FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6302, 277 aa 1>>>pF1KB6302 277 - 277 aa - 277 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7012+/-0.000343; mu= 17.5898+/- 0.021 mean_var=54.5077+/-11.052, 0's: 0 Z-trim(112.8): 10 B-trim: 0 in 0/52 Lambda= 0.173718 statistics sampled from 21854 (21858) to 21854 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.256), width: 16 Scan time: 6.960 The best scores are: opt bits E(85289) NP_002346 (OMIM: 154540) cation-dependent mannose- ( 277) 1880 479.2 3.8e-135 XP_005253433 (OMIM: 154540) PREDICTED: cation-depe ( 277) 1880 479.2 3.8e-135 NP_001193953 (OMIM: 154540) cation-dependent manno ( 191) 1027 265.3 6.3e-71 >>NP_002346 (OMIM: 154540) cation-dependent mannose-6-ph (277 aa) initn: 1880 init1: 1880 opt: 1880 Z-score: 2547.4 bits: 479.2 E(85289): 3.8e-135 Smith-Waterman score: 1880; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KB6 MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC 190 200 210 220 230 240 250 260 270 pF1KB6 DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM ::::::::::::::::::::::::::::::::::::: NP_002 DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM 250 260 270 >>XP_005253433 (OMIM: 154540) PREDICTED: cation-dependen (277 aa) initn: 1880 init1: 1880 opt: 1880 Z-score: 2547.4 bits: 479.2 E(85289): 3.8e-135 Smith-Waterman score: 1880; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KB6 MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC 190 200 210 220 230 240 250 260 270 pF1KB6 DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM ::::::::::::::::::::::::::::::::::::: XP_005 DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM 250 260 270 >>NP_001193953 (OMIM: 154540) cation-dependent mannose-6 (191 aa) initn: 1027 init1: 1027 opt: 1027 Z-score: 1394.4 bits: 265.3 E(85289): 6.3e-71 Smith-Waterman score: 1125; 69.0% identity (69.0% similar) in 277 aa overlap (1-277:1-191) 10 20 30 40 50 60 pF1KB6 MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS :::::::::::::::::::::::::::::::: NP_001 IYKGGDEYDNHCGKEQRRAVVMISCNRHTLAD---------------------------- 130 140 150 190 200 210 220 230 240 pF1KB6 PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC :: NP_001 ----------------------------------------------------------GC 250 260 270 pF1KB6 DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM ::::::::::::::::::::::::::::::::::::: NP_001 DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM 160 170 180 190 277 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:02:31 2016 done: Sat Nov 5 11:02:32 2016 Total Scan time: 6.960 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]