FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6307, 258 aa 1>>>pF1KB6307 258 - 258 aa - 258 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3865+/-0.000724; mu= 12.9071+/- 0.044 mean_var=156.5482+/-30.488, 0's: 0 Z-trim(115.6): 168 B-trim: 0 in 0/51 Lambda= 0.102506 statistics sampled from 16235 (16405) to 16235 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.491), width: 16 Scan time: 1.230 The best scores are: opt bits E(33420) CCDS1575.1 RHOU gene_id:58480|Hs109|chr1 ( 258) 1796 276.3 1.5e-74 CCDS10068.1 RHOV gene_id:171177|Hs109|chr15 ( 236) 889 142.2 3.3e-34 CCDS221.1 CDC42 gene_id:998|Hs109|chr1 ( 191) 769 124.3 6.3e-29 CCDS222.1 CDC42 gene_id:998|Hs109|chr1 ( 191) 769 124.3 6.3e-29 CCDS5348.1 RAC1 gene_id:5879|Hs109|chr7 ( 192) 715 116.3 1.6e-26 CCDS13945.1 RAC2 gene_id:5880|Hs109|chr22 ( 192) 710 115.6 2.7e-26 CCDS11798.1 RAC3 gene_id:5881|Hs109|chr17 ( 192) 703 114.5 5.5e-26 CCDS33191.1 RHOQ gene_id:23433|Hs109|chr2 ( 205) 683 111.6 4.4e-25 CCDS9757.1 RHOJ gene_id:57381|Hs109|chr14 ( 214) 661 108.4 4.3e-24 CCDS7748.1 RHOG gene_id:391|Hs109|chr11 ( 191) 635 104.5 5.8e-23 CCDS854.1 RHOC gene_id:389|Hs109|chr1 ( 193) 605 100.1 1.3e-21 CCDS2795.1 RHOA gene_id:387|Hs109|chr3 ( 193) 593 98.3 4.3e-21 CCDS1699.1 RHOB gene_id:388|Hs109|chr2 ( 196) 593 98.3 4.4e-21 CCDS8155.1 RHOD gene_id:29984|Hs109|chr11 ( 210) 527 88.6 4e-18 CCDS9222.1 RHOF gene_id:54509|Hs109|chr12 ( 211) 522 87.8 6.6e-18 CCDS82775.1 RHOA gene_id:387|Hs109|chr3 ( 187) 497 84.1 8e-17 CCDS2190.1 RND3 gene_id:390|Hs109|chr2 ( 244) 495 83.9 1.2e-16 CCDS11452.1 RND2 gene_id:8153|Hs109|chr17 ( 227) 481 81.8 4.7e-16 CCDS3458.1 RHOH gene_id:399|Hs109|chr4 ( 191) 471 80.2 1.2e-15 CCDS8771.1 RND1 gene_id:27289|Hs109|chr12 ( 232) 438 75.4 3.9e-14 CCDS5349.1 RAC1 gene_id:5879|Hs109|chr7 ( 211) 377 66.4 1.9e-11 >>CCDS1575.1 RHOU gene_id:58480|Hs109|chr1 (258 aa) initn: 1796 init1: 1796 opt: 1796 Z-score: 1452.3 bits: 276.3 E(33420): 1.5e-74 Smith-Waterman score: 1796; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258) 10 20 30 40 50 60 pF1KB6 MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 GKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 TDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 KPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTP 190 200 210 220 230 240 250 pF1KB6 DKMKNLSKSWWKKYCCFV :::::::::::::::::: CCDS15 DKMKNLSKSWWKKYCCFV 250 >>CCDS10068.1 RHOV gene_id:171177|Hs109|chr15 (236 aa) initn: 935 init1: 655 opt: 889 Z-score: 727.9 bits: 142.2 E(33420): 3.3e-34 Smith-Waterman score: 905; 54.4% identity (76.1% similar) in 259 aa overlap (1-258:1-236) 10 20 30 40 50 60 pF1KB6 MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAV :::.. . : : .:: ::::. . : : :.:::::::::: CCDS10 MPPRELSEAEPPPLRAPTPPPRRRSA------PPE------------LGIKCVLVGDGAV 10 20 30 40 70 80 90 100 110 120 pF1KB6 GKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTN ::.::.:::: ::::..: :::.:.::. : ::: :::..: :::::..::.:: ::: . CCDS10 GKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPD 50 60 70 80 90 100 130 140 150 160 170 pF1KB6 TDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKC-K ::.:: :::::.::::::..:::.:::: : :.::..:::::.:::.::.:::.::. . CCDS10 TDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 EKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRT : :::. :. ::.:.: :.:::::::::::::::.::...:... .. ..:. CCDS10 EGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKG-- 170 180 190 200 210 220 240 250 pF1KB6 PDKMKNLSKSWWKKYCCFV ...::. :::. ::: CCDS10 ---VRTLSRCRWKKFFCFV 230 >>CCDS221.1 CDC42 gene_id:998|Hs109|chr1 (191 aa) initn: 792 init1: 753 opt: 769 Z-score: 633.0 bits: 124.3 E(33420): 6.3e-29 Smith-Waterman score: 769; 60.1% identity (85.1% similar) in 188 aa overlap (50-236:4-186) 20 30 40 50 60 70 pF1KB6 PPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYI .:::.::::::::: :..::::: .:.::. CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYV 10 20 30 80 90 100 110 120 130 pF1KB6 PTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNV ::.:::....: . :.: : : :::::...:.:::: : .::.::.::::::::::.:: CCDS22 PTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENV 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 SEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPV-PEEAAKLCAEEIKAA .::::::: ::::.:..::::: :::.: ... .: : :.::. :: : :: :...::. CCDS22 KEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKL-ARDLKAV 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 SYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCFV .:.::::::::.::.::: ::.:... .::::. CCDS22 KYVECSALTQKGLKNVFDEAILAALE----PPEPKKSRRCVLL 160 170 180 190 >>CCDS222.1 CDC42 gene_id:998|Hs109|chr1 (191 aa) initn: 786 init1: 763 opt: 769 Z-score: 633.0 bits: 124.3 E(33420): 6.3e-29 Smith-Waterman score: 769; 60.2% identity (86.0% similar) in 186 aa overlap (50-234:4-186) 20 30 40 50 60 70 pF1KB6 PPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYI .:::.::::::::: :..::::: .:.::. CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYV 10 20 30 80 90 100 110 120 130 pF1KB6 PTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNV ::.:::....: . :.: : : :::::...:.:::: : .::.::.::::::::::.:: CCDS22 PTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENV 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 SEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPV-PEEAAKLCAEEIKAA .::::::: ::::.:..::::: :::.: ... .: : :.::. :: : :: :...::. CCDS22 KEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKL-ARDLKAV 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 SYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCFV .:.:::::::..::.::: ::.:... .:: ::. CCDS22 KYVECSALTQRGLKNVFDEAILAALEPPETQ--PKRKCCIF 160 170 180 190 >>CCDS5348.1 RAC1 gene_id:5879|Hs109|chr7 (192 aa) initn: 707 init1: 707 opt: 715 Z-score: 589.9 bits: 116.3 E(33420): 1.6e-26 Smith-Waterman score: 715; 56.1% identity (79.7% similar) in 187 aa overlap (48-234:2-188) 20 30 40 50 60 70 pF1KB6 PVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTE ...:::.::::::::: :..:::::..: : CCDS53 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGE 10 20 30 80 90 100 110 120 130 pF1KB6 YIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQ ::::.:::.:: : :::.:: : : :::::...:.:::: : .::.::.:::.:::.::. CCDS53 YIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 NVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKA :: :: ::.: :::..:::::::. :::.: .. .: . : :. . :.:: : CCDS53 NVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGA 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 ASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCF ..:.:::::::..:: ::: :: : . .... .: CCDS53 VKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 160 170 180 190 pF1KB6 V >>CCDS13945.1 RAC2 gene_id:5880|Hs109|chr22 (192 aa) initn: 723 init1: 705 opt: 710 Z-score: 585.9 bits: 115.6 E(33420): 2.7e-26 Smith-Waterman score: 710; 55.9% identity (80.1% similar) in 186 aa overlap (48-233:2-187) 20 30 40 50 60 70 pF1KB6 PVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTE ...:::.::::::::: :..:::::..: : CCDS13 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGE 10 20 30 80 90 100 110 120 130 pF1KB6 YIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQ ::::.:::.:: : ::..:: : : :::::...:.:::: : .::.::.:::.:::.:.. CCDS13 YIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 NVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKA :: :: ::.: :::..:::::::. :::.: .. .: . : :. . :.:: . CCDS13 NVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 ASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCF ..:.:::::::..:: ::: :: : . . :.:: . CCDS13 VKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 160 170 180 190 pF1KB6 V >>CCDS11798.1 RAC3 gene_id:5881|Hs109|chr17 (192 aa) initn: 703 init1: 703 opt: 703 Z-score: 580.3 bits: 114.5 E(33420): 5.5e-26 Smith-Waterman score: 703; 55.6% identity (78.6% similar) in 187 aa overlap (48-234:2-188) 20 30 40 50 60 70 pF1KB6 PVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTE ...:::.::::::::: :..:::::..: : CCDS11 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGE 10 20 30 80 90 100 110 120 130 pF1KB6 YIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQ ::::.:::.:: : :::.:: : : :::::...:.:::: : .::.::.:::.:::.::. CCDS11 YIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 NVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKA :: :: ::.: :::..::.::::. :::.: .. .: : :. . :.:: . CCDS11 NVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 ASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCF ..:.:::::::..:: ::: :: : . ... :: CCDS11 VKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF 160 170 180 190 pF1KB6 V >>CCDS33191.1 RHOQ gene_id:23433|Hs109|chr2 (205 aa) initn: 713 init1: 680 opt: 683 Z-score: 563.9 bits: 111.6 E(33420): 4.4e-25 Smith-Waterman score: 683; 55.6% identity (81.7% similar) in 180 aa overlap (45-221:2-181) 20 30 40 50 60 70 pF1KB6 EAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRG---VKCVLVGDGAVGKTSLVVSYTT :.: : .:::.::::::::: :..::.. CCDS33 MAHGPGALMLKCVVVGDGAVGKTCLLMSYAN 10 20 30 80 90 100 110 120 130 pF1KB6 NGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVV ...: ::.::.::.... :.: :. : : :::::...:.:::: : ::.::.::::: CCDS33 DAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVV 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 SPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLC .:.:::::.:.::::.. . :..:..:.::: :::.: :.: .:. ::::. : .. CCDS33 NPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKL 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 AEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWW :.:: : :.::::::::.:: ::: ::.: CCDS33 AKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT 160 170 180 190 200 >>CCDS9757.1 RHOJ gene_id:57381|Hs109|chr14 (214 aa) initn: 657 init1: 636 opt: 661 Z-score: 546.1 bits: 108.4 E(33420): 4.3e-24 Smith-Waterman score: 661; 50.2% identity (76.1% similar) in 205 aa overlap (34-238:6-203) 10 20 30 40 50 60 pF1KB6 QQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKT : .. : :. : . .:::.::::::::: CCDS97 MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKT 10 20 30 70 80 90 100 110 120 pF1KB6 SLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDI :..::.....: ::.::.::.....:.: :. : : :::::.....:::: : :::. CCDS97 CLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 FLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPV ::.:::::.:.:..::.:.::::.. :..: .:.::: :::.: :.: .: ::::. CCDS97 FLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 PEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKM : . :. : : :.::::::::.:: ::: ::. : .:::.:.: CCDS97 TYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAIL-------TIFHPKKKKKRCSEGH 160 170 180 190 200 250 pF1KB6 KNLSKSWWKKYCCFV CCDS97 SCCSII 210 >>CCDS7748.1 RHOG gene_id:391|Hs109|chr11 (191 aa) initn: 630 init1: 630 opt: 635 Z-score: 525.9 bits: 104.5 E(33420): 5.8e-23 Smith-Waterman score: 635; 52.3% identity (79.3% similar) in 174 aa overlap (48-221:2-175) 20 30 40 50 60 70 pF1KB6 PVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTE ...:::.::::::::: :.. ::::..: : CCDS77 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKE 10 20 30 80 90 100 110 120 130 pF1KB6 YIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQ ::::.:::.:: .:::: : :.: :::::.:.:.:: : : .:..:..:::..:: :.. CCDS77 YIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 NVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKA :: .:: ::. ::: .::.::::..::: . .: .: . . :. . .. :..:.: CCDS77 NVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHA 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 ASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCF . :.::::: : ..:::: :. : CCDS77 VRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL 160 170 180 190 258 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:30:04 2019 done: Thu Oct 24 21:30:05 2019 Total Scan time: 1.230 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]