FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6309, 258 aa 1>>>pF1KB6309 258 - 258 aa - 258 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7935+/-0.000579; mu= 12.7618+/- 0.035 mean_var=75.0733+/-15.190, 0's: 0 Z-trim(113.6): 8 B-trim: 0 in 0/49 Lambda= 0.148024 statistics sampled from 14192 (14197) to 14192 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.436), width: 16 Scan time: 2.770 The best scores are: opt bits E(32554) CCDS12361.1 PGLS gene_id:25796|Hs108|chr19 ( 258) 1700 371.5 3.2e-103 CCDS101.1 H6PD gene_id:9563|Hs108|chr1 ( 791) 354 84.3 2.8e-16 CCDS72697.1 H6PD gene_id:9563|Hs108|chr1 ( 802) 354 84.3 2.9e-16 >>CCDS12361.1 PGLS gene_id:25796|Hs108|chr19 (258 aa) initn: 1700 init1: 1700 opt: 1700 Z-score: 1966.6 bits: 371.5 E(32554): 3.2e-103 Smith-Waterman score: 1700; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258) 10 20 30 40 50 60 pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 AVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFL 190 200 210 220 230 240 250 pF1KB6 DEAAARLLTVPFEKHSTL :::::::::::::::::: CCDS12 DEAAARLLTVPFEKHSTL 250 >>CCDS101.1 H6PD gene_id:9563|Hs108|chr1 (791 aa) initn: 291 init1: 174 opt: 354 Z-score: 405.7 bits: 84.3 E(32554): 2.8e-16 Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:555-788) 10 20 30 pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA :.:.. :.:: . ::. . .:. : CCDS10 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR 530 540 550 560 570 580 40 50 60 70 80 90 pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY : ..: :.::::: : ..: :.: : : :. : . ::: ::.. ::.. CCDS10 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL 590 600 610 620 630 100 110 120 130 140 pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV ..:::... :: .. . .. .: .:: .:. ::... ..: :::..::. CCDS10 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM 640 650 660 670 680 690 150 160 170 180 190 200 pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA : :::: ::::. : . :..:. .. ::. : .:..:.::..: :. : .. :. : CCDS10 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR 700 710 720 730 740 750 210 220 230 240 250 pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL . . . .: . : . : ::.:.: :..: : CCDS10 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG 760 770 780 790 >>CCDS72697.1 H6PD gene_id:9563|Hs108|chr1 (802 aa) initn: 291 init1: 174 opt: 354 Z-score: 405.6 bits: 84.3 E(32554): 2.9e-16 Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:566-799) 10 20 30 pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA :.:.. :.:: . ::. . .:. : CCDS72 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR 540 550 560 570 580 590 40 50 60 70 80 90 pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY : ..: :.::::: : ..: :.: : : :. : . ::: ::.. ::.. CCDS72 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL 600 610 620 630 640 100 110 120 130 140 pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV ..:::... :: .. . .. .: .:: .:. ::... ..: :::..::. CCDS72 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM 650 660 670 680 690 700 150 160 170 180 190 200 pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA : :::: ::::. : . :..:. .. ::. : .:..:.::..: :. : .. :. : CCDS72 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR 710 720 730 740 750 760 210 220 230 240 250 pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL . . . .: . : . : ::.:.: :..: : CCDS72 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG 770 780 790 800 258 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 9 12:17:33 2016 done: Wed Nov 9 12:17:33 2016 Total Scan time: 2.770 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]