa overlap (1-664:1-670)
10 20 30 40 50 60
pF1KB6 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 KDLTEVSTLKDLFGLASN------EHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQ
:::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 KDLTEVSTLKDLFGLASNDVCLFLEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 HLSSLQYYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSSLQYYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 SIQVELEAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIQVELEAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVT
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 TTWERLYFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTWERLYFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGII
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 LQAESRKENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAESRKENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB6 QNLKNSEMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNLKNSEMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPF
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB6 GETEDESFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GETEDESFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB6 SHLMVTSQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHLMVTSQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTY
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB6 IFESNSEGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFESNSEGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNP
610 620 630 640 650 660
660
pF1KB6 NEHRGAESEA
::::::::::
NP_001 NEHRGAESEA
670
>>XP_016875040 (OMIM: 606231) PREDICTED: DCC-interacting (651 aa)
initn: 4167 init1: 4167 opt: 4167 Z-score: 4000.2 bits: 750.5 E(85289): 4.5e-216
Smith-Waterman score: 4167; 99.8% identity (100.0% similar) in 649 aa overlap (16-664:3-651)
10 20 30 40 50 60
pF1KB6 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
.::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTTPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
10 20 30 40
70 80 90 100 110 120
pF1KB6 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 KDLTEVSTLKDLFGLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLTEVSTLKDLFGLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 YYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVEL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 EAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 YFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESR
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 KENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNS
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB6 EMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB6 SFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVT
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB6 SQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNS
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB6 EGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGA
590 600 610 620 630 640
pF1KB6 ESEA
::::
XP_016 ESEA
650
>>XP_011536832 (OMIM: 606231) PREDICTED: DCC-interacting (657 aa)
initn: 4153 init1: 3403 opt: 4145 Z-score: 3979.0 bits: 746.6 E(85289): 6.8e-215
Smith-Waterman score: 4145; 98.9% identity (99.1% similar) in 655 aa overlap (16-664:3-657)
10 20 30 40 50 60
pF1KB6 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
.::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTTPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
10 20 30 40
70 80 90 100 110 120
pF1KB6 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
50 60 70 80 90 100
130 140 150 160 170
pF1KB6 KDLTEVSTLKDLFGLASN------EHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQ
:::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_011 KDLTEVSTLKDLFGLASNDVCLFLEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQ
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 HLSSLQYYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLSSLQYYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 SIQVELEAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIQVELEAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVT
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB6 TTWERLYFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTWERLYFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGII
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB6 LQAESRKENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQAESRKENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPS
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB6 QNLKNSEMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNLKNSEMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPF
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB6 GETEDESFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GETEDESFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTE
470 480 490 500 510 520
540 550 560 570 580 590
pF1KB6 SHLMVTSQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLMVTSQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTY
530 540 550 560 570 580
600 610 620 630 640 650
pF1KB6 IFESNSEGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFESNSEGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNP
590 600 610 620 630 640
660
pF1KB6 NEHRGAESEA
::::::::::
XP_011 NEHRGAESEA
650
>>XP_016875041 (OMIM: 606231) PREDICTED: DCC-interacting (621 aa)
initn: 3998 init1: 3998 opt: 3998 Z-score: 3838.6 bits: 720.5 E(85289): 4.5e-207
Smith-Waterman score: 3998; 100.0% identity (100.0% similar) in 621 aa overlap (44-664:1-621)
20 30 40 50 60 70
pF1KB6 QDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQLSKQLLAYEKQNF
::::::::::::::::::::::::::::::
XP_016 MQRVYGAQNEMCLATQQLSKQLLAYEKQNF
10 20 30
80 90 100 110 120 130
pF1KB6 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 GLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNALQYRKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNALQYRKQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB6 MAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKMRVSQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKMRVSQQE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB6 LLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGGNLMCQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGGNLMCQP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB6 RGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWICAINNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWICAINNI
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB6 SRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENENDKIVPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENENDKIVPKA
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB6 TASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAEDSLLQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAEDSLLQQM
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB6 FIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLIDPQTQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLIDPQTQV
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB6 SRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICYAINLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICYAINLGK
520 530 540 550 560 570
620 630 640 650 660
pF1KB6 EIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
580 590 600 610 620
>>NP_001238834 (OMIM: 606231) DCC-interacting protein 13 (621 aa)
initn: 3998 init1: 3998 opt: 3998 Z-score: 3838.6 bits: 720.5 E(85289): 4.5e-207
Smith-Waterman score: 3998; 100.0% identity (100.0% similar) in 621 aa overlap (44-664:1-621)
20 30 40 50 60 70
pF1KB6 QDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQLSKQLLAYEKQNF
::::::::::::::::::::::::::::::
NP_001 MQRVYGAQNEMCLATQQLSKQLLAYEKQNF
10 20 30
80 90 100 110 120 130
pF1KB6 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 GLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNALQYRKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNALQYRKQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB6 MAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKMRVSQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKMRVSQQE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB6 LLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGGNLMCQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGGNLMCQP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB6 RGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWICAINNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWICAINNI
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB6 SRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENENDKIVPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENENDKIVPKA
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB6 TASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAEDSLLQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAEDSLLQQM
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB6 FIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLIDPQTQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLIDPQTQV
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB6 SRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICYAINLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICYAINLGK
520 530 540 550 560 570
620 630 640 650 660
pF1KB6 EIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
580 590 600 610 620
>>XP_016875042 (OMIM: 606231) PREDICTED: DCC-interacting (621 aa)
initn: 3998 init1: 3998 opt: 3998 Z-score: 3838.6 bits: 720.5 E(85289): 4.5e-207
Smith-Waterman score: 3998; 100.0% identity (100.0% similar) in 621 aa overlap (44-664:1-621)
20 30 40 50 60 70
pF1KB6 QDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQLSKQLLAYEKQNF
::::::::::::::::::::::::::::::
XP_016 MQRVYGAQNEMCLATQQLSKQLLAYEKQNF
10 20 30
80 90 100 110 120 130
pF1KB6 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 GLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNALQYRKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNALQYRKQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB6 MAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKMRVSQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKMRVSQQE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB6 LLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGGNLMCQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGGNLMCQP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB6 RGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWICAINNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWICAINNI
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB6 SRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENENDKIVPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENENDKIVPKA
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB6 TASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAEDSLLQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAEDSLLQQM
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB6 FIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLIDPQTQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLIDPQTQV
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB6 SRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICYAINLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICYAINLGK
520 530 540 550 560 570
620 630 640 650 660
pF1KB6 EIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
580 590 600 610 620
>>XP_011536834 (OMIM: 606231) PREDICTED: DCC-interacting (627 aa)
initn: 3986 init1: 3403 opt: 3976 Z-score: 3817.4 bits: 716.6 E(85289): 6.8e-206
Smith-Waterman score: 3976; 99.0% identity (99.0% similar) in 627 aa overlap (44-664:1-627)
20 30 40 50 60 70
pF1KB6 QDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQLSKQLLAYEKQNF
::::::::::::::::::::::::::::::
XP_011 MQRVYGAQNEMCLATQQLSKQLLAYEKQNF
10 20 30
80 90 100 110 120 130
pF1KB6 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
40 50 60 70 80 90
140 150 160 170 180
pF1KB6 GLASN------EHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNA
::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLASNDVCLFLEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNA
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 LQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 RVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 NLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 CAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENEND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENEND
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB6 KIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAED
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB6 SLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLI
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB6 DPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICY
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB6 AINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
580 590 600 610 620
>>XP_011536833 (OMIM: 606231) PREDICTED: DCC-interacting (627 aa)
initn: 3986 init1: 3403 opt: 3976 Z-score: 3817.4 bits: 716.6 E(85289): 6.8e-206
Smith-Waterman score: 3976; 99.0% identity (99.0% similar) in 627 aa overlap (44-664:1-627)
20 30 40 50 60 70
pF1KB6 QDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQLSKQLLAYEKQNF
::::::::::::::::::::::::::::::
XP_011 MQRVYGAQNEMCLATQQLSKQLLAYEKQNF
10 20 30
80 90 100 110 120 130
pF1KB6 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFREKDLTEVSTLKDLF
40 50 60 70 80 90
140 150 160 170 180
pF1KB6 GLASN------EHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNA
::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLASNDVCLFLEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQYYCALNA
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 LQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVELEAEAEKM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 RVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERLYFFTQGG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 NLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESRKENEEWI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 CAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENEND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENEND
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB6 KIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAED
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB6 SLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQSLRLI
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB6 DPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICY
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB6 AINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGAESEA
580 590 600 610 620
>>XP_016875043 (OMIM: 606231) PREDICTED: DCC-interacting (617 aa)
initn: 3571 init1: 3571 opt: 3571 Z-score: 3429.6 bits: 644.8 E(85289): 2.7e-184
Smith-Waterman score: 3868; 92.9% identity (92.9% similar) in 664 aa overlap (1-664:1-617)
10 20 30 40 50 60
pF1KB6 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDLTEVSTLKDLFGLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLTEVSTLKDLFGLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 YYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 YFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 KENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 EMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMENENDKIVPKATASLPEAEELIAPGTPIQFDIVLPATEFLDQNRGSRRTNPFGETEDE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 SFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFRMTESHLMVT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 SQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNS
:::::::::::::::::
XP_016 SQSLRLIDPQTQVSRAN-------------------------------------------
550
610 620 630 640 650 660
pF1KB6 EGEKICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----ICYAINLGKEIIEVQKDPEALAQLMLSIPLTNDGKYVLLNDQPDDDDGNPNEHRGA
560 570 580 590 600 610
pF1KB6 ESEA
::::
XP_016 ESEA
664 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:49:07 2016 done: Sat Nov 5 13:49:08 2016
Total Scan time: 9.670 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]