Result of FASTA (omim) for
pF1KB6243
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6243, 753 aa
1>>>pF1KB6243 753 - 753 aa - 753 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.7962+/-0.000462; mu= -17.1758+/- 0.029
mean_var=613.4146+/-131.630, 0's: 0 Z-trim(123.8): 1361 B-trim: 0 in 0/59
Lambda= 0.051784
statistics sampled from 42737 (44283) to 42737 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.519), width: 16
Scan time: 14.680
The best scores are: opt bits E(85289)
NP_005946 (OMIM: 600172) metal regulatory transcri ( 753) 5093 395.8 3.4e-109
XP_011539793 (OMIM: 600172) PREDICTED: metal regul ( 753) 5093 395.8 3.4e-109
XP_011539795 (OMIM: 600172) PREDICTED: metal regul ( 595) 4014 315.1 5.2e-85
XP_011539796 (OMIM: 600172) PREDICTED: metal regul ( 444) 2925 233.7 1.3e-60
XP_016866744 (OMIM: 194549) PREDICTED: zinc finger ( 517) 581 58.6 7.6e-08
XP_011513158 (OMIM: 194549) PREDICTED: zinc finger ( 519) 581 58.6 7.6e-08
XP_011513156 (OMIM: 194549) PREDICTED: zinc finger ( 526) 581 58.6 7.7e-08
XP_011513157 (OMIM: 194549) PREDICTED: zinc finger ( 526) 581 58.6 7.7e-08
XP_016866746 (OMIM: 194549) PREDICTED: zinc finger ( 462) 579 58.4 7.8e-08
NP_003418 (OMIM: 194549) zinc finger protein 76 is ( 570) 581 58.6 8.2e-08
XP_016866738 (OMIM: 194549) PREDICTED: zinc finger ( 570) 581 58.6 8.2e-08
XP_011513152 (OMIM: 194549) PREDICTED: zinc finger ( 579) 581 58.6 8.3e-08
XP_011513151 (OMIM: 194549) PREDICTED: zinc finger ( 579) 581 58.6 8.3e-08
XP_016866737 (OMIM: 194549) PREDICTED: zinc finger ( 582) 581 58.6 8.3e-08
XP_011513148 (OMIM: 194549) PREDICTED: zinc finger ( 591) 581 58.7 8.4e-08
XP_011513149 (OMIM: 194549) PREDICTED: zinc finger ( 591) 581 58.7 8.4e-08
NP_001278961 (OMIM: 194549) zinc finger protein 76 ( 515) 579 58.4 8.4e-08
XP_016866745 (OMIM: 194549) PREDICTED: zinc finger ( 515) 579 58.4 8.4e-08
XP_016866742 (OMIM: 194549) PREDICTED: zinc finger ( 524) 579 58.5 8.5e-08
XP_016866743 (OMIM: 194549) PREDICTED: zinc finger ( 524) 579 58.5 8.5e-08
XP_016866741 (OMIM: 194549) PREDICTED: zinc finger ( 527) 579 58.5 8.6e-08
XP_016866740 (OMIM: 194549) PREDICTED: zinc finger ( 536) 579 58.5 8.7e-08
XP_016882743 (OMIM: 606740) PREDICTED: zinc finger ( 349) 529 54.6 8.5e-07
NP_001275689 (OMIM: 606740) zinc finger protein 18 ( 349) 529 54.6 8.5e-07
XP_016882745 (OMIM: 606740) PREDICTED: zinc finger ( 349) 529 54.6 8.5e-07
NP_001275691 (OMIM: 606740) zinc finger protein 18 ( 349) 529 54.6 8.5e-07
NP_001275690 (OMIM: 606740) zinc finger protein 18 ( 349) 529 54.6 8.5e-07
XP_016882742 (OMIM: 606740) PREDICTED: zinc finger ( 349) 529 54.6 8.5e-07
XP_016882744 (OMIM: 606740) PREDICTED: zinc finger ( 349) 529 54.6 8.5e-07
XP_016882741 (OMIM: 606740) PREDICTED: zinc finger ( 349) 529 54.6 8.5e-07
XP_016882739 (OMIM: 606740) PREDICTED: zinc finger ( 349) 529 54.6 8.5e-07
XP_016882740 (OMIM: 606740) PREDICTED: zinc finger ( 349) 529 54.6 8.5e-07
NP_001265438 (OMIM: 606740) zinc finger protein 18 ( 665) 537 55.4 8.9e-07
NP_001278562 (OMIM: 606740) zinc finger protein 18 ( 665) 537 55.4 8.9e-07
NP_001265437 (OMIM: 606740) zinc finger protein 18 ( 667) 537 55.4 8.9e-07
NP_001275688 (OMIM: 606740) zinc finger protein 18 ( 691) 537 55.4 9.1e-07
NP_037388 (OMIM: 606740) zinc finger protein 180 i ( 692) 537 55.4 9.1e-07
XP_011525582 (OMIM: 606740) PREDICTED: zinc finger ( 734) 537 55.5 9.5e-07
XP_011518659 (OMIM: 605015) PREDICTED: zinc finger ( 592) 532 55.0 1.1e-06
XP_005253186 (OMIM: 605015) PREDICTED: zinc finger ( 592) 532 55.0 1.1e-06
XP_006718372 (OMIM: 605015) PREDICTED: zinc finger ( 592) 532 55.0 1.1e-06
XP_016873758 (OMIM: 605015) PREDICTED: zinc finger ( 592) 532 55.0 1.1e-06
XP_006718371 (OMIM: 605015) PREDICTED: zinc finger ( 606) 532 55.0 1.1e-06
XP_005253185 (OMIM: 605015) PREDICTED: zinc finger ( 606) 532 55.0 1.1e-06
NP_037381 (OMIM: 605015) zinc finger protein 214 [ ( 606) 532 55.0 1.1e-06
XP_011518657 (OMIM: 605015) PREDICTED: zinc finger ( 617) 532 55.0 1.1e-06
NP_001295198 (OMIM: 194628) zinc finger protein 12 ( 390) 513 53.4 2.1e-06
NP_001008727 (OMIM: 194628) zinc finger protein 12 ( 390) 513 53.4 2.1e-06
XP_016882728 (OMIM: 194628) PREDICTED: zinc finger ( 390) 513 53.4 2.1e-06
NP_066358 (OMIM: 194556) zinc finger protein 14 [H ( 642) 518 54.0 2.3e-06
>>NP_005946 (OMIM: 600172) metal regulatory transcriptio (753 aa)
initn: 5093 init1: 5093 opt: 5093 Z-score: 2081.5 bits: 395.8 E(85289): 3.4e-109
Smith-Waterman score: 5093; 100.0% identity (100.0% similar) in 753 aa overlap (1-753:1-753)
10 20 30 40 50 60
pF1KB6 MGEHSPDNNIIYFEAEEDELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGEHSPDNNIIYFEAEEDELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 FLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 STQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 STQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 DLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 LVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 NHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 TTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERASSRRKGCSSPPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERASSRRKGCSSPPPPE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB6 PSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQAETPSDPQTETLSAMDVSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQAETPSDPQTETLSAMDVSEF
670 680 690 700 710 720
730 740 750
pF1KB6 LSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK
:::::::::::::::::::::::::::::::::
NP_005 LSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK
730 740 750
>>XP_011539793 (OMIM: 600172) PREDICTED: metal regulator (753 aa)
initn: 5093 init1: 5093 opt: 5093 Z-score: 2081.5 bits: 395.8 E(85289): 3.4e-109
Smith-Waterman score: 5093; 100.0% identity (100.0% similar) in 753 aa overlap (1-753:1-753)
10 20 30 40 50 60
pF1KB6 MGEHSPDNNIIYFEAEEDELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGEHSPDNNIIYFEAEEDELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 FLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 STQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 DLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 LVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 NHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 TTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERASSRRKGCSSPPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERASSRRKGCSSPPPPE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB6 PSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQAETPSDPQTETLSAMDVSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQAETPSDPQTETLSAMDVSEF
670 680 690 700 710 720
730 740 750
pF1KB6 LSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK
:::::::::::::::::::::::::::::::::
XP_011 LSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK
730 740 750
>>XP_011539795 (OMIM: 600172) PREDICTED: metal regulator (595 aa)
initn: 4014 init1: 4014 opt: 4014 Z-score: 1647.2 bits: 315.1 E(85289): 5.2e-85
Smith-Waterman score: 4014; 100.0% identity (100.0% similar) in 589 aa overlap (1-589:1-589)
10 20 30 40 50 60
pF1KB6 MGEHSPDNNIIYFEAEEDELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGEHSPDNNIIYFEAEEDELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 FLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 STQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 DLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 LVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 NHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFF
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIVGKQDS
550 560 570 580 590
610 620 630 640 650 660
pF1KB6 TTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERASSRRKGCSSPPPPE
>>XP_011539796 (OMIM: 600172) PREDICTED: metal regulator (444 aa)
initn: 2925 init1: 2925 opt: 2925 Z-score: 1209.1 bits: 233.7 E(85289): 1.3e-60
Smith-Waterman score: 2925; 100.0% identity (100.0% similar) in 444 aa overlap (310-753:1-444)
280 290 300 310 320 330
pF1KB6 VRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLS
::::::::::::::::::::::::::::::
XP_011 MKGHDNKGHSYNALPQHNGSEDTNHSLCLS
10 20 30
340 350 360 370 380 390
pF1KB6 DLSLLSTDSELRENSSTTQGQDLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSLLSTDSELRENSSTTQGQDLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNG
40 50 60 70 80 90
400 410 420 430 440 450
pF1KB6 DAESVSDVPPSTGNSASLSLPLVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAESVSDVPPSTGNSASLSLPLVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFG
100 110 120 130 140 150
460 470 480 490 500 510
pF1KB6 NPPALLQPPEVPVPHSTQFAANHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPPALLQPPEVPVPHSTQFAANHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAP
160 170 180 190 200 210
520 530 540 550 560 570
pF1KB6 APPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGA
220 230 240 250 260 270
580 590 600 610 620 630
pF1KB6 TSSPQNQEQIQQASKVEKVFFTTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSPQNQEQIQQASKVEKVFFTTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACR
280 290 300 310 320 330
640 650 660 670 680 690
pF1KB6 DSAKERASSRRKGCSSPPPPEPSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAKERASSRRKGCSSPPPPEPSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSR
340 350 360 370 380 390
700 710 720 730 740 750
pF1KB6 QAETPSDPQTETLSAMDVSEFLSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAETPSDPQTETLSAMDVSEFLSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK
400 410 420 430 440
>>XP_016866744 (OMIM: 194549) PREDICTED: zinc finger pro (517 aa)
initn: 575 init1: 351 opt: 581 Z-score: 261.8 bits: 58.6 E(85289): 7.6e-08
Smith-Waterman score: 613; 34.9% identity (61.7% similar) in 332 aa overlap (109-424:80-399)
80 90 100 110 120 130
pF1KB6 EGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPET-KRKEV
: :. :: . .: .:. :.. : ..:
XP_016 RAPSWPYRQRWAWRTWQQRMMRASVQTQWWPWSS-MPARLFPQVLH-DSQIPRNGKGQQV
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB6 --KRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHT
. ..: ..:: : :.:: .:..:...: :. . :. .::::: :.:.:. :::.::
XP_016 GDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHT
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB6 KEKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESEGCSKYFTTLSDLRK-HIRTH
:::..: . : :::.: :. : : ::: . :.: :::.. ::: :..:: :.:::
XP_016 GEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTT-SNIRKVHVRTH
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB6 TGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGH
:::.:. : . ::..:... . :.::: ::::.:. : :: : :. :: .: :
XP_016 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVH
230 240 250 260 270 280
320 330 340 350 360
pF1KB6 DNK--------GHSY---NALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQDL
. :..: ..: .:. : . . . : ...:. :.. ..
XP_016 THCKPYTCSTCGKTYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 STISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLPLV
. : : . : .. : . : :.: .:: .: : .:. . . ....::: :
XP_016 KR--PRIAYLSEVKEERD----DIPAQVAMVTEE-DG-APQVALITQDGAQQVSLS-PED
350 360 370 380 390
430 440 450 460 470 480
pF1KB6 LQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAANH
::
XP_016 LQALGSAISMVTQHGSTTLTIPSPDADLATSGTHTVTMVSADGTQTQPVTIITSGAVVAE
400 410 420 430 440 450
>>XP_011513158 (OMIM: 194549) PREDICTED: zinc finger pro (519 aa)
initn: 575 init1: 351 opt: 581 Z-score: 261.8 bits: 58.6 E(85289): 7.6e-08
Smith-Waterman score: 615; 29.6% identity (55.6% similar) in 446 aa overlap (109-536:73-489)
80 90 100 110 120 130
pF1KB6 EGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPET-KRKEV
: :. :: . .: .:. :.. : ..:
XP_011 RAPSWPYRQRWAWRTWQQRMMRASVQTQWWPWSS-MPARLFPQVLH-DSQIPRNGKGQQV
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB6 --KRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHT
. ..: ..:: : :.:: .:..:...: :. . :. .::::: :.:.:. :::.::
XP_011 GDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHT
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB6 KEKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESEGCSKYFTTLSDLRK-HIRTH
:::..: . : :::.: :. : : ::: . :.: :::.. ::: :..:: :.:::
XP_011 GEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTT-SNIRKVHVRTH
170 180 190 200 210
260 270 280 290 300 310
pF1KB6 TGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGH
:::.:. : . ::..:... . :.::: ::::.:. : :: : :. :: .:
XP_011 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKH----
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB6 DNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ-DLSTISPAIIFE
: :. . . : : . :: : .. ...:. . . : ..:
XP_011 ----HVV-----HTHCKPYTCSTCGKTYRQTST---LAMHKRSAHGELEATEESEQALYE
280 290 300 310 320
380 390 400 410 420
pF1KB6 SMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPS----TGNSASLSLPLVLQPGLS
.. : .: .:.: .. : .:.: . : .... .. :. : : .
XP_011 QQ-QLEAASAAEESPPPKRPRIAYLSEVKEERDDIPAQVAMVTEEDGAPQVALITQDGAQ
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB6 EPPQPLLPASAPSAPPPAPSLGPG-SQQAAFGNPPALLQPPEVPVPHSTQFAANHQEFLP
. . .: .:: . :. . :. . :.. . : ...
XP_011 Q---------VSLSPEDLQALGSAISMVTQHGSTTLTIPSPDADLATSGTHTVTMVSADG
390 400 410 420 430
490 500 510 520 530 540
pF1KB6 HPQAPQPIVPGLSVVAGASASA-------AAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
: :. . .::: :. : : .:.: .. :.... : .::.:
XP_011 TQTQPVTIITSGAVVAEDSSVASLRHQQVALLATANGTHIAVQDNSDGSPPVVQALHHFV
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB6 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFF
XP_011 SLFLHLEMKEADVDDHHGSLQPVLPP
500 510
>>XP_011513156 (OMIM: 194549) PREDICTED: zinc finger pro (526 aa)
initn: 575 init1: 351 opt: 581 Z-score: 261.7 bits: 58.6 E(85289): 7.7e-08
Smith-Waterman score: 615; 29.6% identity (55.6% similar) in 446 aa overlap (109-536:80-496)
80 90 100 110 120 130
pF1KB6 EGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPET-KRKEV
: :. :: . .: .:. :.. : ..:
XP_011 RAPSWPYRQRWAWRTWQQRMMRASVQTQWWPWSS-MPARLFPQVLH-DSQIPRNGKGQQV
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB6 --KRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHT
. ..: ..:: : :.:: .:..:...: :. . :. .::::: :.:.:. :::.::
XP_011 GDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHT
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB6 KEKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESEGCSKYFTTLSDLRK-HIRTH
:::..: . : :::.: :. : : ::: . :.: :::.. ::: :..:: :.:::
XP_011 GEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTT-SNIRKVHVRTH
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB6 TGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGH
:::.:. : . ::..:... . :.::: ::::.:. : :: : :. :: .:
XP_011 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKH----
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB6 DNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ-DLSTISPAIIFE
: :. . . : : . :: : .. ...:. . . : ..:
XP_011 ----HVV-----HTHCKPYTCSTCGKTYRQTST---LAMHKRSAHGELEATEESEQALYE
290 300 310 320 330
380 390 400 410 420
pF1KB6 SMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPS----TGNSASLSLPLVLQPGLS
.. : .: .:.: .. : .:.: . : .... .. :. : : .
XP_011 QQ-QLEAASAAEESPPPKRPRIAYLSEVKEERDDIPAQVAMVTEEDGAPQVALITQDGAQ
340 350 360 370 380
430 440 450 460 470 480
pF1KB6 EPPQPLLPASAPSAPPPAPSLGPG-SQQAAFGNPPALLQPPEVPVPHSTQFAANHQEFLP
. . .: .:: . :. . :. . :.. . : ...
XP_011 Q---------VSLSPEDLQALGSAISMVTQHGSTTLTIPSPDADLATSGTHTVTMVSADG
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB6 HPQAPQPIVPGLSVVAGASASA-------AAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
: :. . .::: :. : : .:.: .. :.... : .::.:
XP_011 TQTQPVTIITSGAVVAEDSSVASLRHQQVALLATANGTHIAVQDNSDGSPPVVQALHHFV
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB6 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFF
XP_011 SLFLHLEMKEADVDDHHGSLQPVLPP
510 520
>>XP_011513157 (OMIM: 194549) PREDICTED: zinc finger pro (526 aa)
initn: 575 init1: 351 opt: 581 Z-score: 261.7 bits: 58.6 E(85289): 7.7e-08
Smith-Waterman score: 615; 29.6% identity (55.6% similar) in 446 aa overlap (109-536:80-496)
80 90 100 110 120 130
pF1KB6 EGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPET-KRKEV
: :. :: . .: .:. :.. : ..:
XP_011 RAPSWPYRQRWAWRTWQQRMMRASVQTQWWPWSS-MPARLFPQVLH-DSQIPRNGKGQQV
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB6 --KRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHT
. ..: ..:: : :.:: .:..:...: :. . :. .::::: :.:.:. :::.::
XP_011 GDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHT
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB6 KEKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESEGCSKYFTTLSDLRK-HIRTH
:::..: . : :::.: :. : : ::: . :.: :::.. ::: :..:: :.:::
XP_011 GEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTT-SNIRKVHVRTH
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB6 TGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGH
:::.:. : . ::..:... . :.::: ::::.:. : :: : :. :: .:
XP_011 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKH----
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB6 DNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQ-DLSTISPAIIFE
: :. . . : : . :: : .. ...:. . . : ..:
XP_011 ----HVV-----HTHCKPYTCSTCGKTYRQTST---LAMHKRSAHGELEATEESEQALYE
290 300 310 320 330
380 390 400 410 420
pF1KB6 SMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPS----TGNSASLSLPLVLQPGLS
.. : .: .:.: .. : .:.: . : .... .. :. : : .
XP_011 QQ-QLEAASAAEESPPPKRPRIAYLSEVKEERDDIPAQVAMVTEEDGAPQVALITQDGAQ
340 350 360 370 380
430 440 450 460 470 480
pF1KB6 EPPQPLLPASAPSAPPPAPSLGPG-SQQAAFGNPPALLQPPEVPVPHSTQFAANHQEFLP
. . .: .:: . :. . :. . :.. . : ...
XP_011 Q---------VSLSPEDLQALGSAISMVTQHGSTTLTIPSPDADLATSGTHTVTMVSADG
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB6 HPQAPQPIVPGLSVVAGASASA-------AAVASAVAAPAPPQSTTEPLPAMVQTLPLGA
: :. . .::: :. : : .:.: .. :.... : .::.:
XP_011 TQTQPVTIITSGAVVAEDSSVASLRHQQVALLATANGTHIAVQDNSDGSPPVVQALHHFV
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB6 NSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFF
XP_011 SLFLHLEMKEADVDDHHGSLQPVLPP
510 520
>>XP_016866746 (OMIM: 194549) PREDICTED: zinc finger pro (462 aa)
initn: 809 init1: 351 opt: 579 Z-score: 261.6 bits: 58.4 E(85289): 7.8e-08
Smith-Waterman score: 608; 42.9% identity (69.0% similar) in 210 aa overlap (109-313:80-286)
80 90 100 110 120 130
pF1KB6 EGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPET-KRKEV
: :. :: . .: .:. :.. : ..:
XP_016 RAPSWPYRQRWAWRTWQQRMMRASVQTQWWPWSS-MPARLFPQVLH-DSQIPRNGKGQQV
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB6 --KRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHT
. ..: ..:: : :.:: .:..:...: :. . :. .::::: :.:.:. :::.::
XP_016 GDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHT
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB6 KEKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESEGCSKYFTTLSDLRK-HIRTH
:::..: . : :::.: :. : : ::: . :.: :::.. ::: :..:: :.:::
XP_016 GEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTT-SNIRKVHVRTH
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB6 TGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGH
:::.:. : . ::..:... . :.::: ::::.:. : :: : :. :: .: :
XP_016 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVH
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB6 DNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQDLSTISPAIIFES
XP_016 THCKPYTCSTCGKTYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPP
290 300 310 320 330 340
>>NP_003418 (OMIM: 194549) zinc finger protein 76 isofor (570 aa)
initn: 575 init1: 351 opt: 581 Z-score: 261.3 bits: 58.6 E(85289): 8.2e-08
Smith-Waterman score: 620; 30.6% identity (59.1% similar) in 445 aa overlap (2-424:25-452)
10 20 30
pF1KB6 MGEHSPDNNIIYFE----AEEDELTPDDKMLRFVDKN
::. ....: .: : ..: . . : : : .
NP_003 MESLGLHTVTLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQKEALSFEDGQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 GLVPSSSGTVYDRTTVLIEQDPGTLED-EDDDGQCGE-HLPFLVGGEEGFHLIDHEAMSQ
. ... .: . : ::.::: . .::. . : : : .: . .. :.
NP_003 PVQLEDGSMAYIHRTPREGYDPSTLEAVQLEDGSTAYIHHPVAVPSESTILAVQTEV---
70 80 90 100 110
100 110 120 130 140
pF1KB6 GYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPET-KRKEV--KRYQCTFEGCP
: .. . . :. .. . . . . .. . .:. :.. : ..: . ..: ..::
NP_003 G-LEDLAAEDDEGFSAD---AVVALEQYASKVLHDSQIPRNGKGQQVGDRAFRCGYKGCG
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB6 RTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCE
: :.:: .:..:...: :. . :. .::::: :.:.:. :::.:: :::..: . :
NP_003 RLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCS
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB6 KAFNTLYRLKAHQRLHTG-KTFNCESEGCSKYFTTLSDLRK-HIRTHTGEKPFRCDHDGC
:::.: :. : : ::: . :.: :::.. ::: :..:: :.::::::.:. : . :
NP_003 KAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTT-SNIRKVHVRTHTGERPYTCPEPHC
240 250 260 270 280 290
270 280 290 300 310
pF1KB6 GKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNK--------GH
:..:... . :.::: ::::.:. : :: : :. :: .: : . :.
NP_003 GRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSTCGK
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB6 SY---NALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQDLSTISPAIIFESMF
.: ..: .:. : . . . : ...:. :.. .. . : : . :
NP_003 TYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPPKR--PRIAYLSEV
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB6 QNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLPLVLQPGLSEPPQPLL
.. : . : :.: .:: .: : .:. . . ....::: : ::
NP_003 KEERD----DIPAQVAMVTEE-DG-APQVALITQDGAQQVSLS-PEDLQALGSAISMVTQ
420 430 440 450 460
440 450 460 470 480 490
pF1KB6 PASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAANHQEFLPHPQAPQPI
NP_003 HGSTTLTIPSPDADLATSGTHTVTMVSADGTQTQPVTIITSGAVVAEDSSVASLRHQQVA
470 480 490 500 510 520
753 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:26:30 2016 done: Sat Nov 5 14:26:32 2016
Total Scan time: 14.680 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]