FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6246, 680 aa 1>>>pF1KB6246 680 - 680 aa - 680 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.7540+/-0.000365; mu= -4.5247+/- 0.023 mean_var=281.6650+/-59.046, 0's: 0 Z-trim(123.2): 195 B-trim: 1503 in 2/56 Lambda= 0.076420 statistics sampled from 42290 (42500) to 42290 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.498), width: 16 Scan time: 14.410 The best scores are: opt bits E(85289) NP_001012426 (OMIM: 608924) forkhead box protein P ( 680) 4570 517.3 7.6e-146 XP_006715054 (OMIM: 608924) PREDICTED: forkhead bo ( 679) 4553 515.4 2.8e-145 XP_011512591 (OMIM: 608924) PREDICTED: forkhead bo ( 687) 4546 514.6 4.8e-145 XP_016865722 (OMIM: 608924) PREDICTED: forkhead bo ( 687) 4546 514.6 4.8e-145 NP_001012427 (OMIM: 608924) forkhead box protein P ( 678) 4544 514.4 5.5e-145 XP_011512592 (OMIM: 608924) PREDICTED: forkhead bo ( 685) 4520 511.8 3.5e-144 XP_016865723 (OMIM: 608924) PREDICTED: forkhead bo ( 649) 4206 477.1 8.8e-134 XP_011512594 (OMIM: 608924) PREDICTED: forkhead bo ( 655) 3926 446.3 1.7e-124 XP_011512595 (OMIM: 608924) PREDICTED: forkhead bo ( 581) 3884 441.6 3.9e-123 XP_011512593 (OMIM: 608924) PREDICTED: forkhead bo ( 675) 3335 381.1 7.4e-105 NP_001231737 (OMIM: 605515,613670) forkhead box pr ( 676) 2382 276.0 3.1e-73 XP_005264794 (OMIM: 605515,613670) PREDICTED: fork ( 676) 2372 274.9 6.8e-73 XP_016861655 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2366 274.3 1.1e-72 XP_011531887 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2366 274.3 1.1e-72 XP_006713167 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2366 274.3 1.1e-72 XP_016861654 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2366 274.3 1.1e-72 NP_116071 (OMIM: 605515,613670) forkhead box prote ( 677) 2366 274.3 1.1e-72 NP_001231745 (OMIM: 605515,613670) forkhead box pr ( 677) 2366 274.3 1.1e-72 XP_006713166 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2366 274.3 1.1e-72 XP_006713165 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2366 274.3 1.1e-72 XP_011531886 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2366 274.3 1.1e-72 NP_001231743 (OMIM: 605515,613670) forkhead box pr ( 677) 2366 274.3 1.1e-72 XP_016861656 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2314 268.5 5.7e-71 XP_005264793 (OMIM: 605515,613670) PREDICTED: fork ( 678) 2312 268.3 6.6e-71 XP_005264792 (OMIM: 605515,613670) PREDICTED: fork ( 678) 2302 267.2 1.4e-70 NP_001231744 (OMIM: 605515,613670) forkhead box pr ( 679) 2300 267.0 1.7e-70 NP_683698 (OMIM: 602081,605317) forkhead box prote ( 732) 2189 254.8 8.5e-67 XP_005264799 (OMIM: 605515,613670) PREDICTED: fork ( 576) 2177 253.4 1.8e-66 XP_011531890 (OMIM: 605515,613670) PREDICTED: fork ( 577) 2175 253.2 2e-66 NP_001231742 (OMIM: 605515,613670) forkhead box pr ( 577) 2175 253.2 2e-66 NP_055306 (OMIM: 602081,605317) forkhead box prote ( 715) 2176 253.3 2.3e-66 NP_683696 (OMIM: 602081,605317) forkhead box prote ( 740) 2176 253.4 2.3e-66 XP_016868290 (OMIM: 602081,605317) PREDICTED: fork ( 740) 2176 253.4 2.3e-66 NP_001166237 (OMIM: 602081,605317) forkhead box pr ( 714) 2166 252.2 4.8e-66 NP_612466 (OMIM: 608924) forkhead box protein P4 i ( 667) 2107 245.7 4.2e-64 NP_001231739 (OMIM: 605515,613670) forkhead box pr ( 693) 2032 237.5 1.3e-61 NP_001231741 (OMIM: 605515,613670) forkhead box pr ( 601) 1929 226.1 3.1e-58 NP_683697 (OMIM: 602081,605317) forkhead box prote ( 432) 1129 137.8 8.4e-32 NP_001166238 (OMIM: 602081,605317) forkhead box pr ( 457) 1129 137.8 8.8e-32 NP_001107849 (OMIM: 222100,300292,304790) forkhead ( 396) 500 68.4 5.9e-11 NP_054728 (OMIM: 222100,300292,304790) forkhead bo ( 431) 500 68.4 6.3e-11 XP_006724596 (OMIM: 222100,300292,304790) PREDICTE ( 454) 500 68.4 6.6e-11 XP_016885055 (OMIM: 222100,300292,304790) PREDICTE ( 504) 500 68.5 7.1e-11 XP_016885054 (OMIM: 222100,300292,304790) PREDICTE ( 516) 500 68.5 7.3e-11 NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 328 49.4 2.7e-05 NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 313 47.8 9.9e-05 NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 312 47.8 0.00015 NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 311 47.7 0.00018 XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 308 47.3 0.00019 NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 308 47.3 0.00019 >>NP_001012426 (OMIM: 608924) forkhead box protein P4 is (680 aa) initn: 4570 init1: 4570 opt: 4570 Z-score: 2739.3 bits: 517.3 E(85289): 7.6e-146 Smith-Waterman score: 4570; 100.0% identity (100.0% similar) in 680 aa overlap (1-680:1-680) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 ERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 PLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 LETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 REYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 LPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPS 610 620 630 640 650 660 670 680 pF1KB6 ASGPPEDRDLEEELPGEELS :::::::::::::::::::: NP_001 ASGPPEDRDLEEELPGEELS 670 680 >>XP_006715054 (OMIM: 608924) PREDICTED: forkhead box pr (679 aa) initn: 3190 init1: 3190 opt: 4553 Z-score: 2729.2 bits: 515.4 E(85289): 2.8e-145 Smith-Waterman score: 4553; 99.9% identity (99.9% similar) in 680 aa overlap (1-680:1-679) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQP :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_006 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQA-VCPTDLPQLWKGEGAPGQP 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 AEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKES 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 ERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 PLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAI 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 LETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 REYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSL 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB6 LPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPS 600 610 620 630 640 650 670 680 pF1KB6 ASGPPEDRDLEEELPGEELS :::::::::::::::::::: XP_006 ASGPPEDRDLEEELPGEELS 660 670 >>XP_011512591 (OMIM: 608924) PREDICTED: forkhead box pr (687 aa) initn: 3195 init1: 3195 opt: 4546 Z-score: 2725.0 bits: 514.6 E(85289): 4.8e-145 Smith-Waterman score: 4546; 99.0% identity (99.0% similar) in 687 aa overlap (1-680:1-687) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQA-------AVCPTDLPQLWKG :::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_011 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQASPVSPTAAVCPTDLPQLWKG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP 610 620 630 640 650 660 660 670 680 pF1KB6 LGAPNPSASGPPEDRDLEEELPGEELS ::::::::::::::::::::::::::: XP_011 LGAPNPSASGPPEDRDLEEELPGEELS 670 680 >>XP_016865722 (OMIM: 608924) PREDICTED: forkhead box pr (687 aa) initn: 3195 init1: 3195 opt: 4546 Z-score: 2725.0 bits: 514.6 E(85289): 4.8e-145 Smith-Waterman score: 4546; 99.0% identity (99.0% similar) in 687 aa overlap (1-680:1-687) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQA-------AVCPTDLPQLWKG :::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_016 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQASPVSPTAAVCPTDLPQLWKG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP 610 620 630 640 650 660 660 670 680 pF1KB6 LGAPNPSASGPPEDRDLEEELPGEELS ::::::::::::::::::::::::::: XP_016 LGAPNPSASGPPEDRDLEEELPGEELS 670 680 >>NP_001012427 (OMIM: 608924) forkhead box protein P4 is (678 aa) initn: 3683 init1: 3683 opt: 4544 Z-score: 2723.9 bits: 514.4 E(85289): 5.5e-145 Smith-Waterman score: 4544; 99.7% identity (99.7% similar) in 680 aa overlap (1-680:1-678) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::: :::::::::::::::::::::::::::::::::::::: NP_001 ILSPPQLQALLQQQQALMLQ--QEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 AEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKES 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 ERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB6 PLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAI 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB6 LETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB6 REYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSL 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB6 LPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPS 600 610 620 630 640 650 670 680 pF1KB6 ASGPPEDRDLEEELPGEELS :::::::::::::::::::: NP_001 ASGPPEDRDLEEELPGEELS 660 670 >>XP_011512592 (OMIM: 608924) PREDICTED: forkhead box pr (685 aa) initn: 4075 init1: 3172 opt: 4520 Z-score: 2709.5 bits: 511.8 E(85289): 3.5e-144 Smith-Waterman score: 4520; 98.7% identity (98.7% similar) in 687 aa overlap (1-680:1-685) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::: :::::::::::::::::::::::::::::::::::::: XP_011 ILSPPQLQALLQQQQALMLQ--QEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 130 140 150 160 170 190 200 210 220 230 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQA-------AVCPTDLPQLWKG :::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_011 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQASPVSPTAAVCPTDLPQLWKG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB6 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB6 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB6 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP 600 610 620 630 640 650 660 670 680 pF1KB6 LGAPNPSASGPPEDRDLEEELPGEELS ::::::::::::::::::::::::::: XP_011 LGAPNPSASGPPEDRDLEEELPGEELS 660 670 680 >>XP_016865723 (OMIM: 608924) PREDICTED: forkhead box pr (649 aa) initn: 2855 init1: 2855 opt: 4206 Z-score: 2522.8 bits: 477.1 E(85289): 8.8e-134 Smith-Waterman score: 4206; 98.9% identity (98.9% similar) in 638 aa overlap (1-631:1-638) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQA-------AVCPTDLPQLWKG :::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_016 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQASPVSPTAAVCPTDLPQLWKG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP :::::::::::::::::::::::::::::::::::::: XP_016 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYRAVSAPGPAFL 610 620 630 640 660 670 680 pF1KB6 LGAPNPSASGPPEDRDLEEELPGEELS >>XP_011512594 (OMIM: 608924) PREDICTED: forkhead box pr (655 aa) initn: 3612 init1: 3195 opt: 3926 Z-score: 2355.9 bits: 446.3 E(85289): 1.7e-124 Smith-Waterman score: 4276; 94.3% identity (94.3% similar) in 687 aa overlap (1-680:1-655) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::: :::::::::::::::::::: XP_011 LLHFQQQQ--------------------------------VPVSVAMMSPQMLTPQQMQQ 70 80 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 90 100 110 120 130 140 190 200 210 220 230 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQA-------AVCPTDLPQLWKG :::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_011 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQASPVSPTAAVCPTDLPQLWKG 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB6 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB6 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB6 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA 390 400 410 420 430 440 480 490 500 510 520 530 pF1KB6 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG 450 460 470 480 490 500 540 550 560 570 580 590 pF1KB6 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN 510 520 530 540 550 560 600 610 620 630 640 650 pF1KB6 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP 570 580 590 600 610 620 660 670 680 pF1KB6 LGAPNPSASGPPEDRDLEEELPGEELS ::::::::::::::::::::::::::: XP_011 LGAPNPSASGPPEDRDLEEELPGEELS 630 640 650 >>XP_011512595 (OMIM: 608924) PREDICTED: forkhead box pr (581 aa) initn: 3195 init1: 3195 opt: 3884 Z-score: 2331.6 bits: 441.6 E(85289): 3.9e-123 Smith-Waterman score: 3884; 98.8% identity (98.8% similar) in 581 aa overlap (107-680:1-581) 80 90 100 110 120 130 pF1KB6 LLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQILSPPQLQALLQQQQA :::::::::::::::::::::::::::::: XP_011 MMSPQMLTPQQMQQILSPPQLQALLQQQQA 10 20 30 140 150 160 170 180 190 pF1KB6 LMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQQQLLQMQQLQQQHLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQQQLLQMQQLQQQHLLN 40 50 60 70 80 90 200 210 220 230 240 pF1KB6 LQRQGLVSLQPNQASGPLQTLPQA-------AVCPTDLPQLWKGEGAPGQPAEDSVKQEG :::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_011 LQRQGLVSLQPNQASGPLQTLPQASPVSPTAAVCPTDLPQLWKGEGAPGQPAEDSVKQEG 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB6 LDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGSHPLYGHGEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGSHPLYGHGEC 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 KWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAMMAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAMMAH 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB6 LHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVTPLRPPGLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVTPLRPPGLGS 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB6 ASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLT 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB6 LNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEREYQKRRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEREYQKRRPP 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB6 KMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSLLPLSHDDVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSLLPLSHDDVG 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB6 APVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPSASGPPEDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPSASGPPEDRD 520 530 540 550 560 570 670 680 pF1KB6 LEEELPGEELS ::::::::::: XP_011 LEEELPGEELS 580 >>XP_011512593 (OMIM: 608924) PREDICTED: forkhead box pr (675 aa) initn: 3337 init1: 1938 opt: 3335 Z-score: 2003.5 bits: 381.1 E(85289): 7.4e-105 Smith-Waterman score: 4433; 97.2% identity (97.2% similar) in 687 aa overlap (1-680:1-675) 10 20 30 40 50 60 pF1KB6 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQA-------AVCPTDLPQLWKG :::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_011 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQASPVSPTAAVCPTDLPQLWKG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 IQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPT :::::::::::::::::::::::::::::: :::::::::::::::::: XP_011 IQLAKESERLQAMMAHLHMRPSEPKPFSQP------------VTVSAADSFPDGLVHPPT 370 380 390 400 420 430 440 450 460 470 pF1KB6 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAAAPVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYA 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB6 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKG 470 480 490 500 510 520 540 550 560 570 580 590 pF1KB6 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN 530 540 550 560 570 580 600 610 620 630 640 650 pF1KB6 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPP 590 600 610 620 630 640 660 670 680 pF1KB6 LGAPNPSASGPPEDRDLEEELPGEELS ::::::::::::::::::::::::::: XP_011 LGAPNPSASGPPEDRDLEEELPGEELS 650 660 670 680 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:27:06 2016 done: Sat Nov 5 14:27:08 2016 Total Scan time: 14.410 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]