FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6239, 751 aa 1>>>pF1KB6239 751 - 751 aa - 751 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6494+/-0.000388; mu= 10.6184+/- 0.024 mean_var=174.5193+/-34.502, 0's: 0 Z-trim(119.0): 172 B-trim: 634 in 1/54 Lambda= 0.097085 statistics sampled from 32306 (32479) to 32306 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.381), width: 16 Scan time: 11.010 The best scores are: opt bits E(85289) XP_011514186 (OMIM: 277590,601573) PREDICTED: hist ( 751) 5251 748.2 2.8e-215 NP_004447 (OMIM: 277590,601573) histone-lysine N-m ( 751) 5251 748.2 2.8e-215 XP_011514185 (OMIM: 277590,601573) PREDICTED: hist ( 759) 5251 748.2 2.8e-215 XP_016867306 (OMIM: 277590,601573) PREDICTED: hist ( 759) 5251 748.2 2.8e-215 NP_001190176 (OMIM: 277590,601573) histone-lysine ( 746) 5184 738.8 1.8e-212 XP_005250019 (OMIM: 277590,601573) PREDICTED: hist ( 754) 5184 738.8 1.9e-212 XP_011514193 (OMIM: 277590,601573) PREDICTED: hist ( 718) 4724 674.4 4.5e-193 XP_011514191 (OMIM: 277590,601573) PREDICTED: hist ( 729) 4712 672.7 1.4e-192 XP_011514188 (OMIM: 277590,601573) PREDICTED: hist ( 743) 4712 672.7 1.5e-192 XP_011514190 (OMIM: 277590,601573) PREDICTED: hist ( 742) 4710 672.4 1.8e-192 XP_011514189 (OMIM: 277590,601573) PREDICTED: hist ( 742) 4710 672.4 1.8e-192 XP_011514187 (OMIM: 277590,601573) PREDICTED: hist ( 750) 4710 672.5 1.8e-192 XP_016867307 (OMIM: 277590,601573) PREDICTED: hist ( 738) 4645 663.3 9.8e-190 NP_001190177 (OMIM: 277590,601573) histone-lysine ( 737) 4643 663.1 1.2e-189 XP_005250020 (OMIM: 277590,601573) PREDICTED: hist ( 745) 4643 663.1 1.2e-189 XP_011514200 (OMIM: 277590,601573) PREDICTED: hist ( 642) 4538 648.3 2.9e-185 XP_011514199 (OMIM: 277590,601573) PREDICTED: hist ( 642) 4538 648.3 2.9e-185 XP_016867310 (OMIM: 277590,601573) PREDICTED: hist ( 637) 4471 638.9 1.9e-182 XP_011514196 (OMIM: 277590,601573) PREDICTED: hist ( 712) 4464 638.0 4.1e-182 XP_011514192 (OMIM: 277590,601573) PREDICTED: hist ( 720) 4464 638.0 4.1e-182 XP_016867309 (OMIM: 277590,601573) PREDICTED: hist ( 703) 4448 635.7 1.9e-181 XP_011514197 (OMIM: 277590,601573) PREDICTED: hist ( 711) 4448 635.7 1.9e-181 NP_694543 (OMIM: 277590,601573) histone-lysine N-m ( 707) 4397 628.6 2.7e-179 XP_011514195 (OMIM: 277590,601573) PREDICTED: hist ( 715) 4397 628.6 2.7e-179 XP_011514194 (OMIM: 277590,601573) PREDICTED: hist ( 717) 3569 512.6 2.2e-144 XP_016867308 (OMIM: 277590,601573) PREDICTED: hist ( 712) 3472 499.0 2.7e-140 XP_011514201 (OMIM: 277590,601573) PREDICTED: hist ( 511) 3434 493.6 8.5e-139 NP_001190178 (OMIM: 277590,601573) histone-lysine ( 695) 2931 423.2 1.7e-117 XP_005250021 (OMIM: 277590,601573) PREDICTED: hist ( 703) 2931 423.3 1.7e-117 XP_011514203 (OMIM: 277590,601573) PREDICTED: hist ( 432) 2821 407.7 5.3e-113 XP_011514198 (OMIM: 277590,601573) PREDICTED: hist ( 673) 2715 393.0 2.2e-108 NP_001982 (OMIM: 601674) histone-lysine N-methyltr ( 747) 2624 380.3 1.6e-104 NP_001308008 (OMIM: 601674) histone-lysine N-methy ( 753) 2624 380.3 1.6e-104 NP_001308010 (OMIM: 601674) histone-lysine N-methy ( 738) 2414 350.9 1.1e-95 XP_011522819 (OMIM: 601674) PREDICTED: histone-lys ( 744) 2414 350.9 1.1e-95 XP_016879839 (OMIM: 601674) PREDICTED: histone-lys ( 668) 2409 350.1 1.7e-95 NP_001308011 (OMIM: 601674) histone-lysine N-methy ( 707) 2253 328.3 6.8e-89 XP_005257202 (OMIM: 601674) PREDICTED: histone-lys ( 713) 2253 328.3 6.8e-89 XP_016879840 (OMIM: 601674) PREDICTED: histone-lys ( 637) 2252 328.1 6.9e-89 XP_016879841 (OMIM: 601674) PREDICTED: histone-lys ( 410) 2073 302.9 1.8e-81 NP_003164 (OMIM: 300254) histone-lysine N-methyltr ( 412) 334 59.3 3.7e-08 NP_001269095 (OMIM: 300254) histone-lysine N-methy ( 423) 334 59.3 3.8e-08 XP_011508072 (OMIM: 607999) PREDICTED: histone-lys (1244) 340 60.6 4.7e-08 XP_016857277 (OMIM: 607999) PREDICTED: histone-lys (1244) 340 60.6 4.7e-08 XP_016864076 (OMIM: 194190,602952) PREDICTED: hist ( 584) 332 59.2 5.8e-08 XP_011511862 (OMIM: 194190,602952) PREDICTED: hist ( 584) 332 59.2 5.8e-08 XP_016864077 (OMIM: 194190,602952) PREDICTED: hist ( 584) 332 59.2 5.8e-08 NP_758859 (OMIM: 117550,130650,606681) histone-lys (2427) 341 60.9 7e-08 NP_078946 (OMIM: 606503) histone-lysine N-methyltr ( 350) 326 58.1 7.1e-08 XP_006717566 (OMIM: 606503) PREDICTED: histone-lys ( 350) 326 58.1 7.1e-08 >>XP_011514186 (OMIM: 277590,601573) PREDICTED: histone- (751 aa) initn: 5251 init1: 5251 opt: 5251 Z-score: 3986.0 bits: 748.2 E(85289): 2.8e-215 Smith-Waterman score: 5251; 100.0% identity (100.0% similar) in 751 aa overlap (1-751:1-751) 10 20 30 40 50 60 pF1KB6 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA 670 680 690 700 710 720 730 740 750 pF1KB6 IQTGEELFFDYRYSQADALKYVGIEREMEIP ::::::::::::::::::::::::::::::: XP_011 IQTGEELFFDYRYSQADALKYVGIEREMEIP 730 740 750 >>NP_004447 (OMIM: 277590,601573) histone-lysine N-methy (751 aa) initn: 5251 init1: 5251 opt: 5251 Z-score: 3986.0 bits: 748.2 E(85289): 2.8e-215 Smith-Waterman score: 5251; 100.0% identity (100.0% similar) in 751 aa overlap (1-751:1-751) 10 20 30 40 50 60 pF1KB6 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA 670 680 690 700 710 720 730 740 750 pF1KB6 IQTGEELFFDYRYSQADALKYVGIEREMEIP ::::::::::::::::::::::::::::::: NP_004 IQTGEELFFDYRYSQADALKYVGIEREMEIP 730 740 750 >>XP_011514185 (OMIM: 277590,601573) PREDICTED: histone- (759 aa) initn: 5251 init1: 5251 opt: 5251 Z-score: 3985.9 bits: 748.2 E(85289): 2.8e-215 Smith-Waterman score: 5251; 100.0% identity (100.0% similar) in 751 aa overlap (1-751:9-759) 10 20 30 40 50 pF1KB6 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILER :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIYFIRIIMGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 WSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 ELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 DKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 DCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 KRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 SEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVY 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 EFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPR 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 QPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 CGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIIS 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB6 QDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR 670 680 690 700 710 720 720 730 740 750 pF1KB6 IGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP ::::::::::::::::::::::::::::::::::::::: XP_011 IGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP 730 740 750 >>XP_016867306 (OMIM: 277590,601573) PREDICTED: histone- (759 aa) initn: 5251 init1: 5251 opt: 5251 Z-score: 3985.9 bits: 748.2 E(85289): 2.8e-215 Smith-Waterman score: 5251; 100.0% identity (100.0% similar) in 751 aa overlap (1-751:9-759) 10 20 30 40 50 pF1KB6 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILER :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIYFIRIIMGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 WSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 ELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 DKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 DCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 KRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 SEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVY 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 EFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPR 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 QPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 CGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIIS 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB6 QDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR 670 680 690 700 710 720 720 730 740 750 pF1KB6 IGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP ::::::::::::::::::::::::::::::::::::::: XP_016 IGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP 730 740 750 >>NP_001190176 (OMIM: 277590,601573) histone-lysine N-me (746 aa) initn: 3178 init1: 3178 opt: 5184 Z-score: 3935.3 bits: 738.8 E(85289): 1.8e-212 Smith-Waterman score: 5184; 99.2% identity (99.2% similar) in 751 aa overlap (1-751:1-746) 10 20 30 40 50 60 pF1KB6 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLH--- 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 --PFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB6 SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB6 KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA 660 670 680 690 700 710 730 740 750 pF1KB6 IQTGEELFFDYRYSQADALKYVGIEREMEIP ::::::::::::::::::::::::::::::: NP_001 IQTGEELFFDYRYSQADALKYVGIEREMEIP 720 730 740 >>XP_005250019 (OMIM: 277590,601573) PREDICTED: histone- (754 aa) initn: 3178 init1: 3178 opt: 5184 Z-score: 3935.3 bits: 738.8 E(85289): 1.9e-212 Smith-Waterman score: 5184; 99.2% identity (99.2% similar) in 751 aa overlap (1-751:9-754) 10 20 30 40 50 pF1KB6 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILER :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MIYFIRIIMGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 WSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 ELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 DKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 DCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPP ::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DCFLH-----PFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPP 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 KRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSS 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB6 SEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVY 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB6 EFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB6 QPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLT 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 CGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIIS 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB6 QDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR 660 670 680 690 700 710 720 730 740 750 pF1KB6 IGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP ::::::::::::::::::::::::::::::::::::::: XP_005 IGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP 720 730 740 750 >>XP_011514193 (OMIM: 277590,601573) PREDICTED: histone- (718 aa) initn: 4711 init1: 4711 opt: 4724 Z-score: 3587.3 bits: 674.4 E(85289): 4.5e-193 Smith-Waterman score: 4724; 99.6% identity (99.7% similar) in 676 aa overlap (76-751:44-718) 50 60 70 80 90 100 pF1KB6 RQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVA : :::. ::::::::::::::::::::::: XP_011 ASDTRWDSEGSGAPAAAAAARGGDAREQRESARGTK-CSVTSDLDFPTQVIPLKTLNAVA 20 30 40 50 60 70 110 120 130 140 150 160 pF1KB6 SVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGF 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB6 INDEIFVELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INDEIFVELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFE 140 150 160 170 180 190 230 240 250 260 270 280 pF1KB6 AISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLF 200 210 220 230 240 250 290 300 310 320 330 340 pF1KB6 CRRCFKYDCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRRCFKYDCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTA 260 270 280 290 300 310 350 360 370 380 390 400 pF1KB6 ERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEK 320 330 340 350 360 370 410 420 430 440 450 460 pF1KB6 KDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGT 380 390 400 410 420 430 470 480 490 500 510 520 pF1KB6 KTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNY 440 450 460 470 480 490 530 540 550 560 570 580 pF1KB6 QPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVREC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVREC 500 510 520 530 540 550 590 600 610 620 630 640 pF1KB6 DPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISE 560 570 580 590 600 610 650 660 670 680 690 700 pF1KB6 YCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVM 620 630 640 650 660 670 710 720 730 740 750 pF1KB6 MVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP :::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP 680 690 700 710 >>XP_011514191 (OMIM: 277590,601573) PREDICTED: histone- (729 aa) initn: 4712 init1: 4712 opt: 4712 Z-score: 3578.2 bits: 672.7 E(85289): 1.4e-192 Smith-Waterman score: 4712; 99.9% identity (100.0% similar) in 670 aa overlap (82-751:60-729) 60 70 80 90 100 110 pF1KB6 RTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMY .::::::::::::::::::::::::::::: XP_011 VYSYNYYFWLDFPLQLPVVQPHSRLLYQLVDCSVTSDLDFPTQVIPLKTLNAVASVPIMY 30 40 50 60 70 80 120 130 140 150 160 170 pF1KB6 SWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIF 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB6 VELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMF 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB6 PDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFK 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB6 YDCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTP 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 PKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSS 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB6 SSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQV 390 400 410 420 430 440 480 490 500 510 520 530 pF1KB6 YEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHP 450 460 470 480 490 500 540 550 560 570 580 590 pF1KB6 RQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCL 510 520 530 540 550 560 600 610 620 630 640 650 pF1KB6 TCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEII 570 580 590 600 610 620 660 670 680 690 700 710 pF1KB6 SQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDH 630 640 650 660 670 680 720 730 740 750 pF1KB6 RIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP :::::::::::::::::::::::::::::::::::::::: XP_011 RIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP 690 700 710 720 >>XP_011514188 (OMIM: 277590,601573) PREDICTED: histone- (743 aa) initn: 4712 init1: 4712 opt: 4712 Z-score: 3578.1 bits: 672.7 E(85289): 1.5e-192 Smith-Waterman score: 4712; 99.9% identity (100.0% similar) in 670 aa overlap (82-751:74-743) 60 70 80 90 100 110 pF1KB6 RTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMY .::::::::::::::::::::::::::::: XP_011 VYSYNYYFWLDFPLQLPVVQPHSRLLYQLVDCSVTSDLDFPTQVIPLKTLNAVASVPIMY 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 SWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIF 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 VELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMF 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 PDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFK 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB6 YDCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTP 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB6 PKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSS 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB6 SSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQV 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB6 YEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHP 470 480 490 500 510 520 540 550 560 570 580 590 pF1KB6 RQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCL 530 540 550 560 570 580 600 610 620 630 640 650 pF1KB6 TCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEII 590 600 610 620 630 640 660 670 680 690 700 710 pF1KB6 SQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDH 650 660 670 680 690 700 720 730 740 750 pF1KB6 RIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP :::::::::::::::::::::::::::::::::::::::: XP_011 RIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP 710 720 730 740 >>XP_011514190 (OMIM: 277590,601573) PREDICTED: histone- (742 aa) initn: 4710 init1: 4710 opt: 4710 Z-score: 3576.5 bits: 672.4 E(85289): 1.8e-192 Smith-Waterman score: 5170; 98.8% identity (98.8% similar) in 751 aa overlap (1-751:1-742) 10 20 30 40 50 60 pF1KB6 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF ::::::::::::: :::::::::::::::::::::::::::::::::::::: XP_011 KQRRIQPVHILTS---------CSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB6 SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB6 KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA 660 670 680 690 700 710 730 740 750 pF1KB6 IQTGEELFFDYRYSQADALKYVGIEREMEIP ::::::::::::::::::::::::::::::: XP_011 IQTGEELFFDYRYSQADALKYVGIEREMEIP 720 730 740 751 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 01:53:57 2016 done: Mon Nov 7 01:53:59 2016 Total Scan time: 11.010 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]