FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6272, 773 aa 1>>>pF1KB6272 773 - 773 aa - 773 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1917+/-0.000406; mu= 4.6100+/- 0.025 mean_var=269.6120+/-56.305, 0's: 0 Z-trim(121.1): 113 B-trim: 1913 in 1/52 Lambda= 0.078110 statistics sampled from 37175 (37290) to 37175 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.437), width: 16 Scan time: 13.020 The best scores are: opt bits E(85289) NP_001230155 (OMIM: 602272,610954,613267) transcri ( 773) 5269 607.6 6.5e-173 XP_006722600 (OMIM: 602272,610954,613267) PREDICTE ( 671) 4559 527.5 7.1e-149 XP_006722599 (OMIM: 602272,610954,613267) PREDICTE ( 671) 4559 527.5 7.1e-149 NP_001077431 (OMIM: 602272,610954,613267) transcri ( 671) 4559 527.5 7.1e-149 NP_001317533 (OMIM: 602272,610954,613267) transcri ( 670) 4542 525.6 2.7e-148 XP_005266798 (OMIM: 602272,610954,613267) PREDICTE ( 670) 4540 525.4 3.1e-148 XP_016881427 (OMIM: 602272,610954,613267) PREDICTE ( 670) 4540 525.4 3.1e-148 NP_001230157 (OMIM: 602272,610954,613267) transcri ( 677) 4537 525.0 4e-148 NP_003190 (OMIM: 602272,610954,613267) transcripti ( 667) 4517 522.8 1.9e-147 XP_016881430 (OMIM: 602272,610954,613267) PREDICTE ( 667) 4517 522.8 1.9e-147 XP_016881429 (OMIM: 602272,610954,613267) PREDICTE ( 667) 4517 522.8 1.9e-147 XP_016881432 (OMIM: 602272,610954,613267) PREDICTE ( 666) 4500 520.8 7.1e-147 XP_016881431 (OMIM: 602272,610954,613267) PREDICTE ( 666) 4498 520.6 8.3e-147 XP_011524460 (OMIM: 602272,610954,613267) PREDICTE ( 669) 4408 510.5 9.4e-144 XP_005266801 (OMIM: 602272,610954,613267) PREDICTE ( 647) 4402 509.8 1.5e-143 XP_005266800 (OMIM: 602272,610954,613267) PREDICTE ( 647) 4402 509.8 1.5e-143 XP_005266796 (OMIM: 602272,610954,613267) PREDICTE ( 647) 4402 509.8 1.5e-143 NP_001230156 (OMIM: 602272,610954,613267) transcri ( 647) 4402 509.8 1.5e-143 XP_016881424 (OMIM: 602272,610954,613267) PREDICTE ( 646) 4385 507.9 5.6e-143 XP_016881434 (OMIM: 602272,610954,613267) PREDICTE ( 646) 4385 507.9 5.6e-143 XP_016881433 (OMIM: 602272,610954,613267) PREDICTE ( 646) 4383 507.6 6.5e-143 XP_005266802 (OMIM: 602272,610954,613267) PREDICTE ( 646) 4383 507.6 6.5e-143 XP_016881423 (OMIM: 602272,610954,613267) PREDICTE ( 646) 4383 507.6 6.5e-143 XP_006722601 (OMIM: 602272,610954,613267) PREDICTE ( 646) 4383 507.6 6.5e-143 XP_016881436 (OMIM: 602272,610954,613267) PREDICTE ( 643) 4360 505.1 3.9e-142 NP_001293136 (OMIM: 602272,610954,613267) transcri ( 643) 4360 505.1 3.9e-142 XP_016881425 (OMIM: 602272,610954,613267) PREDICTE ( 643) 4360 505.1 3.9e-142 XP_016881435 (OMIM: 602272,610954,613267) PREDICTE ( 643) 4360 505.1 3.9e-142 NP_001230159 (OMIM: 602272,610954,613267) transcri ( 664) 4349 503.8 9.4e-142 XP_016881437 (OMIM: 602272,610954,613267) PREDICTE ( 642) 4341 502.9 1.7e-141 XP_016881438 (OMIM: 602272,610954,613267) PREDICTE ( 642) 4341 502.9 1.7e-141 XP_016881426 (OMIM: 602272,610954,613267) PREDICTE ( 642) 4341 502.9 1.7e-141 XP_016881439 (OMIM: 602272,610954,613267) PREDICTE ( 641) 4324 501.0 6.5e-141 XP_005266804 (OMIM: 602272,610954,613267) PREDICTE ( 629) 4234 490.8 7.2e-138 XP_016881440 (OMIM: 602272,610954,613267) PREDICTE ( 628) 4217 488.9 2.7e-137 NP_001230160 (OMIM: 602272,610954,613267) transcri ( 625) 4192 486.1 1.9e-136 XP_005266806 (OMIM: 602272,610954,613267) PREDICTE ( 601) 3851 447.7 6.9e-125 NP_001230161 (OMIM: 602272,610954,613267) transcri ( 600) 3832 445.5 3e-124 XP_016881441 (OMIM: 602272,610954,613267) PREDICTE ( 599) 3815 443.6 1.1e-123 XP_016881442 (OMIM: 602272,610954,613267) PREDICTE ( 597) 3809 442.9 1.8e-123 NP_001293137 (OMIM: 602272,610954,613267) transcri ( 596) 3790 440.8 8e-123 NP_001317534 (OMIM: 602272,610954,613267) transcri ( 541) 3659 426.0 2.1e-118 XP_005266812 (OMIM: 602272,610954,613267) PREDICTE ( 541) 3659 426.0 2.1e-118 XP_005266809 (OMIM: 602272,610954,613267) PREDICTE ( 541) 3659 426.0 2.1e-118 XP_011524462 (OMIM: 602272,610954,613267) PREDICTE ( 541) 3659 426.0 2.1e-118 XP_016881444 (OMIM: 602272,610954,613267) PREDICTE ( 540) 3642 424.1 7.8e-118 XP_016881443 (OMIM: 602272,610954,613267) PREDICTE ( 540) 3642 424.1 7.8e-118 NP_001230162 (OMIM: 602272,610954,613267) transcri ( 537) 3617 421.3 5.5e-117 XP_016881445 (OMIM: 602272,610954,613267) PREDICTE ( 537) 3617 421.3 5.5e-117 NP_001230163 (OMIM: 602272,610954,613267) transcri ( 511) 3295 384.9 4.4e-106 >>NP_001230155 (OMIM: 602272,610954,613267) transcriptio (773 aa) initn: 5269 init1: 5269 opt: 5269 Z-score: 3225.3 bits: 607.6 E(85289): 6.5e-173 Smith-Waterman score: 5269; 100.0% identity (100.0% similar) in 773 aa overlap (1-773:1-773) 10 20 30 40 50 60 pF1KB6 MFSKRLEKIPQVPLLFPFIFIILTNYSKMEGAVESQPSFFKTSQDIVTCTWVENCYSSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFSKRLEKIPQVPLLFPFIFIILTNYSKMEGAVESQPSFFKTSQDIVTCTWVENCYSSFS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RRPLEQMFCKHQSKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRPLEQMFCKHQSKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 HMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 PHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 QTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 LHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 TGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 PGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 PEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVI 670 680 690 700 710 720 730 740 750 760 770 pF1KB6 LSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 730 740 750 760 770 >>XP_006722600 (OMIM: 602272,610954,613267) PREDICTED: t (671 aa) initn: 4559 init1: 4559 opt: 4559 Z-score: 2793.7 bits: 527.5 E(85289): 7.1e-149 Smith-Waterman score: 4559; 100.0% identity (100.0% similar) in 671 aa overlap (103-773:1-671) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: XP_006 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 580 590 600 610 620 630 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: XP_006 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 640 650 660 670 >>XP_006722599 (OMIM: 602272,610954,613267) PREDICTED: t (671 aa) initn: 4559 init1: 4559 opt: 4559 Z-score: 2793.7 bits: 527.5 E(85289): 7.1e-149 Smith-Waterman score: 4559; 100.0% identity (100.0% similar) in 671 aa overlap (103-773:1-671) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: XP_006 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 580 590 600 610 620 630 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: XP_006 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 640 650 660 670 >>NP_001077431 (OMIM: 602272,610954,613267) transcriptio (671 aa) initn: 4559 init1: 4559 opt: 4559 Z-score: 2793.7 bits: 527.5 E(85289): 7.1e-149 Smith-Waterman score: 4559; 100.0% identity (100.0% similar) in 671 aa overlap (103-773:1-671) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: NP_001 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 580 590 600 610 620 630 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: NP_001 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 640 650 660 670 >>NP_001317533 (OMIM: 602272,610954,613267) transcriptio (670 aa) initn: 2455 init1: 2455 opt: 4542 Z-score: 2783.4 bits: 525.6 E(85289): 2.7e-148 Smith-Waterman score: 4542; 99.9% identity (99.9% similar) in 671 aa overlap (103-773:1-670) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: NP_001 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: NP_001 IYSPDHTNNSFSSNPSTPVGSPPSLS-GTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 390 400 410 420 430 440 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 450 460 470 480 490 500 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR 510 520 530 540 550 560 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 570 580 590 600 610 620 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: NP_001 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 630 640 650 660 670 >>XP_005266798 (OMIM: 602272,610954,613267) PREDICTED: t (670 aa) initn: 3706 init1: 3706 opt: 4540 Z-score: 2782.2 bits: 525.4 E(85289): 3.1e-148 Smith-Waterman score: 4540; 99.9% identity (99.9% similar) in 671 aa overlap (103-773:1-670) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: XP_005 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_005 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQ-SLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 210 220 230 240 250 260 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 270 280 290 300 310 320 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 330 340 350 360 370 380 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 390 400 410 420 430 440 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 450 460 470 480 490 500 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR 510 520 530 540 550 560 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 570 580 590 600 610 620 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: XP_005 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 630 640 650 660 670 >>XP_016881427 (OMIM: 602272,610954,613267) PREDICTED: t (670 aa) initn: 3706 init1: 3706 opt: 4540 Z-score: 2782.2 bits: 525.4 E(85289): 3.1e-148 Smith-Waterman score: 4540; 99.9% identity (99.9% similar) in 671 aa overlap (103-773:1-670) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: XP_016 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_016 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQ-SLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 210 220 230 240 250 260 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 270 280 290 300 310 320 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 330 340 350 360 370 380 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 390 400 410 420 430 440 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 450 460 470 480 490 500 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR 510 520 530 540 550 560 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 570 580 590 600 610 620 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: XP_016 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 630 640 650 660 670 >>NP_001230157 (OMIM: 602272,610954,613267) transcriptio (677 aa) initn: 3297 init1: 3297 opt: 4537 Z-score: 2780.3 bits: 525.0 E(85289): 4e-148 Smith-Waterman score: 4537; 99.1% identity (99.1% similar) in 677 aa overlap (103-773:1-677) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: NP_001 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSS------VYAPSASTADYNRDSPGYPSS ::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_001 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSLVLSPQVYAPSASTADYNRDSPGYPSS 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 KPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLS 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB6 YPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDAL 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB6 GKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQS 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB6 RIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSA 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB6 NRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQ 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB6 SVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAE 520 530 540 550 560 570 670 680 690 700 710 720 pF1KB6 REKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQ 580 590 600 610 620 630 730 740 750 760 770 pF1KB6 VRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 640 650 660 670 >>NP_003190 (OMIM: 602272,610954,613267) transcription f (667 aa) initn: 3747 init1: 3747 opt: 4517 Z-score: 2768.2 bits: 522.8 E(85289): 1.9e-147 Smith-Waterman score: 4517; 99.4% identity (99.4% similar) in 671 aa overlap (103-773:1-667) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: NP_003 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_003 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSIT----SNNDDEDLTPEQKAEREKERR 520 530 540 550 560 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 570 580 590 600 610 620 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: NP_003 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 630 640 650 660 >>XP_016881430 (OMIM: 602272,610954,613267) PREDICTED: t (667 aa) initn: 3747 init1: 3747 opt: 4517 Z-score: 2768.2 bits: 522.8 E(85289): 1.9e-147 Smith-Waterman score: 4517; 99.4% identity (99.4% similar) in 671 aa overlap (103-773:1-667) 80 90 100 110 120 130 pF1KB6 SKNIISWTGMVAHTCNPSTLGGQGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPV :::::::::::::::::::::::::::::: XP_016 MHHQQRMAALGTDKELSDLLDFSAMFSPPV 10 20 30 140 150 160 170 180 190 pF1KB6 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERR ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_016 SEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSIT----SNNDDEDLTPEQKAEREKERR 520 530 540 550 560 680 690 700 710 720 730 pF1KB6 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNL 570 580 590 600 610 620 740 750 760 770 pF1KB6 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM ::::::::::::::::::::::::::::::::::::::::: XP_016 NPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM 630 640 650 660 773 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:59:52 2016 done: Sat Nov 5 13:59:54 2016 Total Scan time: 13.020 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]