FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6285, 862 aa 1>>>pF1KB6285 862 - 862 aa - 862 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9966+/-0.00113; mu= -0.7925+/- 0.068 mean_var=209.8332+/-43.165, 0's: 0 Z-trim(109.7): 54 B-trim: 338 in 2/51 Lambda= 0.088540 statistics sampled from 11046 (11091) to 11046 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.341), width: 16 Scan time: 4.810 The best scores are: opt bits E(32554) CCDS42421.1 TAF4B gene_id:6875|Hs108|chr18 ( 862) 5409 704.3 2.4e-202 CCDS77170.1 TAF4B gene_id:6875|Hs108|chr18 ( 867) 5389 701.7 1.4e-201 CCDS33500.1 TAF4 gene_id:6874|Hs108|chr20 (1085) 1210 168.0 8.4e-41 >>CCDS42421.1 TAF4B gene_id:6875|Hs108|chr18 (862 aa) initn: 5409 init1: 5409 opt: 5409 Z-score: 3746.3 bits: 704.3 E(32554): 2.4e-202 Smith-Waterman score: 5409; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862) 10 20 30 40 50 60 pF1KB6 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 AENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 TGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAIC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 LPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 KQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQKN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 RIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFLFIGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFLFIGAL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 QKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENYILCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENYILCS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 DTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB6 IQHRDANLTALAAIGPRKKRPLESGIEGLKDNLLASGTSSLTATKQLHRPRITRICLRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IQHRDANLTALAAIGPRKKRPLESGIEGLKDNLLASGTSSLTATKQLHRPRITRICLRDL 790 800 810 820 830 840 850 860 pF1KB6 IFCMEQEREMKYSRALYLALLK :::::::::::::::::::::: CCDS42 IFCMEQEREMKYSRALYLALLK 850 860 >>CCDS77170.1 TAF4B gene_id:6875|Hs108|chr18 (867 aa) initn: 5395 init1: 3306 opt: 5389 Z-score: 3732.5 bits: 701.7 E(32554): 1.4e-201 Smith-Waterman score: 5389; 99.4% identity (99.4% similar) in 867 aa overlap (1-862:1-867) 10 20 30 40 50 60 pF1KB6 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 TGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAIC 430 440 450 460 470 480 490 500 510 520 530 pF1KB6 LPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQL-----VVQQP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::: CCDS77 LPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLFSLFQVVQQP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 SGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQAS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 PTQKNRIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PTQKNRIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB6 FIGALQKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FIGALQKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASEN 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB6 YILCSDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YILCSDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQ 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB6 LELAQIQHRDANLTALAAIGPRKKRPLESGIEGLKDNLLASGTSSLTATKQLHRPRITRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LELAQIQHRDANLTALAAIGPRKKRPLESGIEGLKDNLLASGTSSLTATKQLHRPRITRI 790 800 810 820 830 840 840 850 860 pF1KB6 CLRDLIFCMEQEREMKYSRALYLALLK ::::::::::::::::::::::::::: CCDS77 CLRDLIFCMEQEREMKYSRALYLALLK 850 860 >>CCDS33500.1 TAF4 gene_id:6874|Hs108|chr20 (1085 aa) initn: 1595 init1: 895 opt: 1210 Z-score: 846.0 bits: 168.0 E(32554): 8.4e-41 Smith-Waterman score: 1624; 40.5% identity (61.8% similar) in 878 aa overlap (2-862:356-1085) 10 20 30 pF1KB6 MPAGLTEPAGAAPPAAVSASGTVTMAPAGAL ::. : .:. ::...:: .. . ::: CCDS33 SGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQT--LAASGPASTAASMVIGPTMQGAL 330 340 350 360 370 380 40 50 60 70 80 90 pF1KB6 PVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAP : . : : :. : : .. : : :.:..: :. .. : : . :::: : CCDS33 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLS-RTPTAT--TSGIRATLTPTVLA-PRLPQP 390 400 410 420 430 100 110 120 130 140 pF1KB6 QIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTR------AETTSNIT : :.:: :.::::: ::..:..: :... :::.... :. .... CCDS33 P------QNPTNIQ---NFQLPPGMVLVRSENGQLLMI-PQQALAQMQAQAHAQPQTTMA 440 450 460 470 480 150 160 170 180 190 200 pF1KB6 SRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPT :::.:.. :.: :: .. .: . ::: ::.. : :..:... :. CCDS33 PRPATPTSAPPVQISTVQAPGTPIIAR-QVTP--------TTIIKQV---SQAQTTVQPS 490 500 510 520 530 210 220 230 240 250 260 pF1KB6 SVVTVTPG-KP-LNTVTTLKPSSLG-ASSTPSNEPNLKAENSAAVQINLSPTMLENVKKC ... .:: .: : . . .::: :... .. :. . ...... . :: :::::: CCDS33 ATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETM-ENVKKC 540 550 560 570 580 590 270 280 290 300 310 320 pF1KB6 KNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPF ::::. ::::: ::.:: : . :::.::..:::.:::::.:: .:: ::.:::::.:::: CCDS33 KNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPF 600 610 620 630 640 650 330 340 350 360 370 380 pF1KB6 LKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIV ::.:. ::::: :.: .:::: :: :: :. :. :....:. . .. . : CCDS33 LKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQAT---TALTAVVLSSSVQRTAGKTAATV 660 670 680 690 700 710 390 400 410 420 430 440 pF1KB6 SGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVA ..: : ..: :. : : .:.: ::: . CCDS33 TSALQPPVLS------LTQP---------------------TQVGVGKQGQPTPLVIQ-- 720 730 740 450 460 470 480 490 500 pF1KB6 NTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT :: :: :: : :.: : .. :... CCDS33 --------QPPKP--------------------GALIRPPQV--------TLTQTPMVA- 750 760 510 520 530 540 550 560 pF1KB6 PVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTM : :: . . :: .:.. : :: CCDS33 -----LRQPHNRIMLTT--PQQIQLNPL---QP--------------------------- 770 780 790 570 580 590 600 610 pF1KB6 PVNTIIPTSQFPPASILKQITLPGNKILSL---QASPTQKNRIKENVTSCFRDEDDINDV .: ..: .:::.: :: ::. .:::..:: . :::.:::::: CCDS33 -----VP--------VVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDV 800 810 820 830 620 630 640 650 660 670 pF1KB6 TSMAGVNLNEENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSD .:::::::.::.: :::::::::::: .::::: ::. . ::.:::.::::: ::::. : CCDS33 ASMAGVNLSEESARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPD 840 850 860 870 880 890 680 690 700 710 720 730 pF1KB6 AVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENYILCSDTRSQLKFLEKLDQLEKQR .:. .:.:::.::..:.::.. ::.. .:: .. : ::.:.::::.:.:::.:::: CCDS33 VVSYVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQR 900 910 920 930 940 950 740 750 760 770 780 790 pF1KB6 KDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQIQHRDANLTALAAIGPRKK :: .:::.:..:::::: .::::::::::::::.:: ::::...:::::::::::::::: CCDS33 KDEQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKK 960 970 980 990 1000 1010 800 810 820 830 840 850 pF1KB6 RPLE-----SGIEGLKDNLLASGTSSLTATKQLHRPRITRICLRDLIFCMEQEREMKYSR : .. :: :: . .. :.:.. . .:. : ::::. :::::::.:.::: ..: CCDS33 RKVDCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQRITRVNLRDLIFCLENERETSHSL 1020 1030 1040 1050 1060 1070 860 pF1KB6 ALYLALLK :: :.:: CCDS33 LLYKAFLK 1080 862 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:32:48 2016 done: Sat Nov 5 14:32:49 2016 Total Scan time: 4.810 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]