FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6289, 763 aa 1>>>pF1KB6289 763 - 763 aa - 763 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9179+/-0.000379; mu= -1.2152+/- 0.024 mean_var=243.1201+/-50.168, 0's: 0 Z-trim(121.0): 146 B-trim: 585 in 1/57 Lambda= 0.082255 statistics sampled from 36936 (37083) to 36936 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.435), width: 16 Scan time: 13.710 The best scores are: opt bits E(85289) NP_068772 (OMIM: 602341) forkhead box protein M1 i ( 763) 5143 623.8 8e-178 XP_005253733 (OMIM: 602341) PREDICTED: forkhead bo ( 764) 5131 622.4 2.1e-177 XP_011519232 (OMIM: 602341) PREDICTED: forkhead bo ( 763) 5114 620.4 8.7e-177 NP_001230017 (OMIM: 602341) forkhead box protein M ( 748) 2845 351.1 9.7e-96 XP_011519233 (OMIM: 602341) PREDICTED: forkhead bo ( 749) 2845 351.1 9.7e-96 XP_011519235 (OMIM: 602341) PREDICTED: forkhead bo ( 437) 2838 350.2 1.1e-95 NP_001230018 (OMIM: 602341) forkhead box protein M ( 747) 2842 350.8 1.2e-95 NP_973732 (OMIM: 602341) forkhead box protein M1 i ( 748) 2842 350.8 1.2e-95 NP_973731 (OMIM: 602341) forkhead box protein M1 i ( 801) 2837 350.2 2e-95 XP_011519234 (OMIM: 602341) PREDICTED: forkhead bo ( 438) 2826 348.7 3e-95 XP_011519236 (OMIM: 602341) PREDICTED: forkhead bo ( 433) 2307 287.1 1e-76 XP_011519237 (OMIM: 602341) PREDICTED: forkhead bo ( 422) 2216 276.3 1.8e-73 XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 310 50.2 2.8e-05 NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 310 50.2 2.9e-05 XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 310 50.2 2.9e-05 XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 310 50.2 3e-05 XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 310 50.3 3e-05 NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 310 50.3 3e-05 NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 310 50.3 3e-05 NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 310 50.3 3e-05 XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 310 50.3 3.1e-05 NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 304 49.4 3.1e-05 XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 XP_016859448 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 XP_016859446 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 303 49.3 4e-05 XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 XP_005264340 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 303 49.3 4e-05 NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 284 47.1 0.00023 NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 278 46.3 0.00031 NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 277 46.3 0.00036 NP_001078940 (OMIM: 602628) forkhead box protein N ( 490) 277 46.3 0.00038 NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 274 45.9 0.00049 NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 272 45.7 0.00052 NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 273 45.8 0.00053 NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 269 45.3 0.00059 NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 269 45.3 0.00059 NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 267 45.0 0.00062 NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 269 45.3 0.00068 NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 269 45.3 0.00069 NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 269 45.3 0.00071 NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 267 45.0 0.00074 XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 267 45.1 0.00078 NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 266 44.9 0.00082 NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 267 45.1 0.00083 NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 263 44.5 0.0009 >>NP_068772 (OMIM: 602341) forkhead box protein M1 isofo (763 aa) initn: 5143 init1: 5143 opt: 5143 Z-score: 3313.5 bits: 623.8 E(85289): 8e-178 Smith-Waterman score: 5143; 100.0% identity (100.0% similar) in 763 aa overlap (1-763:1-763) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE 670 680 690 700 710 720 730 740 750 760 pF1KB6 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ ::::::::::::::::::::::::::::::::::::::::::: NP_068 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ 730 740 750 760 >>XP_005253733 (OMIM: 602341) PREDICTED: forkhead box pr (764 aa) initn: 2841 init1: 2841 opt: 5131 Z-score: 3305.8 bits: 622.4 E(85289): 2.1e-177 Smith-Waterman score: 5131; 99.9% identity (99.9% similar) in 764 aa overlap (1-763:1-764) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQ-KRPNPELRRNMTIKTEL :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_005 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQQKRPNPELRRNMTIKTEL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 PLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 APKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 ESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERR 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 ERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFK 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 TPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB6 STTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLT 670 680 690 700 710 720 720 730 740 750 760 pF1KB6 EGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ :::::::::::::::::::::::::::::::::::::::::::: XP_005 EGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ 730 740 750 760 >>XP_011519232 (OMIM: 602341) PREDICTED: forkhead box pr (763 aa) initn: 3759 init1: 3759 opt: 5114 Z-score: 3294.9 bits: 620.4 E(85289): 8.7e-177 Smith-Waterman score: 5114; 99.7% identity (99.7% similar) in 764 aa overlap (1-763:1-763) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_011 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETC-DGEAAGCTINNS 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQ-KRPNPELRRNMTIKTEL :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_011 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQQKRPNPELRRNMTIKTEL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 PLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRI 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB6 APKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKV 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB6 ESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB6 ERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFK 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 TPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDL 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB6 STTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLT 660 670 680 690 700 710 720 730 740 750 760 pF1KB6 EGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ :::::::::::::::::::::::::::::::::::::::::::: XP_011 EGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ 720 730 740 750 760 >>NP_001230017 (OMIM: 602341) forkhead box protein M1 is (748 aa) initn: 3944 init1: 2845 opt: 2845 Z-score: 1839.8 bits: 351.1 E(85289): 9.7e-96 Smith-Waterman score: 4978; 97.9% identity (98.0% similar) in 763 aa overlap (1-763:1-748) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETC-DGEAAGCTINNS 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP ::::::::::::::::::::::::: .:::::::::::::::::::: NP_001 ANGKVSFWTIHPSANRYLTLDQVFK--------------QQQKRPNPELRRNMTIKTELP 300 310 320 330 340 370 380 390 400 410 420 pF1KB6 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB6 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB6 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB6 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB6 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB6 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE 650 660 670 680 690 700 730 740 750 760 pF1KB6 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ ::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ 710 720 730 740 >>XP_011519233 (OMIM: 602341) PREDICTED: forkhead box pr (749 aa) initn: 2845 init1: 2845 opt: 2845 Z-score: 1839.8 bits: 351.1 E(85289): 9.7e-96 Smith-Waterman score: 4995; 98.0% identity (98.2% similar) in 763 aa overlap (1-763:1-749) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP ::::::::::::::::::::::::: .:::::::::::::::::::: XP_011 ANGKVSFWTIHPSANRYLTLDQVFK--------------QQQKRPNPELRRNMTIKTELP 310 320 330 340 370 380 390 400 410 420 pF1KB6 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB6 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB6 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB6 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB6 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB6 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE 650 660 670 680 690 700 730 740 750 760 pF1KB6 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ ::::::::::::::::::::::::::::::::::::::::::: XP_011 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ 710 720 730 740 >>XP_011519235 (OMIM: 602341) PREDICTED: forkhead box pr (437 aa) initn: 2868 init1: 2837 opt: 2838 Z-score: 1838.7 bits: 350.2 E(85289): 1.1e-95 Smith-Waterman score: 2838; 97.5% identity (98.9% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE :::. . .. .:.: XP_011 PKVFGEQVVFGYMSAAS 430 >>NP_001230018 (OMIM: 602341) forkhead box protein M1 is (747 aa) initn: 3941 init1: 2842 opt: 2842 Z-score: 1837.9 bits: 350.8 E(85289): 1.2e-95 Smith-Waterman score: 4976; 97.9% identity (97.9% similar) in 763 aa overlap (1-763:1-747) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETC-DGEAAGCTINNS 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP ::::::::::::::::::::::::: :::::::::::::::::::: NP_001 ANGKVSFWTIHPSANRYLTLDQVFK---------------QQKRPNPELRRNMTIKTELP 300 310 320 330 340 370 380 390 400 410 420 pF1KB6 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB6 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB6 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB6 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB6 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB6 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE 650 660 670 680 690 700 730 740 750 760 pF1KB6 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ ::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ 710 720 730 740 >>NP_973732 (OMIM: 602341) forkhead box protein M1 isofo (748 aa) initn: 2842 init1: 2842 opt: 2842 Z-score: 1837.9 bits: 350.8 E(85289): 1.2e-95 Smith-Waterman score: 4993; 98.0% identity (98.0% similar) in 763 aa overlap (1-763:1-748) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP ::::::::::::::::::::::::: :::::::::::::::::::: NP_973 ANGKVSFWTIHPSANRYLTLDQVFK---------------QQKRPNPELRRNMTIKTELP 310 320 330 340 370 380 390 400 410 420 pF1KB6 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB6 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 PKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVE 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB6 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 SPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB6 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 RSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKT 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB6 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 PIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLS 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB6 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 TTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTE 650 660 670 680 690 700 730 740 750 760 pF1KB6 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ ::::::::::::::::::::::::::::::::::::::::::: NP_973 GLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ 710 720 730 740 >>NP_973731 (OMIM: 602341) forkhead box protein M1 isofo (801 aa) initn: 2875 init1: 2837 opt: 2837 Z-score: 1834.2 bits: 350.2 E(85289): 2e-95 Smith-Waterman score: 5016; 95.2% identity (95.2% similar) in 795 aa overlap (1-757:1-795) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 LGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIA 370 380 390 400 410 420 430 440 pF1KB6 PKV--------------------------------------LLAEEGIAPLSSAGPGKEE ::: ::::::::::::::::::: NP_973 PKVFGEQVVFGYMSKFFSGDLRDFGTPITSLFNFIFLCLSVLLAEEGIAPLSSAGPGKEE 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB6 KLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVESPPLEEWPSPAPSFKEESSHSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 KLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVESPPLEEWPSPAPSFKEESSHSW 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB6 EDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRERSRSRRKQHLLPPCVDEPELLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 EDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRERSRSRRKQHLLPPCVDEPELLF 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB6 SEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKTPIKETLPISSTPSKSVLPRTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 SEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKTPIKETLPISSTPSKSVLPRTPE 610 620 630 640 650 660 630 640 650 660 670 680 pF1KB6 SWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLSTTPLQSAPPLESPQRLLSSEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 SWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLSTTPLQSAPPLESPQRLLSSEPL 670 680 690 700 710 720 690 700 710 720 730 740 pF1KB6 DLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTEGLVLDTMNDSLSKILLDISFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_973 DLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTEGLVLDTMNDSLSKILLDISFPG 730 740 750 760 770 780 750 760 pF1KB6 LDEDPLGPDNINWSQFIPELQ ::::::::::::::: NP_973 LDEDPLGPDNINWSQFIPELQ 790 800 >>XP_011519234 (OMIM: 602341) PREDICTED: forkhead box pr (438 aa) initn: 2842 init1: 2321 opt: 2826 Z-score: 1831.0 bits: 348.7 E(85289): 3e-95 Smith-Waterman score: 2826; 97.3% identity (98.6% similar) in 437 aa overlap (1-436:1-437) 10 20 30 40 50 60 pF1KB6 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQ-KRPNPELRRNMTIKTEL :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_011 ANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQQKRPNPELRRNMTIKTEL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 PLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 APKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKV ::::. . .. .:.: XP_011 APKVFGEQVVFGYMSAAS 430 763 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:02:23 2016 done: Sat Nov 5 14:02:25 2016 Total Scan time: 13.710 Total Display time: 0.220 Function used was FASTA [36.3.4 Apr, 2011]