FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6292, 789 aa 1>>>pF1KB6292 789 - 789 aa - 789 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1105+/-0.000466; mu= -0.5995+/- 0.029 mean_var=358.9389+/-74.566, 0's: 0 Z-trim(120.3): 1957 B-trim: 146 in 1/57 Lambda= 0.067696 statistics sampled from 33219 (35406) to 33219 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.415), width: 16 Scan time: 12.550 The best scores are: opt bits E(85289) XP_011534365 (OMIM: 603423) PREDICTED: PR domain z ( 789) 5409 543.1 1.7e-153 XP_016866676 (OMIM: 603423) PREDICTED: PR domain z ( 789) 5409 543.1 1.7e-153 NP_001189 (OMIM: 603423) PR domain zinc finger pro ( 825) 5409 543.1 1.8e-153 XP_011534364 (OMIM: 603423) PREDICTED: PR domain z ( 839) 5409 543.1 1.8e-153 NP_878911 (OMIM: 603423) PR domain zinc finger pro ( 691) 4721 475.8 2.7e-133 XP_011534366 (OMIM: 603423) PREDICTED: PR domain z ( 667) 4565 460.6 1e-128 XP_006715613 (OMIM: 603423) PREDICTED: PR domain z ( 796) 3808 386.7 2e-106 NP_001108231 (OMIM: 616775) tissue-resident T-cell ( 504) 814 94.1 1.6e-18 NP_775845 (OMIM: 616775) tissue-resident T-cell tr ( 504) 814 94.1 1.6e-18 XP_016856446 (OMIM: 616775) PREDICTED: zinc finger ( 513) 814 94.1 1.6e-18 XP_005245887 (OMIM: 616775) PREDICTED: zinc finger ( 524) 616 74.8 1.1e-12 XP_011539500 (OMIM: 616775) PREDICTED: zinc finger ( 524) 616 74.8 1.1e-12 NP_001294854 (OMIM: 616775) tissue-resident T-cell ( 524) 616 74.8 1.1e-12 XP_005245889 (OMIM: 616775) PREDICTED: zinc finger ( 524) 616 74.8 1.1e-12 XP_005245885 (OMIM: 616775) PREDICTED: zinc finger ( 532) 616 74.8 1.1e-12 XP_016856445 (OMIM: 616775) PREDICTED: zinc finger ( 532) 616 74.8 1.1e-12 XP_006710618 (OMIM: 616775) PREDICTED: zinc finger ( 533) 616 74.8 1.1e-12 XP_016856443 (OMIM: 616775) PREDICTED: zinc finger ( 533) 616 74.8 1.1e-12 XP_016856444 (OMIM: 616775) PREDICTED: zinc finger ( 533) 616 74.8 1.1e-12 XP_011525220 (OMIM: 165260) PREDICTED: zinc finger ( 327) 544 67.5 1e-10 XP_016882236 (OMIM: 165260) PREDICTED: zinc finger ( 327) 544 67.5 1e-10 XP_006723255 (OMIM: 165260) PREDICTED: zinc finger ( 491) 544 67.7 1.3e-10 NP_001308045 (OMIM: 165260) zinc finger and SCAN d ( 491) 544 67.7 1.3e-10 NP_862829 (OMIM: 165260) zinc finger and SCAN doma ( 491) 544 67.7 1.3e-10 XP_011525219 (OMIM: 165260) PREDICTED: zinc finger ( 491) 544 67.7 1.3e-10 NP_001311277 (OMIM: 601069) zinc finger protein 23 ( 458) 534 66.7 2.5e-10 NP_001311280 (OMIM: 601069) zinc finger protein 23 ( 458) 534 66.7 2.5e-10 NP_001092753 (OMIM: 601069) zinc finger protein 23 ( 458) 534 66.7 2.5e-10 NP_001092754 (OMIM: 601069) zinc finger protein 23 ( 458) 534 66.7 2.5e-10 XP_005271889 (OMIM: 601069) PREDICTED: zinc finger ( 458) 534 66.7 2.5e-10 NP_001092752 (OMIM: 601069) zinc finger protein 23 ( 458) 534 66.7 2.5e-10 XP_011538540 (OMIM: 601069) PREDICTED: zinc finger ( 458) 534 66.7 2.5e-10 NP_001311276 (OMIM: 601069) zinc finger protein 23 ( 458) 534 66.7 2.5e-10 NP_001311279 (OMIM: 601069) zinc finger protein 23 ( 458) 534 66.7 2.5e-10 XP_006718066 (OMIM: 601069) PREDICTED: zinc finger ( 458) 534 66.7 2.5e-10 NP_005665 (OMIM: 601069) zinc finger protein 239 i ( 458) 534 66.7 2.5e-10 NP_001311278 (OMIM: 601069) zinc finger protein 23 ( 458) 534 66.7 2.5e-10 XP_011538536 (OMIM: 601069) PREDICTED: zinc finger ( 500) 534 66.8 2.7e-10 XP_006718064 (OMIM: 601069) PREDICTED: zinc finger ( 500) 534 66.8 2.7e-10 XP_011538539 (OMIM: 601069) PREDICTED: zinc finger ( 500) 534 66.8 2.7e-10 XP_011538537 (OMIM: 601069) PREDICTED: zinc finger ( 500) 534 66.8 2.7e-10 XP_011538538 (OMIM: 601069) PREDICTED: zinc finger ( 500) 534 66.8 2.7e-10 XP_016872229 (OMIM: 601069) PREDICTED: zinc finger ( 500) 534 66.8 2.7e-10 NP_001311281 (OMIM: 601069) zinc finger protein 23 ( 500) 534 66.8 2.7e-10 XP_005259469 (OMIM: 604749) PREDICTED: zinc finger ( 734) 537 67.2 2.8e-10 NP_004225 (OMIM: 604749) zinc finger protein 235 [ ( 738) 537 67.2 2.9e-10 NP_001311282 (OMIM: 601069) zinc finger protein 23 ( 571) 534 66.8 2.9e-10 XP_016882933 (OMIM: 616841) PREDICTED: zinc finger ( 469) 532 66.5 2.9e-10 XP_011538534 (OMIM: 601069) PREDICTED: zinc finger ( 602) 534 66.9 3e-10 NP_001008801 (OMIM: 616841) zinc finger protein 46 ( 522) 532 66.6 3.2e-10 >>XP_011534365 (OMIM: 603423) PREDICTED: PR domain zinc (789 aa) initn: 5409 init1: 5409 opt: 5409 Z-score: 2876.6 bits: 543.1 E(85289): 1.7e-153 Smith-Waterman score: 5409; 99.9% identity (100.0% similar) in 789 aa overlap (1-789:1-789) 10 20 30 40 50 60 pF1KB6 MKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRNLLFKYATNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRNLLFKYATNSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCREFAERLHYPYPGEL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_011 NWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 EKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 PHPMLNPTSLPSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PHPMLNPTSLPSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 PTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 CNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 HKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 IHLCSLKVHLKGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHLCSLKVHLKGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 KEILAVVRKEKEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEILAVVRKEKEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVK 730 740 750 760 770 780 pF1KB6 QETVEPMDP ::::::::: XP_011 QETVEPMDP >>XP_016866676 (OMIM: 603423) PREDICTED: PR domain zinc (789 aa) initn: 5409 init1: 5409 opt: 5409 Z-score: 2876.6 bits: 543.1 E(85289): 1.7e-153 Smith-Waterman score: 5409; 99.9% identity (100.0% similar) in 789 aa overlap (1-789:1-789) 10 20 30 40 50 60 pF1KB6 MKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRNLLFKYATNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRNLLFKYATNSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCREFAERLHYPYPGEL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 NWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 EKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 PHPMLNPTSLPSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHPMLNPTSLPSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 PTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 CNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 HKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 IHLCSLKVHLKGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHLCSLKVHLKGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB6 KEILAVVRKEKEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEILAVVRKEKEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVK 730 740 750 760 770 780 pF1KB6 QETVEPMDP ::::::::: XP_016 QETVEPMDP >>NP_001189 (OMIM: 603423) PR domain zinc finger protein (825 aa) initn: 5409 init1: 5409 opt: 5409 Z-score: 2876.3 bits: 543.1 E(85289): 1.8e-153 Smith-Waterman score: 5409; 99.9% identity (100.0% similar) in 789 aa overlap (1-789:37-825) 10 20 30 pF1KB6 MKMDMEDADMTLWTEAEFEEKCTYIVNDHP :::::::::::::::::::::::::::::: NP_001 EKRVGTTLAAPKCNSSTVRFQGLAEGTKGTMKMDMEDADMTLWTEAEFEEKCTYIVNDHP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 WDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 PKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYT 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 IKPIPANQELLVWYCREFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKR ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 IKPIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 EYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLP 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 EDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPG 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 SQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLS 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB6 AVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPRE 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB6 VLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEA 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB6 MNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQ 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB6 TCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPA 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB6 KFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRI 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB6 NEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLS 730 740 750 760 770 780 760 770 780 pF1KB6 SGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP ::::::::::::::::::::::::::::::::::::::: NP_001 SGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP 790 800 810 820 >>XP_011534364 (OMIM: 603423) PREDICTED: PR domain zinc (839 aa) initn: 5409 init1: 5409 opt: 5409 Z-score: 2876.2 bits: 543.1 E(85289): 1.8e-153 Smith-Waterman score: 5409; 99.9% identity (100.0% similar) in 789 aa overlap (1-789:51-839) 10 20 30 pF1KB6 MKMDMEDADMTLWTEAEFEEKCTYIVNDHP :::::::::::::::::::::::::::::: XP_011 GKARDCSEAAPKCNSSTVRFQGLAEGTKGTMKMDMEDADMTLWTEAEFEEKCTYIVNDHP 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB6 WDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTV 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB6 PKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYT 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB6 IKPIPANQELLVWYCREFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKR ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_011 IKPIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKR 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB6 EYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLP 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB6 EDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPG 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB6 SQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLS 390 400 410 420 430 440 400 410 420 430 440 450 pF1KB6 AVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPRE 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB6 VLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEA 510 520 530 540 550 560 520 530 540 550 560 570 pF1KB6 MNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQ 570 580 590 600 610 620 580 590 600 610 620 630 pF1KB6 TCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPA 630 640 650 660 670 680 640 650 660 670 680 690 pF1KB6 KFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRI 690 700 710 720 730 740 700 710 720 730 740 750 pF1KB6 NEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLS 750 760 770 780 790 800 760 770 780 pF1KB6 SGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP ::::::::::::::::::::::::::::::::::::::: XP_011 SGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP 810 820 830 >>NP_878911 (OMIM: 603423) PR domain zinc finger protein (691 aa) initn: 4721 init1: 4721 opt: 4721 Z-score: 2514.1 bits: 475.8 E(85289): 2.7e-133 Smith-Waterman score: 4721; 99.7% identity (100.0% similar) in 689 aa overlap (101-789:3-691) 80 90 100 110 120 130 pF1KB6 IPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAH .::::::::::::::::::::::::::::: NP_878 MEKIYSRGELHHFIDGFNEEKSNWMRYVNPAH 10 20 30 140 150 160 170 180 190 pF1KB6 SPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCREFAERLHYPYPGELTMMNLTQTQS ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_878 SPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 SLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 SLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 GSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 GSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQS 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 LKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 LKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSY 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB6 NAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 NAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSL 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB6 PSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 PSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAE 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB6 HVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 HVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQ 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB6 LSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 LSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNL 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB6 KTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 KTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHL 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB6 KGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 KGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKE 580 590 600 610 620 630 740 750 760 770 780 pF1KB6 KEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_878 KEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP 640 650 660 670 680 690 >>XP_011534366 (OMIM: 603423) PREDICTED: PR domain zinc (667 aa) initn: 4565 init1: 4565 opt: 4565 Z-score: 2432.0 bits: 460.6 E(85289): 1e-128 Smith-Waterman score: 4565; 99.9% identity (100.0% similar) in 667 aa overlap (123-789:1-667) 100 110 120 130 140 150 pF1KB6 NANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYTIK :::::::::::::::::::::::::::::: XP_011 MRYVNPAHSPREQNLAACQNGMNIYFYTIK 10 20 30 160 170 180 190 200 210 pF1KB6 PIPANQELLVWYCREFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKREY ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKREY 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB6 SVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLPED 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB6 FLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQ 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB6 EHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAV 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB6 SSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPREVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPREVL 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB6 VPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEAMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEAMN 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB6 LIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTC 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB6 NKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKF 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB6 TQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRINE 520 530 540 550 560 570 700 710 720 730 740 750 pF1KB6 EIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLSSG 580 590 600 610 620 630 760 770 780 pF1KB6 CSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP ::::::::::::::::::::::::::::::::::::: XP_011 CSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP 640 650 660 >>XP_006715613 (OMIM: 603423) PREDICTED: PR domain zinc (796 aa) initn: 4214 init1: 3803 opt: 3808 Z-score: 2031.5 bits: 386.7 E(85289): 2e-106 Smith-Waterman score: 4995; 94.4% identity (94.6% similar) in 789 aa overlap (1-789:51-796) 10 20 30 pF1KB6 MKMDMEDADMTLWTEAEFEEKCTYIVNDHP :::::::::::::::::::::::::::::: XP_006 GKARDCSEAAPKCNSSTVRFQGLAEGTKGTMKMDMEDADMTLWTEAEFEEKCTYIVNDHP 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB6 WDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTV 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB6 PKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYT 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB6 IKPIPANQELLVWYCREFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKR ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_006 IKPIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKR 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB6 EYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLP 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB6 EDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPG 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB6 SQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLS 390 400 410 420 430 440 400 410 420 430 440 450 pF1KB6 AVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPRE 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB6 VLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEA 510 520 530 540 550 560 520 530 540 550 560 570 pF1KB6 MNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQ :::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKV-------------- 570 580 590 600 580 590 600 610 620 630 pF1KB6 TCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPA ::::::::::::::::::::::::::::::: XP_006 -----------------------------CHKRFSSTSNLKTHLRLHSGEKPYQCKVCPA 610 620 630 640 650 660 670 680 690 pF1KB6 KFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRI 640 650 660 670 680 690 700 710 720 730 740 750 pF1KB6 NEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLS 700 710 720 730 740 750 760 770 780 pF1KB6 SGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP ::::::::::::::::::::::::::::::::::::::: XP_006 SGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP 760 770 780 790 >>NP_001108231 (OMIM: 616775) tissue-resident T-cell tra (504 aa) initn: 763 init1: 735 opt: 814 Z-score: 453.6 bits: 94.1 E(85289): 1.6e-18 Smith-Waterman score: 827; 39.8% identity (61.2% similar) in 405 aa overlap (299-701:111-473) 270 280 290 300 310 320 pF1KB6 LPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVG :. .: :. :... . :... .: NP_001 DLNLCTPQPAPLGTDLQGLQEDALSMKHEPPGLQASSTDDKKFTVKYPQNKDKLGKQPER 90 100 110 120 130 140 330 340 350 360 370 380 pF1KB6 PGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNG : ... :.: . : . . .:: : . : . . : ::: . : NP_001 AGEGAPCPAFSSHNSS-SPPPLQNRKSPSPLAFCPCPPVNSISKELP-FLLHAF---YPG 150 160 170 180 190 390 400 410 420 430 440 pF1KB6 LSAVSSMNGINNFGLFPR-LCPVYSNLLGGGSLPHPMLNPT-SLPSSLPSDGARRLLQPE . . ..: .: :: .:: ::. :: ..:: : . .: .: NP_001 YPLLLPPPHLFTYGALPSDQCP---HLL---MLPQDPSYPTMAMPSLLMM--VNELGHPS 200 210 220 230 240 450 460 470 480 490 500 pF1KB6 HPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPS :.:.: : .::. .: : . . .: ::.: : .: ..::.:. NP_001 ARWETLLPYP-GAFQASGQALPSQAR-------NPGAGAAPTD----SPGLERGGMASPA 250 260 270 280 290 510 520 530 540 550 560 pF1KB6 SDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERP . .. ..:: .:::::::.:::: ::::.:.:.::::::::::::::::::: NP_001 KRVPLS------SQTGTAALPYPLKKKNGKILYECNICGKSFGQLSNLKVHLRVHSGERP 300 310 320 330 340 570 580 590 600 610 620 pF1KB6 FKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCK :.: :.:.::::::::::.::::::.::.:.::::::::.:::::::::::: .:.::. NP_001 FQCALCQKSFTQLAHLQKHHLVHTGERPHKCSVCHKRFSSSSNLKTHLRLHSGARPFQCS 350 360 370 380 390 400 630 640 650 660 670 680 pF1KB6 VCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLED :: ..::: .:::::.:::. :. :. : . . : :: : : : :. NP_001 VCRSRFTQHIHLKLHHRLHA---PQPCGLVHTQ-LPLASLA------CLAQWHQG-ALDL 410 420 430 440 450 690 700 710 720 730 740 pF1KB6 LTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGN .. .:. .::.. NP_001 MAVASEKHMGYDIDEVKVSSTSQGKARAVSLSSAGTPLVMGQDQNN 460 470 480 490 500 >>NP_775845 (OMIM: 616775) tissue-resident T-cell transc (504 aa) initn: 763 init1: 735 opt: 814 Z-score: 453.6 bits: 94.1 E(85289): 1.6e-18 Smith-Waterman score: 827; 39.8% identity (61.2% similar) in 405 aa overlap (299-701:111-473) 270 280 290 300 310 320 pF1KB6 LPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVG :. .: :. :... . :... .: NP_775 DLNLCTPQPAPLGTDLQGLQEDALSMKHEPPGLQASSTDDKKFTVKYPQNKDKLGKQPER 90 100 110 120 130 140 330 340 350 360 370 380 pF1KB6 PGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNG : ... :.: . : . . .:: : . : . . : ::: . : NP_775 AGEGAPCPAFSSHNSS-SPPPLQNRKSPSPLAFCPCPPVNSISKELP-FLLHAF---YPG 150 160 170 180 190 390 400 410 420 430 440 pF1KB6 LSAVSSMNGINNFGLFPR-LCPVYSNLLGGGSLPHPMLNPT-SLPSSLPSDGARRLLQPE . . ..: .: :: .:: ::. :: ..:: : . .: .: NP_775 YPLLLPPPHLFTYGALPSDQCP---HLL---MLPQDPSYPTMAMPSLLMM--VNELGHPS 200 210 220 230 240 450 460 470 480 490 500 pF1KB6 HPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPS :.:.: : .::. .: : . . .: ::.: : .: ..::.:. NP_775 ARWETLLPYP-GAFQASGQALPSQAR-------NPGAGAAPTD----SPGLERGGMASPA 250 260 270 280 290 510 520 530 540 550 560 pF1KB6 SDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERP . .. ..:: .:::::::.:::: ::::.:.:.::::::::::::::::::: NP_775 KRVPLS------SQTGTAALPYPLKKKNGKILYECNICGKSFGQLSNLKVHLRVHSGERP 300 310 320 330 340 570 580 590 600 610 620 pF1KB6 FKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCK :.: :.:.::::::::::.::::::.::.:.::::::::.:::::::::::: .:.::. NP_775 FQCALCQKSFTQLAHLQKHHLVHTGERPHKCSVCHKRFSSSSNLKTHLRLHSGARPFQCS 350 360 370 380 390 400 630 640 650 660 670 680 pF1KB6 VCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLED :: ..::: .:::::.:::. :. :. : . . : :: : : : :. NP_775 VCRSRFTQHIHLKLHHRLHA---PQPCGLVHTQ-LPLASLA------CLAQWHQG-ALDL 410 420 430 440 450 690 700 710 720 730 740 pF1KB6 LTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGN .. .:. .::.. NP_775 MAVASEKHMGYDIDEVKVSSTSQGKARAVSLSSAGTPLVMGQDQNN 460 470 480 490 500 >>XP_016856446 (OMIM: 616775) PREDICTED: zinc finger pro (513 aa) initn: 763 init1: 735 opt: 814 Z-score: 453.5 bits: 94.1 E(85289): 1.6e-18 Smith-Waterman score: 827; 39.8% identity (61.2% similar) in 405 aa overlap (299-701:120-482) 270 280 290 300 310 320 pF1KB6 LPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVG :. .: :. :... . :... .: XP_016 DLNLCTPQPAPLGTDLQGLQEDALSMKHEPPGLQASSTDDKKFTVKYPQNKDKLGKQPER 90 100 110 120 130 140 330 340 350 360 370 380 pF1KB6 PGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNG : ... :.: . : . . .:: : . : . . : ::: . : XP_016 AGEGAPCPAFSSHNSS-SPPPLQNRKSPSPLAFCPCPPVNSISKELP-FLLHAF---YPG 150 160 170 180 190 200 390 400 410 420 430 440 pF1KB6 LSAVSSMNGINNFGLFPR-LCPVYSNLLGGGSLPHPMLNPT-SLPSSLPSDGARRLLQPE . . ..: .: :: .:: ::. :: ..:: : . .: .: XP_016 YPLLLPPPHLFTYGALPSDQCP---HLL---MLPQDPSYPTMAMPSLLMM--VNELGHPS 210 220 230 240 250 450 460 470 480 490 500 pF1KB6 HPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPS :.:.: : .::. .: : . . .: ::.: : .: ..::.:. XP_016 ARWETLLPYP-GAFQASGQALPSQAR-------NPGAGAAPTD----SPGLERGGMASPA 260 270 280 290 300 510 520 530 540 550 560 pF1KB6 SDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERP . .. ..:: .:::::::.:::: ::::.:.:.::::::::::::::::::: XP_016 KRVPLS------SQTGTAALPYPLKKKNGKILYECNICGKSFGQLSNLKVHLRVHSGERP 310 320 330 340 350 570 580 590 600 610 620 pF1KB6 FKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCK :.: :.:.::::::::::.::::::.::.:.::::::::.:::::::::::: .:.::. XP_016 FQCALCQKSFTQLAHLQKHHLVHTGERPHKCSVCHKRFSSSSNLKTHLRLHSGARPFQCS 360 370 380 390 400 410 630 640 650 660 670 680 pF1KB6 VCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLED :: ..::: .:::::.:::. :. :. : . . : :: : : : :. XP_016 VCRSRFTQHIHLKLHHRLHA---PQPCGLVHTQ-LPLASLA------CLAQWHQG-ALDL 420 430 440 450 460 690 700 710 720 730 740 pF1KB6 LTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGN .. .:. .::.. XP_016 MAVASEKHMGYDIDEVKVSSTSQGKARAVSLSSAGTPLVMGQDQNN 470 480 490 500 510 789 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:03:02 2016 done: Sat Nov 5 14:03:04 2016 Total Scan time: 12.550 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]