FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6240, 677 aa 1>>>pF1KB6240 677 - 677 aa - 677 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8138+/-0.00113; mu= -0.5518+/- 0.068 mean_var=234.7567+/-47.342, 0's: 0 Z-trim(111.0): 117 B-trim: 226 in 2/50 Lambda= 0.083708 statistics sampled from 11906 (12023) to 11906 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.369), width: 16 Scan time: 3.560 The best scores are: opt bits E(32554) CCDS2914.1 FOXP1 gene_id:27086|Hs108|chr3 ( 677) 4486 555.2 1.1e-157 CCDS58839.1 FOXP1 gene_id:27086|Hs108|chr3 ( 676) 4469 553.1 4.7e-157 CCDS58837.1 FOXP1 gene_id:27086|Hs108|chr3 ( 679) 4089 507.2 3.1e-143 CCDS74963.1 FOXP1 gene_id:27086|Hs108|chr3 ( 577) 3837 476.8 3.9e-134 CCDS74964.1 FOXP1 gene_id:27086|Hs108|chr3 ( 693) 3527 439.4 8.4e-123 CCDS58838.1 FOXP1 gene_id:27086|Hs108|chr3 ( 601) 3443 429.2 8.4e-120 CCDS55154.1 FOXP2 gene_id:93986|Hs108|chr7 ( 732) 2463 310.9 4.2e-84 CCDS43635.1 FOXP2 gene_id:93986|Hs108|chr7 ( 740) 2461 310.6 5e-84 CCDS5760.1 FOXP2 gene_id:93986|Hs108|chr7 ( 715) 2459 310.4 5.8e-84 CCDS34447.1 FOXP4 gene_id:116113|Hs108|chr6 ( 680) 2366 299.1 1.3e-80 CCDS34448.1 FOXP4 gene_id:116113|Hs108|chr6 ( 678) 2350 297.2 5.1e-80 CCDS4856.1 FOXP4 gene_id:116113|Hs108|chr6 ( 667) 1205 158.9 2.1e-38 CCDS5761.2 FOXP2 gene_id:93986|Hs108|chr7 ( 432) 1124 149.0 1.3e-35 CCDS48109.1 FOXP3 gene_id:50943|Hs108|chrX ( 396) 535 77.9 3.1e-14 CCDS14323.1 FOXP3 gene_id:50943|Hs108|chrX ( 431) 535 77.9 3.3e-14 >>CCDS2914.1 FOXP1 gene_id:27086|Hs108|chr3 (677 aa) initn: 4486 init1: 4486 opt: 4486 Z-score: 2944.2 bits: 555.2 E(32554): 1.1e-157 Smith-Waterman score: 4486; 100.0% identity (100.0% similar) in 677 aa overlap (1-677:1-677) 10 20 30 40 50 60 pF1KB6 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 LSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 AEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 PLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 RLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 RLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 PSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 PSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 SPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 SPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 FQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 FQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 AIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 AIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPD 610 620 630 640 650 660 670 pF1KB6 FDHDRDYEDEPVNEDME ::::::::::::::::: CCDS29 FDHDRDYEDEPVNEDME 670 >>CCDS58839.1 FOXP1 gene_id:27086|Hs108|chr3 (676 aa) initn: 2959 init1: 2959 opt: 4469 Z-score: 2933.2 bits: 553.1 E(32554): 4.7e-157 Smith-Waterman score: 4469; 99.9% identity (99.9% similar) in 677 aa overlap (1-677:1-676) 10 20 30 40 50 60 pF1KB6 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 RLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 PSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILE ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS58 PSVITTTSMHTVGPIRRRYSDKYNVPISS-DIAQNQEFYKNAEVRPPFTYASLIRQAILE 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 SPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 FQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLAS 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB6 AIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPD 600 610 620 630 640 650 670 pF1KB6 FDHDRDYEDEPVNEDME ::::::::::::::::: CCDS58 FDHDRDYEDEPVNEDME 660 670 >>CCDS58837.1 FOXP1 gene_id:27086|Hs108|chr3 (679 aa) initn: 4089 init1: 4089 opt: 4089 Z-score: 2685.1 bits: 507.2 E(32554): 3.1e-143 Smith-Waterman score: 4089; 100.0% identity (100.0% similar) in 617 aa overlap (61-677:63-679) 40 50 60 70 80 90 pF1KB6 GLREGRSNGETPAVDIGAADLAHAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQ :::::::::::::::::::::::::::::: CCDS58 QKQPEPIYSKKTEIQRQTVRAPFAKLFIFSALQVARQLLLQQQQQQQVSGLKSPKRNDKQ 40 50 60 70 80 90 100 110 120 130 140 150 pF1KB6 PALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQ 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB6 QEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPG 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB6 QPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLI 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB6 MNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSE 280 290 300 310 320 330 340 350 360 370 380 390 pF1KB6 HALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVT 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB6 LSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSA 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB6 DIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWK 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB6 NAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLN 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB6 AALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAV 580 590 600 610 620 630 640 650 660 670 pF1KB6 HPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME ::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME 640 650 660 670 >>CCDS74963.1 FOXP1 gene_id:27086|Hs108|chr3 (577 aa) initn: 3837 init1: 3837 opt: 3837 Z-score: 2521.7 bits: 476.8 E(32554): 3.9e-134 Smith-Waterman score: 3837; 100.0% identity (100.0% similar) in 577 aa overlap (101-677:1-577) 80 90 100 110 120 130 pF1KB6 QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLL :::::::::::::::::::::::::::::: CCDS74 MMTPQVITPQQMQQILQQQVLSPQQLQVLL 10 20 30 140 150 160 170 180 190 pF1KB6 QQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQ 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKW 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 PGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLH 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 VKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 VKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNE 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 IYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 IYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKIS 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 GNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 GNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 EHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 EHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDE 520 530 540 550 560 570 pF1KB6 PVNEDME ::::::: CCDS74 PVNEDME >>CCDS74964.1 FOXP1 gene_id:27086|Hs108|chr3 (693 aa) initn: 4512 init1: 3520 opt: 3527 Z-score: 2318.2 bits: 439.4 E(32554): 8.4e-123 Smith-Waterman score: 4334; 95.2% identity (96.7% similar) in 693 aa overlap (1-677:1-693) 10 20 30 40 50 60 pF1KB6 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 AEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 RLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 PSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 SPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE ::::::::::::::::::::::::::::::.:.: ::::::::.:::. :. ::::. : CCDS74 SPEKQLTLNEIYNWFTRMFAYFRRNAATWKGAIRTNLSLHKCFIRVEDEFGSFWTVDDEE 490 500 510 520 530 540 550 560 570 580 pF1KB6 F------QKRRPQK----------ISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPL : :. ::.: .. ::::::::::::::::::::::::::::::::: CCDS74 FKRGRHIQRGRPRKYCPDENFDELVAHNPSLIKNMQSSHAYCTPLNAALQASMAENSIPL 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB6 YTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 YTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEE 610 620 630 640 650 660 650 660 670 pF1KB6 AEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME ::::::::::::::::::::::::::::::::: CCDS74 AEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME 670 680 690 >>CCDS58838.1 FOXP1 gene_id:27086|Hs108|chr3 (601 aa) initn: 3420 init1: 3420 opt: 3443 Z-score: 2264.3 bits: 429.2 E(32554): 8.4e-120 Smith-Waterman score: 3832; 88.8% identity (88.8% similar) in 677 aa overlap (1-677:1-601) 10 20 30 40 50 60 pF1KB6 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV :::::::::::::::::::::::::::::::::: CCDS58 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQ-------------------------- 70 80 90 130 140 150 160 170 180 pF1KB6 LSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA :::::::::: CCDS58 --------------------------------------------------QQQVATQQLA 100 190 200 210 220 230 240 pF1KB6 FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHT 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB6 AEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSH 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB6 PLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKE 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB6 RLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQG 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB6 PSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILE 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB6 SPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVE 410 420 430 440 450 460 550 560 570 580 590 600 pF1KB6 FQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLAS 470 480 490 500 510 520 610 620 630 640 650 660 pF1KB6 AIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPD 530 540 550 560 570 580 670 pF1KB6 FDHDRDYEDEPVNEDME ::::::::::::::::: CCDS58 FDHDRDYEDEPVNEDME 590 600 >>CCDS55154.1 FOXP2 gene_id:93986|Hs108|chr7 (732 aa) initn: 2020 init1: 1010 opt: 2463 Z-score: 1623.4 bits: 310.9 E(32554): 4.2e-84 Smith-Waterman score: 2813; 63.3% identity (80.1% similar) in 713 aa overlap (31-677:30-732) 10 20 30 40 50 60 pF1KB6 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ : :.:::.:.: . ......: : :::: CCDS55 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSS-EVSTVELLHLQQQQ-- 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV :::.::::::: ::.::::::: .::: :::::::::::::::::::::::::::: CCDS55 ALQAARQLLLQ----QQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 60 70 80 90 100 110 130 140 150 160 pF1KB6 LSPQQLQVLLQQQQALMLQQ-----------------QQLQEFYKKQQEQLQLQLLQQQ- :::::::.:::::::.:::: ::::::::::::::.::::::: CCDS55 LSPQQLQALLQQQQAVMLQQDFLDSGLENFRAALEKNQQLQEFYKKQQEQLHLQLLQQQQ 120 130 140 150 160 170 170 pF1KB6 ------------------------------------HAGKQPKEQQQ-------VATQQL : ::: ::::: .:.::: CCDS55 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 180 190 200 210 220 230 180 190 200 210 220 230 pF1KB6 AFQQQLLQMQQLQQQ-HLLSLQRQGLLTIQPGQPALPLQPLAQ-GMIPTELQQLWKEVTS .:::::::::::::: ::::::::::..: ::: :::.: : : :. :.:.::::::::. CCDS55 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB6 AHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNP---HASTNGQLSVHTPKRESLSHE .:. :.. : .:..:::::. ::.. :.:: : :. .::: :: . .:.: ::: CCDS55 VHSMEDN-GIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHE 300 310 320 330 340 350 300 310 320 330 340 350 pF1KB6 EHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQ : :: :::::::::::::..:::: .::::::.:::::::::::::::::::::::.: CCDS55 ETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQ 360 370 380 390 400 410 360 370 380 390 400 410 pF1KB6 LAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPL :.:..:::::::::::.. .::: .:.:::::::::.::. :.::::::.::::::::. CCDS55 LSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPV 420 430 440 450 460 470 420 430 440 450 460 470 pF1KB6 TPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLI ::.:::::::: .:. .:: ::::.:::::.:.:: .:: : ::::::.::::::::.:: CCDS55 TPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSS-EIAPNYEFYKNADVRPPFTYATLI 480 490 500 510 520 530 480 490 500 510 520 530 pF1KB6 RQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVW ::::.:: ..::::::::.:::: :::::::::::::::::::::::::::::::::::: CCDS55 RQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVW 540 550 560 570 580 590 540 550 560 570 580 590 pF1KB6 TVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPT ::::::.:::: :::.:.:.:.::. .: .: . :::.:::..::.:.:: .. .. : . CCDS55 TVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNA 600 610 620 630 640 650 600 610 620 630 640 650 pF1KB6 LGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTT ..: .:..:.:::...: .:: ..:::: ::. .: .::::::. :. . :.::::: CCDS55 SSGLLQAVHEDLNGSLDHIDSN-GNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTT 660 670 680 690 700 660 670 pF1KB6 ANHSPDFDHDRDYEDEPVNEDME :::::... ::. :.::..::.: CCDS55 ANHSPELEDDREIEEEPLSEDLE 710 720 730 >>CCDS43635.1 FOXP2 gene_id:93986|Hs108|chr7 (740 aa) initn: 1792 init1: 1010 opt: 2461 Z-score: 1622.0 bits: 310.6 E(32554): 5e-84 Smith-Waterman score: 2783; 62.6% identity (79.2% similar) in 717 aa overlap (35-677:34-740) 10 20 30 40 50 60 pF1KB6 SGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQALQV :::.:.: . ......: : ::: ::::. CCDS43 ESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSS-EVSTVELLHLQQQ--QALQA 10 20 30 40 50 60 70 80 90 pF1KB6 ARQLLLQQQQQQQVSGLKSPKRNDKQPALQ-------------------------VPVSV :::::: :::.::::::: .::: :: ::::: CCDS43 ARQLLL----QQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSV 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 AMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLL ::::::::::::::::::::::::::::.:::::::.::::::::::::::::::.:::: CCDS43 AMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLL 120 130 140 150 160 170 160 170 pF1KB6 QQQ-------------------------------------HAGKQPKEQQQ-------VA ::: : ::: ::::: .: CCDS43 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA 180 190 200 210 220 230 180 190 200 210 220 230 pF1KB6 TQQLAFQQQLLQMQQLQQQ-HLLSLQRQGLLTIQPGQPALPLQPLAQ-GMIPTELQQLWK .:::.:::::::::::::: ::::::::::..: ::: :::.: : : :. :.:.::::: CCDS43 AQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWK 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB6 EVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNP---HASTNGQLSVHTPKRES :::..:. :.. : .:..:::::. ::.. :.:: : :. .::: :: . .:.: CCDS43 EVTGVHSMEDN-GIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDS 300 310 320 330 340 350 300 310 320 330 340 350 pF1KB6 LSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQ :::: :: :::::::::::::..:::: .::::::.::::::::::::::::::::: CCDS43 SSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQ 360 370 380 390 400 410 360 370 380 390 400 410 pF1KB6 LELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTP ::.::.:..:::::::::::.. .::: .:.:::::::::.::. :.::::::.::::: CCDS43 LEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTP 420 430 440 450 460 470 420 430 440 450 460 470 pF1KB6 TAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTY :::.::.:::::::: .:. .:: ::::.:::::.:.:: .:: : ::::::.::::::: CCDS43 TAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSS-EIAPNYEFYKNADVRPPFTY 480 490 500 510 520 530 480 490 500 510 520 530 pF1KB6 ASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVK :.::::::.:: ..::::::::.:::: :::::::::::::::::::::::::::::::: CCDS43 ATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVK 540 550 560 570 580 590 540 550 560 570 580 590 pF1KB6 GAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASM ::::::::::.:::: :::.:.:.:.::. .: .: . :::.:::..::.:.:: .. .. CCDS43 GAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGL 600 610 620 630 640 650 600 610 620 630 640 650 pF1KB6 GNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLS : . ..: .:..:.:::...: .:: ..:::: ::. .: .::::::. :. . :.: CCDS43 INNASSGLLQAVHEDLNGSLDHIDSN-GNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMS 660 670 680 690 700 710 660 670 pF1KB6 LVTTANHSPDFDHDRDYEDEPVNEDME :::::::::... ::. :.::..::.: CCDS43 LVTTANHSPELEDDREIEEEPLSEDLE 720 730 740 >>CCDS5760.1 FOXP2 gene_id:93986|Hs108|chr7 (715 aa) initn: 1808 init1: 1010 opt: 2459 Z-score: 1620.9 bits: 310.4 E(32554): 5.8e-84 Smith-Waterman score: 2882; 63.9% identity (81.3% similar) in 718 aa overlap (9-677:9-715) 10 20 30 40 50 60 pF1KB6 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ : ::.: ::: . . :. :. :.:::.:.: . ......: : ::: : CCDS57 MMQESATETISNSSMNQNGMSTLSSQLDAGS-RDGRSSGDTSS-EVSTVELLHLQQQ--Q 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV :::.::::::: ::.::::::: .::: :::::::::::::::::::::::::::: CCDS57 ALQAARQLLLQ----QQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 60 70 80 90 100 110 130 140 150 160 pF1KB6 LSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQ------------------ :::::::.:::::::.::::::::::::::::::.::::::: CCDS57 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 120 130 140 150 160 170 170 180 190 pF1KB6 -------------------HAGKQPKEQQQ-------VATQQLAFQQQLLQMQQLQQQ-H : ::: ::::: .:.:::.:::::::::::::: : CCDS57 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQH 180 190 200 210 220 230 200 210 220 230 240 250 pF1KB6 LLSLQRQGLLTIQPGQPALPLQPLAQ-GMIPTELQQLWKEVTSAHTAEETTGNNHSSLDL :::::::::..: ::: :::.: : : :. :.:.::::::::..:. :.. : .:..::: CCDS57 LLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDN-GIKHGGLDL 240 250 260 270 280 290 260 270 280 290 300 310 pF1KB6 TTTCVSSSAPSKTSLIMNP---HASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWP ::. ::.. :.:: : :. .::: :: . .:.: :::: :: :::::::::: CCDS57 TTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWP 300 310 320 330 340 350 320 330 340 350 360 370 pF1KB6 GCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHV :::..:::: .::::::.:::::::::::::::::::::::.::.:..:::::::::::. CCDS57 GCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM 360 370 380 390 400 410 380 390 400 410 420 430 pF1KB6 KSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHT . .::: .:.:::::::::.::. :.::::::.::::::::.::.:::::::: .:. . CCDS57 RPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPN 420 430 440 450 460 470 440 450 460 470 480 490 pF1KB6 VGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEI :: ::::.:::::.:.:: .:: : ::::::.::::::::.::::::.:: ..::::::: CCDS57 VGAIRRRHSDKYNIPMSS-EIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEI 480 490 500 510 520 530 500 510 520 530 540 550 pF1KB6 YNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISG :.:::: ::::::::::::::::::::::::::::::::::::::::::.:::: :::.: CCDS57 YSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITG 540 550 560 570 580 590 560 570 580 590 600 610 pF1KB6 NPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAME .:.:.::. .: .: . :::.:::..::.:.:: .. .. : . ..: .:..:.:::... CCDS57 SPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLD 600 610 620 630 640 650 620 630 640 650 660 670 pF1KB6 HTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEP : .:: ..:::: ::. .: .::::::. :. . :.::::::::::... ::. :.:: CCDS57 HIDSN-GNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEP 660 670 680 690 700 pF1KB6 VNEDME ..::.: CCDS57 LSEDLE 710 >>CCDS34447.1 FOXP4 gene_id:116113|Hs108|chr6 (680 aa) initn: 1574 init1: 768 opt: 2366 Z-score: 1560.6 bits: 299.1 E(32554): 1.3e-80 Smith-Waterman score: 2370; 57.2% identity (76.7% similar) in 701 aa overlap (1-676:1-679) 10 20 30 40 pF1KB6 MMQESGTETKSNGSAIQNG-----------SGGSNHLLECGGLREGRSNGETPAVDIGAA :: ::..:: .. . ::: :::.. : :: ..: ... : CCDS34 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGRE-VTTGADSNGEMSPA 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 DLAHAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRND-KQPA--LQVPVSVAMMTPQV .: : :::: :::::::.:::: .:::.:: :: :: : .:::::::::.::. CCDS34 ELLHFQQQQ--ALQVARQFLLQQ-----ASGLSSPGNNDSKQSASAVQVPVSVAMMSPQM 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 ITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGK .:::::::: ::: :::.::::::::::: ::::.::::::::.:::: ::.::: CCDS34 LTPQQMQQI-----LSPPQLQALLQQQQALMLQ--QLQEYYKKQQEQLHLQLLTQQQAGK 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 QPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMI-P :. .. ....::::::::::::::::::::.::::::...::.: . ::: : :. . : CCDS34 -PQPKEALGNKQLAFQQQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCP 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 TELQQLWK-EVTSAHTAEETTGNNHSSLDLTTTCVSSS---APSKTSLIMNPHASTNGQL :.: :::: : . .. ::... .. .:::: : .... :: :.: .. :. ::: CCDS34 TDLPQLWKGEGAPGQPAEDSV--KQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQP 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 SVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQC .: : .:.: :::: : :::::::: :::::::..:::. .:.::::.:::::::::::: CCDS34 TVLTSRRDSSSHEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQC 290 300 310 320 330 340 350 360 370 380 390 pF1KB6 RVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLV-SSVTLSK---SASE :::::::::::.::::..:::::::.:::.. .::: :::: : .: ..:: ::.. CCDS34 RVQMQVVQQLEIQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAAD 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB6 ASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQE . :..: : ::. .::.::. : . ..:.: :: ::: :::. :::: ..:::.: CCDS34 SFPDGLVHPPTSAAAPVTPLR--PPGLGSASLHGGGPARRRSSDKFCSPISS-ELAQNHE 410 420 430 440 450 460 470 480 490 500 510 pF1KB6 FYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNL :::::.:::::::::::::::::.:..:::::::::::::::::::::.::::::::::: CCDS34 FYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNL 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB6 SLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASM ::::::::::::::::::::: :.::::: :..:.:.:.::: :. .: . :::. ::.. CCDS34 SLHKCFVRVENVKGAVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGA-LNASYQAAL 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB6 AENSIPLYTTASMGNP-TLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVK ::.:.:: .. .: :: . ..: ...... .: :: :.: : :: : : :.:: CCDS34 AESSFPLLNSPGMLNPGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVK 580 590 600 610 620 630 640 650 660 670 pF1KB6 EEPLDPEEAEGPLSLVTTANHSPDFD-HDRDYEDEPVNEDME ::: . :: . : . . : : . .::: :.: .:.. CCDS34 EEPAEAEEDRQPGPPLGAPNPSASGPPEDRDLEEELPGEELS 640 650 660 670 680 677 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:24:33 2016 done: Sat Nov 5 14:24:34 2016 Total Scan time: 3.560 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]