FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6272, 773 aa 1>>>pF1KB6272 773 - 773 aa - 773 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3335+/-0.00101; mu= 3.5249+/- 0.061 mean_var=234.2382+/-48.024, 0's: 0 Z-trim(113.3): 38 B-trim: 603 in 1/49 Lambda= 0.083800 statistics sampled from 13897 (13929) to 13897 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.428), width: 16 Scan time: 4.730 The best scores are: opt bits E(32554) CCDS58631.1 TCF4 gene_id:6925|Hs108|chr18 ( 773) 5269 650.3 3.3e-186 CCDS42438.1 TCF4 gene_id:6925|Hs108|chr18 ( 671) 4559 564.4 2.1e-160 CCDS82257.1 TCF4 gene_id:6925|Hs108|chr18 ( 670) 4542 562.4 8.5e-160 CCDS58630.1 TCF4 gene_id:6925|Hs108|chr18 ( 677) 4537 561.8 1.3e-159 CCDS11960.1 TCF4 gene_id:6925|Hs108|chr18 ( 667) 4517 559.4 6.9e-159 CCDS58629.1 TCF4 gene_id:6925|Hs108|chr18 ( 647) 4402 545.5 1e-154 CCDS77192.1 TCF4 gene_id:6925|Hs108|chr18 ( 643) 4360 540.4 3.5e-153 CCDS59321.1 TCF4 gene_id:6925|Hs108|chr18 ( 664) 4349 539.1 8.9e-153 CCDS58628.1 TCF4 gene_id:6925|Hs108|chr18 ( 625) 4192 520.1 4.4e-147 CCDS58627.1 TCF4 gene_id:6925|Hs108|chr18 ( 600) 3832 476.5 5.4e-134 CCDS77191.1 TCF4 gene_id:6925|Hs108|chr18 ( 596) 3790 471.4 1.8e-132 CCDS82255.1 TCF4 gene_id:6925|Hs108|chr18 ( 541) 3659 455.6 9.9e-128 CCDS58626.1 TCF4 gene_id:6925|Hs108|chr18 ( 537) 3617 450.5 3.3e-126 CCDS58624.1 TCF4 gene_id:6925|Hs108|chr18 ( 511) 3295 411.5 1.7e-114 CCDS58625.1 TCF4 gene_id:6925|Hs108|chr18 ( 507) 3253 406.5 5.6e-113 CCDS58623.1 TCF4 gene_id:6925|Hs108|chr18 ( 507) 3252 406.3 6.1e-113 CCDS10159.1 TCF12 gene_id:6938|Hs108|chr15 ( 682) 2782 349.6 9.8e-96 CCDS42042.1 TCF12 gene_id:6938|Hs108|chr15 ( 512) 2088 265.6 1.4e-70 CCDS76761.1 TCF12 gene_id:6938|Hs108|chr15 ( 446) 1728 222.1 1.6e-57 CCDS10160.1 TCF12 gene_id:6938|Hs108|chr15 ( 706) 1241 163.3 1.2e-39 CCDS76760.1 TCF12 gene_id:6938|Hs108|chr15 ( 536) 1216 160.2 8e-39 CCDS12074.1 TCF3 gene_id:6929|Hs108|chr19 ( 654) 744 103.2 1.4e-21 CCDS45899.1 TCF3 gene_id:6929|Hs108|chr19 ( 651) 654 92.3 2.6e-18 >>CCDS58631.1 TCF4 gene_id:6925|Hs108|chr18 (773 aa) initn: 5269 init1: 5269 opt: 5269 Z-score: 3456.5 bits: 650.3 E(32554): 3.3e-186 Smith-Waterman score: 5269; 100.0% identity (100.0% similar) in 773 aa overlap (1-773:1-773) 10 20 30 40 50 60 pF1KB6 MFSKRLEKIPQVPLLFPFIFIILTNYSKMEGAVESQPSFFKTSQDIVTCTWVENCYSSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MFSKRLEKIPQVPLLFPFIFIILTNYSKMEGAVESQPSFFKTSQDIVTCTWVENCYSSFS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RRPLEQMFCKHQSKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RRPLEQMFCKHQSKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 HMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 PHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 QTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 LHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 TGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 PGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 PEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVI 670 680 690 700 710 720 730 740 750 760 770 pF1KB6 LSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 730 740 750 760 770 >>CCDS42438.1 TCF4 gene_id:6925|Hs108|chr18 (671 aa) initn: 4559 init1: 4559 opt: 4559 Z-score: 2993.4 bits: 564.4 E(32554): 2.1e-160 Smith-Waterman score: 4559; 100.0% identity (100.0% similar) in 671 aa overlap (103-773:1-671) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: CCDS42 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 580 590 600 610 620 630 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: CCDS42 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 640 650 660 670 >>CCDS82257.1 TCF4 gene_id:6925|Hs108|chr18 (670 aa) initn: 2455 init1: 2455 opt: 4542 Z-score: 2982.3 bits: 562.4 E(32554): 8.5e-160 Smith-Waterman score: 4542; 99.9% identity (99.9% similar) in 671 aa overlap (103-773:1-670) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: CCDS82 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: CCDS82 IYSPDHTNNSFSSNPSTPVGSPPSLS-GTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 390 400 410 420 430 440 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 450 460 470 480 490 500 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR 510 520 530 540 550 560 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 570 580 590 600 610 620 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: CCDS82 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 630 640 650 660 670 >>CCDS58630.1 TCF4 gene_id:6925|Hs108|chr18 (677 aa) initn: 3297 init1: 3297 opt: 4537 Z-score: 2979.0 bits: 561.8 E(32554): 1.3e-159 Smith-Waterman score: 4537; 99.1% identity (99.1% similar) in 677 aa overlap (103-773:1-677) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: CCDS58 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSS------VYAPSASTADYNRDSPGYPSS ::::::::::::::::::::::::::::::::: ::::::::::::::::::::: CCDS58 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSLVLSPQVYAPSASTADYNRDSPGYPSS 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 KPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLS 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB6 YPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDAL 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB6 GKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQS 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB6 RIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSA 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB6 NRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQ 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB6 SVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAE 520 530 540 550 560 570 670 680 690 700 710 720 pF1KB6 REKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 REKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQ 580 590 600 610 620 630 730 740 750 760 770 pF1KB6 VRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 640 650 660 670 >>CCDS11960.1 TCF4 gene_id:6925|Hs108|chr18 (667 aa) initn: 3747 init1: 3747 opt: 4517 Z-score: 2966.0 bits: 559.4 E(32554): 6.9e-159 Smith-Waterman score: 4517; 99.4% identity (99.4% similar) in 671 aa overlap (103-773:1-667) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: CCDS11 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: CCDS11 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSIT----SNNDDEDLTPEQKAEREKERR 520 530 540 550 560 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 570 580 590 600 610 620 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: CCDS11 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 630 640 650 660 >>CCDS58629.1 TCF4 gene_id:6925|Hs108|chr18 (647 aa) initn: 4402 init1: 4402 opt: 4402 Z-score: 2891.1 bits: 545.5 E(32554): 1e-154 Smith-Waterman score: 4402; 100.0% identity (100.0% similar) in 647 aa overlap (127-773:1-647) 100 110 120 130 140 150 pF1KB6 LCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRS :::::::::::::::::::::::::::::: CCDS58 MFSPPVSSGKNGPTSLASGHFTGSNVEDRS 10 20 30 160 170 180 190 200 210 pF1KB6 SSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGR 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB6 ESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVR 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB6 KVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMN 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB6 QPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTS 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB6 SCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPS 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB6 LSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGG 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB6 HGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPV 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB6 PQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKL 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB6 DDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRM 520 530 540 550 560 570 700 710 720 730 740 750 pF1KB6 VQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSL 580 590 600 610 620 630 760 770 pF1KB6 AGPHPGMGDASNHMGQM ::::::::::::::::: CCDS58 AGPHPGMGDASNHMGQM 640 >>CCDS77192.1 TCF4 gene_id:6925|Hs108|chr18 (643 aa) initn: 3590 init1: 3590 opt: 4360 Z-score: 2863.7 bits: 540.4 E(32554): 3.5e-153 Smith-Waterman score: 4360; 99.4% identity (99.4% similar) in 647 aa overlap (127-773:1-643) 100 110 120 130 140 150 pF1KB6 LCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRS :::::::::::::::::::::::::::::: CCDS77 MFSPPVSSGKNGPTSLASGHFTGSNVEDRS 10 20 30 160 170 180 190 200 210 pF1KB6 SSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGR 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB6 ESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVR 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB6 KVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMN 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB6 QPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTS 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB6 SCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPS 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB6 LSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGG 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB6 HGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 HGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPV 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB6 PQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKL 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB6 DDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRM ::::::::::: ::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DDDKKDIKSIT----SNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRM 520 530 540 550 560 700 710 720 730 740 750 pF1KB6 VQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSL 570 580 590 600 610 620 760 770 pF1KB6 AGPHPGMGDASNHMGQM ::::::::::::::::: CCDS77 AGPHPGMGDASNHMGQM 630 640 >>CCDS59321.1 TCF4 gene_id:6925|Hs108|chr18 (664 aa) initn: 3091 init1: 2298 opt: 4349 Z-score: 2856.3 bits: 539.1 E(32554): 8.9e-153 Smith-Waterman score: 4349; 98.2% identity (98.6% similar) in 656 aa overlap (118-773:14-664) 90 100 110 120 130 140 pF1KB6 NPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHF ..: : . ::::::::::::::::::::: CCDS59 MQRAKTELFRLQIVTDDLRKNEMFSPPVSSGKNGPTSLASGHF 10 20 30 40 150 160 170 180 190 200 pF1KB6 TGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTE 50 60 70 80 90 100 210 220 230 240 250 260 pF1KB6 RGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 RGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSA 110 120 130 140 150 160 270 280 290 300 310 320 pF1KB6 MEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSD 170 180 190 200 210 220 330 340 350 360 370 380 pF1KB6 PWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHR 230 240 250 260 270 280 390 400 410 420 430 440 pF1KB6 SGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNP 290 300 310 320 330 340 450 460 470 480 490 500 pF1KB6 STPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 STPVGSPPSLS-GTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAV 350 360 370 380 390 400 510 520 530 540 550 560 pF1KB6 GPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSH 410 420 430 440 450 460 570 580 590 600 610 620 pF1KB6 SLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQD 470 480 490 500 510 520 630 640 650 660 670 680 pF1KB6 TKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDIN :::::::::::::::::::: :::::::::::::::::::::::::::::::::::: CCDS59 TKSSEDKKLDDDKKDIKSIT----SNNDDEDLTPEQKAEREKERRMANNARERLRVRDIN 530 540 550 560 570 690 700 710 720 730 740 pF1KB6 EAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKV 580 590 600 610 620 630 750 760 770 pF1KB6 SSEPPPLSLAGPHPGMGDASNHMGQM :::::::::::::::::::::::::: CCDS59 SSEPPPLSLAGPHPGMGDASNHMGQM 640 650 660 >>CCDS58628.1 TCF4 gene_id:6925|Hs108|chr18 (625 aa) initn: 3422 init1: 3422 opt: 4192 Z-score: 2754.1 bits: 520.1 E(32554): 4.4e-147 Smith-Waterman score: 4192; 99.2% identity (99.4% similar) in 623 aa overlap (151-773:7-625) 130 140 150 160 170 180 pF1KB6 LLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYD .::::::::::::::::::::::::::::: CCDS58 MEEDSRDVEDRSSSGSWGNGGHPSPSRNYGDGTPYD 10 20 30 190 200 210 220 230 240 pF1KB6 HMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGT 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB6 LSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDS 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB6 PGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLH 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB6 PHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSS 220 230 240 250 260 270 430 440 450 460 470 480 pF1KB6 QTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGP 280 290 300 310 320 330 490 500 510 520 530 540 pF1KB6 LHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG 340 350 360 370 380 390 550 560 570 580 590 600 pF1KB6 TGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMP 400 410 420 430 440 450 610 620 630 640 650 660 pF1KB6 PGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLT ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: CCDS58 PGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSIT----SNNDDEDLT 460 470 480 490 500 510 670 680 690 700 710 720 pF1KB6 PEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVI 520 530 540 550 560 570 730 740 750 760 770 pF1KB6 LSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 580 590 600 610 620 >>CCDS58627.1 TCF4 gene_id:6925|Hs108|chr18 (600 aa) initn: 3706 init1: 3706 opt: 3832 Z-score: 2519.1 bits: 476.5 E(32554): 5.4e-134 Smith-Waterman score: 3832; 99.8% identity (99.8% similar) in 569 aa overlap (205-773:33-600) 180 190 200 210 220 230 pF1KB6 DGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMD ::::::::::::::::::::: :::::::: CCDS58 DIFFQFIIARVRKCYSLSCLHTLPVVPTLRKTERGSYSSYGRESNLQGCHQ-SLLGGDMD 10 20 30 40 50 60 240 250 260 270 280 290 pF1KB6 MGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTA 70 80 90 100 110 120 300 310 320 330 340 350 pF1KB6 DYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSS 130 140 150 160 170 180 360 370 380 390 400 410 pF1KB6 SYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGS 190 200 210 220 230 240 420 430 440 450 460 470 pF1KB6 GAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSS 250 260 270 280 290 300 480 490 500 510 520 530 pF1KB6 PNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGG 310 320 330 340 350 360 540 550 560 570 580 590 pF1KB6 LGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQD 370 380 390 400 410 420 600 610 620 630 640 650 pF1KB6 PYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNN 430 440 450 460 470 480 660 670 680 690 700 710 pF1KB6 DDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILH 490 500 510 520 530 540 720 730 740 750 760 770 pF1KB6 QAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 550 560 570 580 590 600 773 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:59:51 2016 done: Sat Nov 5 13:59:52 2016 Total Scan time: 4.730 Total Display time: 0.250 Function used was FASTA [36.3.4 Apr, 2011]