Result of FASTA (omim) for
pF1KB6245
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6245, 753 aa
1>>>pF1KB6245 753 - 753 aa - 753 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.8887+/-0.000384; mu= -10.7764+/- 0.024
mean_var=341.7607+/-69.791, 0's: 0 Z-trim(123.0): 161 B-trim: 50 in 1/58
Lambda= 0.069377
statistics sampled from 41834 (41996) to 41834 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.492), width: 16
Scan time: 13.690
The best scores are: opt bits E(85289)
NP_848511 (OMIM: 606698) transcription factor SOX- ( 753) 5126 527.2 9.4e-149
NP_008948 (OMIM: 606698) transcription factor SOX- ( 501) 3104 324.7 5.6e-88
XP_005265860 (OMIM: 606698) PREDICTED: transcripti ( 448) 2985 312.8 2e-84
NP_001295094 (OMIM: 606698) transcription factor S ( 448) 2985 312.8 2e-84
XP_011532722 (OMIM: 606698) PREDICTED: transcripti ( 448) 2985 312.8 2e-84
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 351 49.2 5.1e-05
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388) 343 48.3 7.1e-05
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240) 317 45.6 0.00029
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276) 299 43.8 0.0011
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204) 292 43.1 0.0014
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233) 287 42.6 0.0023
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 294 43.5 0.0025
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 282 42.2 0.0041
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446) 285 42.6 0.0044
NP_821078 (OMIM: 604975,616803) transcription fact ( 377) 283 42.3 0.0044
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415) 283 42.3 0.0048
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391) 279 41.9 0.006
NP_001248343 (OMIM: 604975,616803) transcription f ( 642) 283 42.4 0.0069
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715) 283 42.5 0.0075
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715) 283 42.5 0.0075
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715) 283 42.5 0.0075
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715) 283 42.5 0.0075
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716) 283 42.5 0.0075
NP_001317714 (OMIM: 604975,616803) transcription f ( 728) 283 42.5 0.0076
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729) 283 42.5 0.0076
NP_694534 (OMIM: 604975,616803) transcription fact ( 750) 283 42.5 0.0078
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750) 283 42.5 0.0078
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751) 283 42.5 0.0078
NP_001248344 (OMIM: 604975,616803) transcription f ( 753) 283 42.5 0.0078
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754) 283 42.5 0.0078
NP_008871 (OMIM: 604975,616803) transcription fact ( 763) 283 42.5 0.0079
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764) 283 42.5 0.0079
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792) 283 42.5 0.0082
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793) 283 42.5 0.0082
NP_071899 (OMIM: 610928,613674) transcription fact ( 414) 275 41.5 0.0083
XP_005270146 (OMIM: 125853,602228) PREDICTED: tran ( 584) 279 42.0 0.0084
XP_005270142 (OMIM: 125853,602228) PREDICTED: tran ( 607) 279 42.0 0.0087
NP_003099 (OMIM: 600898,615866) transcription fact ( 441) 275 41.6 0.0088
XP_005270135 (OMIM: 125853,602228) PREDICTED: tran ( 655) 279 42.1 0.0092
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621) 278 41.9 0.0095
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622) 278 41.9 0.0095
NP_001139283 (OMIM: 607257) transcription factor S ( 801) 281 42.3 0.0095
>>NP_848511 (OMIM: 606698) transcription factor SOX-30 i (753 aa)
initn: 5126 init1: 5126 opt: 5126 Z-score: 2791.5 bits: 527.2 E(85289): 9.4e-149
Smith-Waterman score: 5126; 100.0% identity (100.0% similar) in 753 aa overlap (1-753:1-753)
10 20 30 40 50 60
pF1KB6 MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLPTPAVQSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLPTPAVQSPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 PVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTVKQPTPVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 PVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTVKQPTPVSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 ESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVYQPPPLGHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVYQPPPLGHP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 ATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYYEDRYPKHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYYEDRYPKHE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB6 GIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVPQLDIGTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 GIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVPQLDIGTLE
670 680 690 700 710 720
730 740 750
pF1KB6 NVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
:::::::::::::::::::::::::::::::::
NP_848 NVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
730 740 750
>>NP_008948 (OMIM: 606698) transcription factor SOX-30 i (501 aa)
initn: 3104 init1: 3104 opt: 3104 Z-score: 1700.4 bits: 324.7 E(85289): 5.6e-88
Smith-Waterman score: 3104; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KB6 MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLPTPAVQSPS
::::::::::::::::::::::::::::::::::::::::::
NP_008 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVVHALTVGLPLAMEIFRVQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 PVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTVKQPTPVSL
NP_008 CQNALVIMKTGTQNMRVSFQL
490 500
>>XP_005265860 (OMIM: 606698) PREDICTED: transcription f (448 aa)
initn: 2985 init1: 2985 opt: 2985 Z-score: 1636.8 bits: 312.8 E(85289): 2e-84
Smith-Waterman score: 2985; 100.0% identity (100.0% similar) in 431 aa overlap (323-753:18-448)
300 310 320 330 340 350
pF1KB6 PVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHR
::::::::::::::::::::::::::::::
XP_005 MEKCCRGKEQSLLCIQQGIPDTPFSKDRNGHVKRPMNAFMVWARIHR
10 20 30 40
360 370 380 390 400 410
pF1KB6 PALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGK
50 60 70 80 90 100
420 430 440 450 460 470
pF1KB6 RKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLP
110 120 130 140 150 160
480 490 500 510 520 530
pF1KB6 TPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTV
170 180 190 200 210 220
540 550 560 570 580 590
pF1KB6 KQPTPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQPTPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVY
230 240 250 260 270 280
600 610 620 630 640 650
pF1KB6 QPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYY
290 300 310 320 330 340
660 670 680 690 700 710
pF1KB6 EDRYPKHEGIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDRYPKHEGIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVP
350 360 370 380 390 400
720 730 740 750
pF1KB6 QLDIGTLENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
:::::::::::::::::::::::::::::::::::::::::
XP_005 QLDIGTLENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
410 420 430 440
>>NP_001295094 (OMIM: 606698) transcription factor SOX-3 (448 aa)
initn: 2985 init1: 2985 opt: 2985 Z-score: 1636.8 bits: 312.8 E(85289): 2e-84
Smith-Waterman score: 2985; 100.0% identity (100.0% similar) in 431 aa overlap (323-753:18-448)
300 310 320 330 340 350
pF1KB6 PVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHR
::::::::::::::::::::::::::::::
NP_001 MEKCCRGKEQSLLCIQQGIPDTPFSKDRNGHVKRPMNAFMVWARIHR
10 20 30 40
360 370 380 390 400 410
pF1KB6 PALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGK
50 60 70 80 90 100
420 430 440 450 460 470
pF1KB6 RKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLP
110 120 130 140 150 160
480 490 500 510 520 530
pF1KB6 TPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTV
170 180 190 200 210 220
540 550 560 570 580 590
pF1KB6 KQPTPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQPTPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVY
230 240 250 260 270 280
600 610 620 630 640 650
pF1KB6 QPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYY
290 300 310 320 330 340
660 670 680 690 700 710
pF1KB6 EDRYPKHEGIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRYPKHEGIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVP
350 360 370 380 390 400
720 730 740 750
pF1KB6 QLDIGTLENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
:::::::::::::::::::::::::::::::::::::::::
NP_001 QLDIGTLENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
410 420 430 440
>>XP_011532722 (OMIM: 606698) PREDICTED: transcription f (448 aa)
initn: 2985 init1: 2985 opt: 2985 Z-score: 1636.8 bits: 312.8 E(85289): 2e-84
Smith-Waterman score: 2985; 100.0% identity (100.0% similar) in 431 aa overlap (323-753:18-448)
300 310 320 330 340 350
pF1KB6 PVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHR
::::::::::::::::::::::::::::::
XP_011 MEKCCRGKEQSLLCIQQGIPDTPFSKDRNGHVKRPMNAFMVWARIHR
10 20 30 40
360 370 380 390 400 410
pF1KB6 PALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGK
50 60 70 80 90 100
420 430 440 450 460 470
pF1KB6 RKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLP
110 120 130 140 150 160
480 490 500 510 520 530
pF1KB6 TPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTV
170 180 190 200 210 220
540 550 560 570 580 590
pF1KB6 KQPTPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQPTPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVY
230 240 250 260 270 280
600 610 620 630 640 650
pF1KB6 QPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYY
290 300 310 320 330 340
660 670 680 690 700 710
pF1KB6 EDRYPKHEGIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDRYPKHEGIFSTLNRDYSFRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVP
350 360 370 380 390 400
720 730 740 750
pF1KB6 QLDIGTLENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
:::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIGTLENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
410 420 430 440
>>NP_000337 (OMIM: 114290,608160,616425) transcription f (509 aa)
initn: 312 init1: 263 opt: 351 Z-score: 211.1 bits: 49.2 E(85289): 5.1e-05
Smith-Waterman score: 394; 25.9% identity (49.9% similar) in 487 aa overlap (297-753:68-506)
270 280 290 300 310 320
pF1KB6 VPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPD
:. .. .:. : :..: . .
NP_000 GSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNG
40 50 60 70 80 90
330 340 350 360 370 380
pF1KB6 TPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPY
. ::.. :::::::::::::. : :: : .:::.: :: : :.: .:.:.
NP_000 S--SKNKP-HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPF
100 110 120 130 140 150
390 400 410 420 430 440
pF1KB6 YDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPT-TVYPYRSP
.::.... .:... : . :::: .:: . ... .: :. :: : . ::
NP_000 VEEAERLRVQHKKDHPDYKYQPR--RRKSVKNGQAEAEEATEQTHISPNAIFKALQADSP
160 170 180 190 200 210
450 460 470 480 490 500
pF1KB6 TYSVVIPSLQNPITHPVGETSPAIQLPTPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVY
: . ...: : .: ::: . .: : ::. :.. . ::
NP_000 HSSSGMSEVHSPGEHSGQSQGP----PTPPT---TPKTDVQPG---KADLKREGRPLPEG
220 230 240 250 260
510 520 530 540
pF1KB6 PALPPQRFT----GPSQTDT-HQLHSEATHTVKQPTP-------------VSLESANRIS
:: : : ..:. .... .. : : :. .. ::
NP_000 GRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTYTGSYGIS
270 280 290 300 310 320
550 560 570 580 590 600
pF1KB6 SSAST-AHARFATSTIQ-----PPREYSSVSPCPRSAPIPQASPIPHPHVYQPPPLGHPA
:.:.: : : . . : ::.. .. : :.. : :::.: .: . : .:
NP_000 STAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTL
330 340 350 360 370 380
610 620 630 640 650
pF1KB6 TLFGTPP----RFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLSYYEDRYP
: ... : : .. . :. :: : .: ..:. : ..: .: ::
NP_000 TTLSSEPGQSQRTHIKTEQLSPS-HY--SEQQQHSPQQIAYS--PFNLP----HYSPSYP
390 400 410 420 430
660 670 680 690 700 710
pF1KB6 KHEGIFSTLNRDYS-FRDYSSECTHSENSRSCENMNGTSYYNSHSHSGEENLNPVPQLDI
.. . ::. .. :: .:. .. ::. :.. .. .::. .
NP_000 P----ITRSQYDYTDHQNSSSYYSHAAGQ-------GTGLYSTFTY-----MNPAQR---
440 450 460 470
720 730 740 750
pF1KB6 GTLENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
..: : . :.. .. : : .. :. : .:
NP_000 ----PMYT-PIADTSGVPSIPQTHSPQHWEQPVYTQLTRP
480 490 500
>>NP_113627 (OMIM: 612202) transcription factor SOX-7 [H (388 aa)
initn: 377 init1: 294 opt: 343 Z-score: 208.6 bits: 48.3 E(85289): 7.1e-05
Smith-Waterman score: 362; 29.0% identity (51.5% similar) in 303 aa overlap (312-600:20-310)
290 300 310 320 330 340
pF1KB6 ELIRLTKVPLTPVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPM
:. :. : ..: : .: .....:::
NP_113 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPM
10 20 30 40
350 360 370 380 390 400
pF1KB6 NAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEF
:::::::. .: :: :: .:::.: .:: :. :. ::.:: :::.... .: ...
NP_113 NAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDY
50 60 70 80 90 100
410 420 430 440 450 460
pF1KB6 PGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHP
:.. :.:: ..:. . : : . .: . ... :: . ... . .
NP_113 PNYKYRPR--RKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDR-----
110 120 130 140 150 160
470 480 490 500 510 520
pF1KB6 VGETSPAIQLPT-PAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTD
:: ::. ::. . .:. . .. ..: . .::. : . : : ::
NP_113 -GEYSPGTALPSLRGCYHEGPAG--GGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTF
170 180 190 200 210
530 540 550 560 570
pF1KB6 -THQLHSEATHTVKQP-TPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSA
. . : : . : : : . : .: . . : : : .:: :
NP_113 FSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPG-VSMMSPVPGCP
220 230 240 250 260 270
580 590 600 610 620
pF1KB6 PIPQA-SPIP-HP-------HVYQ--PPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSS
: : :: :: :. : ::: ::
NP_113 PSPAYYSPATYHPLHSNLQAHLGQLSPPPE-HPGFDALDQLSQVELLGDMDRNEFDQYLN
280 290 300 310 320 330
630 640 650 660 670 680
pF1KB6 TCPYSRPPFGYGNFPSSMPECLSYYEDRYPKHEGIFSTLNRDYSFRDYSSECTHSENSRS
NP_113 TPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLADATATYYNSYSVS
340 350 360 370 380
>>NP_004180 (OMIM: 604747) transcription factor SOX-14 [ (240 aa)
initn: 349 init1: 296 opt: 317 Z-score: 197.6 bits: 45.6 E(85289): 0.00029
Smith-Waterman score: 346; 32.6% identity (54.8% similar) in 239 aa overlap (336-568:7-218)
310 320 330 340 350 360
pF1KB6 VKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNA
:.::::::::::.: .: .:. :: .:.
NP_004 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNS
10 20 30
370 380 390 400 410 420
pF1KB6 EISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFS
::: .:: ::. ::: .:.:: :::.... .: .: : . :.:: :: :
NP_004 EISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPR---RK--P--------
40 50 60 70 80
430 440 450 460 470 480
pF1KB6 GTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLPTPA--VQSPS--P
.:... . :.: : . . : . ::: .. .. : : :. :
NP_004 ---KNLLKKD-RYVFPL--PYLGDTDPLKAAGL--PVGASDGLLSAPEKARAFLPPASAP
90 100 110 120 130
490 500 510 520 530
pF1KB6 VTLFQPS--VSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTVKQPTPVS
.:..:. ::: : . : . ::: : .. .: . :: .:.:.
NP_004 YSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSPT-
140 150 160 170 180 190
540 550 560 570 580 590
pF1KB6 LESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPIPHPHVYQPPPLGH
. . . :: ...::.::: :
NP_004 --NPGYVVPCNCTA---WSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM
200 210 220 230 240
>>NP_009015 (OMIM: 604974) transcription factor SOX-21 [ (276 aa)
initn: 316 init1: 289 opt: 299 Z-score: 186.9 bits: 43.8 E(85289): 0.0011
Smith-Waterman score: 315; 27.7% identity (54.0% similar) in 274 aa overlap (336-587:7-269)
310 320 330 340 350 360
pF1KB6 VKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNA
::::::::::::.: .: .:. :: .:.
NP_009 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNS
10 20 30
370 380 390 400 410 420
pF1KB6 EISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPR--PG---KRKRFPLSV
::: .:: ::. :.: .:.:. :::.... : .: : . :.:: : :. .: . :
NP_009 EISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPV
40 50 60 70 80 90
430 440 450 460 470
pF1KB6 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSL-QNPITHPVGETSPAIQLPTP-----
..:... . . . . . ..: :: :: .. .. : .. :
NP_009 PYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAA
100 110 120 130 140 150
480 490 500 510 520
pF1KB6 ------AVQSPSPVTLFQPSVSSAAQVAVQDPSLPV-----YPALPPQRFTGPSQTDTHQ
:. . :: .:.. . :. :... .. .:: ::. : : . . .
NP_009 AAAAAAAAAAGSPYSLLDLG-SKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAA
160 170 180 190 200 210
530 540 550 560 570 580
pF1KB6 LHSEATHTVKQPTPVSLESANRISSSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQA
. . :: ..:.: . . : . :. . . .::: : . . ::
NP_009 AAAAGGHTHSHPSPGN--PGYMIPCNCSA----WPSPGLQPPLAYILLPGMGK----PQL
220 230 240 250 260
590 600 610 620 630 640
pF1KB6 SPIPHPHVYQPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPS
.: :
NP_009 DPYPAAYAAAL
270
>>NP_003131 (OMIM: 400044,400045,480000) sex-determining (204 aa)
initn: 309 init1: 280 opt: 292 Z-score: 185.1 bits: 43.1 E(85289): 0.0014
Smith-Waterman score: 292; 35.9% identity (62.7% similar) in 142 aa overlap (331-470:57-194)
310 320 330 340 350 360
pF1KB6 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP
.:: ::::::::.::.: .: .: ::
NP_003 ALRRSSSFLCTESCNSKYQCETGENSKGNVQDR---VKRPMNAFIVWSRDQRRKMALENP
30 40 50 60 70 80
370 380 390 400 410 420
pF1KB6 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV
:.::: ::: .:. :.: .: :...::::.. :::..:.. :.:: : : .: .
NP_003 RMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYRPRR-KAKMLPKNC
90 100 110 120 130 140
430 440 450 460 470
pF1KB6 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITH--PVGETSPAIQLPTPAVQS
: . . .. . : ::. ... ... . : :.. .: :
NP_003 SLLPADPASVLCSEVQLDNRLYRDDCTKATHSRMEHQLGHLPPINAASSPQQRDRYSHWT
150 160 170 180 190 200
480 490 500 510 520 530
pF1KB6 PSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTVKQPTPV
NP_003 KL
753 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:55:07 2016 done: Sat Nov 5 13:55:09 2016
Total Scan time: 13.690 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]